CA2234071C - Intensive homologous promoter obtained from hamsters - Google Patents
Intensive homologous promoter obtained from hamsters Download PDFInfo
- Publication number
- CA2234071C CA2234071C CA002234071A CA2234071A CA2234071C CA 2234071 C CA2234071 C CA 2234071C CA 002234071 A CA002234071 A CA 002234071A CA 2234071 A CA2234071 A CA 2234071A CA 2234071 C CA2234071 C CA 2234071C
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- promoter
- nucleic acid
- gene
- acid molecule
- sequence
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- 210000003705 ribosome Anatomy 0.000 description 1
- 230000028706 ribosome biogenesis Effects 0.000 description 1
- IOVGROKTTNBUGK-SJCJKPOMSA-N ritodrine Chemical compound N([C@@H](C)[C@H](O)C=1C=CC(O)=CC=1)CCC1=CC=C(O)C=C1 IOVGROKTTNBUGK-SJCJKPOMSA-N 0.000 description 1
- 238000005185 salting out Methods 0.000 description 1
- 230000035939 shock Effects 0.000 description 1
- 210000001812 small ribosome subunit Anatomy 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 230000010473 stable expression Effects 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000004114 suspension culture Methods 0.000 description 1
- 229940037128 systemic glucocorticoids Drugs 0.000 description 1
- 108010061238 threonyl-glycine Proteins 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 238000013519 translation Methods 0.000 description 1
- 230000014621 translational initiation Effects 0.000 description 1
- 229960001727 tretinoin Drugs 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
- C12N2830/85—Vector systems having a special element relevant for transcription from vertebrates mammalian
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19539493.3 | 1995-10-24 | ||
| DE19539493A DE19539493A1 (de) | 1995-10-24 | 1995-10-24 | Starker homologer Promotor aus Hamster |
| PCT/EP1996/004631 WO1997015664A1 (de) | 1995-10-24 | 1996-10-24 | Starker homologer promotor aus hamster |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2234071A1 CA2234071A1 (en) | 1997-05-01 |
| CA2234071C true CA2234071C (en) | 2003-01-21 |
Family
ID=7775593
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002234071A Expired - Lifetime CA2234071C (en) | 1995-10-24 | 1996-10-24 | Intensive homologous promoter obtained from hamsters |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6063598A (enExample) |
| EP (2) | EP1803815A3 (enExample) |
| JP (2) | JP3966903B2 (enExample) |
| AT (1) | ATE355370T1 (enExample) |
| CA (1) | CA2234071C (enExample) |
| DE (2) | DE19539493A1 (enExample) |
| DK (1) | DK0857211T3 (enExample) |
| ES (1) | ES2281905T3 (enExample) |
| MX (1) | MX9802764A (enExample) |
| PT (1) | PT857211E (enExample) |
| WO (1) | WO1997015664A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7833787B2 (en) | 2003-08-19 | 2010-11-16 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Method for recloning Chinese hamster ovary (CHO) cells |
Families Citing this family (91)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0961830A1 (en) * | 1997-01-29 | 1999-12-08 | Neurosearch A/S | EXPRESSION VECTORS AND METHODS FOR $i(IN VIVO) EXPRESSION OF THERAPEUTIC POLYPEPTIDES |
| EP1624067A3 (en) * | 2000-09-18 | 2006-03-15 | Genzyme Corporation | Expression vectors containing hybrid ubiquitin promoters |
| DE60115070T2 (de) * | 2000-09-18 | 2006-07-27 | Genzyme Corp., Cambridge | Expressionsvektoren mit hybriden ubiquitin-promotoren |
| ATE466943T1 (de) * | 2001-07-04 | 2010-05-15 | Chromagenics Bv | Dns-sequenzen mit anti-repressor aktivität |
| DE10256083A1 (de) | 2002-11-29 | 2004-08-12 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Expressionsvektor, Verfahren zur Herstellung von heterologen Genprodukten und Selektionsverfahren für hochproduzierende rekombinante Zellen |
| US7384744B2 (en) | 2002-11-29 | 2008-06-10 | Boehringer Ingelheim Pharma Gmbh & Co., Kg | Expression vector, methods for the production of heterologous gene products and for the selection of recombinant cells producing high levels of such products |
| US7344886B2 (en) | 2002-11-29 | 2008-03-18 | Boehringer Ingelheim Pharma Gmbh & Co., Kg | Neomycin-phosphotransferase-genes and methods for the selection of recombinant cells producing high levels of a desired gene product |
| US8669109B2 (en) | 2003-08-19 | 2014-03-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Methods of producing proteins in Chinese hamster ovary (CHO) cells |
| US20050101017A1 (en) * | 2003-11-10 | 2005-05-12 | Wojtek Auerbach | Method of improving gene targeting using a ubiquitin promoter |
| GB0509965D0 (en) * | 2005-05-17 | 2005-06-22 | Ml Lab Plc | Improved expression elements |
| AU2006277568B2 (en) * | 2005-06-20 | 2011-06-30 | Cadila Healthcare Limited | Expression vector and methods of producing high levels of proteins |
| EP1806365A1 (en) | 2006-01-05 | 2007-07-11 | Boehringer Ingelheim International GmbH | Antibody molecules specific for fibroblast activation protein and immunoconjugates containing them |
| US20080124760A1 (en) * | 2006-07-26 | 2008-05-29 | Barbara Enenkel | Regulatory Nucleic Acid Elements |
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-
1995
- 1995-10-24 DE DE19539493A patent/DE19539493A1/de not_active Ceased
-
1996
- 1996-10-24 US US09/051,969 patent/US6063598A/en not_active Expired - Lifetime
- 1996-10-24 DK DK96937224T patent/DK0857211T3/da active
- 1996-10-24 EP EP06126019A patent/EP1803815A3/de not_active Withdrawn
- 1996-10-24 DE DE59611420T patent/DE59611420D1/de not_active Expired - Lifetime
- 1996-10-24 AT AT96937224T patent/ATE355370T1/de active
- 1996-10-24 WO PCT/EP1996/004631 patent/WO1997015664A1/de not_active Ceased
- 1996-10-24 JP JP51628897A patent/JP3966903B2/ja not_active Expired - Lifetime
- 1996-10-24 EP EP96937224A patent/EP0857211B1/de not_active Expired - Lifetime
- 1996-10-24 CA CA002234071A patent/CA2234071C/en not_active Expired - Lifetime
- 1996-10-24 ES ES96937224T patent/ES2281905T3/es not_active Expired - Lifetime
- 1996-10-24 PT PT96937224T patent/PT857211E/pt unknown
-
1998
- 1998-04-07 MX MX9802764A patent/MX9802764A/es active IP Right Grant
-
2006
- 2006-07-07 JP JP2006187719A patent/JP2006320330A/ja active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7833787B2 (en) | 2003-08-19 | 2010-11-16 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Method for recloning Chinese hamster ovary (CHO) cells |
Also Published As
| Publication number | Publication date |
|---|---|
| DE59611420D1 (de) | 2007-04-12 |
| EP0857211A1 (de) | 1998-08-12 |
| DE19539493A1 (de) | 1997-04-30 |
| MX9802764A (es) | 1998-11-30 |
| WO1997015664A1 (de) | 1997-05-01 |
| JP2006320330A (ja) | 2006-11-30 |
| JP3966903B2 (ja) | 2007-08-29 |
| PT857211E (pt) | 2007-03-30 |
| CA2234071A1 (en) | 1997-05-01 |
| EP1803815A2 (de) | 2007-07-04 |
| US6063598A (en) | 2000-05-16 |
| ATE355370T1 (de) | 2006-03-15 |
| EP1803815A3 (de) | 2007-08-29 |
| DK0857211T3 (da) | 2007-03-26 |
| EP0857211B1 (de) | 2007-02-28 |
| ES2281905T3 (es) | 2007-10-01 |
| JPH11513572A (ja) | 1999-11-24 |
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