CA1149385A - 4-substituted imidazo [1,2-a] quinoxalines, and intermediates, and process for preparing the same - Google Patents
4-substituted imidazo [1,2-a] quinoxalines, and intermediates, and process for preparing the sameInfo
- Publication number
- CA1149385A CA1149385A CA000293972A CA293972A CA1149385A CA 1149385 A CA1149385 A CA 1149385A CA 000293972 A CA000293972 A CA 000293972A CA 293972 A CA293972 A CA 293972A CA 1149385 A CA1149385 A CA 1149385A
- Authority
- CA
- Canada
- Prior art keywords
- process according
- substituted
- carbon
- aliphatic
- chemical equivalent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA000423468A CA1164877A (en) | 1977-01-07 | 1983-03-11 | 1-(2-acyl-aminophenyl)imidazoles |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75764077A | 1977-01-07 | 1977-01-07 | |
| US757,640 | 1977-01-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1149385A true CA1149385A (en) | 1983-07-05 |
Family
ID=25048641
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000293972A Expired CA1149385A (en) | 1977-01-07 | 1977-12-28 | 4-substituted imidazo [1,2-a] quinoxalines, and intermediates, and process for preparing the same |
Country Status (19)
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE439308B (sv) * | 1978-08-02 | 1985-06-10 | Roussel Uclaf | Imidazo(1,2-a)kinoxaliner och farmaceutiska kompositioner derav |
| JPS5569567A (en) * | 1978-11-21 | 1980-05-26 | Eisai Co Ltd | Novel imidazole compound, and antidepressant containing the same |
| IT1209431B (it) * | 1980-11-28 | 1989-07-16 | Angeli Inst Spa | Imidazolilfenil amidine, processi per la loro preparazione e loro impiego farmaceutico, ed intermedi di preparazione. |
| DE3830054A1 (de) * | 1988-09-03 | 1990-03-15 | Boehringer Mannheim Gmbh | Phenylamide - verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel |
| JPH0349309U (US06811534-20041102-M00003.png) * | 1989-09-21 | 1991-05-14 | ||
| US6635626B1 (en) | 1997-08-25 | 2003-10-21 | Bristol-Myers Squibb Co. | Imidazoquinoxaline protein tyrosine kinase inhibitors |
| US6235740B1 (en) | 1997-08-25 | 2001-05-22 | Bristol-Myers Squibb Co. | Imidazoquinoxaline protein tyrosine kinase inhibitors |
| US6451796B1 (en) | 1997-11-11 | 2002-09-17 | Ono Pharmaceutical Co., Ltd. | Fused pyrazine compounds |
| ATE430149T1 (de) * | 1998-03-04 | 2009-05-15 | Bristol Myers Squibb Co | Heterocyclen substituierte imidazopyrazine als protein- tyrosin-kinase-inhibitoren |
| US6869956B2 (en) * | 2000-10-03 | 2005-03-22 | Bristol-Myers Squibb Company | Methods of treating inflammatory and immune diseases using inhibitors of IκB kinase (IKK) |
| EP1325009B1 (en) | 2000-10-03 | 2006-03-08 | Bristol-Myers Squibb Company | Amino-substituted tetracyclic compounds useful as anti-inflammatory agents and pharmaceutical compositions comprising same |
| WO2002060386A2 (en) * | 2001-02-01 | 2002-08-08 | Bristol-Myers Squibb Company | METHODS OF TREATING INFLAMMATORY AND IMMUNE DISEASES USING INHIBITORS OF IλB KINASE (IKK) |
| US20080076770A1 (en) * | 2006-09-25 | 2008-03-27 | Arete Therapeutics, Inc. | Soluble epoxide hydrolase inhibitors |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3541109A (en) * | 1968-06-25 | 1970-11-17 | Du Pont | 1-substituted imidazoles useful in acth reserve assay |
| US4011236A (en) * | 1968-09-09 | 1977-03-08 | Merck & Co., Inc. | N-(benzimidazol-2-yl)arylcarboxamides as ultraviolet (uv) light absorbers |
| GB1347493A (en) * | 1971-02-11 | 1974-02-27 | Aspro Nicholas Ltd | Benzazine derivatives |
| US3994893A (en) | 1975-11-03 | 1976-11-30 | E. R. Squibb & Sons, Inc. | 4-Amino derivatives of pyrozolo[1,5-a]quinoxaline-3-carboxylic acid and esters |
-
1977
- 1977-12-08 US US05/858,515 patent/US4160097A/en not_active Expired - Lifetime
- 1977-12-23 GR GR55051A patent/GR73168B/el unknown
- 1977-12-28 JP JP15758177A patent/JPS5387398A/ja active Granted
- 1977-12-28 CA CA000293972A patent/CA1149385A/en not_active Expired
-
1978
- 1978-01-03 BE BE184085A patent/BE862608A/xx not_active IP Right Cessation
- 1978-01-04 NL NL7800114A patent/NL7800114A/xx not_active Application Discontinuation
- 1978-01-04 DK DK004278A patent/DK157024C/da not_active IP Right Cessation
- 1978-01-04 FI FI780023A patent/FI64374C/fi not_active IP Right Cessation
- 1978-01-04 ZA ZA00780027A patent/ZA7827B/xx unknown
- 1978-01-05 LU LU78813A patent/LU78813A1/xx unknown
- 1978-01-05 SE SE7800138A patent/SE436359B/sv not_active IP Right Cessation
- 1978-01-05 DE DE19782800480 patent/DE2800480A1/de active Granted
- 1978-01-05 DE DE2858766A patent/DE2858766C2/de not_active Expired - Fee Related
- 1978-01-06 GB GB13335/79A patent/GB1579499A/en not_active Expired
- 1978-01-06 FR FR7800308A patent/FR2376858A1/fr active Granted
- 1978-01-06 YU YU21/78A patent/YU44663B/xx unknown
- 1978-01-06 CH CH15278A patent/CH636102A5/fr not_active IP Right Cessation
- 1978-01-06 GB GB492/78A patent/GB1579498A/en not_active Expired
- 1978-01-06 IE IE37/78A patent/IE46191B1/en unknown
- 1978-01-09 CS CS78169A patent/CS200232B2/cs unknown
- 1978-01-11 AU AU32331/78A patent/AU521807B2/en not_active Expired
-
1983
- 1983-01-18 CH CH27483A patent/CH640229A5/fr not_active IP Right Cessation
- 1983-02-21 SE SE8300945A patent/SE460477B/sv not_active IP Right Cessation
-
1986
- 1986-01-17 JP JP61006590A patent/JPS61171470A/ja active Granted
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKEX | Expiry |