CA1164458A - Process for the preparation of 2,4-diamino-5-(3',4', 5'-trimethoxybenzyl)pyrimidine - Google Patents
Process for the preparation of 2,4-diamino-5-(3',4', 5'-trimethoxybenzyl)pyrimidineInfo
- Publication number
- CA1164458A CA1164458A CA000405973A CA405973A CA1164458A CA 1164458 A CA1164458 A CA 1164458A CA 000405973 A CA000405973 A CA 000405973A CA 405973 A CA405973 A CA 405973A CA 1164458 A CA1164458 A CA 1164458A
- Authority
- CA
- Canada
- Prior art keywords
- formula
- beta
- alpha
- diethylene glycol
- guanidine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
- C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Liquid Crystal Substances (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU811868A HU186413B (en) | 1981-06-26 | 1981-06-26 | Process for producing 2,4-diamino-5-bracket-3-comma above,4-comma above,5-comma above-trimethoxy-benzyl-bracket closed-pyrimidine |
HU1868/81 | 1981-06-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA1164458A true CA1164458A (en) | 1984-03-27 |
Family
ID=10956590
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA000405973A Expired CA1164458A (en) | 1981-06-26 | 1982-06-25 | Process for the preparation of 2,4-diamino-5-(3',4', 5'-trimethoxybenzyl)pyrimidine |
Country Status (22)
Country | Link |
---|---|
JP (1) | JPS5838265A (ru) |
AT (1) | AT385033B (ru) |
AU (1) | AU547822B2 (ru) |
BE (1) | BE893609A (ru) |
CA (1) | CA1164458A (ru) |
CH (1) | CH651828A5 (ru) |
CS (1) | CS244907B2 (ru) |
DD (1) | DD202702A5 (ru) |
DK (1) | DK155668C (ru) |
ES (1) | ES8304948A1 (ru) |
FI (1) | FI76789C (ru) |
FR (1) | FR2508449B1 (ru) |
GB (1) | GB2106098B (ru) |
GR (1) | GR76158B (ru) |
HU (1) | HU186413B (ru) |
IE (1) | IE53347B1 (ru) |
IL (1) | IL66131A (ru) |
IT (1) | IT1190888B (ru) |
RO (1) | RO85316B (ru) |
SE (1) | SE451134B (ru) |
SU (1) | SU1147252A3 (ru) |
YU (1) | YU42264B (ru) |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1303727B (de) * | 1959-09-03 | 1976-02-05 | Ausscheidung aus: 14 45 176 The Wellcome Foundation Ltd., London | Alpha-Arylidensubstituierte Propioni-Irile |
NL122146C (ru) * | 1960-09-02 | |||
DE2635765C3 (de) * | 1976-08-09 | 1979-02-08 | Ludwig Heumann & Co Gmbh, 8500 Nuernberg | Verfahren zur Herstellung von 2,4-EMamino-5-(3',4'r5'-trimethoxybenzyl)-pyrimidin |
US4115650A (en) * | 1976-11-17 | 1978-09-19 | Hoffmann-La Roche Inc. | Process for preparing 2,4-diamino-5-(substituted benzyl)-pyrimidines |
DE2730467A1 (de) * | 1977-07-06 | 1979-01-18 | Basf Ag | Benzylpyrimidine, verfahren zu ihrer herstellung und diese enthaltende arzneimittel |
-
1981
- 1981-06-26 HU HU811868A patent/HU186413B/hu not_active IP Right Cessation
-
1982
- 1982-06-18 DK DK275682A patent/DK155668C/da not_active IP Right Cessation
- 1982-06-23 BE BE1/10542A patent/BE893609A/fr not_active IP Right Cessation
- 1982-06-23 SE SE8203913A patent/SE451134B/sv not_active IP Right Cessation
- 1982-06-24 CS CS824716A patent/CS244907B2/cs unknown
- 1982-06-24 SU SU823456105A patent/SU1147252A3/ru active
- 1982-06-24 RO RO107980A patent/RO85316B/ro unknown
- 1982-06-24 IT IT22034/82A patent/IT1190888B/it active
- 1982-06-24 FI FI822267A patent/FI76789C/fi not_active IP Right Cessation
- 1982-06-24 IL IL66131A patent/IL66131A/xx unknown
- 1982-06-24 GB GB08218309A patent/GB2106098B/en not_active Expired
- 1982-06-24 GR GR68559A patent/GR76158B/el unknown
- 1982-06-24 AT AT0244882A patent/AT385033B/de not_active IP Right Cessation
- 1982-06-24 DD DD82241053A patent/DD202702A5/de not_active IP Right Cessation
- 1982-06-25 YU YU1384/82A patent/YU42264B/xx unknown
- 1982-06-25 IE IE1521/82A patent/IE53347B1/en not_active IP Right Cessation
- 1982-06-25 AU AU85345/82A patent/AU547822B2/en not_active Ceased
- 1982-06-25 FR FR8211150A patent/FR2508449B1/fr not_active Expired
- 1982-06-25 CH CH3907/82A patent/CH651828A5/de not_active IP Right Cessation
- 1982-06-25 ES ES513481A patent/ES8304948A1/es not_active Expired
- 1982-06-25 CA CA000405973A patent/CA1164458A/en not_active Expired
- 1982-06-25 JP JP57109646A patent/JPS5838265A/ja active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US3341541A (en) | Processes and intermediates for pyrimidine derivatives | |
RU2017736C1 (ru) | 5,6-дигидро-2-(замещенный фенил)-1,2,4-триазин-3,5-(2н,4н)-дионы, обладающие противококсидиальной и коксидиостатической активностью | |
US4670559A (en) | 2-amino-4-cyclopropyl-1,3,5-triazines as intermediates for the production of herbicidally active N-(cyclopropyl-triazinyl)-N'-arylsulfonyl ureas | |
JPS6383079A (ja) | 2−クロル−5−クロルメチルチアゾールの製造法 | |
US4864026A (en) | Method of manufacturing N-alkyl-N'-methyl-alkyleneureas, particularly N,N'-d | |
FR2492383A1 (fr) | Halogenures d'ammonium spiro-quaternaire, leur procede de prepatation et leur utilisation dans un procede de production de n-(2-pyrimidinyl) piperazinyl-alkylazospiro-alcanediones | |
EP0079447B1 (en) | Deazapurine derivatives | |
CA1164458A (en) | Process for the preparation of 2,4-diamino-5-(3',4', 5'-trimethoxybenzyl)pyrimidine | |
JP5289331B2 (ja) | 4−アミノ−ピリミジンの合成 | |
CA1091673A (en) | Diamino-benzylpyrimidines | |
US4225721A (en) | Novel amidoxime derivatives | |
US3018305A (en) | Alpha-phenylben-zoyl-alpha-arylaminocarbinol derivatives | |
US4255574A (en) | Process for preparing 2,4-diamino-pyrimidines | |
KR100697737B1 (ko) | 5-[(4-클로로페닐)메틸]-2,2-디메틸시클로펜탄온의 제조방법 | |
US5543541A (en) | Method of preparing aryl triazolinones with trialkyl orthoacetates | |
GB1579859A (en) | Process for the production of 2,4-diamino-5-benzylpyrimidines | |
EP0067593A1 (en) | Process for the preparation of trimethoprim and novel intermediates for use therein | |
FI76790C (fi) | Foerfarande foer framstaellning av 2,4-diamino-5-(3',4',5'-trimetoxibensyl)pyrimidin. | |
US4786736A (en) | Preparation of diaziridines and products therefrom | |
US4789743A (en) | Process for the preparation of 2,4-diamino-5-benzylpyrimidines | |
SU1066997A1 (ru) | Новые гетероциклические триазаспиро-конденсированные системы | |
EP1359149B1 (en) | Process for preparing triazolopyrimidine derivatives | |
US6166259A (en) | Process for preparing a 1,1,1-trifluoro-2-aminoalkane | |
RU2089539C1 (ru) | Способ получения 2,5-n,n'-(диметиламинометил)-1,4-гидрохинона | |
RU2189970C1 (ru) | Способ получения бис-n,n'-(3,5-ди-трет-бутил-4-оксибензил)-метиламина |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MKEX | Expiry |