CA2240963C - Process for producing l-threonine by culturing escherichia coli - Google Patents

Process for producing l-threonine by culturing escherichia coli Download PDF

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Publication number
CA2240963C
CA2240963C CA2240963A CA2240963A CA2240963C CA 2240963 C CA2240963 C CA 2240963C CA 2240963 A CA2240963 A CA 2240963A CA 2240963 A CA2240963 A CA 2240963A CA 2240963 C CA2240963 C CA 2240963C
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CA
Canada
Prior art keywords
threonine
amino acid
producing
escherichia coli
medium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA2240963A
Other languages
English (en)
French (fr)
Other versions
CA2240963A1 (en
Inventor
Kazuyuki Okamoto
Masato Ikeda
Kuniki Kino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyowa Hakko Bio Co Ltd
Original Assignee
Kyowa Hakko Bio Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Bio Co Ltd filed Critical Kyowa Hakko Bio Co Ltd
Publication of CA2240963A1 publication Critical patent/CA2240963A1/en
Application granted granted Critical
Publication of CA2240963C publication Critical patent/CA2240963C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/848—Escherichia
    • Y10S435/849—Escherichia coli

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA2240963A 1997-06-23 1998-06-18 Process for producing l-threonine by culturing escherichia coli Expired - Lifetime CA2240963C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP16571697A JP3966583B2 (ja) 1997-06-23 1997-06-23 発酵法によるｌ−アミノ酸の製造法
JP165716/97 1997-06-23

Publications (2)

Publication Number Publication Date
CA2240963A1 CA2240963A1 (en) 1998-12-23
CA2240963C true CA2240963C (en) 2014-07-08

Family

ID=15817716

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2240963A Expired - Lifetime CA2240963C (en) 1997-06-23 1998-06-18 Process for producing l-threonine by culturing escherichia coli

Country Status (7)

Country Link
US (2) US5919670A (https=)
EP (1) EP0887420B1 (https=)
JP (1) JP3966583B2 (https=)
AT (1) ATE317911T1 (https=)
CA (1) CA2240963C (https=)
DE (1) DE69833469T2 (https=)
HU (1) HU225737B1 (https=)

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US6451564B1 (en) 1999-07-02 2002-09-17 Massachusetts Institute Of Technology Methods for producing L-isoleucine
DE19941478A1 (de) 1999-09-01 2001-03-08 Degussa Neue für das thrE-Gen codierende Nukleotidsequenzen und Verfahren zur fermentativen Herstellung von L-Threonin mit coryneformen Bakterien
US6927046B1 (en) * 1999-12-30 2005-08-09 Archer-Daniels-Midland Company Increased lysine production by gene amplification using coryneform bacteria
DE10046934A1 (de) * 2000-09-21 2002-04-18 Consortium Elektrochem Ind Verfahren zur fermentativen Herstellung von nicht-proteinogenen L-Aminosäuren
KR100397321B1 (ko) * 2000-12-26 2003-09-06 씨제이 주식회사 5'-이노신산을 고수율로 생산하는 미생물 코리네박테리움암모니아게네스 씨제이아이피009 및 그를 이용한5'-이노신산 생산방법
JP2002209596A (ja) * 2001-01-19 2002-07-30 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
EP2426142A3 (en) * 2006-10-16 2012-06-13 Genelux Corporation Modified vaccinia virus strains for use in a diagnostic and therapeutic method
WO2008150496A2 (en) * 2007-05-31 2008-12-11 Genelux Corporation Assay for sensitivity to chemotherapeutic agents
JP5213075B2 (ja) 2007-06-15 2013-06-19 ジェネラックス・コーポレイション 腫瘍の画像化および／または処置のための微生物
JP5504514B2 (ja) * 2009-02-11 2014-05-28 国立大学法人島根大学 Ｌ−アスパラギン酸製造方法
WO2013138522A2 (en) 2012-03-16 2013-09-19 Genelux Corporation Methods for assessing effectiveness and monitoring oncolytic virus treatment
WO2013158265A1 (en) 2012-04-20 2013-10-24 Genelux Corporation Imaging methods for oncolytic virus therapy
US10167490B2 (en) 2012-12-21 2019-01-01 Ergo Health Llc Ergothioneine production through metabolic engineering
EP2978446B1 (en) 2013-03-27 2020-03-04 The General Hospital Corporation Anti-cd33 antibody for use in treating alzheimer's disease
EP3083658B1 (en) 2013-12-18 2019-05-08 President and Fellows of Harvard College Crp capture/detection of gram positive bacteria
US10435457B2 (en) 2015-08-06 2019-10-08 President And Fellows Of Harvard College Microbe-binding molecules and uses thereof
WO2018049261A1 (en) 2016-09-09 2018-03-15 Icellhealth Consulting Llc Oncolytic virus expressing immune checkpoint modulators
EP3357352B1 (de) 2017-02-02 2021-03-24 artgerecht GmbH Zusammensetzung mit aminosäuren
DE102017201713A1 (de) 2017-02-02 2018-08-02 artgerecht GmbH Zusammensetzung mit Aminosäuren
JP7303743B2 (ja) 2017-04-05 2023-07-05 アスガード セラピューティクス エービー 細胞を樹状細胞または抗原提示細胞にリプログラムするための組成物、その方法および使用
EP3385373A1 (en) 2017-04-05 2018-10-10 Centro de Neurociências e Biologia Celular Compositions for reprogramming cells into dendritic cells or antigen presenting cells, methods and uses thereof
KR101947945B1 (ko) * 2018-01-25 2019-02-13 씨제이제일제당 (주) L-아미노산을 생산하는 코리네박테리움 속 미생물 및 이를 이용한 l-아미노산의 생산방법
EP3876966A4 (en) 2018-11-09 2022-07-27 The Children's Medical Center Corporation METHODS AND COMPOSITIONS FOR THE TREATMENT OR PREVENTION OF THE DEVELOPMENT OF FOOD ALLERGIES
US20220152098A1 (en) 2019-03-01 2022-05-19 Achelois Biopharma, Inc. Methods of modulating cd160 function in the antigen-specific immune cell and uses thereof
CN117062611A (zh) 2021-01-26 2023-11-14 惠和生物技术(上海)有限公司 嵌合抗原受体（car）构建体和表达car构建体的nk细胞
WO2025232879A1 (en) 2024-05-10 2025-11-13 Cytocares (Shanghai) Inc. Anti-lilrb2 monospecific and bispecific antibody constructs and uses thereof

Family Cites Families (19)

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JPS5031093A (https=) * 1973-07-26 1975-03-27
DE2545623C3 (de) * 1975-10-11 1979-11-08 Loos & Schmidt Wilhelm Loos Gmbh, 5970 Plettenberg Gewindeschneidautomat für Muttern o.a. Massenformteile
JPS6051338B2 (ja) * 1979-06-30 1985-11-13 株式会社東芝 電力調整装置
JPS56134993A (en) * 1980-03-21 1981-10-22 Tanabe Seiyaku Co Ltd Preparation of l-threonine by fermentation method
JPS58893A (ja) * 1981-06-25 1983-01-06 Ajinomoto Co Inc 発酵法によるｌ−イソロイシンの製造法
JPH0732711B2 (ja) * 1983-07-29 1995-04-12 協和醗酵工業株式会社 Ｌ−イソロイシンの製造法
US4601983A (en) * 1983-06-15 1986-07-22 Ajinomoto Co., Inc. Coryneform bacteria carrying recombinant plasmids and their use in the fermentative production of L-threonine and L-isoleucine
JPS6066984A (ja) * 1983-09-22 1985-04-17 Ajinomoto Co Inc 発酵法によるｌ−フェニルアラニンの製造法
JPS61195695A (ja) * 1985-02-26 1986-08-29 Ajinomoto Co Inc スレオニン又はイソロイシンの製造法
US5264353A (en) * 1985-08-23 1993-11-23 Toray Industries, Inc. Process for producing L-threonine by fermentation
JPS6244193A (ja) * 1985-08-23 1987-02-26 Toray Ind Inc 発酵法によるｌ−スレオニンの製造方法
JP2574786B2 (ja) * 1986-02-20 1997-01-22 協和醗酵工業株式会社 Ｌ−スレオニンの製造法
US5017483A (en) * 1986-02-20 1991-05-21 Kyowa Hakko Kogyo Co., Ltd. Process for producing L-threonine
JPS6437295A (en) * 1987-07-31 1989-02-07 Kyowa Hakko Kogyo Kk Production of l-threonine by fermentation
JP2536570B2 (ja) * 1987-10-12 1996-09-18 味の素株式会社 発酵法によるｌ―イソロイシンの製造法
JP2748418B2 (ja) * 1988-08-03 1998-05-06 味の素株式会社 組換えｄｎａ、該組換えｄｎａを有する微生物
JP3237134B2 (ja) * 1991-04-30 2001-12-10 味の素株式会社 アミノ酸生産能を有する微生物及び当該微生物を用いるアミノ酸の製造法
EP0519113A1 (en) * 1991-06-21 1992-12-23 Ajinomoto Co., Inc. Bacterial strains having high productivity of an amino acid and method of constructing these strains
JP3006926B2 (ja) * 1991-09-04 2000-02-07 協和醗酵工業株式会社 発酵法によるｌ−スレオニンの製造法

Also Published As

Publication number Publication date
US6143552A (en) 2000-11-07
EP0887420A3 (en) 2001-11-21
ATE317911T1 (de) 2006-03-15
JPH119295A (ja) 1999-01-19
DE69833469D1 (de) 2006-04-20
CA2240963A1 (en) 1998-12-23
US5919670A (en) 1999-07-06
HUP9801420A2 (hu) 1999-06-28
EP0887420A2 (en) 1998-12-30
EP0887420B1 (en) 2006-02-15
HUP9801420A3 (en) 2003-07-28
DE69833469T2 (de) 2006-11-09
HU225737B1 (en) 2007-07-30
HU9801420D0 (en) 1998-08-28
JP3966583B2 (ja) 2007-08-29

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