CA2230556C - Novel procollagens - Google Patents

Novel procollagens Download PDF

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Publication number
CA2230556C
CA2230556C CA2230556A CA2230556A CA2230556C CA 2230556 C CA2230556 C CA 2230556C CA 2230556 A CA2230556 A CA 2230556A CA 2230556 A CA2230556 A CA 2230556A CA 2230556 C CA2230556 C CA 2230556C
Authority
CA
Canada
Prior art keywords
pro
gly
alpha
collagen
ala
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2230556A
Other languages
English (en)
French (fr)
Other versions
CA2230556A1 (en
Inventor
Neil Bulleid
Karl Kadler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Victoria University of Manchester
University of Manchester
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9517773.9A external-priority patent/GB9517773D0/en
Priority claimed from GBGB9606152.8A external-priority patent/GB9606152D0/en
Priority claimed from GBGB9612476.3A external-priority patent/GB9612476D0/en
Application filed by Victoria University of Manchester, University of Manchester filed Critical Victoria University of Manchester
Publication of CA2230556A1 publication Critical patent/CA2230556A1/en
Application granted granted Critical
Publication of CA2230556C publication Critical patent/CA2230556C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • G—PHYSICS
    • G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03C—PHOTOSENSITIVE MATERIALS FOR PHOTOGRAPHIC PURPOSES; PHOTOGRAPHIC PROCESSES, e.g. CINE, X-RAY, COLOUR, STEREO-PHOTOGRAPHIC PROCESSES; AUXILIARY PROCESSES IN PHOTOGRAPHY
    • G03C1/00—Photosensitive materials
    • G03C1/005—Silver halide emulsions; Preparation thereof; Physical treatment thereof; Incorporation of additives therein
    • G03C1/04—Silver halide emulsions; Preparation thereof; Physical treatment thereof; Incorporation of additives therein with macromolecular additives; with layer-forming substances
    • G03C1/047—Proteins, e.g. gelatine derivatives; Hydrolysis or extraction products of proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Investigating Or Analyzing Materials Using Thermal Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Body Structure For Vehicles (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
CA2230556A 1995-08-31 1996-08-30 Novel procollagens Expired - Fee Related CA2230556C (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GB9517773.9 1995-08-31
GBGB9517773.9A GB9517773D0 (en) 1995-08-31 1995-08-31 Novel procollagens
GB9606152.8 1996-03-23
GBGB9606152.8A GB9606152D0 (en) 1996-03-23 1996-03-23 Novel procollagens
GBGB9612476.3A GB9612476D0 (en) 1996-06-14 1996-06-14 Novel procollagens
GB9612476.3 1996-06-14
PCT/GB1996/002122 WO1997008311A1 (en) 1995-08-31 1996-08-30 Novel procollagens

Publications (2)

Publication Number Publication Date
CA2230556A1 CA2230556A1 (en) 1997-03-06
CA2230556C true CA2230556C (en) 2011-06-07

Family

ID=27267880

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2230556A Expired - Fee Related CA2230556C (en) 1995-08-31 1996-08-30 Novel procollagens

Country Status (11)

Country Link
US (1) US6171827B1 (https=)
EP (1) EP0859838B1 (https=)
JP (1) JP4003836B2 (https=)
AT (1) ATE242325T1 (https=)
AU (1) AU724706B2 (https=)
CA (1) CA2230556C (https=)
DE (1) DE69628576T2 (https=)
DK (1) DK0859838T3 (https=)
ES (1) ES2201193T3 (https=)
PT (1) PT859838E (https=)
WO (1) WO1997008311A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11377490B2 (en) 2017-05-31 2022-07-05 Sichuan Clover Biopharmaceuticals, Inc Method for treating cancer using disulfide-linked trimeric 4-1BBL

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5266683A (en) * 1988-04-08 1993-11-30 Stryker Corporation Osteogenic proteins
US20070166353A1 (en) * 1988-04-08 2007-07-19 Stryker Corporation Osteogenic proteins
US6919308B2 (en) * 1988-04-08 2005-07-19 Stryker Corporation Osteogenic devices
US6586388B2 (en) 1988-04-08 2003-07-01 Stryker Corporation Method of using recombinant osteogenic protein to repair bone or cartilage defects
US20080233170A1 (en) * 1992-02-21 2008-09-25 Stryker Corporation Osteogenic Proteins
GB9704305D0 (en) * 1997-03-01 1997-04-23 Univ Manchester Procollagen assembly
US6022694A (en) * 1997-04-04 2000-02-08 Regeneron Pharmaceuticals, Inc. Assay for ligands to tyrosine kinase receptors
EP0913692A1 (en) * 1997-10-31 1999-05-06 Bayer Ag An immunoassay for procollagen-III-C-terminal propeptide
US6428978B1 (en) 1998-05-08 2002-08-06 Cohesion Technologies, Inc. Methods for the production of gelatin and full-length triple helical collagen in recombinant cells
JP2000125872A (ja) * 1998-09-07 2000-05-09 Terumo Corp 三量体キメラタンパク質およびキメラタンパク質を含有するコラーゲンマトリックス
DE10053870A1 (de) * 2000-10-31 2002-05-08 Burchardt Elmar Reinhold Procollagen (III)-Propeptide und verwandte Substanzen zur Behandlung von fibrotischen Erkrankungen
CN1196712C (zh) * 2001-02-21 2005-04-13 范代娣 一种类人胶原蛋白及其生产方法
GB0309064D0 (en) * 2003-04-22 2003-05-28 Univ Manchester Modified peptides and their uses
US7268116B2 (en) * 2003-10-02 2007-09-11 Genhunter Corp. Methods and compositions for producing secreted trimeric receptor analogs and biologically active fusion proteins
US9095569B2 (en) * 2008-04-18 2015-08-04 Collplant Ltd. Methods of generating and using procollagen
CN101601858B (zh) 2009-05-27 2012-09-19 上海交通大学 中期因子蛋白的用途及含该蛋白的医用装置
US9725498B2 (en) 2009-07-17 2017-08-08 The Texas A&M University System Designer collagens and use thereof
EP2454367B1 (en) * 2009-07-17 2013-10-16 The Texas A&M University System Designer collagens and uses thereof
WO2013072504A1 (en) * 2011-11-16 2013-05-23 Centre National De La Recherche Scientifique (Cnrs) Crystal structure of the procollagen iii c-propeptide trimer and applications thereof
CN104884468B (zh) * 2012-12-28 2018-08-31 国立大学法人大阪大学 附加有胶原结合性分子的改造层粘连蛋白及其利用
WO2019098246A1 (ja) * 2017-11-14 2019-05-23 国立大学法人筑波大学 改変されたコラーゲンタンパク質およびその用途
WO2021249116A1 (en) 2020-06-10 2021-12-16 Sichuan Clover Biopharmaceuticals, Inc. Coronavirus vaccine compositions, methods, and uses thereof
WO2021249011A1 (en) 2020-06-10 2021-12-16 Sichuan Clover Biopharmaceuticals, Inc. Hiv vaccine compositions, methods, and uses thereof
WO2022041760A1 (en) 2020-08-31 2022-03-03 Sichuan Clover Biopharmaceuticals, Inc. Methods and compositions for purification of trimeric fusion proteins
CN116813749B (zh) * 2023-06-13 2024-01-30 广州启点生物科技有限公司 一种重组人源化iii型胶原蛋白及其制备方法和应用
EP4711378A1 (en) * 2024-09-12 2026-03-18 AcroPharma AB Peptide agonists of gpr56

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU84485A1 (fr) 1982-11-22 1984-06-13 Oreal Nouvelle composition anti-acneique a base de peroxyde de benzoyle et d'au moins un autre principe actif
GB9014220D0 (en) 1990-06-26 1990-08-15 Farmos Yhtymy Oy Method for the immunlolgical determinition of the carboxyterminal propeptide of type i procollagen
US5424408A (en) * 1990-11-30 1995-06-13 Yale University α-3 chain type IV collagen polynucleotides
JP3302017B2 (ja) * 1991-10-23 2002-07-15 トーマス・ジェファーソン・ユニバーシティ 組み換えｄｎａ合成システムにおけるヒトプロコラーゲン及びコラーゲンの合成
US5667839A (en) * 1993-01-28 1997-09-16 Collagen Corporation Human recombinant collagen in the milk of transgenic animals

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11377490B2 (en) 2017-05-31 2022-07-05 Sichuan Clover Biopharmaceuticals, Inc Method for treating cancer using disulfide-linked trimeric 4-1BBL
US11472873B2 (en) 2017-05-31 2022-10-18 Sichuan Clover Biopharmaceuticals, Inc. Method treating malignant ascites and metastatic pleural effusion with and disulfide-linked trimeric TRAIL

Also Published As

Publication number Publication date
JP4003836B2 (ja) 2007-11-07
CA2230556A1 (en) 1997-03-06
EP0859838B1 (en) 2003-06-04
ES2201193T3 (es) 2004-03-16
AU6832696A (en) 1997-03-19
PT859838E (pt) 2003-10-31
ATE242325T1 (de) 2003-06-15
DE69628576D1 (de) 2003-07-10
WO1997008311A1 (en) 1997-03-06
JP2000506362A (ja) 2000-05-30
DE69628576T2 (de) 2004-04-22
DK0859838T3 (da) 2003-10-06
EP0859838A1 (en) 1998-08-26
US6171827B1 (en) 2001-01-09
AU724706B2 (en) 2000-09-28

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Effective date: 20140902