CA1205471A - Dihydropyridines - Google Patents

Dihydropyridines

Info

Publication number
CA1205471A
CA1205471A CA000427276A CA427276A CA1205471A CA 1205471 A CA1205471 A CA 1205471A CA 000427276 A CA000427276 A CA 000427276A CA 427276 A CA427276 A CA 427276A CA 1205471 A CA1205471 A CA 1205471A
Authority
CA
Canada
Prior art keywords
compound
formula
straight
carbon atoms
alkyl group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000427276A
Other languages
English (en)
French (fr)
Inventor
Bengt R. Ljung
Peder B. Berntsson
Stig A. I. Carlsson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hassle AB
Original Assignee
Hassle AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hassle AB filed Critical Hassle AB
Application granted granted Critical
Publication of CA1205471A publication Critical patent/CA1205471A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
CA000427276A 1982-05-21 1983-05-03 Dihydropyridines Expired CA1205471A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE8203176.6 1982-05-21
SE8203176 1982-05-21

Publications (1)

Publication Number Publication Date
CA1205471A true CA1205471A (en) 1986-06-03

Family

ID=20346867

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000427276A Expired CA1205471A (en) 1982-05-21 1983-05-03 Dihydropyridines

Country Status (19)

Country Link
EP (1) EP0095451A3 (enExample)
JP (1) JPS58210063A (enExample)
KR (1) KR900006682B1 (enExample)
AU (1) AU1464583A (enExample)
CA (1) CA1205471A (enExample)
DD (2) DD209816A5 (enExample)
DK (1) DK223683A (enExample)
ES (3) ES8503655A1 (enExample)
FI (1) FI80677C (enExample)
GB (1) GB2120668B (enExample)
GR (1) GR78566B (enExample)
HU (2) HU188342B (enExample)
IL (1) IL68524A0 (enExample)
IS (1) IS1381B6 (enExample)
MW (1) MW1783A1 (enExample)
NO (1) NO163327C (enExample)
NZ (1) NZ204283A (enExample)
PT (1) PT76733B (enExample)
ZA (1) ZA833112B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3600594A1 (de) * 1986-01-11 1987-07-16 Bayer Ag Methioninsubstituierte 1,4-dihydropyridine, verfahren zur herstellung und ihre verwendung
US4814455A (en) * 1986-04-16 1989-03-21 Bristol-Myers Company Dihydro-3,5-dicarboxylates
JPS63112560A (ja) * 1986-10-29 1988-05-17 Green Cross Corp:The ジヒドロピリジン誘導体
US5310917A (en) * 1991-09-13 1994-05-10 Merck & Co., Inc. Process for the preparation of 4-substituted-1,4-dihydropydrines

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2747513A1 (de) * 1977-10-22 1979-05-03 Bayer Ag Dihydropyridine mit schwefelhaltigen estergruppierungen
EP0002007B1 (de) * 1977-11-11 1982-07-28 Ciba-Geigy Ag Neue Pyridindicarbonsäureesterderivate und ihre Gemische mit metallhaltigen Stabilisatoren sowie ihre Verwendung zur Stabilisierung von chlorhaltigen Thermoplasten
US4285955A (en) * 1978-10-31 1981-08-25 Bayer Aktiengesellschaft 1,4-Dihydropyridinecarboxylic acids

Also Published As

Publication number Publication date
ES535215A0 (es) 1985-05-01
MW1783A1 (en) 1985-06-12
IL68524A0 (en) 1983-07-31
GB2120668B (en) 1985-08-29
IS1381B6 (is) 1989-08-28
NZ204283A (en) 1985-11-08
DK223683D0 (da) 1983-05-19
FI80677B (fi) 1990-03-30
KR900006682B1 (ko) 1990-09-17
ES522570A0 (es) 1985-03-16
AU1464583A (en) 1983-11-24
JPS58210063A (ja) 1983-12-07
DK223683A (da) 1983-11-22
FI831778A0 (fi) 1983-05-19
FI80677C (fi) 1990-07-10
DD216009A5 (de) 1984-11-28
NO831806L (no) 1983-11-22
FI831778L (fi) 1983-11-22
NO163327B (no) 1990-01-29
ZA833112B (en) 1983-12-28
PT76733B (en) 1986-03-27
GB8314034D0 (en) 1983-06-29
ES8503655A1 (es) 1985-03-16
ES8504712A1 (es) 1985-05-01
KR840004723A (ko) 1984-10-24
NO163327C (no) 1990-05-09
EP0095451A2 (en) 1983-11-30
HU193786B (en) 1987-11-30
ES8504713A1 (es) 1985-05-01
DD209816A5 (de) 1984-05-23
GR78566B (enExample) 1984-09-27
HU188342B (en) 1986-04-28
ES535216A0 (es) 1985-05-01
PT76733A (en) 1983-06-01
GB2120668A (en) 1983-12-07
EP0095451A3 (en) 1984-08-29
IS2809A7 (is) 1983-11-22

Similar Documents

Publication Publication Date Title
US4264611A (en) 2,6-Dimethyl-4-2,3-disubstituted phenyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid-3,5-asymmetric diesters having hypotensive properties, as well as method for treating hypertensive conditions and pharmaceutical preparations containing same
HU187868B (en) Process for producing dihydropyridine derivatives
CA1306261C (fr) 1,4-dihydropyridines, leur procede de preparation et leur application comme medicaments
EP0106462B1 (en) Dihydropyridines
FR2562892A1 (fr) Nouveaux dihydropyridinyldicarboxylates amides et esters, utilisation de ces composes comme medicament, compositions pharmaceutiques comprenant de tels composes et procede pour la preparation de tels composes
SK281467B6 (sk) Krátko pôsobiace dihydropyridíny, spôsoby ich prípravy, farmaceutické prípravky s ich obsahom a ich použitie
JPH02502823A (ja) １，４―ジヒドロピリジン―エナンチオマーおよびその製法
EP0031801A2 (en) 6-Substituted 4-(2',3'-dichlorophenyl)-2-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid diesters having hypotensive properties as well as process for their preparation and pharmaceutical preparations containing same
JPS6360755B2 (enExample)
CA1205471A (en) Dihydropyridines
WO2009092301A1 (zh) 二氢吡啶类钙拮抗剂化合物及其制备方法与医药用途
HU194543B (en) Process for preparing 1,4-dihydro-pyridine-hydroxy-amine derivatives and pharmaceutical compositions comprising the same as active substance
KR900006116B1 (ko) 신규 디히드로피리딘의 제조 방법
EP0194751A1 (en) Dihydropyridine alkanol amines, process for their preparation and pharmaceutical compositions containing them
EP0249174B1 (en) 1,4-dihydropyridine derivatives, processes for their preparation and pharmaceutical compositions containing same
US4824855A (en) 1,4-dihydropyridine derivatives
JPH0155268B2 (enExample)
SE442298B (sv) 2,6-dimetyl-4-(2,3-diklorfenyl)-1,4-dihydropyridin-3,5-dikarboxylsyra-3-metylester-5-etylester i optisk aktiv form
MC1675A1 (fr) Dérivés de dihydropyridine
NO167455B (no) Mellomprodukter
JPS5852286A (ja) 新規なジヒドロピリジン化合物
JPS6092265A (ja) ２−ヒドロキシアルキル−１．４−ジヒドロピリジン−３．５−ジカルボン酸ジエステル誘導体の新規な製造法
IE55337B1 (en) Dihydropyridyl cyclic imidate esters
CS241038B2 (cs) Způsob výroby 3-methyl-5-ethylesteru kyseliny 2,6-dimethyl-4-(2,3-dichlorfenyl)-l,4-dihydropyridin-3,S- -dikarboxylové

Legal Events

Date Code Title Description
MKEX Expiry