CA2107165A1 - Formulations for nanoparticulate x-ray blood pool contrast agents using high molecular weight nonionic surfactants - Google Patents

Formulations for nanoparticulate x-ray blood pool contrast agents using high molecular weight nonionic surfactants

Info

Publication number
CA2107165A1
CA2107165A1 CA002107165A CA2107165A CA2107165A1 CA 2107165 A1 CA2107165 A1 CA 2107165A1 CA 002107165 A CA002107165 A CA 002107165A CA 2107165 A CA2107165 A CA 2107165A CA 2107165 A1 CA2107165 A1 CA 2107165A1
Authority
CA
Canada
Prior art keywords
composition
cloud point
modifier
molecular weight
nanoparticle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002107165A
Other languages
English (en)
French (fr)
Inventor
George C. Na
Natarajan Rajagopalan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nanosystems LLC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2107165A1 publication Critical patent/CA2107165A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
    • A61K49/0476—Particles, beads, capsules, spheres
    • A61K49/0485—Nanoparticles, nanobeads, nanospheres, nanocapsules, i.e. having a size or diameter smaller than 1 micrometer
    • A61K49/049—Surface-modified nanoparticles, e.g. immune-nanoparticles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Nanotechnology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA002107165A 1992-12-17 1993-09-28 Formulations for nanoparticulate x-ray blood pool contrast agents using high molecular weight nonionic surfactants Abandoned CA2107165A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US991,909 1992-12-17
US07/991,909 US5326552A (en) 1992-12-17 1992-12-17 Formulations for nanoparticulate x-ray blood pool contrast agents using high molecular weight nonionic surfactants

Publications (1)

Publication Number Publication Date
CA2107165A1 true CA2107165A1 (en) 1994-06-18

Family

ID=25537712

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002107165A Abandoned CA2107165A1 (en) 1992-12-17 1993-09-28 Formulations for nanoparticulate x-ray blood pool contrast agents using high molecular weight nonionic surfactants

Country Status (17)

Country Link
US (2) US5326552A (enExample)
EP (1) EP0602700A3 (enExample)
JP (1) JPH06192131A (enExample)
KR (1) KR940013544A (enExample)
AU (1) AU664115B2 (enExample)
CA (1) CA2107165A1 (enExample)
CZ (1) CZ266893A3 (enExample)
FI (1) FI935396L (enExample)
HU (1) HUT67265A (enExample)
IL (1) IL107875A0 (enExample)
MX (1) MX9306012A (enExample)
MY (1) MY109875A (enExample)
NO (1) NO934425L (enExample)
NZ (1) NZ248727A (enExample)
PH (1) PH30158A (enExample)
SK (1) SK142793A3 (enExample)
TW (1) TW240171B (enExample)

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EP0602700A2 (en) 1994-06-22
NZ248727A (en) 1995-04-27
EP0602700A3 (en) 1994-12-21
AU4867293A (en) 1994-06-30
FI935396A0 (fi) 1993-12-02
KR940013544A (ko) 1994-07-15
TW240171B (enExample) 1995-02-11
NO934425D0 (no) 1993-12-06
PH30158A (en) 1997-01-21
HUT67265A (en) 1995-03-28
SK142793A3 (en) 1994-07-06
US5447710A (en) 1995-09-05
AU664115B2 (en) 1995-11-02
NO934425L (no) 1994-06-20
FI935396A7 (fi) 1994-06-18
IL107875A0 (en) 1994-04-12
MY109875A (en) 1997-09-30
US5326552A (en) 1994-07-05
FI935396L (fi) 1994-06-18
HU9303490D0 (en) 1994-04-28
MX9306012A (es) 1995-01-31
JPH06192131A (ja) 1994-07-12
CZ266893A3 (en) 1994-08-17

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