AU558600B2 - Carboxamido derivatives of 5h-1,3,4-thiadiazolo(3,2-alpha) pyrimidines and processes for their preparation - Google Patents

Carboxamido derivatives of 5h-1,3,4-thiadiazolo(3,2-alpha) pyrimidines and processes for their preparation

Info

Publication number
AU558600B2
AU558600B2 AU22525/83A AU2252583A AU558600B2 AU 558600 B2 AU558600 B2 AU 558600B2 AU 22525/83 A AU22525/83 A AU 22525/83A AU 2252583 A AU2252583 A AU 2252583A AU 558600 B2 AU558600 B2 AU 558600B2
Authority
AU
Australia
Prior art keywords
thiadiazolo
pyrimidines
alpha
processes
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU22525/83A
Other languages
English (en)
Other versions
AU2252583A (en
Inventor
Ada Buttinoni
Gianfederico Doria
Carlo Passarotti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838329746A external-priority patent/GB8329746D0/en
Application filed by Farmitalia Carlo Erba SRL filed Critical Farmitalia Carlo Erba SRL
Publication of AU2252583A publication Critical patent/AU2252583A/en
Application granted granted Critical
Publication of AU558600B2 publication Critical patent/AU558600B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
    • C07D285/125—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
    • C07D285/135—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU22525/83A 1982-12-23 1983-12-19 Carboxamido derivatives of 5h-1,3,4-thiadiazolo(3,2-alpha) pyrimidines and processes for their preparation Ceased AU558600B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB8236642 1982-12-23
GB8236642 1982-12-23
GB838329746A GB8329746D0 (en) 1983-11-08 1983-11-08 Carboxamido-derivatives
GB8329746 1983-11-08

Publications (2)

Publication Number Publication Date
AU2252583A AU2252583A (en) 1984-06-28
AU558600B2 true AU558600B2 (en) 1987-02-05

Family

ID=26284768

Family Applications (1)

Application Number Title Priority Date Filing Date
AU22525/83A Ceased AU558600B2 (en) 1982-12-23 1983-12-19 Carboxamido derivatives of 5h-1,3,4-thiadiazolo(3,2-alpha) pyrimidines and processes for their preparation

Country Status (15)

Country Link
US (1) US4522944A (enExample)
AT (1) AT385036B (enExample)
AU (1) AU558600B2 (enExample)
CA (1) CA1211440A (enExample)
CH (1) CH657136A5 (enExample)
DE (1) DE3346223A1 (enExample)
DK (1) DK593983A (enExample)
FI (1) FI834698A7 (enExample)
FR (1) FR2538392B1 (enExample)
GR (1) GR79479B (enExample)
IL (1) IL70522A (enExample)
IT (1) IT1194521B (enExample)
NL (1) NL8304340A (enExample)
SE (1) SE454698B (enExample)
SU (1) SU1297731A3 (enExample)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3702758A1 (de) * 1987-01-30 1988-09-29 Hoechst Ag Substituierte 3-phenyl-7h-thiazolo (3,2-b) (1,2,4) triazin-7-one, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung, sowie einige bei der herstellung der genannten verbindungen gebildete zwischenprodukte
CN101796051B (zh) * 2007-03-12 2013-11-06 细胞内治疗公司 与取代的杂环稠合的γ-咔啉的合成
EP2836211B1 (en) 2012-04-14 2019-03-20 Intra-Cellular Therapies, Inc. Treatment of PTSD and impulse control disorders
PT2968320T (pt) 2013-03-15 2021-01-28 Intra Cellular Therapies Inc Compostos orgânicos
IL321987A (en) 2013-12-03 2025-09-01 Intra Cellular Therapies Inc A long-acting injectable preparation containing polymeric microspheres of modified compressed gamma-carboline heterocyclic compounds or a sustained-release pharmaceutical preparation containing these compounds for use in the treatment of bipolar I and/or bipolar II disorders
WO2015154025A1 (en) 2014-04-04 2015-10-08 Intra-Cellular Therapies, Inc. Organic compounds
CN106456638A (zh) 2014-04-04 2017-02-22 细胞内治疗公司 有机化合物
CA3011983A1 (en) 2016-01-26 2017-08-03 Intra-Cellular Therapies, Inc. Substituted heterocycle fused gamma-carbolines
US10682354B2 (en) 2016-03-28 2020-06-16 Intra-Cellular Therapies, Inc. Compositions and methods
JP6997718B2 (ja) 2016-03-28 2022-01-18 イントラ－セルラー・セラピーズ・インコーポレイテッド 新規共結晶
JP2019513143A (ja) 2016-03-28 2019-05-23 イントラ−セルラー・セラピーズ・インコーポレイテッドＩｎｔｒａ−Ｃｅｌｌｕｌａｒ Ｔｈｅｒａｐｉｅｓ， Ｉｎｃ． 新規塩類および結晶
US11331316B2 (en) 2016-10-12 2022-05-17 Intra-Cellular Therapies, Inc. Amorphous solid dispersions
WO2018126140A1 (en) 2016-12-29 2018-07-05 Intra-Cellular Therapies, Inc. Organic compounds
WO2018126143A1 (en) 2016-12-29 2018-07-05 Intra-Cellular Therapies, Inc. Organic compounds
WO2018175969A1 (en) 2017-03-24 2018-09-27 Intra-Cellular Therapies, Inc. Novel compositions and methods
IL272252B2 (en) 2017-07-26 2024-03-01 Intra Cellular Therapies Inc Derivatives of substituted heterocycle fused gamma-carbolines, pharmaceutical compositions comnprising them and their use in treatment
KR102899502B1 (ko) 2017-07-26 2025-12-11 인트라-셀룰라 써래피스, 인코퍼레이티드. 유기 화합물
MX2020009928A (es) 2018-03-23 2021-01-08 Intra Cellular Therapies Inc Compuestos organicos.
EP3628007B1 (en) 2018-06-06 2023-05-03 Intra-Cellular Therapies, Inc. Novel salts and crystals
WO2019237037A1 (en) 2018-06-08 2019-12-12 Intra-Cellular Therapies, Inc. Novel methods
EP3609891B1 (en) 2018-06-11 2026-02-11 Intra-Cellular Therapies, Inc. Substituted heterocycle fused gamma-carbolines synthesis
WO2020047241A1 (en) 2018-08-29 2020-03-05 Intra-Cellular Therapies, Inc. Novel compositions and methods
KR20210052472A (ko) 2018-08-31 2021-05-10 인트라-셀룰라 써래피스, 인코퍼레이티드. 신규한 방법
WO2020047407A1 (en) 2018-08-31 2020-03-05 Intra-Cellular Therapies, Inc. Novel methods
BR112022000231A2 (pt) 2019-07-07 2022-02-22 Intra Cellular Therapies Inc Novos métodos
JP7261942B2 (ja) 2019-12-11 2023-04-20 イントラ－セルラー・セラピーズ・インコーポレイテッド 有機化合物
US12414948B2 (en) 2022-05-18 2025-09-16 Intra-Cellular Therapies, Inc. Methods

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5129981B2 (enExample) * 1973-07-17 1976-08-28
GB1568962A (en) * 1975-10-31 1980-06-11 Beecham Group Ltd Reparation and compositions containing them (heterocyclic-carbonylamino)pencillins methods for their p
JPS55115889A (en) * 1979-02-28 1980-09-06 Teijin Ltd 6-carbamoylthiazolo 3,2-a pyrimidine derivative and its preparation
JPS57142989A (en) * 1981-02-27 1982-09-03 Dai Ichi Seiyaku Co Ltd Thiazolopyrimidine derivative

Also Published As

Publication number Publication date
IT8324207A0 (it) 1983-12-16
IL70522A (en) 1986-02-28
ATA438383A (de) 1987-07-15
CA1211440A (en) 1986-09-16
AU2252583A (en) 1984-06-28
FI834698A7 (fi) 1984-06-24
FR2538392B1 (fr) 1987-01-16
SE8307133L (sv) 1984-06-24
SE454698B (sv) 1988-05-24
CH657136A5 (de) 1986-08-15
GR79479B (enExample) 1984-10-30
FR2538392A1 (fr) 1984-06-29
US4522944A (en) 1985-06-11
SE8307133D0 (sv) 1983-12-22
AT385036B (de) 1988-02-10
SU1297731A3 (ru) 1987-03-15
DK593983A (da) 1984-06-24
IT1194521B (it) 1988-09-22
DE3346223A1 (de) 1984-06-28
IL70522A0 (en) 1984-03-30
FI834698A0 (fi) 1983-12-20
DK593983D0 (da) 1983-12-22
NL8304340A (nl) 1984-07-16

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