ES2162331T3 - Utilizacion del factor de crecimiento del tejido nervioso para conservacion, cultivo o tratamiento de la cornea. - Google Patents

Utilizacion del factor de crecimiento del tejido nervioso para conservacion, cultivo o tratamiento de la cornea.

Info

Publication number
ES2162331T3
ES2162331T3 ES97946052T ES97946052T ES2162331T3 ES 2162331 T3 ES2162331 T3 ES 2162331T3 ES 97946052 T ES97946052 T ES 97946052T ES 97946052 T ES97946052 T ES 97946052T ES 2162331 T3 ES2162331 T3 ES 2162331T3
Authority
ES
Spain
Prior art keywords
growth factor
cornea
crop
conservation
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97946052T
Other languages
English (en)
Inventor
Alessandro Lambiase
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Anabasis SRL
Original Assignee
Anabasis SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anabasis SRL filed Critical Anabasis SRL
Application granted granted Critical
Publication of ES2162331T3 publication Critical patent/ES2162331T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0226—Physiologically active agents, i.e. substances affecting physiological processes of cells and tissue to be preserved, e.g. anti-oxidants or nutrients
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0621—Eye cells, e.g. cornea, iris pigmented cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/13—Nerve growth factor [NGF]; Brain-derived neurotrophic factor [BDNF]; Cilliary neurotrophic factor [CNTF]; Glial-derived neurotrophic factor [GDNF]; Neurotrophins [NT]; Neuregulins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Environmental Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biotechnology (AREA)
  • Dentistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Psychology (AREA)
  • Cell Biology (AREA)
  • Physiology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Utilización del factor de crecimiento de nervios (NGF) para almacenamiento de córneas en cultivo y para almacenamiento y producción in vitro de tejidos corneales y conjuntivales y de poblaciones de células corneales o conjuntivales individuales.
ES97946052T 1997-04-24 1997-11-21 Utilizacion del factor de crecimiento del tejido nervioso para conservacion, cultivo o tratamiento de la cornea. Expired - Lifetime ES2162331T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT97RM000238A IT1291892B1 (it) 1997-04-24 1997-04-24 Uso del nerve growth factor nella conservazione di cornee in coltura, nella produzione di tessuti corneali e congiuntivali in vitro e nella

Publications (1)

Publication Number Publication Date
ES2162331T3 true ES2162331T3 (es) 2001-12-16

Family

ID=11405005

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97946052T Expired - Lifetime ES2162331T3 (es) 1997-04-24 1997-11-21 Utilizacion del factor de crecimiento del tejido nervioso para conservacion, cultivo o tratamiento de la cornea.

Country Status (15)

Country Link
US (2) US6537808B2 (es)
EP (1) EP0973872B1 (es)
JP (1) JP3973697B2 (es)
AT (1) ATE203054T1 (es)
AU (1) AU734801B2 (es)
CA (1) CA2287780C (es)
DE (1) DE69705643T2 (es)
DK (1) DK0973872T3 (es)
EA (1) EA002986B1 (es)
ES (1) ES2162331T3 (es)
GR (1) GR3036859T3 (es)
IL (1) IL132473A0 (es)
IT (1) IT1291892B1 (es)
PT (1) PT973872E (es)
WO (1) WO1998048002A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6849612B2 (en) * 1993-01-21 2005-02-01 Isis Pharmaceuticals, Inc. Oligonucleotide modulation of cell adhesion
IT1305294B1 (it) * 1999-01-29 2001-05-04 Alessandro Lambiase Uso del nerve growth factor nella terapia di patologie a carico deitessuti intraoculari.
AU7907301A (en) * 2000-07-28 2002-02-13 Christopher J Murphy Transplant media
FR2825273B1 (fr) * 2001-05-29 2006-11-24 Oreal Composition pour le traitement des signes cutanes du vieillissement
DE10313341A1 (de) * 2003-03-25 2004-10-14 Scil Proteins Gmbh Verwendung von proNGF, insbesondere zur Wundheilung der Cornea und der Haut
NZ550542A (en) 2004-03-30 2009-03-31 Nsgene As Therapeutic use of a growth factor, NsG33
AU2005296212A1 (en) * 2004-10-19 2006-04-27 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Topical treatment with NGF and DHA in damaged corneas
ITRM20050447A1 (it) * 2005-08-19 2007-02-20 Anabasis S R L Uso del nerve growth factor in collirio nella terapia di patologie del sistema nervoso centrale, quali la malattia di alzheimer e il morbo di parkinson.
WO2012073238A1 (en) * 2010-12-02 2012-06-07 Technion Research & Development Foundation Ltd. Methods of generating corneal cells and cell populations comprising same
US9974646B2 (en) 2012-09-05 2018-05-22 University Of Miami Keratoprosthesis, and system and method of corneal repair using same
MA41906A (fr) * 2015-04-10 2018-02-13 Dompe Farm Spa Dispositif de distribution de gouttes oculaires
ITUA20162072A1 (it) 2016-06-30 2017-12-30 Platinum Corp Srl Dropper a volume controllato
CN107137698A (zh) * 2017-03-03 2017-09-08 北京大学第三医院 一种包含gdnf的用于治疗角膜上皮损伤的药物组合物

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4959319A (en) * 1985-08-01 1990-09-25 Skelnik Debra L Process of corneal enhancement
NZ226171A (en) * 1987-09-18 1990-06-26 Ethicon Inc Gel formulation containing polypeptide growth factor
DE3827477A1 (de) 1988-08-12 1990-02-22 Biotechnolog Forschung Gmbh Verfahren zur isolierung und zur alleinigen zuechtung von endothelialzellen der menschlichen hornhaut (hcec)
US5360611A (en) * 1988-10-03 1994-11-01 Alcon Laboratories, Inc. Pharmaceutical compositions and methods of treatment of the cornea following ultraviolet laser irradiation
WO1992002247A1 (en) * 1990-08-01 1992-02-20 Chiron Ophthalmics, Inc. Method for treating corneal endothelial wounds
US5641479A (en) * 1991-02-12 1997-06-24 Richardson-Vicks Inc. Cosmetic compositions comprising an imidazolium derivative and branched polyethylene glycol
US5272135A (en) * 1991-03-01 1993-12-21 Chiron Ophthalmics, Inc. Method for the stabilization of methionine-containing polypeptides
IT1255657B (it) 1992-05-29 1995-11-09 Colture di tessuto di mucosa congiuntivale differenziata, procedimentoper la loro preparazione e supporti per il loro uso.
US5641749A (en) * 1995-11-29 1997-06-24 Amgen Inc. Method for treating retinal ganglion cell injury using glial cell line-derived neurothrophic factor (GDNF) protein product
US6063757A (en) * 1995-11-29 2000-05-16 Urso; Richard G. Wound treatment method with nerve growth factor
IT1283911B1 (it) 1996-02-05 1998-05-07 Farmigea Spa Soluzioni oftalmiche viscosizzate con polisaccaridi della gomma di tamarindo

Also Published As

Publication number Publication date
DK0973872T3 (da) 2001-11-05
US20030096413A1 (en) 2003-05-22
AU5135098A (en) 1998-11-13
CA2287780A1 (en) 1998-10-29
DE69705643T2 (de) 2002-05-29
EP0973872A1 (en) 2000-01-26
EA002986B1 (ru) 2002-12-26
JP2002507190A (ja) 2002-03-05
GR3036859T3 (en) 2002-01-31
JP3973697B2 (ja) 2007-09-12
WO1998048002A1 (en) 1998-10-29
US7429483B2 (en) 2008-09-30
IL132473A0 (en) 2001-03-19
CA2287780C (en) 2010-01-05
ITRM970238A1 (it) 1998-10-24
DE69705643D1 (de) 2001-08-16
EA199900968A1 (ru) 2000-06-26
IT1291892B1 (it) 1999-01-21
US20020037584A1 (en) 2002-03-28
ATE203054T1 (de) 2001-07-15
EP0973872B1 (en) 2001-07-11
ITRM970238A0 (it) 1997-04-24
US6537808B2 (en) 2003-03-25
PT973872E (pt) 2002-01-30
AU734801B2 (en) 2001-06-21

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