ATE253111T1 - Für den capsaicin rezeptor kodierende nukleinsäuresequenzen und dem capsaicin rezeptor ähnliche polypeptide und ihre verwendung - Google Patents

Für den capsaicin rezeptor kodierende nukleinsäuresequenzen und dem capsaicin rezeptor ähnliche polypeptide und ihre verwendung

Info

Publication number
ATE253111T1
ATE253111T1 AT98943332T AT98943332T ATE253111T1 AT E253111 T1 ATE253111 T1 AT E253111T1 AT 98943332 T AT98943332 T AT 98943332T AT 98943332 T AT98943332 T AT 98943332T AT E253111 T1 ATE253111 T1 AT E253111T1
Authority
AT
Austria
Prior art keywords
capsaicin receptor
receptor
polypeptides
capsaicin
related aspects
Prior art date
Application number
AT98943332T
Other languages
German (de)
English (en)
Inventor
David J Julius
Michael Caterina
Anthony Brake
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Application granted granted Critical
Publication of ATE253111T1 publication Critical patent/ATE253111T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT98943332T 1997-08-20 1998-08-20 Für den capsaicin rezeptor kodierende nukleinsäuresequenzen und dem capsaicin rezeptor ähnliche polypeptide und ihre verwendung ATE253111T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US91546197A 1997-08-20 1997-08-20
US7215198P 1998-01-22 1998-01-22
PCT/US1998/017466 WO1999009140A1 (en) 1997-08-20 1998-08-20 Nucleic acid sequences encoding capsaicin receptor and capsaicin receptor-related polypeptides and uses thereof

Publications (1)

Publication Number Publication Date
ATE253111T1 true ATE253111T1 (de) 2003-11-15

Family

ID=26753050

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98943332T ATE253111T1 (de) 1997-08-20 1998-08-20 Für den capsaicin rezeptor kodierende nukleinsäuresequenzen und dem capsaicin rezeptor ähnliche polypeptide und ihre verwendung

Country Status (8)

Country Link
US (3) US6335180B1 (https=)
EP (1) EP1009804B1 (https=)
JP (1) JP4444493B2 (https=)
AT (1) ATE253111T1 (https=)
AU (1) AU742391B2 (https=)
CA (1) CA2298540A1 (https=)
DE (1) DE69819345T2 (https=)
WO (1) WO1999009140A1 (https=)

Families Citing this family (97)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6444440B1 (en) 1997-03-07 2002-09-03 Human Genome Sciences, Inc. Vanilloid receptor-2
AU742391B2 (en) 1997-08-20 2002-01-03 Regents Of The University Of California, The Nucleic acid sequences encoding capsaicin receptor and capsaicin receptor-related polypeptides and uses thereof
CA2309903C (en) * 1998-01-22 2012-03-27 The Regents Of The University Of California Nucleic acid sequences encoding capsaicin receptor
EP1066381A1 (en) * 1998-01-27 2001-01-10 Smithkline Beecham Plc Human vanilloid receptor homologues
EP0943683A1 (en) * 1998-03-10 1999-09-22 Smithkline Beecham Plc Human vanilloid receptor homologue Vanilrep1
EP0953638A1 (en) * 1998-03-11 1999-11-03 Synthelabo Human vanilloid receptor-like cation channel
US6906178B2 (en) 1998-08-11 2005-06-14 Human Genome Sciences, Inc. Vanilloid receptor-2
AU2148000A (en) * 1998-11-13 2000-06-05 Millennium Pharmaceuticals, Inc. Novel members of the capsaicin/vanilloid receptor family of proteins and uses thereof
US7063951B1 (en) 1998-11-13 2006-06-20 Millennium Pharmaceuticals, Inc. Members of the capsaicin/vanilloid receptor family of proteins and uses thereof
GB9826359D0 (en) * 1998-12-01 1999-01-27 Glaxo Group Ltd Novel receptors
GB9827016D0 (en) 1998-12-08 1999-02-03 Merck Sharp & Dohme Receptor protein
GB9907097D0 (en) 1999-03-26 1999-05-19 Novartis Ag Organic compounds
AU4237400A (en) * 1999-04-15 2000-11-02 Ortho-Mcneil Pharmaceutical, Inc. Dna encoding the human vanilloid receptor vr1
US6421613B1 (en) * 1999-07-09 2002-07-16 Pioneer Hi-Bred International, Inc. Data processing of the maize prolifera genetic sequence
US6482611B1 (en) 1999-09-23 2002-11-19 Neurogen Corporation Human capsaicin receptor and uses thereof
US6455278B1 (en) * 2000-02-08 2002-09-24 Ortho-Mcneil Pharmaceutical, Inc. DNA encoding human vanilloid receptor VR3
AU2001234150A1 (en) * 2000-02-25 2001-09-03 Daiichi Pharmaceutical Co., Ltd. Novel protein and gene encoding the same
DE10043674A1 (de) * 2000-09-02 2002-03-21 Gruenenthal Gmbh Antisense Oligonukleotide
NZ524894A (en) * 2000-09-02 2005-03-24 Gruenenthal Chemie Antisense oligonucleotides against VR1
US7112685B2 (en) 2000-10-10 2006-09-26 Ortho-Mcneil Pharmaceutical, Inc. Labeled resiniferatoxin derivatives
JP2004511803A (ja) 2000-10-16 2004-04-15 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド バニロイド受容体についての改良リガンド結合アッセイ
CA2436941A1 (en) * 2000-12-01 2002-06-06 Bristol-Myers Squibb Company Novel human nucleic acid molecules and polypeptides encoding a novel human ion channel expressed in spinal cord and brain
US20030171275A1 (en) * 2000-12-20 2003-09-11 Baughn Mariah R. Transporters and ion channels
GB0128161D0 (en) * 2001-11-23 2002-01-16 Merck Sharp & Dohme Receptor protein
WO2003066595A2 (en) 2002-02-01 2003-08-14 Euro-Celtique S.A. 2 - piperazine - pyridines useful for treating pain
CA2517027A1 (en) 2002-02-25 2003-09-04 Vaxiion Therapeutics, Inc. Minicell compositions and methods
US6974818B2 (en) 2002-03-01 2005-12-13 Euro-Celtique S.A. 1,2,5-thiadiazol-3-YL-piperazine therapeutic agents useful for treating pain
WO2003087158A2 (en) * 2002-04-16 2003-10-23 Bayer Healthcare Ag Regulation of human transient receptor potential channel
US7883846B2 (en) * 2002-05-31 2011-02-08 Sloan-Kettering Institute For Cancer Research Heterologous stimulus-gated ion channels and methods of using same
BR0313255A (pt) 2002-08-08 2005-07-12 Amgen Inc Composto, composição farmacêutica, uso de um composto e métodos de fabricar um medicamento e de preparar um composto
AU2003259846A1 (en) * 2002-08-16 2004-03-03 The General Hospital Corporation Non-invasive functional imaging of peripheral nervous system activation in humans and animals
US7582635B2 (en) * 2002-12-24 2009-09-01 Purdue Pharma, L.P. Therapeutic agents useful for treating pain
EP1615880A4 (en) * 2003-04-08 2007-03-07 Algorx Pharmaceuticals Inc PREPARATION AND CLEANING OF SYNTHETIC TRANS CAPSAICIN
MY142655A (en) * 2003-06-12 2010-12-15 Euro Celtique Sa Therapeutic agents useful for treating pain
WO2005006881A2 (en) * 2003-07-09 2005-01-27 Virginia Commonwealth University Salt taste modification
AU2004259357B2 (en) * 2003-07-24 2010-02-18 Euro-Celtique S.A. Piperidine compounds and pharmaceutical compositions containing them
SI1867644T1 (sl) * 2003-07-24 2009-10-31 Euro Celtique Sa Heteroaril-tetrahidropiperidilne spojine, koristne za zdravljenje ali preprečevanje bolečine
EP1867644B1 (en) 2003-07-24 2009-05-20 Euro-Celtique S.A. Heteroaryl-tetrahydropiperidyl compounds useful for treating or preventing pain
PL1942106T3 (pl) 2003-08-01 2012-02-29 Euro Celtique Sa Środki lecznicze użyteczne do leczenia bólu
EP1664041B1 (en) 2003-09-22 2008-07-02 Euro-Celtique S.A. Phenyl-carboxamide compounds useful for treating pain
PL1664016T3 (pl) * 2003-09-22 2009-04-30 Euro Celtique Sa Środki terapeutyczne przydatne do leczenia bólu
ES2322907T3 (es) * 2003-12-30 2009-07-01 Euro-Celtique S.A. Piperazinas utiles para el tratamiento de dolor.
US7751805B2 (en) * 2004-02-20 2010-07-06 Google Inc. Mobile image-based information retrieval system
US20070159522A1 (en) * 2004-02-20 2007-07-12 Harmut Neven Image-based contextual advertisement method and branded barcodes
US20050266435A1 (en) * 2004-03-09 2005-12-01 David Hackos VR1 receptors and uses thereof
GB0412769D0 (en) 2004-06-08 2004-07-07 Novartis Ag Organic compounds
EA200701131A1 (ru) * 2004-11-24 2007-12-28 Алгоркс Фармасьютикалз, Инк. Гелеобразная препаративная форма капсаициноида и способы её применения
CN101213301B (zh) * 2005-05-31 2013-02-27 德福根有限公司 用于防治昆虫和蜘蛛类动物的RNAi
US8679096B2 (en) 2007-06-21 2014-03-25 Board Of Regents Of The University Of Nebraska Multifunctional operational component for robotic devices
CA2861159C (en) 2006-06-22 2018-02-27 Board Of Regents Of The University Of Nebraska Magnetically coupleable robotic devices and related methods
US20080153845A1 (en) * 2006-10-27 2008-06-26 Redpoint Bio Corporation Trpv1 antagonists and uses thereof
WO2008133973A1 (en) 2007-04-27 2008-11-06 Purdue Pharma L.P. Therapeutic agents useful for treating pain
DK2142529T3 (da) 2007-04-27 2014-02-10 Purdue Pharma Lp Trpv1-antagonister og anvendelser deraf
CA2690808C (en) 2007-07-12 2016-09-27 Board Of Regents Of The University Of Nebraska Methods and systems of actuation in robotic devices
EP2178431A4 (en) 2007-08-15 2017-01-18 Board of Regents of the University of Nebraska Medical inflation, attachment, and delivery devices and related methods
WO2009114143A1 (en) * 2008-03-12 2009-09-17 Brown University Treatment and prophylaxis of epilepsy and febrile seizures
US8703962B2 (en) * 2008-10-24 2014-04-22 Purdue Pharma L.P. Monocyclic compounds and their use as TRPV1 ligands
US8759362B2 (en) * 2008-10-24 2014-06-24 Purdue Pharma L.P. Bicycloheteroaryl compounds and their use as TRPV1 ligands
US8546388B2 (en) * 2008-10-24 2013-10-01 Purdue Pharma L.P. Heterocyclic TRPV1 receptor ligands
WO2010124200A2 (en) * 2009-04-23 2010-10-28 Transposagen Biopharmaceuticals, Inc. Genetically modified rat models for cancer
EP2449112A1 (en) 2009-07-01 2012-05-09 Transposagen Biopharmaceuticals, Inc. Genetically modified rat models for severe combined immunodeficiency (scid)
EP2460016A2 (en) * 2009-07-30 2012-06-06 Transposagen Biopharmaceuticals, Inc. Genetically modified rat models for pharmacokinetics
WO2011017518A2 (en) * 2009-08-05 2011-02-10 Transposagen Biopharmaceuticals, Inc. Genetically modified rat models for drug metabolism
EP2467013A2 (en) * 2009-08-20 2012-06-27 Transposagen Biopharmaceuticals, Inc. Genetically modified rat models for pain
EP4275634A3 (en) 2011-06-10 2024-01-10 Board of Regents of the University of Nebraska Surgical end effector
HRP20170507T1 (hr) 2011-06-22 2017-06-02 Purdue Pharma Lp Trpv1 antagonisti uključujući dihidroksi supstituente i njihove uporabe
WO2013009887A1 (en) 2011-07-11 2013-01-17 Board Of Regents Of The University Of Nebraska Robotic surgical devices, systems and related methods
US9394293B2 (en) 2011-08-10 2016-07-19 Purdue Pharma L.P. TRPV1 antagonists including dihydroxy substituent and uses thereof
EP3730031A1 (en) 2011-10-03 2020-10-28 Board of Regents of the University of Nebraska Robotic surgical devices and systems
WO2013106569A2 (en) 2012-01-10 2013-07-18 Board Of Regents Of The University Of Nebraska Methods, systems, and devices for surgical access and insertion
US9498292B2 (en) 2012-05-01 2016-11-22 Board Of Regents Of The University Of Nebraska Single site robotic device and related systems and methods
JP6228196B2 (ja) 2012-06-22 2017-11-08 ボード オブ リージェンツ オブ ザ ユニバーシティ オブ ネブラスカ ローカル制御ロボット手術デバイス
US9770305B2 (en) 2012-08-08 2017-09-26 Board Of Regents Of The University Of Nebraska Robotic surgical devices, systems, and related methods
US12295680B2 (en) 2012-08-08 2025-05-13 Board Of Regents Of The University Of Nebraska Robotic surgical devices, systems and related methods
EP2882331A4 (en) 2012-08-08 2016-03-23 Univ Nebraska ROBOTIC SURGICAL DEVICES, SYSTEMS AND CORRESPONDING METHODS
CA2905948C (en) 2013-03-14 2022-01-11 Board Of Regents Of The University Of Nebraska Methods, systems, and devices relating to robotic surgical devices, end effectors, and controllers
CA2906672C (en) 2013-03-14 2022-03-15 Board Of Regents Of The University Of Nebraska Methods, systems, and devices relating to force control surgical systems
US10667883B2 (en) 2013-03-15 2020-06-02 Virtual Incision Corporation Robotic surgical devices, systems, and related methods
JP6479790B2 (ja) 2013-07-17 2019-03-06 ボード オブ リージェンツ オブ ザ ユニバーシティ オブ ネブラスカ ロボット外科的デバイス、システムおよび関連する方法
US9427415B2 (en) 2014-04-01 2016-08-30 The Procter & Gamble Company Methods and compositions for modifying sensorial perception
JP6710199B2 (ja) 2014-09-12 2020-06-17 ボード オブ リージェンツ オブ ザ ユニバーシティ オブ ネブラスカ クイックリリースエンドエフェクターおよび関連するシステムおよび方法
EP3217890B1 (en) 2014-11-11 2020-04-08 Board of Regents of the University of Nebraska Robotic device with compact joint design
EP4555965A3 (en) 2015-08-03 2025-07-02 Virtual Incision Corporation Robotic surgical devices, systems and related methods
US10751136B2 (en) 2016-05-18 2020-08-25 Virtual Incision Corporation Robotic surgical devices, systems and related methods
EP3503829A4 (en) 2016-08-25 2020-04-15 Board of Regents of the University of Nebraska QUICKLY RELEASABLE TOOL COUPLING AND RELATED SYSTEMS AND METHODS
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WO2018081189A1 (en) 2016-10-25 2018-05-03 The Procter & Gamble Company Fibrous structures
WO2018081190A1 (en) 2016-10-25 2018-05-03 The Procter & Gamble Company Fibrous structures
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WO2018112199A1 (en) 2016-12-14 2018-06-21 Virtual Incision Corporation Releasable attachment device for coupling to medical devices and related systems and methods
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GB201918103D0 (en) 2019-12-10 2020-01-22 Oblique Therapeutics Ab Epitopes and antibodies
CN115843233A (zh) 2020-07-06 2023-03-24 虚拟切割有限公司 手术机器人定位系统及相关装置和方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5074977A (en) 1987-05-05 1991-12-24 The Washington Technology Center Digital biosensors and method of using same
EP0432188B1 (en) 1988-08-18 1996-03-27 AUSTRALIAN MEMBRANE AND BIOTECHNOLOGY RESEARCH INSTITUTE LTD. Commonwealth Scientific and Industrial Research Organization Improvements in sensitivity and selectivity of ion channel membrane biosensors
CA2045640C (en) 1989-01-27 1999-01-05 Bruce Andrew Cornell Receptor membranes and ionophore gating
US5491097A (en) 1989-06-15 1996-02-13 Biocircuits Corporation Analyte detection with multilayered bioelectronic conductivity sensors
US5328847A (en) 1990-02-20 1994-07-12 Case George D Thin membrane sensor with biochemical switch
US5232684A (en) * 1990-06-29 1993-08-03 The United States Of America As Represented By The Department Of Health And Human Services Labelled resiniferatoxin, compositions thereof, and methods for using the same
AU742391B2 (en) 1997-08-20 2002-01-03 Regents Of The University Of California, The Nucleic acid sequences encoding capsaicin receptor and capsaicin receptor-related polypeptides and uses thereof
EP1066381A1 (en) 1998-01-27 2001-01-10 Smithkline Beecham Plc Human vanilloid receptor homologues
EP0943683A1 (en) * 1998-03-10 1999-09-22 Smithkline Beecham Plc Human vanilloid receptor homologue Vanilrep1
EP0953638A1 (en) 1998-03-11 1999-11-03 Synthelabo Human vanilloid receptor-like cation channel
AU2148000A (en) 1998-11-13 2000-06-05 Millennium Pharmaceuticals, Inc. Novel members of the capsaicin/vanilloid receptor family of proteins and uses thereof
GB9826359D0 (en) * 1998-12-01 1999-01-27 Glaxo Group Ltd Novel receptors
AU4237400A (en) 1999-04-15 2000-11-02 Ortho-Mcneil Pharmaceutical, Inc. Dna encoding the human vanilloid receptor vr1
CA2428827A1 (en) 1999-11-12 2001-05-17 Abbott Laboratories Human vanilloid receptor gene
AU2001247460A1 (en) 2000-03-15 2001-09-24 Millennium Pharmaceuticals, Inc. 18615 and 48003, human ion channels and uses therefor
JP3501775B2 (ja) 2000-05-31 2004-03-02 ファイザー株式会社 ヒトバニロイド受容体様タンパク質

Also Published As

Publication number Publication date
EP1009804A1 (en) 2000-06-21
DE69819345D1 (de) 2003-12-04
DE69819345T2 (de) 2004-07-15
EP1009804A4 (en) 2001-05-16
US20050095650A1 (en) 2005-05-05
AU9115698A (en) 1999-03-08
JP2001514879A (ja) 2001-09-18
AU742391B2 (en) 2002-01-03
US7097991B2 (en) 2006-08-29
EP1009804B1 (en) 2003-10-29
US20030049728A1 (en) 2003-03-13
JP4444493B2 (ja) 2010-03-31
WO1999009140A1 (en) 1999-02-25
US6335180B1 (en) 2002-01-01
CA2298540A1 (en) 1999-02-25
US6790629B2 (en) 2004-09-14

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