CA1211440A - Carboxamido-derivatives of 5h-1,3,4-thiadiazolo ¬3, 2-a| pyrimidines and process for their preparation - Google Patents
Carboxamido-derivatives of 5h-1,3,4-thiadiazolo ¬3, 2-a| pyrimidines and process for their preparationInfo
- Publication number
- CA1211440A CA1211440A CA000444151A CA444151A CA1211440A CA 1211440 A CA1211440 A CA 1211440A CA 000444151 A CA000444151 A CA 000444151A CA 444151 A CA444151 A CA 444151A CA 1211440 A CA1211440 A CA 1211440A
- Authority
- CA
- Canada
- Prior art keywords
- pyridyl
- oxo
- carboxamide
- group
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
- C07D285/125—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
- C07D285/135—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Rheumatology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8236642 | 1982-12-23 | ||
| GB8236642 | 1982-12-23 | ||
| GB838329746A GB8329746D0 (en) | 1983-11-08 | 1983-11-08 | Carboxamido-derivatives |
| GB8329746 | 1983-11-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1211440A true CA1211440A (en) | 1986-09-16 |
Family
ID=26284768
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000444151A Expired CA1211440A (en) | 1982-12-23 | 1983-12-22 | Carboxamido-derivatives of 5h-1,3,4-thiadiazolo ¬3, 2-a| pyrimidines and process for their preparation |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4522944A (enExample) |
| AT (1) | AT385036B (enExample) |
| AU (1) | AU558600B2 (enExample) |
| CA (1) | CA1211440A (enExample) |
| CH (1) | CH657136A5 (enExample) |
| DE (1) | DE3346223A1 (enExample) |
| DK (1) | DK593983A (enExample) |
| FI (1) | FI834698A7 (enExample) |
| FR (1) | FR2538392B1 (enExample) |
| GR (1) | GR79479B (enExample) |
| IL (1) | IL70522A (enExample) |
| IT (1) | IT1194521B (enExample) |
| NL (1) | NL8304340A (enExample) |
| SE (1) | SE454698B (enExample) |
| SU (1) | SU1297731A3 (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3702758A1 (de) * | 1987-01-30 | 1988-09-29 | Hoechst Ag | Substituierte 3-phenyl-7h-thiazolo (3,2-b) (1,2,4) triazin-7-one, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung, sowie einige bei der herstellung der genannten verbindungen gebildete zwischenprodukte |
| JP5567349B2 (ja) | 2007-03-12 | 2014-08-06 | イントラ−セルラー・セラピーズ・インコーポレイテッド | 置換ヘテロ環縮合ガンマ−カルボリンの合成 |
| US11053245B2 (en) | 2012-04-14 | 2021-07-06 | Intra-Cellular Therapies, Inc. | Methods |
| PL2968320T3 (pl) | 2013-03-15 | 2021-05-17 | Intra-Cellular Therapies, Inc. | Związki organiczne |
| KR102373288B1 (ko) | 2013-12-03 | 2022-03-10 | 인트라-셀룰라 써래피스, 인코퍼레이티드. | 신규한 방법 |
| BR112016023162B1 (pt) | 2014-04-04 | 2022-11-29 | Intra-Cellular Therapies, Inc | Compostos orgânicos gama-carbolinas, composições farmacêuticas compreendendo os ditos compostos e uso dos mesmos no tratamento ou na profilaxia de transtornos de sistema nervoso central |
| JP2017509677A (ja) | 2014-04-04 | 2017-04-06 | イントラ−セルラー・セラピーズ・インコーポレイテッドＩｎｔｒａ−Ｃｅｌｌｕｌａｒ Ｔｈｅｒａｐｉｅｓ， Ｉｎｃ． | 有機化合物 |
| IL296884B2 (en) | 2016-01-26 | 2024-05-01 | Intra Cellular Therapies Inc | Condensed heterocyclic converted gamma carbonyls for use in the treatment of central nervous system disorders |
| JP2019510039A (ja) | 2016-03-28 | 2019-04-11 | イントラ−セルラー・セラピーズ・インコーポレイテッドＩｎｔｒａ−Ｃｅｌｌｕｌａｒ Ｔｈｅｒａｐｉｅｓ， Ｉｎｃ． | 新規組成物および方法 |
| JP6997718B2 (ja) | 2016-03-28 | 2022-01-18 | イントラ－セルラー・セラピーズ・インコーポレイテッド | 新規共結晶 |
| WO2017172784A1 (en) | 2016-03-28 | 2017-10-05 | Intra-Cellular Therapies, Inc. | Novel salts and crystals |
| WO2018071233A1 (en) | 2016-10-12 | 2018-04-19 | Intra-Cellular Therapies, Inc. | Amorphous solid dispersions |
| WO2018126140A1 (en) | 2016-12-29 | 2018-07-05 | Intra-Cellular Therapies, Inc. | Organic compounds |
| WO2018126143A1 (en) | 2016-12-29 | 2018-07-05 | Intra-Cellular Therapies, Inc. | Organic compounds |
| CN116327770B (zh) | 2017-03-24 | 2025-10-31 | 细胞内治疗公司 | 新组合物和方法 |
| CA3071119A1 (en) | 2017-07-26 | 2019-01-31 | Intra-Cellular Therapies, Inc. | Substituted heterocycle fused gamma-carbolines for treatment or prophylaxis of central nervous system disorders |
| AU2018307480B2 (en) | 2017-07-26 | 2023-11-23 | Intra-Cellular Therapies, Inc. | Organic compounds |
| CA3094949A1 (en) | 2018-03-23 | 2019-09-26 | Intra-Cellular Therapies, Inc. | Deuterated heterocycle fused gamma-carbolines |
| CA3102848A1 (en) | 2018-06-06 | 2019-12-12 | Intra-Cellular Therapies, Inc. | Novel salts and crystals |
| MX2020013335A (es) | 2018-06-08 | 2021-05-27 | Intra Cellular Therapies Inc | Metodos novedosos. |
| AU2019287460B2 (en) | 2018-06-11 | 2024-02-15 | Intra-Cellular Therapies, Inc. | Substituted heterocycle fused gamma-carbolines synthesis |
| US12144808B2 (en) | 2018-08-29 | 2024-11-19 | Intra-Cellular Therapies, Inc. | Compositions and methods |
| AU2019331490B2 (en) | 2018-08-31 | 2025-04-24 | Intra-Cellular Therapies, Inc. | Novel methods |
| MX2021002322A (es) | 2018-08-31 | 2021-04-28 | Intra Cellular Therapies Inc | Nuevos metodos. |
| CA3141223A1 (en) | 2019-07-07 | 2021-01-14 | Sharon Mates | Novel methods |
| EP4072554A4 (en) | 2019-12-11 | 2023-12-20 | Intra-Cellular Therapies, Inc. | ORGANIC COMPOUND |
| US12414948B2 (en) | 2022-05-18 | 2025-09-16 | Intra-Cellular Therapies, Inc. | Methods |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5129981B2 (enExample) * | 1973-07-17 | 1976-08-28 | ||
| GB1568962A (en) * | 1975-10-31 | 1980-06-11 | Beecham Group Ltd | Reparation and compositions containing them (heterocyclic-carbonylamino)pencillins methods for their p |
| JPS55115889A (en) * | 1979-02-28 | 1980-09-06 | Teijin Ltd | 6-carbamoylthiazolo 3,2-a pyrimidine derivative and its preparation |
| JPS57142989A (en) * | 1981-02-27 | 1982-09-03 | Dai Ichi Seiyaku Co Ltd | Thiazolopyrimidine derivative |
-
1983
- 1983-12-08 US US06/559,322 patent/US4522944A/en not_active Expired - Fee Related
- 1983-12-15 AT AT0438383A patent/AT385036B/de not_active IP Right Cessation
- 1983-12-15 GR GR73259A patent/GR79479B/el unknown
- 1983-12-16 IT IT24207/83A patent/IT1194521B/it active
- 1983-12-16 NL NL8304340A patent/NL8304340A/nl not_active Application Discontinuation
- 1983-12-19 AU AU22525/83A patent/AU558600B2/en not_active Ceased
- 1983-12-20 CH CH6783/83A patent/CH657136A5/de not_active IP Right Cessation
- 1983-12-20 FI FI834698A patent/FI834698A7/fi not_active Application Discontinuation
- 1983-12-21 DE DE19833346223 patent/DE3346223A1/de not_active Withdrawn
- 1983-12-22 DK DK593983A patent/DK593983A/da not_active Application Discontinuation
- 1983-12-22 SU SU833682101A patent/SU1297731A3/ru active
- 1983-12-22 IL IL70522A patent/IL70522A/xx not_active IP Right Cessation
- 1983-12-22 SE SE8307133A patent/SE454698B/sv not_active IP Right Cessation
- 1983-12-22 CA CA000444151A patent/CA1211440A/en not_active Expired
- 1983-12-23 FR FR8320704A patent/FR2538392B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GR79479B (enExample) | 1984-10-30 |
| ATA438383A (de) | 1987-07-15 |
| IL70522A0 (en) | 1984-03-30 |
| FR2538392A1 (fr) | 1984-06-29 |
| CH657136A5 (de) | 1986-08-15 |
| DK593983A (da) | 1984-06-24 |
| SE454698B (sv) | 1988-05-24 |
| FR2538392B1 (fr) | 1987-01-16 |
| AU558600B2 (en) | 1987-02-05 |
| DK593983D0 (da) | 1983-12-22 |
| FI834698A7 (fi) | 1984-06-24 |
| AT385036B (de) | 1988-02-10 |
| FI834698A0 (fi) | 1983-12-20 |
| IL70522A (en) | 1986-02-28 |
| SE8307133L (sv) | 1984-06-24 |
| SE8307133D0 (sv) | 1983-12-22 |
| NL8304340A (nl) | 1984-07-16 |
| IT1194521B (it) | 1988-09-22 |
| AU2252583A (en) | 1984-06-28 |
| IT8324207A0 (it) | 1983-12-16 |
| US4522944A (en) | 1985-06-11 |
| SU1297731A3 (ru) | 1987-03-15 |
| DE3346223A1 (de) | 1984-06-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA1211440A (en) | Carboxamido-derivatives of 5h-1,3,4-thiadiazolo ¬3, 2-a| pyrimidines and process for their preparation | |
| KR101443795B1 (ko) | 항균성 조성물 | |
| AU2008334427B2 (en) | Antibacterial condensed thiazoles | |
| FI96857C (fi) | Menetelmä valmistaa farmakologisesti käyttökelpoista tiatsoliyhdistettä | |
| US8362037B2 (en) | 2-aminopyridine analogs as glucokinase activators | |
| EP1812440B1 (en) | Pyrazolo[1,5-a]pyrimidines useful as inhibitors of protein kinases | |
| CA1192546A (en) | Substituted 1h-pyrazolo¬1,5-a|pyrimidines and process for their preparation | |
| Segawa et al. | Studies on pyridonecarboxylic acids. 1. Synthesis and antibacterial evaluation of 7-substituted-6-halo-4-oxo-4H-[1, 3] thiazeto [3, 2-a] quinoline-3-carboxylic acids | |
| EP1986645A1 (en) | Glucokinase activators | |
| CA2137976A1 (en) | Thienothiazine derivatives | |
| AU2010336386A1 (en) | Aminopyrimidine kinase inhibitors | |
| EP2049503B1 (en) | Quinazoline and pyridopyrimidine derivatives as p38 kinase inhibitors | |
| EP2013204A2 (en) | 2-aminopyridine analogs as glucokinase activators | |
| WO2010135014A1 (en) | Tri-cyclic pyrazolopyridine kinase inhibitors | |
| US8481544B2 (en) | Antibacterial compositions | |
| WO2010096389A1 (en) | Tetrahydrothiazolopyridine inhibitors of phosphatidylinositol 3-kinase | |
| CA1218656A (en) | Pyridothienotriazines | |
| CA1211439A (en) | Substituted 1,3,4-thiadiazolo¬3,2-a|pyrimidines and process for their preparation | |
| GB2132200A (en) | Carboxamido-derivatives of 5H-1,3,4-thiadiazolo[3,2-a]-pyrimidines and process for their preparation | |
| AU2012200669B2 (en) | Antibacterial compositions | |
| GB2116971A (en) | 1H-pyrazolo [1,5-a] pyrimidines | |
| JPS59139389A (ja) | ５Ｈ−１，３，４−チアジアゾロ〔３，２−ａ〕ピリミジンのカルボキサミド誘導体およびそれらの製法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKEX | Expiry |