CA1181069A - Procede de preparation de (trialcoxybenzyl)-1 piperazines - Google Patents

Procede de preparation de (trialcoxybenzyl)-1 piperazines

Info

Publication number
CA1181069A
CA1181069A CA000389487A CA389487A CA1181069A CA 1181069 A CA1181069 A CA 1181069A CA 000389487 A CA000389487 A CA 000389487A CA 389487 A CA389487 A CA 389487A CA 1181069 A CA1181069 A CA 1181069A
Authority
CA
Canada
Prior art keywords
piperazinone
benzyl
phase
solvent
piperazine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000389487A
Other languages
English (en)
French (fr)
Inventor
Gilbert Regnier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Science Union et Cie
Original Assignee
Science Union et Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Science Union et Cie filed Critical Science Union et Cie
Application granted granted Critical
Publication of CA1181069A publication Critical patent/CA1181069A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA000389487A 1980-11-06 1981-11-05 Procede de preparation de (trialcoxybenzyl)-1 piperazines Expired CA1181069A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR80.23678 1980-11-06
FR8023678A FR2493316A1 (fr) 1980-11-06 1980-11-06 Nouveau procede de preparation des (trialcoxy benzyl)-1 piperazines et notamment de la (trimethoxy-2', 3', 4' benzyl)-1 piperazine

Publications (1)

Publication Number Publication Date
CA1181069A true CA1181069A (fr) 1985-01-15

Family

ID=9247720

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000389487A Expired CA1181069A (fr) 1980-11-06 1981-11-05 Procede de preparation de (trialcoxybenzyl)-1 piperazines

Country Status (16)

Country Link
JP (1) JPS57108086A (es)
AU (1) AU546225B2 (es)
BE (1) BE891012A (es)
CA (1) CA1181069A (es)
CH (1) CH651031A5 (es)
DE (1) DE3144235A1 (es)
EG (1) EG15454A (es)
ES (1) ES8302679A1 (es)
FR (1) FR2493316A1 (es)
GR (1) GR75036B (es)
IT (1) IT1142928B (es)
LU (1) LU83738A1 (es)
MA (1) MA19322A1 (es)
MX (1) MX6973E (es)
OA (1) OA06939A (es)
PT (1) PT73935B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH650176A5 (fr) * 1982-08-23 1985-07-15 Daussan & Co Dispositif pour la coulee du metal fondu.
FR2661176B1 (fr) * 1990-04-20 1992-06-12 Adir Nouveau procede de preparation de la 1-(2,3,4-trimethoxybenzyl) piperazine en amination reductive.
FR2703048B1 (fr) * 1993-03-24 1996-01-05 Adir Nouveaux composes n-benzylpiperazine, leur procede de preparation et les compositions pharmaceutiques les renfermant.
CN100413854C (zh) * 2004-06-29 2008-08-27 北京德众万全药物技术开发有限公司 一种曲美他嗪及其药用盐的制备方法
CN102993122B (zh) * 2012-12-24 2015-03-04 武汉武药制药有限公司 盐酸曲美他嗪的合成新路线

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2438725A1 (de) * 1974-08-12 1976-02-26 Knoll Ag Piperazinderivate

Also Published As

Publication number Publication date
DE3144235A1 (de) 1982-06-24
PT73935B (fr) 1983-11-30
ES506814A0 (es) 1983-02-01
FR2493316A1 (fr) 1982-05-07
FR2493316B1 (es) 1983-04-15
AU546225B2 (en) 1985-08-22
PT73935A (fr) 1981-12-01
MX6973E (es) 1987-01-13
MA19322A1 (fr) 1982-07-01
JPS57108086A (en) 1982-07-05
BE891012A (fr) 1982-05-05
CH651031A5 (fr) 1985-08-30
ES8302679A1 (es) 1983-02-01
EG15454A (en) 1985-12-31
LU83738A1 (fr) 1982-06-30
GR75036B (es) 1984-07-12
IT1142928B (it) 1986-10-15
OA06939A (fr) 1983-07-31
AU7712181A (en) 1982-05-13
IT8149630A0 (it) 1981-11-04

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Legal Events

Date Code Title Description
MKEX Expiry