CA2087270C - Baculovirus modifie, son procede d'obtention, et vecteurs d'expression obtenus a partir dudit baculovirus - Google Patents

Baculovirus modifie, son procede d'obtention, et vecteurs d'expression obtenus a partir dudit baculovirus Download PDF

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Publication number
CA2087270C
CA2087270C CA002087270A CA2087270A CA2087270C CA 2087270 C CA2087270 C CA 2087270C CA 002087270 A CA002087270 A CA 002087270A CA 2087270 A CA2087270 A CA 2087270A CA 2087270 C CA2087270 C CA 2087270C
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CA
Canada
Prior art keywords
baculovirus
sequence
promoter
modified
gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002087270A
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English (en)
French (fr)
Other versions
CA2087270A1 (fr
Inventor
Gerard Devauchelle
Martine Cerutti
Claire Cahoreau
Marianne Martin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Institut National de la Recherche Agronomique INRA
Original Assignee
Centre National de la Recherche Scientifique CNRS
Institut National de la Recherche Agronomique INRA
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Publication of CA2087270A1 publication Critical patent/CA2087270A1/fr
Application granted granted Critical
Publication of CA2087270C publication Critical patent/CA2087270C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/14011Baculoviridae
    • C12N2710/14111Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
    • C12N2710/14141Use of virus, viral particle or viral elements as a vector
    • C12N2710/14143Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA002087270A 1990-07-18 1991-07-17 Baculovirus modifie, son procede d'obtention, et vecteurs d'expression obtenus a partir dudit baculovirus Expired - Fee Related CA2087270C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR909009143A FR2664905B1 (fr) 1990-07-18 1990-07-18 Baculovirus modifie, son procede d'obtention, et vecteurs d'expression obtenus a partir dudit baculovirus.
FR90/09143 1990-07-18
PCT/FR1991/000588 WO1992001801A1 (fr) 1990-07-18 1991-07-17 Baculovirus modifie, son procede d'obtention, et vecteurs d'expression obtenus a partir dudit baculovirus

Publications (2)

Publication Number Publication Date
CA2087270A1 CA2087270A1 (fr) 1992-01-19
CA2087270C true CA2087270C (fr) 2001-12-04

Family

ID=9398840

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002087270A Expired - Fee Related CA2087270C (fr) 1990-07-18 1991-07-17 Baculovirus modifie, son procede d'obtention, et vecteurs d'expression obtenus a partir dudit baculovirus

Country Status (14)

Country Link
US (1) US5571709A (no)
EP (1) EP0651815B1 (no)
JP (1) JP3076833B2 (no)
AT (1) ATE151462T1 (no)
AU (1) AU660419B2 (no)
CA (1) CA2087270C (no)
DE (1) DE69125632T2 (no)
FR (1) FR2664905B1 (no)
HU (1) HUT62937A (no)
IE (1) IE912525A1 (no)
NO (1) NO930145L (no)
NZ (1) NZ239032A (no)
PT (1) PT98357B (no)
WO (1) WO1992001801A1 (no)

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JP2003040297A (ja) * 2001-08-06 2003-02-13 Toppan Printing Co Ltd オーバーキャップ付封緘キャップ
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EP1615945B1 (en) 2003-04-09 2011-09-28 BioGeneriX AG Glycopegylation methods and proteins/peptides produced by the methods
JP4889505B2 (ja) 2004-02-02 2012-03-07 アンブレツクス・インコーポレイテツド 被修飾されたヒト成長ホルモンポリペプチドおよびこれらの使用
JP2008503217A (ja) 2004-06-18 2008-02-07 アンブレツクス・インコーポレイテツド 新規抗原結合ポリペプチド及びそれらの使用
CA2569381A1 (en) 2004-07-21 2006-08-31 Ambrx, Inc. Biosynthetic polypeptides utilizing non-naturally encoded amino acids
WO2009100255A2 (en) 2008-02-08 2009-08-13 Ambrx, Inc. Modified leptin polypeptides and their uses
KR20070090023A (ko) 2004-12-22 2007-09-04 암브룩스, 인코포레이티드 변형 인간 성장 호르몬
JP2008525032A (ja) 2004-12-22 2008-07-17 アンブレツクス・インコーポレイテツド 組換えヒト成長ホルモンを発現及び精製するための方法
WO2006068802A2 (en) 2004-12-22 2006-06-29 Ambrx, Inc. COMPOSITIONS OF AMINOACYL-tRNA SYNTHETASE AND USES THEREOF
KR101224781B1 (ko) 2004-12-22 2013-01-21 암브룩스, 인코포레이티드 비천연적으로 코딩된 아미노산을 포함하는 인간 성장호르몬의 조제물
WO2006069246A2 (en) 2004-12-22 2006-06-29 Ambrx, Inc. Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides
CA2609205A1 (en) * 2005-06-03 2006-12-14 Ambrx, Inc. Improved human interferon molecules and their uses
AU2005335491B2 (en) * 2005-08-18 2010-11-25 Ambrx, Inc. Compositions of tRNA and uses thereof
ATE500215T1 (de) * 2005-11-08 2011-03-15 Ambrx Inc Beschleuniger für die modifikation nichtnatürlicher aminosäuren und nichtnatürlicher aminosäurepolypeptide
ES2547554T3 (es) * 2005-11-16 2015-10-07 Ambrx, Inc. Métodos y composiciones que comprenden aminoácidos no naturales
KR101423898B1 (ko) * 2005-12-14 2014-07-28 암브룩스, 인코포레이티드 비-천연 아미노산 및 폴리펩티드를 함유하는 조성물, 비-천연 아미노산 및 폴리펩티드를 포함하는 방법, 및 비-천연 아미노산 및 폴리펩티드의 용도
CN101541955B (zh) 2006-09-08 2016-09-28 Ambrx公司 用于脊椎动物细胞的杂合抑制tRNA
EP2069396B1 (en) 2006-09-08 2015-10-21 Ambrx, Inc. Modified human plasma polypeptide or fc scaffolds and their uses
PT2064333E (pt) 2006-09-08 2014-06-09 Ambrx Inc Supressor híbrido arnt para células de vertebrados
PL2068909T3 (pl) 2007-03-30 2012-09-28 Ambrx Inc Modyfikowane polipeptydy fgf-21 i ich zastosowanie
EP2076533B1 (en) 2007-05-02 2014-10-08 Ambrx, Inc. Modified interferon beta polypeptides and their uses
ES2632504T3 (es) 2007-11-20 2017-09-13 Ambrx, Inc. Polipéptidos de insulina modificados y sus usos
JP5680534B2 (ja) 2008-07-23 2015-03-04 イーライ リリー アンド カンパニー 修飾されているウシg−csfポリペプチドおよびそれらの使用
PE20110832A1 (es) 2008-09-26 2011-11-24 Ambrx Inc Polipeptidos de eritropoyetina felina modificados
MX348657B (es) 2008-09-26 2017-06-21 Ambrx Inc Microorganismos y vacunas dependientes de replicacion de aminoacidos no naturales.
WO2010117786A1 (en) * 2009-03-30 2010-10-14 Mount Sinai School Of Medicine Of New York University Influenza virus vaccines and uses thereof
AU2010254136B2 (en) 2009-05-26 2016-09-29 Mount Sinai School Of Medicine Monoclonal antibodies against influenza virus generated by cyclical administration and uses thereof
WO2010144794A1 (en) 2009-06-12 2010-12-16 Vaccine Technologies, Incorporated Baculovirus-expressed fusion polypeptide vaccines with enhanced immunogenicity and uses thereof
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EA201290541A1 (ru) 2009-12-21 2013-05-30 Амбркс, Инк. Модифицированные бычьи соматотропиновые полипептиды и их применение
CN102666578A (zh) 2009-12-21 2012-09-12 Ambrx公司 经过修饰的猪促生长素多肽和其用途
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US9567386B2 (en) 2010-08-17 2017-02-14 Ambrx, Inc. Therapeutic uses of modified relaxin polypeptides
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RU2632651C2 (ru) 2011-05-11 2017-10-06 Чилдрен'С Медикал Сентер Корпорейшн Модифицированный биотин-связывающий белок, слитые белки на его основе и их применение
IN2014CN00688A (no) * 2011-07-27 2015-04-03 Genethon
US10131695B2 (en) 2011-09-20 2018-11-20 Icahn School Of Medicine At Mount Sinai Influenza virus vaccines and uses thereof
JP2016508133A (ja) 2012-12-18 2016-03-17 アイカーン スクール オブ メディシン アット マウント サイナイ インフルエンザウイルスワクチン及びその使用
EP3511417B1 (en) 2013-01-28 2023-05-31 Kansas State University Research Foundation Rift valley fever virus glycoproteins, gn and gc, and their use
WO2014159960A1 (en) 2013-03-14 2014-10-02 Icahn School Of Medicine At Mount Sinai Antibodies against influenza virus hemagglutinin and uses thereof
JP6702962B2 (ja) 2014-10-24 2020-06-03 ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company 改変fgf−21ポリペプチドおよびその使用
JP2018504412A (ja) 2015-01-23 2018-02-15 アイカーン スクール オブ メディシン アット マウント サイナイ インフルエンザウイルスワクチン接種レジメン
CA3023143A1 (en) 2016-06-15 2017-12-21 Icahn School Of Medicine At Mount Sinai Influenza virus hemagglutinin proteins and uses thereof
CN110637027A (zh) 2017-02-08 2019-12-31 百时美施贵宝公司 包含药代动力学增强子的修饰的松弛素多肽及其用途
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ATE78293T1 (de) * 1983-05-27 1992-08-15 Texas A & M Univ Sys Verfahren zur herstellung eines rekombinanten baculovirus-expressionsvektors.

Also Published As

Publication number Publication date
AU8232491A (en) 1992-02-18
NO930145D0 (no) 1993-01-15
EP0651815A1 (fr) 1995-05-10
PT98357B (pt) 1999-01-29
PT98357A (pt) 1992-05-29
HU9300118D0 (en) 1993-04-28
DE69125632T2 (de) 1997-10-23
WO1992001801A1 (fr) 1992-02-06
FR2664905B1 (fr) 1994-08-12
JPH06500010A (ja) 1994-01-06
CA2087270A1 (fr) 1992-01-19
JP3076833B2 (ja) 2000-08-14
NZ239032A (en) 1993-10-26
ATE151462T1 (de) 1997-04-15
HUT62937A (en) 1993-06-28
EP0651815B1 (fr) 1997-04-09
DE69125632D1 (de) 1997-05-15
FR2664905A1 (fr) 1992-01-24
IE912525A1 (en) 1992-01-29
US5571709A (en) 1996-11-05
NO930145L (no) 1993-03-15
AU660419B2 (en) 1995-06-29

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