CA2105251C - Novel processes for the production of 13-ether derivatives of milbemycins, and novel intermediates therefor - Google Patents

Novel processes for the production of 13-ether derivatives of milbemycins, and novel intermediates therefor Download PDF

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Publication number
CA2105251C
CA2105251C CA002105251A CA2105251A CA2105251C CA 2105251 C CA2105251 C CA 2105251C CA 002105251 A CA002105251 A CA 002105251A CA 2105251 A CA2105251 A CA 2105251A CA 2105251 C CA2105251 C CA 2105251C
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CA
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group
groups
formula
compound
defined above
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Expired - Fee Related
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CA002105251A
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English (en)
French (fr)
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CA2105251A1 (en
Inventor
Mitsugi Shibano
Mutsuo Suzuki
Shunshi Kojima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsui Chemicals Agro Inc
Elanco Japan KK
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Sankyo Agro Co Ltd
Sankyo Lifetech Co Ltd
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Publication of CA2105251A1 publication Critical patent/CA2105251A1/en
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Publication of CA2105251C publication Critical patent/CA2105251C/en
Anticipated expiration legal-status Critical
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
CA002105251A 1992-09-01 1993-08-31 Novel processes for the production of 13-ether derivatives of milbemycins, and novel intermediates therefor Expired - Fee Related CA2105251C (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP23344492 1992-09-01
JP26366092 1992-10-01
JP4-322847 1992-12-02
JP4-233444 1992-12-02
JP32284792 1992-12-02
JP4-263660 1992-12-02

Publications (2)

Publication Number Publication Date
CA2105251A1 CA2105251A1 (en) 1994-03-02
CA2105251C true CA2105251C (en) 2004-12-07

Family

ID=27331997

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002105251A Expired - Fee Related CA2105251C (en) 1992-09-01 1993-08-31 Novel processes for the production of 13-ether derivatives of milbemycins, and novel intermediates therefor

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US (2) US5461168A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0594291B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JP2654337B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR0161541B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE229960T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU666750B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2105251C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE69332577T2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK0594291T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2186672T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ248559A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT594291E (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TW (1) TW262474B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

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KR100612634B1 (ko) * 1998-05-25 2006-08-14 상꾜 아그로 가부시키가이샤 밀베마이신류의 13-에스테르 유도체의 제조법
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US5461168A (en) 1995-10-24
DE69332577T2 (de) 2003-11-20
CA2105251A1 (en) 1994-03-02
PT594291E (pt) 2003-03-31
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US5625078A (en) 1997-04-29
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ATE229960T1 (de) 2003-01-15
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