CA2288631A1 - Utilisation de principes actifs a effet biologique pour influer sur l'espace extracellulaire de cellules sensorielles et procede de commande d'administration de principe actif et dispositif approprie - Google Patents
Utilisation de principes actifs a effet biologique pour influer sur l'espace extracellulaire de cellules sensorielles et procede de commande d'administration de principe actif et dispositif approprie Download PDFInfo
- Publication number
- CA2288631A1 CA2288631A1 CA002288631A CA2288631A CA2288631A1 CA 2288631 A1 CA2288631 A1 CA 2288631A1 CA 002288631 A CA002288631 A CA 002288631A CA 2288631 A CA2288631 A CA 2288631A CA 2288631 A1 CA2288631 A1 CA 2288631A1
- Authority
- CA
- Canada
- Prior art keywords
- cells
- active substance
- sensory
- space
- calcium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
- G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
L'invention concerne l'utilisation d'un principe actif influant sur l'homéostasie du calcium de cellules pour traiter les dégénérescences de cellules sensorielles et de cellules adjacentes.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19718826.5 | 1997-05-05 | ||
DE1997118826 DE19718826A1 (de) | 1997-05-05 | 1997-05-05 | Verwendung biologisch aktiver Wirkstoffe zum Beeinflussen des Extrazellulär-Raumes von Sinneszellen und Verfahren zur Wirkstoff-Administrationssteuerung |
PCT/EP1998/001951 WO1998050065A2 (fr) | 1997-05-05 | 1998-04-02 | Utilisation de principes actifs a effet biologique pour influer sur l'espace extracellulaire de cellules sensorielles et procede de commande d'administration de principe actif et dispositif approprie |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2288631A1 true CA2288631A1 (fr) | 1998-11-12 |
Family
ID=7828596
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002288631A Abandoned CA2288631A1 (fr) | 1997-05-05 | 1998-04-02 | Utilisation de principes actifs a effet biologique pour influer sur l'espace extracellulaire de cellules sensorielles et procede de commande d'administration de principe actif et dispositif approprie |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0980256A2 (fr) |
AU (1) | AU7641798A (fr) |
CA (1) | CA2288631A1 (fr) |
DE (1) | DE19718826A1 (fr) |
WO (1) | WO1998050065A2 (fr) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2001259775B2 (en) * | 2000-05-12 | 2006-07-13 | Inspire Pharmaceuticals, Inc. | Method for treating retinal degeneration with purinergic receptor agonists |
WO2020036658A3 (fr) * | 2018-04-27 | 2020-04-02 | The Johns Hopkins University | Médicaments favorisant la survie des photorécepteurs du bâtonnet rétinien |
US11040019B2 (en) | 2016-08-19 | 2021-06-22 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Selective estrogen-receptor modulators (SERMs) confer protection against photoreceptor degeneration |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2322854A1 (fr) | 1998-03-05 | 1999-09-10 | Jun Inoue | Composition pharmaceutique pour la prophylaxie et la therapie de maladies associees a des modifications cytopathiques des tissus du fond de l'oeil |
FR2784030B1 (fr) * | 1998-10-02 | 2002-12-20 | Inst Nat Sante Rech Med | Utilisation de bloqueurs des canaux calciques et/ou cgmp-dependants pour le traitement de pathologies de la retine |
ATE446948T1 (de) * | 2003-12-12 | 2009-11-15 | Senju Pharma Co | Alpha-ketoamidderivativ, herstellungsverfahren und verwendung davon |
JP4758641B2 (ja) * | 2003-12-12 | 2011-08-31 | 千寿製薬株式会社 | α−ケトアミド誘導体、その製造方法、及びその用途 |
DE102009056597A1 (de) * | 2009-12-02 | 2011-06-09 | Tobias Brockmann | Verwendung von Flavin-Derivaten zur Behandlung von Pathologien an der Membrana limitans interna (ILM) |
Family Cites Families (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3995057A (en) * | 1974-04-19 | 1976-11-30 | Wilhelm Horrmann | Ophthalmological method |
US4188394A (en) * | 1978-05-08 | 1980-02-12 | Nelson Research & Development Company | Ophthalmic composition and method of use |
SU1297862A1 (ru) * | 1980-07-03 | 1987-03-23 | Институт цитологии и генетики СО АН СССР | Средства дл лечени пигментной дегенерации сетчатки |
JPS5718609A (en) * | 1980-07-08 | 1982-01-30 | Senjiyu Seiyaku Kk | Intraocular hypotensor |
JPS5732229A (en) * | 1980-08-05 | 1982-02-20 | Eiji Sakata | Preventing agent against kinesia |
JPS57130923A (en) * | 1981-02-07 | 1982-08-13 | Eiji Sakata | Remedy and preventive for vertigo |
CH658595A5 (de) * | 1983-08-17 | 1986-11-28 | Inst Khim Fiz An Sssr | Retinoprotektor zur behandlung von augenerkrankungen. |
US5210076A (en) * | 1988-09-13 | 1993-05-11 | Berliner David L | Methods of treating Parkinson's disease using melanin |
WO1990006118A1 (fr) * | 1988-12-05 | 1990-06-14 | Houston Biotechnology Incorporated | Utilisation therapeutique de dihydropyrimidones et de derives de benzazepine et de benzothiazepine dans le disfonctionnement du nerf optique ou retinien |
US5098443A (en) * | 1989-03-23 | 1992-03-24 | University Of Miami | Method of implanting intraocular and intraorbital implantable devices for the controlled release of pharmacological agents |
US5260059A (en) * | 1989-04-14 | 1993-11-09 | The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon Health Sciences University | Treatment of open-angle glaucoma by modulation matrix metalloproteinases and their inhibitor |
US5156852A (en) * | 1989-04-20 | 1992-10-20 | La Haye Laboratories, Inc. | Composition and method for combating macular degeneration |
US5164188A (en) * | 1989-11-22 | 1992-11-17 | Visionex, Inc. | Biodegradable ocular implants |
JPH04178328A (ja) * | 1990-11-08 | 1992-06-25 | Unitika Ltd | 血管新生阻害剤 |
JPH04182432A (ja) * | 1990-11-19 | 1992-06-30 | Toshio Tanaka | カルシウム依存性環状ヌクレオチドホスホジエステラーゼ阻害剤 |
WO1993010798A1 (fr) * | 1991-12-04 | 1993-06-10 | Uab Research Foundation | Anticorps monoclonal dirige contre la molecule d'adhesion des cellules gliales et procede d'utilisation |
US5252568A (en) * | 1992-01-24 | 1993-10-12 | Texas A&M University System | Treatment of low pressure glaucoma and ischemic retinal degeneration with loxapine |
US5266580A (en) * | 1992-01-24 | 1993-11-30 | Texas A&M University System | Treatment of low pressure glaucoma and ischemic retinal degeneration with droperidol |
EP0671879B1 (fr) * | 1992-02-14 | 2000-05-24 | Regeneron Pharmaceuticals, Inc. | Prevention des lesions et de la degenerescence des photorecepteurs par des facteurs neurotrophiques |
CN1077092A (zh) * | 1992-04-10 | 1993-10-13 | 张勇 | 一种眼保健饮料的制备方法 |
CN1082896A (zh) * | 1992-07-18 | 1994-03-02 | 苏州第六制药厂 | 止晕栓制备方法 |
JPH06234645A (ja) * | 1993-02-09 | 1994-08-23 | Toagosei Chem Ind Co Ltd | 血管新生阻害剤 |
SE9301422D0 (sv) * | 1993-04-28 | 1993-04-28 | Kabi Pharmacia Ab | Method and means for inhibiting posterior capsule opacification |
US5421818A (en) * | 1993-10-18 | 1995-06-06 | Inner Ear Medical Delivery Systems, Inc. | Multi-functional inner ear treatment and diagnostic system |
US5424321A (en) * | 1993-12-08 | 1995-06-13 | Alcon Laboratories, Inc. | Compounds having both potent calcium antagonist and antioxidant activity and use thereof as cytoprotective agents |
PT682664E (pt) * | 1993-12-08 | 2001-06-29 | Alcon Laboratoires Inc | Compostos possuindo actividade potente como antagonistas do calcio e anti-oxidantes e sua utilizacao como agentes citoprotectores |
JP2759050B2 (ja) * | 1994-01-27 | 1998-05-28 | 住友製薬株式会社 | 突発性難聴治療用医薬組成物 |
CN1057444C (zh) * | 1994-03-16 | 2000-10-18 | 吴生武 | 治疗近视眼药水 |
WO1995034302A2 (fr) * | 1994-06-16 | 1995-12-21 | Allergan | Procede utile pour reduire la pression intraoculaire dans l'×il mammalien a l'aide de composes chelatant le calcium |
EP0785196B1 (fr) * | 1995-03-28 | 2000-06-21 | Ferrer Internacional, S.A. | Polymorphes a et b de 1-(diphenylmethyl)-4-[3-(2-phenyle-1,3-dioxolan-2-yle)propyle]piperazine |
JPH11505239A (ja) * | 1995-05-19 | 1999-05-18 | ユニバーシティ オブ イースト アングリア | カルシウム細胞内貯蔵不活性化剤及びその処方物の細胞成長抑制剤としての使用方法 |
EP0840614A1 (fr) * | 1995-06-13 | 1998-05-13 | Sanofi Winthrop, Inc. | Inhibiteurs de la calpaine destines au traitement de maladies neurodegeneratives |
ATE230389T1 (de) * | 1995-10-25 | 2003-01-15 | Senju Pharma Co | Angiogenese inhibitoren |
US6423694B1 (en) * | 1996-02-21 | 2002-07-23 | Inspire Pharmaceuticals, Inc. | Method of treating otitis media with uridine triphosphates and related compounds |
US5904144A (en) * | 1996-03-22 | 1999-05-18 | Cytotherapeutics, Inc. | Method for treating ophthalmic diseases |
IT1290801B1 (it) * | 1996-07-05 | 1998-12-11 | Mendes Srl | Uso della acetil l-carnitina, della isovaleril l-carnitina, della propionil l-carnitina o dei loro sali farmacologicamente accettabili |
US6303579B1 (en) * | 1996-10-31 | 2001-10-16 | Alcon Laboratories, Inc. | Use of calpain inhibitors to treat ocular neural pathology |
IT1288399B1 (it) * | 1996-12-03 | 1998-09-22 | Sigma Tau Ind Farmaceuti | Medicamento per il trattamento terapeutico della maculopatia legata all'eta', della maculopatia non legata all'eta' e per la profilassi |
-
1997
- 1997-05-05 DE DE1997118826 patent/DE19718826A1/de not_active Withdrawn
-
1998
- 1998-04-02 CA CA002288631A patent/CA2288631A1/fr not_active Abandoned
- 1998-04-02 EP EP98924097A patent/EP0980256A2/fr not_active Withdrawn
- 1998-04-02 WO PCT/EP1998/001951 patent/WO1998050065A2/fr not_active Application Discontinuation
- 1998-04-02 AU AU76417/98A patent/AU7641798A/en not_active Abandoned
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2001259775B2 (en) * | 2000-05-12 | 2006-07-13 | Inspire Pharmaceuticals, Inc. | Method for treating retinal degeneration with purinergic receptor agonists |
US11040019B2 (en) | 2016-08-19 | 2021-06-22 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Selective estrogen-receptor modulators (SERMs) confer protection against photoreceptor degeneration |
WO2020036658A3 (fr) * | 2018-04-27 | 2020-04-02 | The Johns Hopkins University | Médicaments favorisant la survie des photorécepteurs du bâtonnet rétinien |
Also Published As
Publication number | Publication date |
---|---|
WO1998050065A2 (fr) | 1998-11-12 |
EP0980256A2 (fr) | 2000-02-23 |
WO1998050065A3 (fr) | 1999-06-10 |
DE19718826A1 (de) | 1998-11-12 |
AU7641798A (en) | 1998-11-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
FZDE | Discontinued | ||
FZDE | Discontinued |
Effective date: 20040402 |