AU558600B2 - Carboxamido derivatives of 5h-1,3,4-thiadiazolo(3,2-alpha) pyrimidines and processes for their preparation - Google Patents

Carboxamido derivatives of 5h-1,3,4-thiadiazolo(3,2-alpha) pyrimidines and processes for their preparation

Info

Publication number
AU558600B2
AU558600B2 AU22525/83A AU2252583A AU558600B2 AU 558600 B2 AU558600 B2 AU 558600B2 AU 22525/83 A AU22525/83 A AU 22525/83A AU 2252583 A AU2252583 A AU 2252583A AU 558600 B2 AU558600 B2 AU 558600B2
Authority
AU
Australia
Prior art keywords
thiadiazolo
pyrimidines
alpha
processes
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU22525/83A
Other languages
English (en)
Other versions
AU2252583A (en
Inventor
Ada Buttinoni
Gianfederico Doria
Carlo Passarotti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838329746A external-priority patent/GB8329746D0/en
Application filed by Farmitalia Carlo Erba SRL filed Critical Farmitalia Carlo Erba SRL
Publication of AU2252583A publication Critical patent/AU2252583A/en
Application granted granted Critical
Publication of AU558600B2 publication Critical patent/AU558600B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
    • C07D285/125—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
    • C07D285/135—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU22525/83A 1982-12-23 1983-12-19 Carboxamido derivatives of 5h-1,3,4-thiadiazolo(3,2-alpha) pyrimidines and processes for their preparation Ceased AU558600B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB8236642 1982-12-23
GB8236642 1982-12-23
GB838329746A GB8329746D0 (en) 1983-11-08 1983-11-08 Carboxamido-derivatives
GB8329746 1983-11-08

Publications (2)

Publication Number Publication Date
AU2252583A AU2252583A (en) 1984-06-28
AU558600B2 true AU558600B2 (en) 1987-02-05

Family

ID=26284768

Family Applications (1)

Application Number Title Priority Date Filing Date
AU22525/83A Ceased AU558600B2 (en) 1982-12-23 1983-12-19 Carboxamido derivatives of 5h-1,3,4-thiadiazolo(3,2-alpha) pyrimidines and processes for their preparation

Country Status (15)

Country Link
US (1) US4522944A (enExample)
AT (1) AT385036B (enExample)
AU (1) AU558600B2 (enExample)
CA (1) CA1211440A (enExample)
CH (1) CH657136A5 (enExample)
DE (1) DE3346223A1 (enExample)
DK (1) DK593983A (enExample)
FI (1) FI834698A7 (enExample)
FR (1) FR2538392B1 (enExample)
GR (1) GR79479B (enExample)
IL (1) IL70522A (enExample)
IT (1) IT1194521B (enExample)
NL (1) NL8304340A (enExample)
SE (1) SE454698B (enExample)
SU (1) SU1297731A3 (enExample)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3702758A1 (de) * 1987-01-30 1988-09-29 Hoechst Ag Substituierte 3-phenyl-7h-thiazolo (3,2-b) (1,2,4) triazin-7-one, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung, sowie einige bei der herstellung der genannten verbindungen gebildete zwischenprodukte
JP5567349B2 (ja) 2007-03-12 2014-08-06 イントラ−セルラー・セラピーズ・インコーポレイテッド 置換ヘテロ環縮合ガンマ−カルボリンの合成
US11053245B2 (en) 2012-04-14 2021-07-06 Intra-Cellular Therapies, Inc. Methods
PL2968320T3 (pl) 2013-03-15 2021-05-17 Intra-Cellular Therapies, Inc. Związki organiczne
KR102373288B1 (ko) 2013-12-03 2022-03-10 인트라-셀룰라 써래피스, 인코퍼레이티드. 신규한 방법
BR112016023162B1 (pt) 2014-04-04 2022-11-29 Intra-Cellular Therapies, Inc Compostos orgânicos gama-carbolinas, composições farmacêuticas compreendendo os ditos compostos e uso dos mesmos no tratamento ou na profilaxia de transtornos de sistema nervoso central
JP2017509677A (ja) 2014-04-04 2017-04-06 イントラ−セルラー・セラピーズ・インコーポレイテッドＩｎｔｒａ−Ｃｅｌｌｕｌａｒ Ｔｈｅｒａｐｉｅｓ， Ｉｎｃ． 有機化合物
IL296884B2 (en) 2016-01-26 2024-05-01 Intra Cellular Therapies Inc Condensed heterocyclic converted gamma carbonyls for use in the treatment of central nervous system disorders
JP2019510039A (ja) 2016-03-28 2019-04-11 イントラ−セルラー・セラピーズ・インコーポレイテッドＩｎｔｒａ−Ｃｅｌｌｕｌａｒ Ｔｈｅｒａｐｉｅｓ， Ｉｎｃ． 新規組成物および方法
JP6997718B2 (ja) 2016-03-28 2022-01-18 イントラ－セルラー・セラピーズ・インコーポレイテッド 新規共結晶
WO2017172784A1 (en) 2016-03-28 2017-10-05 Intra-Cellular Therapies, Inc. Novel salts and crystals
WO2018071233A1 (en) 2016-10-12 2018-04-19 Intra-Cellular Therapies, Inc. Amorphous solid dispersions
WO2018126140A1 (en) 2016-12-29 2018-07-05 Intra-Cellular Therapies, Inc. Organic compounds
WO2018126143A1 (en) 2016-12-29 2018-07-05 Intra-Cellular Therapies, Inc. Organic compounds
CN116327770B (zh) 2017-03-24 2025-10-31 细胞内治疗公司 新组合物和方法
CA3071119A1 (en) 2017-07-26 2019-01-31 Intra-Cellular Therapies, Inc. Substituted heterocycle fused gamma-carbolines for treatment or prophylaxis of central nervous system disorders
AU2018307480B2 (en) 2017-07-26 2023-11-23 Intra-Cellular Therapies, Inc. Organic compounds
CA3094949A1 (en) 2018-03-23 2019-09-26 Intra-Cellular Therapies, Inc. Deuterated heterocycle fused gamma-carbolines
CA3102848A1 (en) 2018-06-06 2019-12-12 Intra-Cellular Therapies, Inc. Novel salts and crystals
MX2020013335A (es) 2018-06-08 2021-05-27 Intra Cellular Therapies Inc Metodos novedosos.
AU2019287460B2 (en) 2018-06-11 2024-02-15 Intra-Cellular Therapies, Inc. Substituted heterocycle fused gamma-carbolines synthesis
US12144808B2 (en) 2018-08-29 2024-11-19 Intra-Cellular Therapies, Inc. Compositions and methods
AU2019331490B2 (en) 2018-08-31 2025-04-24 Intra-Cellular Therapies, Inc. Novel methods
MX2021002322A (es) 2018-08-31 2021-04-28 Intra Cellular Therapies Inc Nuevos metodos.
CA3141223A1 (en) 2019-07-07 2021-01-14 Sharon Mates Novel methods
EP4072554A4 (en) 2019-12-11 2023-12-20 Intra-Cellular Therapies, Inc. ORGANIC COMPOUND
US12414948B2 (en) 2022-05-18 2025-09-16 Intra-Cellular Therapies, Inc. Methods

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5129981B2 (enExample) * 1973-07-17 1976-08-28
GB1568962A (en) * 1975-10-31 1980-06-11 Beecham Group Ltd Reparation and compositions containing them (heterocyclic-carbonylamino)pencillins methods for their p
JPS55115889A (en) * 1979-02-28 1980-09-06 Teijin Ltd 6-carbamoylthiazolo 3,2-a pyrimidine derivative and its preparation
JPS57142989A (en) * 1981-02-27 1982-09-03 Dai Ichi Seiyaku Co Ltd Thiazolopyrimidine derivative

Also Published As

Publication number Publication date
GR79479B (enExample) 1984-10-30
ATA438383A (de) 1987-07-15
IL70522A0 (en) 1984-03-30
FR2538392A1 (fr) 1984-06-29
CH657136A5 (de) 1986-08-15
DK593983A (da) 1984-06-24
SE454698B (sv) 1988-05-24
FR2538392B1 (fr) 1987-01-16
DK593983D0 (da) 1983-12-22
FI834698A7 (fi) 1984-06-24
CA1211440A (en) 1986-09-16
AT385036B (de) 1988-02-10
FI834698A0 (fi) 1983-12-20
IL70522A (en) 1986-02-28
SE8307133L (sv) 1984-06-24
SE8307133D0 (sv) 1983-12-22
NL8304340A (nl) 1984-07-16
IT1194521B (it) 1988-09-22
AU2252583A (en) 1984-06-28
IT8324207A0 (it) 1983-12-16
US4522944A (en) 1985-06-11
SU1297731A3 (ru) 1987-03-15
DE3346223A1 (de) 1984-06-28

Similar Documents

Publication Publication Date Title
AU558600B2 (en) Carboxamido derivatives of 5h-1,3,4-thiadiazolo(3,2-alpha) pyrimidines and processes for their preparation
AU557300B2 (en) Substituted 1h-pyrazolo(1,5-alpha)pyrimidines and processes for their preparation
AU553708B2 (en) Alkylimidazo(1,2-c)pyrazolo(3,4-e)pyrimidines
AU549161B2 (en) Preparation of 2,3-dichloro-5-trichloromethyl-pyridine
AU557042B2 (en) Crystallographic modification of pigment red 53:1
GB2103608B (en) Substituted thiazolo(3,2-a)pyrimidines and process for their preparation
AU1661383A (en) Locking of two screw elements
GB2114129B (en) Substituted 1,3,4-thiadiazolo(3,2-a) pyrimidines and process for their preparation
AU548640B2 (en) Preparation of 5,6,7,7alpha-tetrahydro-4h-thieno(3,2-c) pyridin-2-ones
AU7038687A (en) Fitting for releasable connection of two components
AU8652282A (en) Preparation of 4-aminobutyramide
IL74141A (en) Preparation of aryl substituted pyrido(1,4)benzodiazepines
ZA824797B (en) Substituted thiazolo(3,2-a)pyrimidines and process for their preparation
AU557360B2 (en) Substituted ethenyl derivatives of 1h-pyrazolo (1,5-alpha) pyrimidine
AU566580B2 (en) Preparation of 1-azidoaldoses
AU6748881A (en) Preparation of 5-cyano-(3,4-bipyridin)-6(1h)-one
ZA839105B (en) Carboxamido-derivatives of 5h-1,3,4-thiadiazolo(3,2-a)pyrimidines and process for their preparation
AU565857B2 (en) 216-bis-diethanocamino 4,8-dipiperi dino-pyrimido (5,4-d) pyrimidine composition
AU550553B2 (en) Preparation of 5,6-dihydro-2-methyl-n-phenyl-1,4- oxathiin-3-carboxamide
AU533574B1 (en) Preparation of fluorobenzophenones
AU2766484A (en) Preparation of aminoalkylureas
GB2078224B (en) The preparation of indolo(2'3';3'4)-pyrido-(2,1-b)quinazolin-5-ones
AU547822B2 (en) Preparation of 2,4-diamino-5-(3:,4,5:-tri-methoxybenzyl) pyrimidine
AU587309B2 (en) Process for the preparation of herbicides
AU587309C (en) Process for the preparation of herbicides