CA2296334C - A dispensing device and method for forming material - Google Patents
A dispensing device and method for forming material Download PDFInfo
- Publication number
- CA2296334C CA2296334C CA2296334A CA2296334A CA2296334C CA 2296334 C CA2296334 C CA 2296334C CA 2296334 A CA2296334 A CA 2296334A CA 2296334 A CA2296334 A CA 2296334A CA 2296334 C CA2296334 C CA 2296334C
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- liquid
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Classifications
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- D—TEXTILES; PAPER
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- D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
- D01D5/00—Formation of filaments, threads, or the like
- D01D5/0007—Electro-spinning
- D01D5/0061—Electro-spinning characterised by the electro-spinning apparatus
- D01D5/0076—Electro-spinning characterised by the electro-spinning apparatus characterised by the collecting device, e.g. drum, wheel, endless belt, plate or grid
- D01D5/0084—Coating by electro-spinning, i.e. the electro-spun fibres are not removed from the collecting device but remain integral with it, e.g. coating of prostheses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0028—Polypeptides; Proteins; Degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0061—Use of materials characterised by their function or physical properties
- A61L26/0076—Sprayable compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/001—Particle size control
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/02—Inhalators with activated or ionised fluids, e.g. electrohydrodynamic [EHD] or electrostatic devices; Ozone-inhalators with radioactive tagged particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B5/00—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
- B05B5/025—Discharge apparatus, e.g. electrostatic spray guns
- B05B5/0255—Discharge apparatus, e.g. electrostatic spray guns spraying and depositing by electrostatic forces only
-
- D—TEXTILES; PAPER
- D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
- D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
- D01D5/00—Formation of filaments, threads, or the like
- D01D5/0007—Electro-spinning
- D01D5/0061—Electro-spinning characterised by the electro-spinning apparatus
- D01D5/0069—Electro-spinning characterised by the electro-spinning apparatus characterised by the spinning section, e.g. capillary tube, protrusion or pin
-
- D—TEXTILES; PAPER
- D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
- D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
- D01D5/00—Formation of filaments, threads, or the like
- D01D5/28—Formation of filaments, threads, or the like while mixing different spinning solutions or melts during the spinning operation; Spinnerette packs therefor
- D01D5/30—Conjugate filaments; Spinnerette packs therefor
- D01D5/34—Core-skin structure; Spinnerette packs therefor
-
- D—TEXTILES; PAPER
- D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
- D06M—TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
- D06M23/00—Treatment of fibres, threads, yarns, fabrics or fibrous goods made from such materials, characterised by the process
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B1/00—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means
- B05B1/02—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means designed to produce a jet, spray, or other discharge of particular shape or nature, e.g. in single drops, or having an outlet of particular shape
- B05B1/04—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means designed to produce a jet, spray, or other discharge of particular shape or nature, e.g. in single drops, or having an outlet of particular shape in flat form, e.g. fan-like, sheet-like
- B05B1/042—Outlets having two planes of symmetry perpendicular to each other, one of them defining the plane of the jet
Landscapes
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Textile Engineering (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Mechanical Engineering (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Anesthesiology (AREA)
- Materials Engineering (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Materials For Medical Uses (AREA)
- Application Of Or Painting With Fluid Materials (AREA)
- Electrostatic Spraying Apparatus (AREA)
- Medicinal Preparation (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Polymerisation Methods In General (AREA)
- Spinning Methods And Devices For Manufacturing Artificial Fibers (AREA)
- Coating Apparatus (AREA)
- Beans For Foods Or Fodder (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA2689364A CA2689364A1 (en) | 1996-07-23 | 1997-07-22 | A dispensing device and method for forming material |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9615387.9A GB9615387D0 (en) | 1996-07-23 | 1996-07-23 | Dispensing device and process |
| GB9615387.9 | 1996-07-23 | ||
| GB9620064.7 | 1996-09-26 | ||
| GBGB9620064.7A GB9620064D0 (en) | 1996-07-23 | 1996-09-26 | Dispensing device and processes |
| PCT/GB1997/001968 WO1998003267A1 (en) | 1996-07-23 | 1997-07-22 | A dispensing device and method for forming material |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2689364A Division CA2689364A1 (en) | 1996-07-23 | 1997-07-22 | A dispensing device and method for forming material |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2296334A1 CA2296334A1 (en) | 1998-01-29 |
| CA2296334C true CA2296334C (en) | 2010-03-16 |
Family
ID=26309735
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2296334A Expired - Fee Related CA2296334C (en) | 1996-07-23 | 1997-07-22 | A dispensing device and method for forming material |
Country Status (7)
| Country | Link |
|---|---|
| EP (2) | EP1388371B1 (enExample) |
| JP (2) | JP4077035B2 (enExample) |
| AT (1) | ATE263629T1 (enExample) |
| AU (1) | AU3628497A (enExample) |
| CA (1) | CA2296334C (enExample) |
| DE (1) | DE69728539T2 (enExample) |
| WO (1) | WO1998003267A1 (enExample) |
Families Citing this family (128)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6433154B1 (en) * | 1997-06-12 | 2002-08-13 | Bristol-Myers Squibb Company | Functional receptor/kinase chimera in yeast cells |
| CN1163937C (zh) * | 1998-02-16 | 2004-08-25 | 松下电器产业株式会社 | 涂料以及采用该涂料的电子管 |
| GB2345010B (en) * | 1998-12-17 | 2002-12-31 | Electrosols Ltd | A delivery device |
| US6397838B1 (en) * | 1998-12-23 | 2002-06-04 | Battelle Pulmonary Therapeutics, Inc. | Pulmonary aerosol delivery device and method |
| US20020081732A1 (en) | 2000-10-18 | 2002-06-27 | Bowlin Gary L. | Electroprocessing in drug delivery and cell encapsulation |
| US7615373B2 (en) | 1999-02-25 | 2009-11-10 | Virginia Commonwealth University Intellectual Property Foundation | Electroprocessed collagen and tissue engineering |
| US6592623B1 (en) | 1999-08-31 | 2003-07-15 | Virginia Commonwealth University Intellectual Property Foundation | Engineered muscle |
| US20020042128A1 (en) * | 2000-09-01 | 2002-04-11 | Bowlin Gary L. | Electroprocessed fibrin-based matrices and tissues |
| GB9910505D0 (en) * | 1999-05-06 | 1999-07-07 | Electrosols Ltd | A method and apparatus for manufacturing consumable tablets |
| US6737447B1 (en) | 1999-10-08 | 2004-05-18 | The University Of Akron | Nitric oxide-modified linear poly(ethylenimine) fibers and uses thereof |
| US6753454B1 (en) | 1999-10-08 | 2004-06-22 | The University Of Akron | Electrospun fibers and an apparatus therefor |
| ATE475399T1 (de) * | 1999-10-08 | 2010-08-15 | Univ Akron | Gesichtsmaske aus elektrogesponnenen fasern und ihre verwendung |
| AU2001238376A1 (en) * | 2000-02-18 | 2001-08-27 | Charge Injection Technologies, Inc. | Method and apparatus for making fibers |
| AU4126601A (en) * | 2000-02-25 | 2001-09-03 | Advanced New Materials Sa | Method and apparatus for spraying a material |
| WO2001070417A2 (en) * | 2000-03-24 | 2001-09-27 | Advanced New Materials S.A | Method and apparatus for applying a material by means of electro hydro dynamic jetting |
| AU2001244391B9 (en) * | 2000-04-03 | 2006-10-05 | Ventaira Pharmaceuticals, Inc. | Devices and formulations |
| AU2001261625B2 (en) * | 2000-05-16 | 2006-04-06 | Regents Of The University Of Minnesota | High mass throughput particle generation using multiple nozzle spraying |
| WO2002032397A2 (en) * | 2000-10-18 | 2002-04-25 | Virginia Commonwealth University Intellectual Property Foundation | Electroprocessing in drug delivery and cell encapsulation |
| SG160201A1 (en) * | 2000-10-18 | 2010-04-29 | Univ Virginia Commonwealth | Electroprocessing in drug delivery and cell encapsulation |
| DE60135019D1 (de) * | 2000-11-17 | 2008-09-04 | Univ Virginia Commonwealth | Elektroverarbeitetes kollagen |
| JP2010163435A (ja) * | 2000-11-17 | 2010-07-29 | Virginia Commonwealth Univ Intellectual Property Foundation | 電気処理されたコラーゲン |
| ES2180405B1 (es) * | 2001-01-31 | 2004-01-16 | Univ Sevilla | Dispositivo y procedimiento para producir chorros liquidos compuestos multicomponentes estacionarios y capsulas multicomponente y/o multicapa de tamaño micro y nanometrico. |
| ZA200306564B (en) | 2001-02-26 | 2004-10-15 | Optinose As | Nasal devices. |
| GB0115227D0 (en) * | 2001-03-22 | 2001-08-15 | Electrosols Ltd | Manufacturing dissolvable dosage forms |
| US20040131673A1 (en) * | 2001-03-22 | 2004-07-08 | Coffee Ronald Alan | Manufacturing dissolvable dosage forms |
| US7891578B2 (en) | 2001-03-22 | 2011-02-22 | Battelle Memorial Institute | Liquid formations for electrohydrodymanic spraying containing polymer and suspended particles |
| US7247338B2 (en) | 2001-05-16 | 2007-07-24 | Regents Of The University Of Minnesota | Coating medical devices |
| US6713011B2 (en) | 2001-05-16 | 2004-03-30 | The Research Foundation At State University Of New York | Apparatus and methods for electrospinning polymeric fibers and membranes |
| US6685956B2 (en) | 2001-05-16 | 2004-02-03 | The Research Foundation At State University Of New York | Biodegradable and/or bioabsorbable fibrous articles and methods for using the articles for medical applications |
| US6821479B1 (en) * | 2001-06-12 | 2004-11-23 | The University Of Akron | Preservation of biological materials using fiber-forming techniques |
| DE10135501A1 (de) * | 2001-07-20 | 2003-01-30 | Wella Ag | Elektrosol-Haarspray |
| US6790455B2 (en) | 2001-09-14 | 2004-09-14 | The Research Foundation At State University Of New York | Cell delivery system comprising a fibrous matrix and cells |
| BRPI0309022A2 (pt) | 2002-04-04 | 2016-11-08 | Univ Akron | conjuntos de fibra não tecida |
| US8367570B2 (en) | 2002-04-04 | 2013-02-05 | The University Of Akron | Mechanically strong absorbent non-woven fibrous mats |
| AU2003223513A1 (en) * | 2002-04-05 | 2003-10-27 | Virginia Commonwealth University Intellectual Property Foundation | Electroprocessing of materials useful in drug delivery and cell encapsulation |
| WO2003099230A2 (en) * | 2002-05-28 | 2003-12-04 | Virginia Commonwealth University Intellectual Property Foundation | Electroprocessed collagen and tissue engineering |
| GB0219618D0 (en) * | 2002-08-22 | 2002-10-02 | Battelle Memorial Institute | Woundcare |
| US7846141B2 (en) | 2002-09-03 | 2010-12-07 | Bluesky Medical Group Incorporated | Reduced pressure treatment system |
| EP1549255A4 (en) | 2002-09-13 | 2007-12-19 | Coopervision Inc | DEVICES AND METHOD FOR IMPROVING THE SEA THICKNESS |
| GB0224986D0 (en) | 2002-10-28 | 2002-12-04 | Smith & Nephew | Apparatus |
| US20050196441A1 (en) * | 2003-11-05 | 2005-09-08 | Dvorsky James E. | Quick dissolving agrochemical and animal health products |
| AU2005207039A1 (en) | 2004-01-22 | 2005-08-04 | Reneker, Darrell | Polymer NO donor predrug nanofiber coating for medical devices and therapy |
| NL1025556C1 (nl) * | 2004-02-24 | 2005-08-26 | Jacob Korevaar | Inrichting en werkwijze voor het toedienen van een fluïdum aan een mens of zoogdier. |
| US7471437B2 (en) | 2004-03-31 | 2008-12-30 | Eastman Kodak Company | Electrochromic materials and devices |
| US10058642B2 (en) | 2004-04-05 | 2018-08-28 | Bluesky Medical Group Incorporated | Reduced pressure treatment system |
| US7909805B2 (en) | 2004-04-05 | 2011-03-22 | Bluesky Medical Group Incorporated | Flexible reduced pressure treatment appliance |
| US8062272B2 (en) | 2004-05-21 | 2011-11-22 | Bluesky Medical Group Incorporated | Flexible reduced pressure treatment appliance |
| US7592277B2 (en) * | 2005-05-17 | 2009-09-22 | Research Triangle Institute | Nanofiber mats and production methods thereof |
| US7762801B2 (en) | 2004-04-08 | 2010-07-27 | Research Triangle Institute | Electrospray/electrospinning apparatus and method |
| US7297305B2 (en) | 2004-04-08 | 2007-11-20 | Research Triangle Institute | Electrospinning in a controlled gaseous environment |
| US7134857B2 (en) | 2004-04-08 | 2006-11-14 | Research Triangle Institute | Electrospinning of fibers using a rotatable spray head |
| GB0409446D0 (en) | 2004-04-28 | 2004-06-02 | Smith & Nephew | Apparatus |
| JP4439517B2 (ja) * | 2004-05-13 | 2010-03-24 | 株式会社ネクスト２１ | 経内視鏡手術に用いる止血と、癒着の防止装置 |
| BRPI0511339A (pt) | 2004-05-20 | 2007-12-04 | Coopervision Inc | revestimentos córneos e correção de aberração de frente de onda para melhorar a visão |
| DE102004026745B4 (de) | 2004-05-28 | 2013-06-20 | Justus-Liebig-Universität Giessen | Verfahren und Vorrichtung zur Ausbringung von nanoskaligen Polymerfasern als Träger für landwirtschaftliche Wirkstoffe |
| US7390760B1 (en) | 2004-11-02 | 2008-06-24 | Kimberly-Clark Worldwide, Inc. | Composite nanofiber materials and methods for making same |
| CA2597321A1 (en) * | 2005-02-11 | 2006-08-17 | Battelle Memorial Institute | Ehd aerosol dispensing device and spraying method |
| CA2608740C (en) | 2005-05-16 | 2015-09-08 | The University Of Akron | Mechanically strong absorbent non-woven fibrous mats |
| DE102005033681A1 (de) * | 2005-07-19 | 2007-02-08 | Kunststoff-Fröhlich GmbH | Plastisch geformter Körper, thermoplastisch verformbares Granulat, Hohlstruktur und Verfahren zu deren Herstellung |
| CA2637883C (en) | 2006-01-31 | 2015-07-07 | Regents Of The University Of Minnesota | Electrospray coating of objects |
| WO2007089883A2 (en) | 2006-01-31 | 2007-08-09 | Nanocopoeia, Inc. | Nanoparticle coating of surfaces |
| US9108217B2 (en) | 2006-01-31 | 2015-08-18 | Nanocopoeia, Inc. | Nanoparticle coating of surfaces |
| US8297959B2 (en) * | 2006-05-03 | 2012-10-30 | Terapia Celular, Ln, Inc. | Systems for producing multilayered particles, fibers and sprays and methods for administering the same |
| WO2007135492A2 (en) | 2006-05-18 | 2007-11-29 | Gustavo Larsen | Methods for making a multicomponent hemostatic dressing |
| US7629030B2 (en) * | 2006-12-05 | 2009-12-08 | Nanostatics, Llc | Electrospraying/electrospinning array utilizing a replacement array of individual tip flow restriction |
| US9040816B2 (en) | 2006-12-08 | 2015-05-26 | Nanocopoeia, Inc. | Methods and apparatus for forming photovoltaic cells using electrospray |
| WO2009042128A1 (en) | 2007-09-25 | 2009-04-02 | The University Of Akron | Bubble launched electrospinning jets |
| GB0722820D0 (en) | 2007-11-21 | 2008-01-02 | Smith & Nephew | Vacuum assisted wound dressing |
| US8808259B2 (en) | 2007-11-21 | 2014-08-19 | T.J. Smith & Nephew Limited | Suction device and dressing |
| HUE049431T2 (hu) | 2007-11-21 | 2020-09-28 | Smith & Nephew | Sebkötözés |
| US20130096518A1 (en) | 2007-12-06 | 2013-04-18 | Smith & Nephew Plc | Wound filling apparatuses and methods |
| US11253399B2 (en) | 2007-12-06 | 2022-02-22 | Smith & Nephew Plc | Wound filling apparatuses and methods |
| GB0723875D0 (en) | 2007-12-06 | 2008-01-16 | Smith & Nephew | Wound management |
| GB0803564D0 (en) | 2008-02-27 | 2008-04-02 | Smith & Nephew | Fluid collection |
| KR101683042B1 (ko) | 2008-04-04 | 2016-12-06 | 포사이트 비젼4, 인크. | 통증 관리 및 시력을 위한 치료 장치 |
| EP2303248B1 (en) * | 2008-04-21 | 2017-05-17 | Johnson & Johnson Consumer Inc. | Dual spray can topical delivery device |
| JP5178309B2 (ja) * | 2008-05-09 | 2013-04-10 | オリンパス株式会社 | 薬液投与装置 |
| GB0902816D0 (en) | 2009-02-19 | 2009-04-08 | Smith & Nephew | Fluid communication path |
| GB0905575D0 (en) | 2009-03-31 | 2009-05-13 | Stfc Science & Technology | Electrospinning nozzle |
| US9498385B2 (en) | 2009-10-23 | 2016-11-22 | Nexisvision, Inc. | Conformable therapeutic shield for vision and pain |
| US20130066283A1 (en) | 2009-10-23 | 2013-03-14 | Nexisvision, Inc. | Corneal Denervation for Treatment of Ocular Pain |
| US8591025B1 (en) | 2012-09-11 | 2013-11-26 | Nexisvision, Inc. | Eye covering and refractive correction methods for LASIK and other applications |
| US9061095B2 (en) | 2010-04-27 | 2015-06-23 | Smith & Nephew Plc | Wound dressing and method of use |
| GB201011173D0 (en) | 2010-07-02 | 2010-08-18 | Smith & Nephew | Provision of wound filler |
| WO2012061160A1 (en) | 2010-10-25 | 2012-05-10 | Nexisvision, Inc. | Methods and apparatus to identify eye coverings for vision |
| GB201020005D0 (en) | 2010-11-25 | 2011-01-12 | Smith & Nephew | Composition 1-1 |
| MX337627B (es) | 2010-11-25 | 2016-03-10 | Smith & Nephew | Composiciones i-ii y productos y usos de la misma. |
| US9194058B2 (en) * | 2011-01-31 | 2015-11-24 | Arsenal Medical, Inc. | Electrospinning process for manufacture of multi-layered structures |
| CA2834295A1 (en) | 2011-04-28 | 2012-11-01 | Nexisvision, Inc. | Eye covering and refractive correction methods and apparatus having improved tear flow, comfort, and/or applicability |
| US12044905B2 (en) | 2011-04-28 | 2024-07-23 | Journey1 Inc | Contact lenses for refractive correction |
| US20150159066A1 (en) | 2011-11-25 | 2015-06-11 | Smith & Nephew Plc | Composition, apparatus, kit and method and uses thereof |
| US9465233B2 (en) | 2012-04-20 | 2016-10-11 | Nexisvision, Inc. | Bimodular contact lenses |
| HK1208268A1 (en) | 2012-04-20 | 2016-02-26 | 内希斯视觉股份有限公司 | Contact lenses for refractive correction |
| US10519434B2 (en) | 2012-07-13 | 2019-12-31 | Diomics Corporation | Biologic sample collection devices and methods of production and use thereof |
| CZ303780B6 (cs) * | 2012-07-27 | 2013-05-02 | Contipro Biotech S.R.O. | Zvláknovací tryska pro výrobu nano a mikrovlákenných materiálu slozených z vláken s koaxiální strukturou |
| EP2703031A1 (en) * | 2012-08-28 | 2014-03-05 | Universität Bern | Electrospray device |
| WO2014120455A1 (en) * | 2013-02-04 | 2014-08-07 | Arsenal Medical, Inc. | Electrospinning process for fiber manufacture |
| US20160120706A1 (en) | 2013-03-15 | 2016-05-05 | Smith & Nephew Plc | Wound dressing sealant and use thereof |
| EP2968647B1 (en) | 2013-03-15 | 2022-06-29 | Smith & Nephew plc | Wound dressing sealant and use thereof |
| JP6310072B2 (ja) | 2013-06-26 | 2018-04-11 | ネクシスビジョン， インコーポレイテッド | 屈折矯正のためのコンタクトレンズ |
| US9341864B2 (en) | 2013-11-15 | 2016-05-17 | Nexisvision, Inc. | Contact lenses having a reinforcing scaffold |
| WO2015116559A1 (en) | 2014-01-29 | 2015-08-06 | Nexisvision, Inc. | Multifocal bimodulus contact lenses |
| EP3166726A4 (en) | 2014-05-01 | 2018-03-07 | Diomics Corporation | Devices and kits for collection, storage and analysis of samples and methods of production and use thereof |
| US20160025603A1 (en) | 2014-07-22 | 2016-01-28 | Diomics Corporation | Airborne agent collectors, methods, systems and devices for monitoring airborne agents |
| US10346671B2 (en) | 2014-08-15 | 2019-07-09 | Diomics Corporation | Films for biologic analyte collection and analysis and methods of production and use thereof |
| JP6117174B2 (ja) | 2014-12-18 | 2017-04-19 | 株式会社東芝 | ナノファイバ製造装置、及び、ナノファイバ製造方法 |
| BR112018007938B1 (pt) | 2015-10-19 | 2021-12-07 | Kao Corporation | Método de formação de revestimento |
| JP6203362B2 (ja) | 2015-10-19 | 2017-09-27 | 花王株式会社 | 被膜の製造方法 |
| EP3364757A1 (en) * | 2015-10-20 | 2018-08-29 | Massachusetts Institute of Technology | Systems and methods for surface retention of fluids |
| US10632228B2 (en) | 2016-05-12 | 2020-04-28 | Acera Surgical, Inc. | Tissue substitute materials and methods for tissue repair |
| BR112019013464A2 (pt) | 2016-12-28 | 2020-01-07 | Kao Corporation | Método para fabricar um filme de revestimento |
| JP7326516B2 (ja) * | 2017-04-18 | 2023-08-15 | 花王株式会社 | 外用薬 |
| JP2018177724A (ja) * | 2017-04-18 | 2018-11-15 | 花王株式会社 | 外用薬 |
| JP2018177725A (ja) * | 2017-04-18 | 2018-11-15 | 花王株式会社 | 外用薬 |
| JP7201768B2 (ja) * | 2017-04-18 | 2023-01-10 | 花王株式会社 | 外用薬 |
| CN110536673A (zh) * | 2017-04-19 | 2019-12-03 | 花王株式会社 | 覆膜形成用组合物 |
| CN110573128B (zh) * | 2017-04-19 | 2022-03-29 | 花王株式会社 | 覆膜的制造方法 |
| JP6509403B2 (ja) * | 2017-04-19 | 2019-05-08 | 花王株式会社 | 被膜の製造方法 |
| EP3613403B1 (en) | 2017-04-19 | 2022-10-05 | Kao Corporation | Method for producing coating film |
| WO2018193066A1 (de) * | 2017-04-21 | 2018-10-25 | J. Wagner Gmbh | Sprühkopf für einen elektrostatischen zerstäuber |
| JP7210468B2 (ja) * | 2017-04-21 | 2023-01-23 | ジェイ． ワグナー ゲーエムベーハー | 液体用静電噴霧器及び静電噴霧器の動作方法 |
| JP6975061B2 (ja) * | 2018-02-06 | 2021-12-01 | 花王株式会社 | 物体の温度調節方法 |
| US20190344274A1 (en) | 2018-03-12 | 2019-11-14 | Massachusetts Institute Of Technology | Articles and systems involving reaction products on surfaces and associated methods |
| WO2020111055A1 (ja) | 2018-11-26 | 2020-06-04 | 花王株式会社 | 皮膚用被膜 |
| CN112030240B (zh) * | 2020-07-13 | 2022-04-29 | 兰州百源基因技术有限公司 | 一种便携式静电纺丝设备 |
| WO2022086756A1 (en) | 2020-10-19 | 2022-04-28 | Journey1, Inc. | Astigmatism correcting contact lenses |
| CN112725908A (zh) * | 2020-12-23 | 2021-04-30 | 青岛大学 | 一种便携式溶液喷射纺丝装置 |
| JP7397958B2 (ja) * | 2021-10-20 | 2023-12-13 | 花王株式会社 | 外用薬 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1527592A (en) * | 1974-08-05 | 1978-10-04 | Ici Ltd | Wound dressing |
| GB1569707A (en) | 1976-07-15 | 1980-06-18 | Ici Ltd | Atomisation of liquids |
| DE2960875D1 (en) * | 1978-04-19 | 1981-12-10 | Ici Plc | A method of preparing a tubular product by electrostatic spinning |
| JPS5665627A (en) * | 1979-11-05 | 1981-06-03 | Agency Of Ind Science & Technol | Method of combining particles of liquid, etc. |
| DE3069807D1 (en) | 1979-11-19 | 1985-01-24 | Ici Plc | Electrostatic spraying apparatus |
| DE3036814C2 (de) * | 1980-09-30 | 1984-10-04 | Fa. Carl Freudenberg, 6940 Weinheim | Wundkompresse und Verfahren zu ihrer Herstellung |
| JPS6057907B2 (ja) * | 1981-06-18 | 1985-12-17 | 工業技術院長 | 液体の混合噴霧化方法 |
| ATE29225T1 (de) | 1982-08-25 | 1987-09-15 | Ici Plc | Pumpe mit elektrostatischem antriebseffekt fuer spritzsystem. |
| US4657793A (en) * | 1984-07-16 | 1987-04-14 | Ethicon, Inc. | Fibrous structures |
| GB8504254D0 (en) * | 1985-02-19 | 1985-03-20 | Ici Plc | Spraying apparatus |
| GB8604328D0 (en) * | 1986-02-21 | 1986-03-26 | Ici Plc | Producing spray of droplets of liquid |
| GB8614566D0 (en) * | 1986-06-16 | 1986-07-23 | Ici Plc | Spraying |
| GB8614564D0 (en) * | 1986-06-16 | 1986-07-23 | Ici Plc | Spraying |
| JPH03161502A (ja) * | 1989-11-20 | 1991-07-11 | I C I Japan Kk | 静電紡糸の製造方法 |
| EP0468736B1 (en) * | 1990-07-25 | 1997-03-19 | Imperial Chemical Industries Plc | Electrostatic spraying device and method |
| WO1994013266A1 (en) * | 1992-05-29 | 1994-06-23 | The Regents Of The University Of California | Novel electrostatic process for manufacturing coated transplants and products |
| GB9225098D0 (en) | 1992-12-01 | 1993-01-20 | Coffee Ronald A | Charged droplet spray mixer |
| RU2034534C1 (ru) * | 1992-12-22 | 1995-05-10 | Товарищество с ограниченной ответственностью - Научно-производственное предприятие "Экомедсервис" | Способ нанесения защитного асептического покрытия и устройство для его осуществления |
| GB9226717D0 (en) | 1992-12-22 | 1993-02-17 | Coffee Ronald A | Induction-operated electro-hydrodynamic spray device with means of modifying droplet trajectories |
| RU2031661C1 (ru) * | 1993-07-16 | 1995-03-27 | Научно-производственное предприятие "Экомедсервис" | Средство для лечения ран и оказания первой медицинской помощи |
| GB9406171D0 (en) | 1994-03-29 | 1994-05-18 | Electrosols Ltd | Dispensing device |
| GB9406255D0 (en) * | 1994-03-29 | 1994-05-18 | Electrosols Ltd | Dispensing device |
-
1997
- 1997-07-22 AU AU36284/97A patent/AU3628497A/en not_active Abandoned
- 1997-07-22 JP JP50670398A patent/JP4077035B2/ja not_active Expired - Fee Related
- 1997-07-22 EP EP03077325A patent/EP1388371B1/en not_active Expired - Lifetime
- 1997-07-22 DE DE69728539T patent/DE69728539T2/de not_active Expired - Lifetime
- 1997-07-22 EP EP97932918A patent/EP0912251B1/en not_active Expired - Lifetime
- 1997-07-22 CA CA2296334A patent/CA2296334C/en not_active Expired - Fee Related
- 1997-07-22 WO PCT/GB1997/001968 patent/WO1998003267A1/en not_active Ceased
- 1997-07-22 AT AT97932918T patent/ATE263629T1/de not_active IP Right Cessation
-
2007
- 2007-06-12 JP JP2007155691A patent/JP4875544B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU3628497A (en) | 1998-02-10 |
| EP1388371A2 (en) | 2004-02-11 |
| CA2296334A1 (en) | 1998-01-29 |
| JP2000516130A (ja) | 2000-12-05 |
| WO1998003267A1 (en) | 1998-01-29 |
| EP0912251A1 (en) | 1999-05-06 |
| DE69728539T2 (de) | 2004-08-05 |
| EP1388371A3 (en) | 2004-03-03 |
| DE69728539D1 (de) | 2004-05-13 |
| EP0912251B1 (en) | 2004-04-07 |
| JP4077035B2 (ja) | 2008-04-16 |
| JP2007325934A (ja) | 2007-12-20 |
| EP1388371B1 (en) | 2009-10-28 |
| JP4875544B2 (ja) | 2012-02-15 |
| ATE263629T1 (de) | 2004-04-15 |
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| EEER | Examination request | ||
| MKLA | Lapsed |
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