CA2116563C - Composition pharmaceutique de gelee seche - Google Patents

Composition pharmaceutique de gelee seche Download PDF

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Publication number
CA2116563C
CA2116563C CA002116563A CA2116563A CA2116563C CA 2116563 C CA2116563 C CA 2116563C CA 002116563 A CA002116563 A CA 002116563A CA 2116563 A CA2116563 A CA 2116563A CA 2116563 C CA2116563 C CA 2116563C
Authority
CA
Canada
Prior art keywords
composition
weight
gel composition
aqueous gel
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002116563A
Other languages
English (en)
Other versions
CA2116563A1 (fr
Inventor
Yoji Ito
Yasuo Hirai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Showa Yakuhin Kako Co Ltd
Original Assignee
Showa Yakuhin Kako Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Showa Yakuhin Kako Co Ltd filed Critical Showa Yakuhin Kako Co Ltd
Publication of CA2116563A1 publication Critical patent/CA2116563A1/fr
Application granted granted Critical
Publication of CA2116563C publication Critical patent/CA2116563C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002116563A 1991-08-30 1992-08-28 Composition pharmaceutique de gelee seche Expired - Fee Related CA2116563C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP22043591 1991-08-30
JP220435/1991 1991-08-30
PCT/JP1992/001097 WO1993004670A1 (fr) 1991-08-30 1992-08-28 Composition de gel sec

Publications (2)

Publication Number Publication Date
CA2116563A1 CA2116563A1 (fr) 1993-03-18
CA2116563C true CA2116563C (fr) 2001-07-03

Family

ID=16751070

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002116563A Expired - Fee Related CA2116563C (fr) 1991-08-30 1992-08-28 Composition pharmaceutique de gelee seche

Country Status (7)

Country Link
US (2) US5496563A (fr)
EP (1) EP0662320B1 (fr)
JP (1) JP3126384B2 (fr)
CA (1) CA2116563C (fr)
DE (1) DE69231856T2 (fr)
DK (1) DK0662320T3 (fr)
WO (1) WO1993004670A1 (fr)

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ATE228773T1 (de) * 1994-10-20 2002-12-15 Chevita Tierarzneimittel Ges M Verfahren zur herstellung von futtermitteln, die pharmakologisch wirksame substanzen enthalten
US5807577A (en) * 1995-11-22 1998-09-15 Lab Pharmaceutical Research International Inc. Fast-melt tablet and method of making same
US5807578A (en) * 1995-11-22 1998-09-15 Lab Pharmaceutical Research International Inc. Fast-melt tablet and method of making same
AU3691297A (en) * 1996-08-15 1998-03-06 Losan Pharma Gmbh Easy to swallow oral medicament composition
US6368625B1 (en) 1998-08-12 2002-04-09 Cima Labs Inc. Orally disintegrable tablet forming a viscous slurry
AU1917900A (en) 1998-11-19 2000-06-05 Corvascular, Inc. Fluid delivery apparatus and methods
USRE39125E1 (en) 2000-03-13 2006-06-13 Ryukakusan Co. Ltd Swallowing-assistive drink
JP4634589B2 (ja) * 2000-09-26 2011-02-16 杏林製薬株式会社 食品又は医薬品易服用化剤
US6777000B2 (en) * 2001-02-28 2004-08-17 Carrington Laboratories, Inc. In-situ gel formation of pectin
JP2005527508A (ja) * 2002-03-07 2005-09-15 ヴェクトゥラ　リミテッド 経口デリバリー用急速溶融多粒子製剤
US7776314B2 (en) * 2002-06-17 2010-08-17 Grunenthal Gmbh Abuse-proofed dosage system
ES2338009T3 (es) * 2003-07-11 2010-05-03 Astrazeneca Ab Composicion solida que comprende un inhibidor de la bomba de protones.
US20070048228A1 (en) 2003-08-06 2007-03-01 Elisabeth Arkenau-Maric Abuse-proofed dosage form
DE10361596A1 (de) 2003-12-24 2005-09-29 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
DE102004032051A1 (de) 2004-07-01 2006-01-19 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform
DE10336400A1 (de) 2003-08-06 2005-03-24 Grünenthal GmbH Gegen Missbrauch gesicherte Darreichungsform
DE102005005446A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Bruchfeste Darreichungsformen mit retardierter Freisetzung
US8075872B2 (en) 2003-08-06 2011-12-13 Gruenenthal Gmbh Abuse-proofed dosage form
DE102004032049A1 (de) 2004-07-01 2006-01-19 Grünenthal GmbH Gegen Missbrauch gesicherte, orale Darreichungsform
DE102005005449A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
JP5414966B2 (ja) * 2006-08-07 2014-02-12 大蔵製薬株式会社 用時調製が可能なゼリー状医薬品
US8343548B2 (en) * 2006-08-08 2013-01-01 Shin-Etsu Chemical Co., Ltd. Solid dosage form comprising solid dispersion
US8519120B2 (en) 2006-08-08 2013-08-27 Shin-Etsu Chemical Co., Ltd. Methods for producing a low-substituted hydroxypropylcellulose powder
US8343547B2 (en) 2006-08-08 2013-01-01 Shin-Etsu Chemical Co., Ltd. Solid dosage form comprising solid dispersion
DE102007011485A1 (de) 2007-03-07 2008-09-11 Grünenthal GmbH Darreichungsform mit erschwertem Missbrauch
CA2713128C (fr) 2008-01-25 2016-04-05 Gruenenthal Gmbh Forme posologique pharmaceutique
EP2273983B1 (fr) 2008-05-09 2016-07-20 Grünenthal GmbH Procédé de préparation d'une formulation de poudre intermédiaire et d'une forme galénique solide finale en utilisant une étape de congélation par pulvérisation
EP2662076A1 (fr) 2009-07-22 2013-11-13 Grünenthal GmbH Forme galénique inviolable stabilisée à l'oxydation
TW201105316A (en) 2009-07-22 2011-02-16 Gruenenthal Gmbh Hot-melt extruded pharmaceutical dosage form
CN102821757B (zh) 2010-02-03 2016-01-20 格吕伦塔尔有限公司 通过挤出机制备粉末状药物组合物
TWI516286B (zh) 2010-09-02 2016-01-11 歌林達股份有限公司 含陰離子聚合物之抗破碎劑型
CN103269688A (zh) 2010-09-02 2013-08-28 格吕伦塔尔有限公司 包含无机盐的抗破碎剂型
NO2736497T3 (fr) 2011-07-29 2018-01-20
EA201400172A1 (ru) 2011-07-29 2014-06-30 Грюненталь Гмбх Устойчивая к разрушению таблетка, которая обеспечивает немедленное высвобождение лекарственного средства
CA2864949A1 (fr) 2012-02-28 2013-09-06 Grunenthal Gmbh Forme pharmaceutique inviolable comprenant un compose pharmacologiquement actif et un polymere anionique
WO2013156453A1 (fr) 2012-04-18 2013-10-24 Grünenthal GmbH Forme pharmaceutique inviolable et résistante à la libération massive
US10064945B2 (en) 2012-05-11 2018-09-04 Gruenenthal Gmbh Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
MX371432B (es) 2013-05-29 2020-01-30 Gruenenthal Gmbh Forma de dosificacion resistente al uso indebido que contiene una o mas particulas.
WO2014191396A1 (fr) 2013-05-29 2014-12-04 Grünenthal GmbH Forme dosifiée inviolable à profil de libération bimodale
JP6449871B2 (ja) 2013-07-12 2019-01-09 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング エチレン−酢酸ビニルポリマーを含有する改変防止剤形
BR112016010482B1 (pt) 2013-11-26 2022-11-16 Grünenthal GmbH Preparação de uma composição farmacêutica em pó por meio de criomoagem
CN106572980A (zh) 2014-05-12 2017-04-19 格吕伦塔尔有限公司 包含他喷他多的防篡改即释胶囊制剂
CN106456550A (zh) 2014-05-26 2017-02-22 格吕伦塔尔有限公司 避免乙醇剂量倾泻的多颗粒
US20160310429A1 (en) 2015-04-24 2016-10-27 Grünenthal GmbH Tamper-resistant dosage form with immediate release and resistance against solvent extraction
US10842750B2 (en) 2015-09-10 2020-11-24 Grünenthal GmbH Protecting oral overdose with abuse deterrent immediate release formulations
WO2017094654A1 (fr) * 2015-11-30 2017-06-08 サントリー食品インターナショナル株式会社 Boisson contenant de l'hydroxytyrosol
JP6629581B2 (ja) * 2015-11-30 2020-01-15 サントリーホールディングス株式会社 ヒドロキシチロソール含有茶飲料
JP6692189B2 (ja) * 2015-11-30 2020-05-13 サントリーホールディングス株式会社 ヒドロキシチロソール含有透明飲料

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4009268A (en) * 1973-01-26 1977-02-22 Arizona Feeds Composition and method for reducing the incidence of scours in neo-natal ruminants
US4332832A (en) * 1978-12-13 1982-06-01 Mars Limited Animal food and method
DK130287D0 (da) * 1987-03-13 1987-03-13 Benzon As Alfred Oralt praeparat
JPH0717511B2 (ja) * 1987-11-12 1995-03-01 花王株式会社 制酸剤含有液状組成物
JPH0262831A (ja) * 1988-08-26 1990-03-02 Fuji Kapuseru Kk ソフトゲル
NZ234143A (en) * 1989-06-28 1991-10-25 Mcneil Ppc Inc Aqueous pharmaceutical suspension formulation for administering substantially insoluble pharmaceutical agents
IT1246350B (it) * 1990-07-11 1994-11-17 Eurand Int Metodo per ottenere una rapida sospensione in acqua di farmaci insolubili
US5262167A (en) * 1990-12-20 1993-11-16 Basf Corporation Edible, non-baked low moisture cholestyramine composition

Also Published As

Publication number Publication date
EP0662320A1 (fr) 1995-07-12
DK0662320T3 (da) 2001-09-24
US5496563A (en) 1996-03-05
US5556640A (en) 1996-09-17
WO1993004670A1 (fr) 1993-03-18
DE69231856D1 (de) 2001-07-05
EP0662320B1 (fr) 2001-05-30
DE69231856T2 (de) 2002-03-28
EP0662320A4 (fr) 1997-03-05
CA2116563A1 (fr) 1993-03-18
JP3126384B2 (ja) 2001-01-22

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