CA2298540A1 - Nucleic acid sequences encoding capsaicin receptor and capsaicin receptor-related polypeptides and uses thereof - Google Patents
Nucleic acid sequences encoding capsaicin receptor and capsaicin receptor-related polypeptides and uses thereof Download PDFInfo
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- CA2298540A1 CA2298540A1 CA002298540A CA2298540A CA2298540A1 CA 2298540 A1 CA2298540 A1 CA 2298540A1 CA 002298540 A CA002298540 A CA 002298540A CA 2298540 A CA2298540 A CA 2298540A CA 2298540 A1 CA2298540 A1 CA 2298540A1
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- capsaicin receptor
- capsaicin
- leu
- polypeptide
- receptor
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US91546197A | 1997-08-20 | 1997-08-20 | |
| US08/915,461 | 1997-08-20 | ||
| US7215198P | 1998-01-22 | 1998-01-22 | |
| US60/072,151 | 1998-01-22 | ||
| PCT/US1998/017466 WO1999009140A1 (en) | 1997-08-20 | 1998-08-20 | Nucleic acid sequences encoding capsaicin receptor and capsaicin receptor-related polypeptides and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2298540A1 true CA2298540A1 (en) | 1999-02-25 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002298540A Abandoned CA2298540A1 (en) | 1997-08-20 | 1998-08-20 | Nucleic acid sequences encoding capsaicin receptor and capsaicin receptor-related polypeptides and uses thereof |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US6335180B1 (https=) |
| EP (1) | EP1009804B1 (https=) |
| JP (1) | JP4444493B2 (https=) |
| AT (1) | ATE253111T1 (https=) |
| AU (1) | AU742391B2 (https=) |
| CA (1) | CA2298540A1 (https=) |
| DE (1) | DE69819345T2 (https=) |
| WO (1) | WO1999009140A1 (https=) |
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| WO1999009140A1 (en) | 1997-08-20 | 1999-02-25 | The Regents Of The University Of California | Nucleic acid sequences encoding capsaicin receptor and capsaicin receptor-related polypeptides and uses thereof |
| CA2309903C (en) * | 1998-01-22 | 2012-03-27 | The Regents Of The University Of California | Nucleic acid sequences encoding capsaicin receptor |
| WO1999037765A1 (en) * | 1998-01-27 | 1999-07-29 | Smithkline Beecham Plc | Human vanilloid receptor homologues |
| EP0943683A1 (en) | 1998-03-10 | 1999-09-22 | Smithkline Beecham Plc | Human vanilloid receptor homologue Vanilrep1 |
| EP0953638A1 (en) * | 1998-03-11 | 1999-11-03 | Synthelabo | Human vanilloid receptor-like cation channel |
| US6906178B2 (en) | 1998-08-11 | 2005-06-14 | Human Genome Sciences, Inc. | Vanilloid receptor-2 |
| EP1131433A1 (en) * | 1998-11-13 | 2001-09-12 | Millennium Pharmaceuticals, Inc. | Members of the capsaicin/vanilloid receptor family of proteins and uses thereof |
| US7063951B1 (en) | 1998-11-13 | 2006-06-20 | Millennium Pharmaceuticals, Inc. | Members of the capsaicin/vanilloid receptor family of proteins and uses thereof |
| GB9826359D0 (en) * | 1998-12-01 | 1999-01-27 | Glaxo Group Ltd | Novel receptors |
| GB9827016D0 (en) | 1998-12-08 | 1999-02-03 | Merck Sharp & Dohme | Receptor protein |
| GB9907097D0 (en) * | 1999-03-26 | 1999-05-19 | Novartis Ag | Organic compounds |
| CA2370570A1 (en) * | 1999-04-15 | 2000-10-26 | Adrienne Dubin | Dna encoding the human vanilloid receptor vr1 |
| US6421613B1 (en) * | 1999-07-09 | 2002-07-16 | Pioneer Hi-Bred International, Inc. | Data processing of the maize prolifera genetic sequence |
| US6482611B1 (en) | 1999-09-23 | 2002-11-19 | Neurogen Corporation | Human capsaicin receptor and uses thereof |
| US6455278B1 (en) * | 2000-02-08 | 2002-09-24 | Ortho-Mcneil Pharmaceutical, Inc. | DNA encoding human vanilloid receptor VR3 |
| HUP0300489A3 (en) * | 2000-02-25 | 2006-06-28 | Daiichi Seiyaku Co | Novel protein and gene encoding the same |
| DE10043674A1 (de) * | 2000-09-02 | 2002-03-21 | Gruenenthal Gmbh | Antisense Oligonukleotide |
| AU2001295531A1 (en) * | 2000-09-02 | 2002-03-13 | Grünenthal GmbH | Antisense oligonucleotides against vanilloid receptor 1 |
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| US20030027164A1 (en) * | 2000-12-01 | 2003-02-06 | Gaughan Glen T. | Novel human nucleic acid molecules and polypeptides encoding a novel human ion channel expressed in spinal cord and brain |
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| GB0128161D0 (en) * | 2001-11-23 | 2002-01-16 | Merck Sharp & Dohme | Receptor protein |
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| AU2002318168B2 (en) | 2002-02-25 | 2007-12-13 | Vaxiion Therapeutics, Llc | Minicell compositions and methods |
| US6974818B2 (en) * | 2002-03-01 | 2005-12-13 | Euro-Celtique S.A. | 1,2,5-thiadiazol-3-YL-piperazine therapeutic agents useful for treating pain |
| EP1497328A2 (en) * | 2002-04-16 | 2005-01-19 | Bayer HealthCare AG | Regulation of human transient receptor potential channel |
| EP1532452A4 (en) * | 2002-05-31 | 2006-11-29 | Sloan Kettering Inst Cancer | HETEROLOGY STIMULUS-CONTROLLED ION CHANNELS AND METHOD FOR USE THEREOF |
| AR041191A1 (es) | 2002-08-08 | 2005-05-04 | Amgen Inc | Ligandos del receptor vanilloide y su uso en tratamientos |
| AU2003259846A1 (en) * | 2002-08-16 | 2004-03-03 | The General Hospital Corporation | Non-invasive functional imaging of peripheral nervous system activation in humans and animals |
| US7582635B2 (en) | 2002-12-24 | 2009-09-01 | Purdue Pharma, L.P. | Therapeutic agents useful for treating pain |
| US20050085652A1 (en) * | 2003-04-08 | 2005-04-21 | Algorx Pharmaceuticals, Inc. | Preparation and purification of synthetic capsaicin |
| TWI287010B (en) * | 2003-06-12 | 2007-09-21 | Euro Celtique Sa | Therapeutic agents useful for treating pain |
| WO2005006881A2 (en) * | 2003-07-09 | 2005-01-27 | Virginia Commonwealth University | Salt taste modification |
| DE602004017316D1 (de) | 2003-07-24 | 2008-12-04 | Euro Celtique Sa | Heteroaryl-tetrahydropyridylverbindungen, die sich für die behandlung bzw. die prävention von schmerzen eignen |
| GEP20094676B (en) * | 2003-07-24 | 2009-05-10 | Euro Celtique Sa | Piperidine compounds and pharmaceutical compositions containing them |
| EP1867644B1 (en) | 2003-07-24 | 2009-05-20 | Euro-Celtique S.A. | Heteroaryl-tetrahydropiperidyl compounds useful for treating or preventing pain |
| WO2005012287A1 (en) * | 2003-08-01 | 2005-02-10 | Euro-Celtique S.A. | Therapeutic agents useful for treating pain |
| SI1664016T1 (sl) * | 2003-09-22 | 2009-04-30 | Euro Celtique Sa | Terapevtska sredstva, uporabna za zdravljenje bolečine |
| PL1664041T3 (pl) * | 2003-09-22 | 2008-12-31 | Euro Celtique Sa | Przydatne do leczenia bólu związki fenylowo-karboksyamidowe |
| PL1727801T3 (pl) * | 2003-12-30 | 2009-08-31 | Euro Celtique Sa | Piperazyny użyteczne do leczenia bólu |
| US20070159522A1 (en) * | 2004-02-20 | 2007-07-12 | Harmut Neven | Image-based contextual advertisement method and branded barcodes |
| US7751805B2 (en) * | 2004-02-20 | 2010-07-06 | Google Inc. | Mobile image-based information retrieval system |
| US20050266435A1 (en) * | 2004-03-09 | 2005-12-01 | David Hackos | VR1 receptors and uses thereof |
| GB0412769D0 (en) | 2004-06-08 | 2004-07-07 | Novartis Ag | Organic compounds |
| AU2005309586A1 (en) * | 2004-11-24 | 2006-06-01 | Algorx Pharmaceuticals, Inc. | Capsaicinoid gel formulation and uses thereof |
| EP2500429A3 (en) * | 2005-05-31 | 2015-10-28 | Devgen N.V. | RNAi for the control of insects and arachnids |
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| US8679096B2 (en) | 2007-06-21 | 2014-03-25 | Board Of Regents Of The University Of Nebraska | Multifunctional operational component for robotic devices |
| US20080153845A1 (en) * | 2006-10-27 | 2008-06-26 | Redpoint Bio Corporation | Trpv1 antagonists and uses thereof |
| MX2009011601A (es) | 2007-04-27 | 2009-11-10 | Purdue Pharma Lp | Agentes terapeuticos utiles para tratar el dolor. |
| CA2685266C (en) * | 2007-04-27 | 2014-01-28 | Purdue Pharma L.P. | Trpv1 antagonists and uses thereof for the treatment of prevention of pain, ui and ulcer, ibd, or ibs in an animal |
| EP2170564A4 (en) | 2007-07-12 | 2015-10-07 | Univ Nebraska | ACTUATING PROCESSES AND SYSTEMS IN ROBOTIC EQUIPMENT |
| JP2010536435A (ja) | 2007-08-15 | 2010-12-02 | ボード オブ リージェンツ オブ ザ ユニバーシティ オブ ネブラスカ | 医療用膨張、取り付けおよび送達装置、ならびに関連する方法 |
| WO2009114143A1 (en) * | 2008-03-12 | 2009-09-17 | Brown University | Treatment and prophylaxis of epilepsy and febrile seizures |
| US8546388B2 (en) * | 2008-10-24 | 2013-10-01 | Purdue Pharma L.P. | Heterocyclic TRPV1 receptor ligands |
| US8703962B2 (en) * | 2008-10-24 | 2014-04-22 | Purdue Pharma L.P. | Monocyclic compounds and their use as TRPV1 ligands |
| US8759362B2 (en) * | 2008-10-24 | 2014-06-24 | Purdue Pharma L.P. | Bicycloheteroaryl compounds and their use as TRPV1 ligands |
| WO2010124200A2 (en) * | 2009-04-23 | 2010-10-28 | Transposagen Biopharmaceuticals, Inc. | Genetically modified rat models for cancer |
| EP2449112A1 (en) | 2009-07-01 | 2012-05-09 | Transposagen Biopharmaceuticals, Inc. | Genetically modified rat models for severe combined immunodeficiency (scid) |
| WO2011014721A2 (en) * | 2009-07-30 | 2011-02-03 | Transposagen Biopharmaceuticals, Inc. | Genetically modified rat models for pharmacokinetics |
| WO2011017518A2 (en) * | 2009-08-05 | 2011-02-10 | Transposagen Biopharmaceuticals, Inc. | Genetically modified rat models for drug metabolism |
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| WO2013048595A1 (en) | 2011-06-10 | 2013-04-04 | Board Of Regents Of The University Of Nebraska | Methods, systems, and devices relating to surgical end effectors |
| PE20141531A1 (es) | 2011-06-22 | 2014-10-23 | Purdue Pharma Lp | Antagonistas de trpv1 que incluyen sustituyentes dihidroxi y sus usos |
| EP3588217A1 (en) | 2011-07-11 | 2020-01-01 | Board of Regents of the University of Nebraska | Robotic surgical devices, systems and related methods |
| AU2012293417A1 (en) | 2011-08-10 | 2013-05-02 | Purdue Pharma L.P. | TRPV1 antagonists including dihydroxy substituent and uses thereof |
| EP3730031A1 (en) | 2011-10-03 | 2020-10-28 | Board of Regents of the University of Nebraska | Robotic surgical devices and systems |
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| EP4234185A3 (en) | 2012-06-22 | 2023-09-20 | Board of Regents of the University of Nebraska | Local control robotic surgical devices |
| CA2880622C (en) | 2012-08-08 | 2021-01-12 | Board Of Regents Of The University Of Nebraska | Robotic surgical devices, systems and related methods |
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| US9770305B2 (en) | 2012-08-08 | 2017-09-26 | Board Of Regents Of The University Of Nebraska | Robotic surgical devices, systems, and related methods |
| WO2014152418A1 (en) | 2013-03-14 | 2014-09-25 | Board Of Regents Of The University Of Nebraska | Methods, systems, and devices relating to force control surgical systems |
| US9743987B2 (en) | 2013-03-14 | 2017-08-29 | Board Of Regents Of The University Of Nebraska | Methods, systems, and devices relating to robotic surgical devices, end effectors, and controllers |
| WO2014144220A1 (en) | 2013-03-15 | 2014-09-18 | Board Of Regents Of The University Of Nebraska | Robotic surgical devices, systems, and related methdos |
| CA2918531A1 (en) | 2013-07-17 | 2015-01-22 | Board Of Regents Of The University Of Nebraska | Robotic surgical devices, systems and related methods |
| CN106537149A (zh) | 2014-04-01 | 2017-03-22 | 宝洁公司 | 用于筛选色氨酸通道的方法 |
| WO2016040946A1 (en) | 2014-09-12 | 2016-03-17 | Board Of Regents Of University Of Nebraska | Quick-release end effectors and related systems and methods |
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| US5074977A (en) | 1987-05-05 | 1991-12-24 | The Washington Technology Center | Digital biosensors and method of using same |
| US5234566A (en) | 1988-08-18 | 1993-08-10 | Australian Membrane And Biotechnology Research Institute Ltd. | Sensitivity and selectivity of ion channel biosensor membranes |
| ES2102364T3 (es) | 1989-01-27 | 1997-08-01 | Au Membrane & Biotech Res Inst | Membranas receptoras y control del paso a su traves por medio de ionoforos. |
| US5491097A (en) | 1989-06-15 | 1996-02-13 | Biocircuits Corporation | Analyte detection with multilayered bioelectronic conductivity sensors |
| US5328847A (en) | 1990-02-20 | 1994-07-12 | Case George D | Thin membrane sensor with biochemical switch |
| US5232684A (en) * | 1990-06-29 | 1993-08-03 | The United States Of America As Represented By The Department Of Health And Human Services | Labelled resiniferatoxin, compositions thereof, and methods for using the same |
| WO1999009140A1 (en) | 1997-08-20 | 1999-02-25 | The Regents Of The University Of California | Nucleic acid sequences encoding capsaicin receptor and capsaicin receptor-related polypeptides and uses thereof |
| WO1999037765A1 (en) | 1998-01-27 | 1999-07-29 | Smithkline Beecham Plc | Human vanilloid receptor homologues |
| EP0943683A1 (en) | 1998-03-10 | 1999-09-22 | Smithkline Beecham Plc | Human vanilloid receptor homologue Vanilrep1 |
| EP0953638A1 (en) | 1998-03-11 | 1999-11-03 | Synthelabo | Human vanilloid receptor-like cation channel |
| EP1131433A1 (en) | 1998-11-13 | 2001-09-12 | Millennium Pharmaceuticals, Inc. | Members of the capsaicin/vanilloid receptor family of proteins and uses thereof |
| GB9826359D0 (en) * | 1998-12-01 | 1999-01-27 | Glaxo Group Ltd | Novel receptors |
| CA2370570A1 (en) | 1999-04-15 | 2000-10-26 | Adrienne Dubin | Dna encoding the human vanilloid receptor vr1 |
| EP1144628A3 (en) | 1999-11-12 | 2002-02-27 | Abbott Laboratories | Human vanilloid receptor gene |
| WO2001068857A2 (en) | 2000-03-15 | 2001-09-20 | Millennium Pharmaceuticals, Inc. | 18615 and 48003, human ion channels and uses therefor |
| JP3501775B2 (ja) | 2000-05-31 | 2004-03-02 | ファイザー株式会社 | ヒトバニロイド受容体様タンパク質 |
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- 1998-08-20 CA CA002298540A patent/CA2298540A1/en not_active Abandoned
- 1998-08-20 EP EP98943332A patent/EP1009804B1/en not_active Expired - Lifetime
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1999
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2001
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2004
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| WO1999009140A1 (en) | 1999-02-25 |
| DE69819345T2 (de) | 2004-07-15 |
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| DE69819345D1 (de) | 2003-12-04 |
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| EP1009804B1 (en) | 2003-10-29 |
| US20030049728A1 (en) | 2003-03-13 |
| US20050095650A1 (en) | 2005-05-05 |
| JP4444493B2 (ja) | 2010-03-31 |
| EP1009804A4 (en) | 2001-05-16 |
| US6790629B2 (en) | 2004-09-14 |
| EP1009804A1 (en) | 2000-06-21 |
| US6335180B1 (en) | 2002-01-01 |
| ATE253111T1 (de) | 2003-11-15 |
| AU742391B2 (en) | 2002-01-03 |
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