CA1217496A - L-phenoxy-3-hydroxyindolylalkylamino-3-propanols and preparation - Google Patents

L-phenoxy-3-hydroxyindolylalkylamino-3-propanols and preparation

Info

Publication number
CA1217496A
CA1217496A CA000456154A CA456154A CA1217496A CA 1217496 A CA1217496 A CA 1217496A CA 000456154 A CA000456154 A CA 000456154A CA 456154 A CA456154 A CA 456154A CA 1217496 A CA1217496 A CA 1217496A
Authority
CA
Canada
Prior art keywords
hydrogen
compound
hydroxy
whenever prepared
indole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000456154A
Other languages
English (en)
French (fr)
Inventor
William E. Kreighbaum
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Application granted granted Critical
Publication of CA1217496A publication Critical patent/CA1217496A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA000456154A 1983-06-10 1984-06-08 L-phenoxy-3-hydroxyindolylalkylamino-3-propanols and preparation Expired CA1217496A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50290183A 1983-06-10 1983-06-10
US502,901 1990-04-02

Publications (1)

Publication Number Publication Date
CA1217496A true CA1217496A (en) 1987-02-03

Family

ID=23999880

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000456154A Expired CA1217496A (en) 1983-06-10 1984-06-08 L-phenoxy-3-hydroxyindolylalkylamino-3-propanols and preparation

Country Status (29)

Country Link
JP (1) JPS608262A (el)
KR (1) KR900005021B1 (el)
AT (1) AT381492B (el)
AU (1) AU569303B2 (el)
BE (1) BE899875A (el)
CA (1) CA1217496A (el)
CH (1) CH662561A5 (el)
CY (1) CY1518A (el)
DE (1) DE3421252A1 (el)
DK (1) DK162089C (el)
ES (1) ES8507490A1 (el)
FI (1) FI78291C (el)
FR (1) FR2549054B1 (el)
GB (1) GB2141121B (el)
GR (1) GR82208B (el)
HK (1) HK14690A (el)
HU (1) HU191670B (el)
IE (1) IE57682B1 (el)
IL (1) IL72008A (el)
IT (1) IT1206705B (el)
LU (1) LU85410A1 (el)
MY (1) MY102077A (el)
NL (1) NL8401840A (el)
NO (1) NO164471C (el)
NZ (1) NZ208337A (el)
SE (1) SE455865B (el)
SG (1) SG1090G (el)
YU (1) YU44873B (el)
ZA (1) ZA844277B (el)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601008B1 (fr) * 1986-07-03 1990-03-30 Sanofi Sa Procede de synthese stereospecifique de derives de l'indole
KR101986648B1 (ko) 2018-04-06 2019-06-07 (유)로뎀건설 강관작업구 굴착장치

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB962793A (en) * 1959-07-13 1964-07-01 Philips Nv Improvements in or relating to pharmacologically active compounds being substituted tryptamines
NL300886A (el) * 1962-11-23
US4314943A (en) * 1977-07-13 1982-02-09 Mead Johnson & Company Heterocyclic substituted aryloxy 3-indolyl-tertiary butylaminopropanols
CA1116598A (en) * 1977-07-13 1982-01-19 William T. Comer 3-indolyl-tertiary butylaminopropanols
US4234595A (en) * 1977-07-13 1980-11-18 Mead Johnson & Company 3-Indolyl-tertiary butylaminopropanols
FR2463765A1 (fr) * 1979-08-17 1981-02-27 Clin Midy Nouveaux derives de l'indole actifs sur le systeme cardiovasculaire

Also Published As

Publication number Publication date
YU44873B (en) 1991-04-30
SG1090G (en) 1990-07-06
SE455865B (sv) 1988-08-15
YU99784A (en) 1986-10-31
GB2141121A (en) 1984-12-12
FR2549054A1 (fr) 1985-01-18
GB2141121B (en) 1987-01-07
SE8403112D0 (sv) 1984-06-08
KR900005021B1 (ko) 1990-07-18
IE57682B1 (en) 1993-02-24
HUT34445A (en) 1985-03-28
SE8403112L (sv) 1984-12-11
LU85410A1 (fr) 1985-03-26
DK284184A (da) 1984-12-11
HU191670B (en) 1987-03-30
HK14690A (en) 1990-03-02
CH662561A5 (de) 1987-10-15
FI842316A0 (fi) 1984-06-07
FI78291B (fi) 1989-03-31
MY102077A (en) 1992-03-31
DK284184D0 (da) 1984-06-08
ATA186784A (de) 1986-03-15
NO164471B (no) 1990-07-02
JPH0587503B2 (el) 1993-12-16
NO164471C (no) 1990-10-10
NL8401840A (nl) 1985-01-02
IT1206705B (it) 1989-04-27
IE841441L (en) 1984-12-10
DE3421252A1 (de) 1984-12-13
NO842279L (no) 1984-12-11
KR850000396A (ko) 1985-02-27
AT381492B (de) 1986-10-27
FI78291C (fi) 1989-07-10
ZA844277B (en) 1985-03-27
IL72008A (en) 1988-05-31
ES533185A0 (es) 1985-09-16
CY1518A (en) 1990-11-16
DK162089B (da) 1991-09-16
DK162089C (da) 1992-02-24
ES8507490A1 (es) 1985-09-16
GR82208B (el) 1984-12-13
IT8421330A0 (it) 1984-06-08
NZ208337A (en) 1988-10-28
AU2923884A (en) 1984-12-13
JPS608262A (ja) 1985-01-17
AU569303B2 (en) 1988-01-28
IL72008A0 (en) 1984-10-31
FI842316A (fi) 1984-12-11
GB8414652D0 (en) 1984-07-11
FR2549054B1 (fr) 1988-03-04
BE899875A (fr) 1984-12-10

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