CA2006184C - Prolonged release composition based on trimebutine and process for the preparation thereof - Google Patents

Prolonged release composition based on trimebutine and process for the preparation thereof

Info

Publication number
CA2006184C
CA2006184C CA002006184A CA2006184A CA2006184C CA 2006184 C CA2006184 C CA 2006184C CA 002006184 A CA002006184 A CA 002006184A CA 2006184 A CA2006184 A CA 2006184A CA 2006184 C CA2006184 C CA 2006184C
Authority
CA
Canada
Prior art keywords
active agent
tablet
composition
hydroxypropylmethylcellulose
tartaric acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002006184A
Other languages
English (en)
French (fr)
Other versions
CA2006184A1 (en
Inventor
Loufty Omar Benkerrour
Francoise Chanoine
Jacques Sylvain Frances
Jean-Louis Junien
Gilbert Aubard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jouveinal SA
Original Assignee
Jouveinal SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jouveinal SA filed Critical Jouveinal SA
Publication of CA2006184A1 publication Critical patent/CA2006184A1/en
Application granted granted Critical
Publication of CA2006184C publication Critical patent/CA2006184C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Fats And Perfumes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002006184A 1988-12-28 1989-12-20 Prolonged release composition based on trimebutine and process for the preparation thereof Expired - Lifetime CA2006184C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8817303 1988-12-28
FR8817303A FR2640876B1 (xx) 1988-12-28 1988-12-28

Publications (2)

Publication Number Publication Date
CA2006184A1 CA2006184A1 (en) 1990-06-28
CA2006184C true CA2006184C (en) 1999-11-23

Family

ID=9373520

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002006184A Expired - Lifetime CA2006184C (en) 1988-12-28 1989-12-20 Prolonged release composition based on trimebutine and process for the preparation thereof

Country Status (14)

Country Link
JP (1) JP2745232B2 (xx)
KR (1) KR0137270B1 (xx)
AT (1) AT397461B (xx)
BE (1) BE1006002A4 (xx)
CA (1) CA2006184C (xx)
DE (1) DE3942131C2 (xx)
EG (1) EG19994A (xx)
ES (1) ES2019024A6 (xx)
FR (1) FR2640876B1 (xx)
GR (1) GR1000429B (xx)
GT (1) GT198900080A (xx)
IT (1) IT1236239B (xx)
MX (1) MX170641B (xx)
PT (1) PT92682B (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05255125A (ja) * 1992-02-29 1993-10-05 Upjohn Co:The 徐放性製剤およびその製法
FR2730163B1 (fr) * 1995-02-03 1997-04-04 Jouveinal Lab Nouvelle composition pharmaceutique contenant la trimebutine et son procede de preparation
FR2752162B1 (fr) * 1996-08-07 1998-11-06 Jouveinal Lab Comprime de maleate de trimebutine pellicule
CN1927185B (zh) * 2006-10-19 2010-05-19 开开援生制药股份有限公司 具速释部分的马来酸曲美布汀缓释片及其制备工艺
KR101051630B1 (ko) * 2008-10-02 2011-07-26 한국유나이티드제약 주식회사 용출률과 복용편의성이 향상된 트리메부틴 서방정
FR2944971B1 (fr) * 2009-04-30 2012-09-07 Roquette Freres Coagglomerats de mannitol et d'amidon granulaire comprimables et a ecoulement libre

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3065143A (en) * 1960-04-19 1962-11-20 Richardson Merrell Inc Sustained release tablet
JPS57197214A (en) * 1981-05-29 1982-12-03 Tanabe Seiyaku Co Ltd Rapid-releasing microcapsule and its preparation
JPS5858146A (ja) * 1981-10-05 1983-04-06 Tanabe Seiyaku Co Ltd 速放性マイクロカプセル
JPS5858145A (ja) * 1981-10-05 1983-04-06 Tanabe Seiyaku Co Ltd 速放性マイクロカプセル
JPS5916821A (ja) * 1982-07-16 1984-01-28 Tanabe Seiyaku Co Ltd 非凝集性マイクロカプセルの製法
IT1206166B (it) * 1984-07-26 1989-04-14 Sigma Tau Ind Farmaceuti Dispositivo per rilasciare una sostanza in un fluido di dissoluzione con cinetica di ordine zero e procedimento per la sua preparazione
GB8616669D0 (en) * 1986-07-09 1986-08-13 Merk Sharpe & Dohme Ltd Pharmaceutical compositions

Also Published As

Publication number Publication date
DE3942131A1 (de) 1990-07-05
JPH02184624A (ja) 1990-07-19
KR0137270B1 (ko) 1998-04-25
EG19994A (en) 1997-01-30
GR1000429B (el) 1992-07-30
IT8912615A0 (it) 1989-12-20
PT92682B (pt) 1997-01-31
CA2006184A1 (en) 1990-06-28
GR890100860A (en) 1991-03-15
KR900009060A (ko) 1990-07-02
JP2745232B2 (ja) 1998-04-28
PT92682A (pt) 1990-06-29
AT397461B (de) 1994-04-25
FR2640876B1 (xx) 1993-09-24
BE1006002A4 (fr) 1994-04-19
IT1236239B (it) 1993-01-27
MX170641B (es) 1993-09-01
DE3942131C2 (de) 1998-09-17
IT8912615A1 (it) 1991-06-20
ATA294489A (de) 1993-09-15
GT198900080A (es) 1991-06-20
FR2640876A1 (xx) 1990-06-29
ES2019024A6 (es) 1991-05-16

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