CA2225999C - Inhaler for administering medicaments from blister packs - Google Patents
Inhaler for administering medicaments from blister packs Download PDFInfo
- Publication number
- CA2225999C CA2225999C CA002225999A CA2225999A CA2225999C CA 2225999 C CA2225999 C CA 2225999C CA 002225999 A CA002225999 A CA 002225999A CA 2225999 A CA2225999 A CA 2225999A CA 2225999 C CA2225999 C CA 2225999C
- Authority
- CA
- Canada
- Prior art keywords
- housing
- plunger
- blister
- pressing
- inhaler
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000003814 drug Substances 0.000 title claims abstract description 45
- 239000011888 foil Substances 0.000 claims abstract description 37
- 238000003825 pressing Methods 0.000 claims abstract description 17
- 230000005540 biological transmission Effects 0.000 claims description 10
- 239000013013 elastic material Substances 0.000 claims description 2
- 230000000994 depressogenic effect Effects 0.000 claims 3
- 230000000881 depressing effect Effects 0.000 claims 1
- 238000007789 sealing Methods 0.000 claims 1
- 239000011797 cavity material Substances 0.000 description 81
- 239000000843 powder Substances 0.000 description 18
- 239000000463 material Substances 0.000 description 9
- 239000011324 bead Substances 0.000 description 7
- 210000003811 finger Anatomy 0.000 description 6
- -1 polyoxymethylene Polymers 0.000 description 5
- 229920000642 polymer Polymers 0.000 description 4
- 238000000034 method Methods 0.000 description 3
- 230000000284 resting effect Effects 0.000 description 3
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- 239000004698 Polyethylene Substances 0.000 description 2
- 239000004743 Polypropylene Substances 0.000 description 2
- XECAHXYUAAWDEL-UHFFFAOYSA-N acrylonitrile butadiene styrene Chemical compound C=CC=C.C=CC#N.C=CC1=CC=CC=C1 XECAHXYUAAWDEL-UHFFFAOYSA-N 0.000 description 2
- 239000004676 acrylonitrile butadiene styrene Substances 0.000 description 2
- 229920000122 acrylonitrile butadiene styrene Polymers 0.000 description 2
- 239000004411 aluminium Substances 0.000 description 2
- 229910052782 aluminium Inorganic materials 0.000 description 2
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 2
- 238000000071 blow moulding Methods 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 229910052751 metal Inorganic materials 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 238000004806 packaging method and process Methods 0.000 description 2
- 229920000573 polyethylene Polymers 0.000 description 2
- 229920006324 polyoxymethylene Polymers 0.000 description 2
- 229920001155 polypropylene Polymers 0.000 description 2
- 229920000915 polyvinyl chloride Polymers 0.000 description 2
- 239000004800 polyvinyl chloride Substances 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 description 1
- 229910000838 Al alloy Inorganic materials 0.000 description 1
- 241001272567 Hominoidea Species 0.000 description 1
- 229930040373 Paraformaldehyde Natural products 0.000 description 1
- 229930182556 Polyacetal Natural products 0.000 description 1
- 239000004793 Polystyrene Substances 0.000 description 1
- 208000024716 acute asthma Diseases 0.000 description 1
- 239000000443 aerosol Substances 0.000 description 1
- 229940057188 blistex Drugs 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 239000013536 elastomeric material Substances 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 150000008282 halocarbons Chemical class 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000005065 mining Methods 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 239000004926 polymethyl methacrylate Substances 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 238000003856 thermoforming Methods 0.000 description 1
- 229920001169 thermoplastic Polymers 0.000 description 1
- 239000004416 thermosoftening plastic Substances 0.000 description 1
- 210000003813 thumb Anatomy 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
- A61M15/0031—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up by bursting or breaking the package, i.e. without cutting or piercing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
- A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
- A61M15/0048—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged in a plane, e.g. on diskettes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
- A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
- A61M15/0051—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged on a tape, e.g. strips
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Veterinary Medicine (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Packages (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Control And Other Processes For Unpacking Of Materials (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Basic Packing Technique (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19523516A DE19523516C1 (de) | 1995-06-30 | 1995-06-30 | Inhalator zum Verabreichen von Medikamenten aus Blisterpackungen |
| DE19523516.9 | 1995-06-30 | ||
| PCT/EP1996/002384 WO1997002061A1 (en) | 1995-06-30 | 1996-06-01 | Inhaler for administering medicaments from blister packs |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2225999A1 CA2225999A1 (en) | 1997-01-23 |
| CA2225999C true CA2225999C (en) | 2002-08-20 |
Family
ID=7765485
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002225999A Expired - Fee Related CA2225999C (en) | 1995-06-30 | 1996-06-01 | Inhaler for administering medicaments from blister packs |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US5881719A (forum.php) |
| EP (1) | EP0835148B1 (forum.php) |
| JP (1) | JP3258025B2 (forum.php) |
| KR (1) | KR100253855B1 (forum.php) |
| CN (1) | CN1112222C (forum.php) |
| AR (1) | AR002598A1 (forum.php) |
| AT (1) | ATE205099T1 (forum.php) |
| AU (1) | AU694667B2 (forum.php) |
| BR (1) | BR9609645A (forum.php) |
| CA (1) | CA2225999C (forum.php) |
| CZ (1) | CZ286678B6 (forum.php) |
| DE (2) | DE19523516C1 (forum.php) |
| DK (1) | DK0835148T3 (forum.php) |
| ES (1) | ES2163635T3 (forum.php) |
| HR (1) | HRP960300B1 (forum.php) |
| HU (1) | HU219905B (forum.php) |
| IL (1) | IL122605A (forum.php) |
| IN (1) | IN188127B (forum.php) |
| NO (1) | NO314657B1 (forum.php) |
| NZ (1) | NZ309793A (forum.php) |
| PL (1) | PL181208B1 (forum.php) |
| PT (1) | PT835148E (forum.php) |
| RU (1) | RU2158609C2 (forum.php) |
| SI (1) | SI9620082A (forum.php) |
| SK (1) | SK282508B6 (forum.php) |
| TR (1) | TR199701732T1 (forum.php) |
| TW (1) | TW311092B (forum.php) |
| UA (1) | UA34505C2 (forum.php) |
| WO (1) | WO1997002061A1 (forum.php) |
| ZA (1) | ZA965484B (forum.php) |
Families Citing this family (159)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6290991B1 (en) | 1994-12-02 | 2001-09-18 | Quandrant Holdings Cambridge Limited | Solid dose delivery vehicle and methods of making same |
| RU2146153C1 (ru) * | 1994-09-21 | 2000-03-10 | Инхейл Терапьютик Системз | Устройство и способ распыления лекарственных средств в виде сухого порошка (варианты) |
| US20040237961A1 (en) * | 1995-06-08 | 2004-12-02 | Snow John Medlin | Inhalation actuated device for use with metered dose inhalers (MDIs) |
| US6672304B1 (en) | 1995-06-08 | 2004-01-06 | Innovative Devices, Llc | Inhalation actuated device for use with metered dose inhalers (MDIs) |
| US6209538B1 (en) * | 1995-08-02 | 2001-04-03 | Robert A. Casper | Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament |
| DE59605366D1 (de) | 1995-12-07 | 2000-07-06 | Jago Pharma Ag Muttenz | Inhalator zur mehrfachen dosisweisen abgabe eines pharmakologischen trockenpulvers |
| AU132977S (en) | 1996-05-17 | 1998-02-17 | Astrazeneca Ab | Container for inhaling apparatus |
| SE9700423D0 (sv) * | 1997-02-07 | 1997-02-07 | Astra Ab | Disposable inhaler |
| SE9700424D0 (sv) * | 1997-02-07 | 1997-02-07 | Astra Ab | Powder inhaler |
| US6237590B1 (en) * | 1997-09-18 | 2001-05-29 | Delsys Pharmaceutical Corporation | Dry powder delivery system apparatus |
| USD421800S (en) * | 1998-02-19 | 2000-03-21 | Pierre Fabre Medicament | Powder and compressed-air inhaler |
| KR100277031B1 (ko) | 1998-02-25 | 2001-01-15 | 구본준 | 중첩 변조 방법 및 장치 |
| ID26237A (id) | 1998-03-16 | 2000-12-07 | Inhale Therapeutic Syst | Pengantaran zat aktif teraerosolisasi |
| SE9800897D0 (sv) | 1998-03-17 | 1998-03-17 | Astra Ab | Inhalation device |
| PT1089783E (pt) * | 1998-06-22 | 2005-01-31 | Astrazeneca Ab | Dispositivo para esvaziar por aspiracao cavidades contendo po |
| DE19831525A1 (de) * | 1998-07-14 | 2000-01-20 | Pfeiffer Erich Gmbh & Co Kg | Spender für Medien |
| UA73924C2 (en) * | 1998-10-09 | 2005-10-17 | Nektar Therapeutics | Device for delivering active agent formulation to lungs of human patient |
| PT1129064E (pt) | 1998-11-12 | 2008-01-31 | Invitrogen Corp | Reagentes de transfecção |
| DE29908593U1 (de) | 1999-05-14 | 1999-07-22 | Jago Research AG, Hergiswil | Mundstück für einen Inhalator zur Abgabe eines Medikaments |
| ATE294608T1 (de) | 1999-06-05 | 2005-05-15 | Innovata Biomed Ltd | Verabreichungsystem für medikamente |
| US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
| US6606992B1 (en) * | 1999-06-30 | 2003-08-19 | Nektar Therapeutics | Systems and methods for aerosolizing pharmaceutical formulations |
| US7464706B2 (en) * | 1999-07-23 | 2008-12-16 | Mannkind Corporation | Unit dose cartridge and dry powder inhaler |
| US7305986B1 (en) | 1999-07-23 | 2007-12-11 | Mannkind Corporation | Unit dose capsules for use in a dry powder inhaler |
| GB9920839D0 (en) | 1999-09-04 | 1999-11-10 | Innovata Biomed Ltd | Inhaler |
| GB9928265D0 (en) * | 1999-12-01 | 2000-01-26 | Innovata Biomed Ltd | Inhaler |
| US6810872B1 (en) * | 1999-12-10 | 2004-11-02 | Unisia Jecs Corporation | Inhalant medicator |
| WO2001072605A1 (en) * | 2000-03-27 | 2001-10-04 | Dura Pharmaceuticals, Inc. | Containers for individual doses of an inhalable pharmaceutical |
| US7080644B2 (en) * | 2000-06-28 | 2006-07-25 | Microdose Technologies, Inc. | Packaging and delivery of pharmaceuticals and drugs |
| SE517227C2 (sv) * | 2000-09-25 | 2002-05-14 | Microdrug Ag | Inhalator för torrt pulver med folieskärare |
| US6644309B2 (en) | 2001-01-12 | 2003-11-11 | Becton, Dickinson And Company | Medicament respiratory delivery device and method |
| US6722364B2 (en) * | 2001-01-12 | 2004-04-20 | Becton, Dickinson And Company | Medicament inhalation delivery devices and methods for using the same |
| US6443152B1 (en) | 2001-01-12 | 2002-09-03 | Becton Dickinson And Company | Medicament respiratory delivery device |
| MXPA03007017A (es) * | 2001-02-06 | 2004-09-13 | Innovata Biomed Ltd | Medicamentos. |
| FI20011317A0 (fi) * | 2001-06-20 | 2001-06-20 | Orion Corp | Jauheinhalaattori |
| US6681768B2 (en) | 2001-06-22 | 2004-01-27 | Sofotec Gmbh & Co. Kg | Powder formulation disintegrating system and method for dry powder inhalers |
| GB0120018D0 (en) * | 2001-08-16 | 2001-10-10 | Meridica Ltd | Pack containing medicament and dispensing device |
| US6871647B2 (en) * | 2001-09-19 | 2005-03-29 | Advent Pharmaceuticals Pty Ltd | Inhaler |
| GB2380410B (en) * | 2001-10-05 | 2003-11-19 | Alchemy Healthcare Ltd | Apparatus for the nasal or oral delivery of a medicament |
| US7931022B2 (en) | 2001-10-19 | 2011-04-26 | Respirks, Inc. | Method and apparatus for dispensing inhalator medicament |
| GB0128148D0 (en) * | 2001-11-23 | 2002-01-16 | Innovata Biomed Ltd | Assembly |
| US20030168057A1 (en) * | 2001-12-14 | 2003-09-11 | Inhale Therapeutic Systems, Inc. | Electronically controllable aerosol delivery |
| GB0130055D0 (en) * | 2001-12-14 | 2002-02-06 | Technology Innovation Ltd | Medicament packaging |
| DE10202940A1 (de) | 2002-01-24 | 2003-07-31 | Sofotec Gmbh & Co Kg | Patrone für einen Pulverinhalator |
| US7258118B2 (en) | 2002-01-24 | 2007-08-21 | Sofotec Gmbh & Co, Kg | Pharmaceutical powder cartridge, and inhaler equipped with same |
| US6591832B1 (en) * | 2002-02-21 | 2003-07-15 | Saint-Gobain Calmar Inc. | Dry powder dispenser |
| WO2003080149A2 (en) | 2002-03-20 | 2003-10-02 | Mannkind Corporation | Inhalation apparatus |
| GR1004350B (el) | 2002-03-29 | 2003-09-26 | Συσκευη εισπνοων ξηρης σκονης | |
| JP4913325B2 (ja) | 2002-04-19 | 2012-04-11 | スリーエム イノベイティブ プロパティズ カンパニー | 薬用エーロゾルの非呼吸可能分画を慣性除去するためのスペーサ |
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| US6941947B2 (en) * | 2002-12-18 | 2005-09-13 | Quadrant Technologies Limited | Unit dose dry powder inhaler |
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| GB2398253B (en) * | 2003-02-11 | 2005-08-31 | Bespak Plc | Dispensing apparatus |
| GB2398503A (en) | 2003-02-11 | 2004-08-25 | Bespak Plc | Inhaler with removable mouthpiece |
| US7562769B2 (en) * | 2003-03-15 | 2009-07-21 | Brintech International Limited | Formulation and presentation of medicaments |
| US8869794B1 (en) | 2003-04-09 | 2014-10-28 | Novartis Pharma Ag | Aerosolization apparatus with capsule puncturing member |
| KR101066737B1 (ko) * | 2003-04-09 | 2011-09-21 | 노바르티스 아게 | 캡슐 천공 정렬 가이드를 갖는 에어로졸화 장치 |
| ES2383367T5 (es) * | 2003-04-09 | 2021-03-31 | Novartis Ag | Aparato de pulverización en forma de aerosol con protección de entrada de aire |
| EP1488819A1 (en) | 2003-06-16 | 2004-12-22 | Rijksuniversiteit te Groningen | Dry powder inhaler and method for pulmonary inhalation of dry powder |
| GB0320171D0 (en) | 2003-08-28 | 2003-10-01 | Optinose As | Delivery devices |
| WO2005102429A1 (en) * | 2004-04-21 | 2005-11-03 | Innovata Biomed Limited | Inhaler |
| US20070051362A1 (en) * | 2004-04-23 | 2007-03-08 | Sullivan Timothy R | Multiple unit dose drug delivery system |
| GB0409197D0 (en) | 2004-04-24 | 2004-05-26 | Innovata Biomed Ltd | Device |
| US20050263153A1 (en) * | 2004-05-28 | 2005-12-01 | Quadrant Technologies Limited | Unit dose dry powder inhaler |
| USD529604S1 (en) | 2004-05-28 | 2006-10-03 | Quadrant Technologies Limited | Dry powder inhaler |
| BE1015883A3 (fr) * | 2004-06-08 | 2005-10-04 | Occhio | Procede et dispositif de dispersion de poudres seches. |
| JP4621736B2 (ja) | 2004-07-16 | 2011-01-26 | アルミラル ソシエダツド アノニマ | 粉末薬剤を投与するための吸入器、及びこの吸入器と共に使用するための粉末カートリッジシステム |
| MX2007001903A (es) | 2004-08-20 | 2007-08-02 | Mannkind Corp | Catalisis de sintesis de dicetopiperazina. |
| PL2322180T3 (pl) | 2004-08-23 | 2015-10-30 | Mannkind Corp | Sole diketopiperazyny do dostarczania leków |
| US8771257B2 (en) * | 2004-10-15 | 2014-07-08 | Boston Scientific Scimed, Inc. | Drug delivery sheath |
| UA95063C2 (ru) * | 2004-10-21 | 2011-07-11 | Бёрингер Ингельхайм Интернациональ Гмбх | Блистерная упаковка для применения в ингаляторах |
| US8758816B2 (en) * | 2004-11-24 | 2014-06-24 | Meda Pharmaceuticals Inc. | Compositions comprising azelastine and methods of use thereof |
| PT2522365T (pt) * | 2004-11-24 | 2017-02-08 | Meda Pharmaceuticals Inc | Composições que compreendem azelastina e seus métodos de utilização |
| US20070020330A1 (en) | 2004-11-24 | 2007-01-25 | Medpointe Healthcare Inc. | Compositions comprising azelastine and methods of use thereof |
| GB0427853D0 (en) * | 2004-12-20 | 2005-01-19 | Glaxo Group Ltd | Manifold for use in medicament dispenser |
| GB0427856D0 (en) * | 2004-12-20 | 2005-01-19 | Glaxo Group Ltd | Maniflod for use in medicament dispenser |
| GB0427858D0 (en) * | 2004-12-20 | 2005-01-19 | Glaxo Group Ltd | Manifold for use in medicament dispenser |
| GB0507711D0 (en) | 2005-04-15 | 2005-05-25 | Vectura Group Plc | Improved blister piercing |
| CN101171182A (zh) * | 2005-05-02 | 2008-04-30 | 阿斯利康(瑞典)有限公司 | 用于开启凹部的装置和方法、医用密封包及分配设备 |
| US20070012316A1 (en) * | 2005-07-14 | 2007-01-18 | Joann Truza | Disposable compact rescue inhaler |
| BRPI0615819B8 (pt) | 2005-09-14 | 2021-05-25 | Mannkind Corp | processo para preparar uma composição de distribuição de fármaco compreendendo um agente ativo e uma micropartícula fumaril dicetopiperazina cristalina. |
| GB0520794D0 (en) * | 2005-10-12 | 2005-11-23 | Innovata Biomed Ltd | Inhaler |
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1996
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- 1996-06-01 SK SK1758-97A patent/SK282508B6/sk not_active IP Right Cessation
- 1996-06-01 CZ CZ19974136A patent/CZ286678B6/cs not_active IP Right Cessation
- 1996-06-01 DE DE69615033T patent/DE69615033T2/de not_active Expired - Lifetime
- 1996-06-01 RU RU98101919/14A patent/RU2158609C2/ru not_active IP Right Cessation
- 1996-06-01 BR BR9609645A patent/BR9609645A/pt not_active IP Right Cessation
- 1996-06-01 DK DK96917488T patent/DK0835148T3/da active
- 1996-06-01 KR KR1019970709821A patent/KR100253855B1/ko not_active Expired - Fee Related
- 1996-06-01 TR TR97/01732T patent/TR199701732T1/xx unknown
- 1996-06-01 UA UA98010496A patent/UA34505C2/uk unknown
- 1996-06-01 NZ NZ309793A patent/NZ309793A/xx not_active IP Right Cessation
- 1996-06-01 AT AT96917488T patent/ATE205099T1/de not_active IP Right Cessation
- 1996-06-01 JP JP50474397A patent/JP3258025B2/ja not_active Expired - Fee Related
- 1996-06-01 PT PT96917488T patent/PT835148E/pt unknown
- 1996-06-01 CN CN96195196A patent/CN1112222C/zh not_active Expired - Fee Related
- 1996-06-01 CA CA002225999A patent/CA2225999C/en not_active Expired - Fee Related
- 1996-06-01 ES ES96917488T patent/ES2163635T3/es not_active Expired - Lifetime
- 1996-06-01 IL IL12260596A patent/IL122605A/en not_active IP Right Cessation
- 1996-06-01 AU AU60043/96A patent/AU694667B2/en not_active Ceased
- 1996-06-01 HU HU9900116A patent/HU219905B/hu not_active IP Right Cessation
- 1996-06-01 WO PCT/EP1996/002384 patent/WO1997002061A1/en not_active Ceased
- 1996-06-01 EP EP96917488A patent/EP0835148B1/en not_active Expired - Lifetime
- 1996-06-01 PL PL96324333A patent/PL181208B1/pl not_active IP Right Cessation
- 1996-06-25 IN IN1173CA1996 patent/IN188127B/en unknown
- 1996-06-25 AR AR10331496A patent/AR002598A1/es unknown
- 1996-06-27 ZA ZA965484A patent/ZA965484B/xx unknown
- 1996-06-28 US US08/671,739 patent/US5881719A/en not_active Expired - Fee Related
- 1996-06-28 HR HR960300A patent/HRP960300B1/xx not_active IP Right Cessation
- 1996-06-28 TW TW085107858A patent/TW311092B/zh not_active IP Right Cessation
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