DE60135019D1 - Elektroverarbeitetes kollagen - Google Patents

Elektroverarbeitetes kollagen

Info

Publication number
DE60135019D1
DE60135019D1 DE60135019T DE60135019T DE60135019D1 DE 60135019 D1 DE60135019 D1 DE 60135019D1 DE 60135019 T DE60135019 T DE 60135019T DE 60135019 T DE60135019 T DE 60135019T DE 60135019 D1 DE60135019 D1 DE 60135019D1
Authority
DE
Germany
Prior art keywords
collagen
electroprocessed
electrically processed
organs
tissues
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60135019T
Other languages
English (en)
Inventor
David G Simpson
Gary L Bowlin
Gary E Wnek
Peter J Stevens
Marcus E Carr
Jamil A Matthews
Saravanamoorthy Rajendran
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Virginia Commonwealth University
Virginia Commonwealth University Intellectual Property Foundation
Original Assignee
Virginia Commonwealth University
Virginia Commonwealth University Intellectual Property Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/946,158 external-priority patent/US20020042128A1/en
Priority claimed from US09/982,515 external-priority patent/US20020081732A1/en
Priority claimed from PCT/US2001/032301 external-priority patent/WO2002032397A2/en
Application filed by Virginia Commonwealth University, Virginia Commonwealth University Intellectual Property Foundation filed Critical Virginia Commonwealth University
Application granted granted Critical
Publication of DE60135019D1 publication Critical patent/DE60135019D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/26—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/041—Mixtures of macromolecular compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C41/00—Shaping by coating a mould, core or other substrate, i.e. by depositing material and stripping-off the shaped article; Apparatus therefor
    • B29C41/006—Shaping by coating a mould, core or other substrate, i.e. by depositing material and stripping-off the shaped article; Apparatus therefor using an electrostatic field for applying the material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C67/00—Shaping techniques not covered by groups B29C39/00 - B29C65/00, B29C70/00 or B29C73/00
    • B29C67/0007—Manufacturing coloured articles not otherwise provided for, e.g. by colour change
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0012—Cell encapsulation
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
    • D01D5/00—Formation of filaments, threads, or the like
    • D01D5/0007—Electro-spinning
    • D01D5/0015—Electro-spinning characterised by the initial state of the material
    • D01D5/003—Electro-spinning characterised by the initial state of the material the material being a polymer solution or dispersion
    • D01D5/0038—Electro-spinning characterised by the initial state of the material the material being a polymer solution or dispersion the fibre formed by solvent evaporation, i.e. dry electro-spinning
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F1/00—General methods for the manufacture of artificial filaments or the like
    • D01F1/02—Addition of substances to the spinning solution or to the melt
    • D01F1/10—Other agents for modifying properties
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F4/00—Monocomponent artificial filaments or the like of proteins; Manufacture thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/126—Immunoprotecting barriers, e.g. jackets, diffusion chambers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers
    • C12N2533/40—Polyhydroxyacids, e.g. polymers of glycolic or lactic acid (PGA, PLA, PLGA); Bioresorbable polymers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/54—Collagen; Gelatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Dermatology (AREA)
  • Textile Engineering (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Biochemistry (AREA)
  • Mechanical Engineering (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Manufacturing & Machinery (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • Materials Engineering (AREA)
  • Toxicology (AREA)
  • Botany (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
DE60135019T 2000-11-17 2001-11-16 Elektroverarbeitetes kollagen Expired - Lifetime DE60135019D1 (de)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US71425500A 2000-11-17 2000-11-17
US27011801P 2001-02-22 2001-02-22
US09/946,158 US20020042128A1 (en) 2000-09-01 2001-09-04 Electroprocessed fibrin-based matrices and tissues
PCT/US2001/027409 WO2002018441A2 (en) 2000-09-01 2001-09-04 Electroprocessed fibrin-based matrices and tissues
US09/982,515 US20020081732A1 (en) 2000-10-18 2001-10-18 Electroprocessing in drug delivery and cell encapsulation
PCT/US2001/032301 WO2002032397A2 (en) 2000-10-18 2001-10-18 Electroprocessing in drug delivery and cell encapsulation
PCT/US2001/043748 WO2002040242A1 (en) 2000-11-17 2001-11-16 Electroprocessed collagen

Publications (1)

Publication Number Publication Date
DE60135019D1 true DE60135019D1 (de) 2008-09-04

Family

ID=27555667

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60135019T Expired - Lifetime DE60135019D1 (de) 2000-11-17 2001-11-16 Elektroverarbeitetes kollagen

Country Status (8)

Country Link
EP (2) EP1982735A1 (de)
JP (1) JP4485124B2 (de)
AT (1) ATE402002T1 (de)
AU (1) AU2002225700A1 (de)
CA (1) CA2467359C (de)
DE (1) DE60135019D1 (de)
ES (1) ES2312495T3 (de)
WO (1) WO2002040242A1 (de)

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US7579442B2 (en) 2002-04-16 2009-08-25 Ocugenics, LLC Method for stromal corneal repair and refractive alteration
WO2004000915A2 (en) 2002-06-24 2003-12-31 Tufts University Silk biomaterials and methods of use thereof
CA2541334A1 (en) * 2002-10-04 2004-04-22 Virginia Commonwealth University Intellectual Property Foundation Sealants for skin and other tissues
US8545386B2 (en) 2003-08-14 2013-10-01 Boston Scientific Scimed, Inc. Surgical slings
WO2005016184A1 (en) * 2003-08-14 2005-02-24 Scimed Life System, Inc. Surgical slings
DE102004058924A1 (de) 2004-12-07 2006-06-08 Roche Diagnostics Gmbh Testelement mit Nanofasern
WO2007066715A1 (ja) * 2005-12-09 2007-06-14 Osaka University 一軸配向ハイドロゲル
EP2065056B1 (de) * 2006-08-29 2016-09-28 FUJIFILM Corporation Hydrophile matrix enthaltend einer schwer wasserlöslichen verbindung und herstellungsverfahren dafür
WO2008047857A1 (fr) * 2006-10-18 2008-04-24 Fujifilm Corporation Procédé de production d'une composition comprenant un composé difficilement soluble dans l'eau incorporé dans une matrice hydrophile et préparation pour une utilisation externe comprenant un agent ou médicament anticancéreux ayant un coefficient de partage octanol/eau (log p) de -3,0 ou plus mais pas plus de 3,0, incorporé
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FR2917293B1 (fr) * 2007-06-13 2010-11-26 Olivier Paul Christian Schussler Support collagenique modifie par greffage covalent de molecules d'adhesion : procedes et applications pour l'ingenierie de tissu contractile, la therapie cellulaire en thoracique et cardiovasculaire
US7767297B2 (en) 2007-07-30 2010-08-03 Idemitsu Technofine Co., Ltd. Fiber, fiber assembly, and fiber producing method
US9233080B2 (en) * 2008-03-27 2016-01-12 Agigma, Inc. Compositions and methods for the delivery of agents
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PL217525B1 (pl) 2009-11-24 2014-07-31 Politechnika Łódzka Układ do formowania włókien metodą elektroprzędzenia
RU2478475C2 (ru) * 2010-03-09 2013-04-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Ангарская государственная техническая академия" Экструзионный способ получения композитных материалов
US11369465B2 (en) 2013-01-14 2022-06-28 Scripps Health Tissue array printing
WO2015138970A1 (en) * 2014-03-14 2015-09-17 Scripps Health Electrospinning of cartilage and meniscus matrix polymers
EP3169372A4 (de) * 2014-07-17 2018-03-21 The Regents of The University of California Steuerbare selbsthärtende mikrogelpartikel für biomedizinische anwendungen
TWI555521B (zh) * 2014-12-12 2016-11-01 國立清華大學 人工血管及其製造方法
WO2017142879A1 (en) 2016-02-16 2017-08-24 The Regents Of The University Of California Methods for immune system modulation with microporous annealed particle gels
CN107510862B (zh) * 2016-06-15 2020-05-19 中国科学院苏州纳米技术与纳米仿生研究所 担载梯度浓度生物活性分子的有序纤维支架、制法及应用
CN107233611B (zh) * 2017-06-11 2020-07-31 吉林大学第一医院 一种多功能纳米纤维创面修复生物敷料及其制备方法
CN108914223B (zh) * 2018-09-05 2021-06-04 东华大学 一种静电纺丝相位补偿铺网控制系统
CN117482292A (zh) * 2023-09-15 2024-02-02 北京帝康医药投资管理有限公司 一种胶原蛋白多孔微球及其制备方法和应用

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Also Published As

Publication number Publication date
EP1345743B1 (de) 2008-07-23
CA2467359C (en) 2010-11-02
EP1345743A1 (de) 2003-09-24
ATE402002T1 (de) 2008-08-15
EP1982735A1 (de) 2008-10-22
WO2002040242A1 (en) 2002-05-23
AU2002225700A1 (en) 2002-05-27
JP2004523484A (ja) 2004-08-05
JP4485124B2 (ja) 2010-06-16
ES2312495T3 (es) 2009-03-01
CA2467359A1 (en) 2002-05-23

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