CA1139305A - Derives de peptide - Google Patents

Derives de peptide

Info

Publication number
CA1139305A
CA1139305A CA000305645A CA305645A CA1139305A CA 1139305 A CA1139305 A CA 1139305A CA 000305645 A CA000305645 A CA 000305645A CA 305645 A CA305645 A CA 305645A CA 1139305 A CA1139305 A CA 1139305A
Authority
CA
Canada
Prior art keywords
ser
group
cys
formula
ala
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000305645A
Other languages
English (en)
Inventor
Lajos Z. Tarcsay
Bruno Kamber
Jaroslav Stanek
Gerhard Baschang
Albert Hartmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy Investments Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Investments Ltd filed Critical Ciba Geigy Investments Ltd
Application granted granted Critical
Publication of CA1139305A publication Critical patent/CA1139305A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/0606—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing heteroatoms not provided for by C07K5/06086 - C07K5/06139, e.g. Ser, Met, Cys, Thr
    • C07K5/06069—Ser-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/081—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1013—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA000305645A 1977-06-20 1978-06-16 Derives de peptide Expired CA1139305A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
LU77584 1977-06-20
LU77584 1977-06-20

Publications (1)

Publication Number Publication Date
CA1139305A true CA1139305A (fr) 1983-01-11

Family

ID=19728618

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000305645A Expired CA1139305A (fr) 1977-06-20 1978-06-16 Derives de peptide

Country Status (18)

Country Link
EP (1) EP0000330B1 (fr)
JP (2) JPS549224A (fr)
AT (1) AT364095B (fr)
AU (1) AU525005B2 (fr)
CA (1) CA1139305A (fr)
DD (1) DD139257A5 (fr)
DE (1) DE2860893D1 (fr)
DK (1) DK275178A (fr)
ES (3) ES470961A1 (fr)
FI (1) FI781933A (fr)
GR (1) GR71681B (fr)
IE (1) IE46957B1 (fr)
IL (1) IL54950A (fr)
NO (1) NO148921C (fr)
NZ (1) NZ187611A (fr)
PL (3) PL207766A1 (fr)
PT (1) PT68188A (fr)
ZA (1) ZA783504B (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5342977A (en) * 1991-12-19 1994-08-30 Ciba-Geigy Corp. Aminosulfonic acid derivatives and processes for their preparation
US6024964A (en) * 1985-06-24 2000-02-15 Hoechst Aktiengesellschaft Membrane anchor/active compound conjugate, its preparation and its uses
US6074650A (en) * 1985-06-24 2000-06-13 Hoechst Aktiengesellschaft Membrane anchor/active compound conjugate, its preparation and its uses

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0014815A3 (fr) * 1978-12-20 1980-10-29 Ciba-Geigy Ag Dérivés peptidiques, procédé pour leur préparation et intermédiaires, et compositions pharmaceutiques contenant un de ces composés
EP0114787B1 (fr) * 1983-01-25 1991-09-25 Ciba-Geigy Ag Dérivés peptidiques
FR2546164B1 (fr) * 1983-05-16 1987-07-17 Centre Nat Rech Scient Nouveaux derives de peptides, leur preparation et leur application comme inhibiteurs de l'elastase
DE3546150A1 (de) * 1985-06-24 1987-01-22 Hoechst Ag Membrananker-wirkstoffkonjugat, seine herstellung sowie seine verwendung
DE3522638A1 (de) * 1985-06-25 1987-01-08 Diamalt Ag Neue somatostatin-derivate
FR2611205B1 (fr) * 1987-02-20 1990-03-02 Serbio Dipeptides, procede de preparation et utilisation dans le dosage de proteases
EP0306912A3 (fr) * 1987-09-08 1989-07-05 Albany Medical College Ensemble immunogène capable de provoquer sélectivement la production d'anticorps et compositions pharmaceutiques l'utilisant.
DE4119856A1 (de) * 1991-06-17 1992-12-24 Hoechst Ag N-acyl-s-(2-hydroxyalkyl)-cysteine, deren herstellung sowie deren verwendung als zwischenprodukte zur herstellung von synthetischen immunadjuvantien und synthetischen impfstoffen
EP0604945A1 (fr) * 1992-12-28 1994-07-06 Takeda Chemical Industries, Ltd. TAN-1511, dérivés, préparation et utilisation
AU666789B2 (en) * 1992-12-28 1996-02-22 Takeda Chemical Industries Ltd. 2-amino-6,7-dihydroxy-4-thiaheptanoic acid derivatives, production and use thereof
EP0641776A3 (fr) * 1993-09-08 1997-05-02 Takeda Chemical Industries Ltd Dérivés de thioglycérol.
GB9930591D0 (en) * 1999-12-23 2000-02-16 Univ London Component for vaccine
DE10048840A1 (de) * 2000-10-02 2002-04-11 Biotechnolog Forschung Gmbh Verwendung von Lipopeptiden oder Lipoproteinen zur Behandlung von Lungeninfektionen und -tumoren
FR2816060A1 (fr) * 2000-10-27 2002-05-03 Pf Medicament Procede d'identification de nouvelles molecules se liant au recepteur lox et utilisation de ces molecules
EA014644B1 (ru) 2005-06-13 2010-12-30 Кливлэнд Биолабс Инк. Способы защиты от апоптоза с применением липопептидов
US7608589B2 (en) * 2005-07-25 2009-10-27 Therimunex Pharmaceuticals, Inc. Peptidyl diacylglycerides
DE102016005550A1 (de) 2016-05-09 2017-11-09 Emc Microcollections Gmbh Adjuvans zur lnduzierung einer zellulären lmmunantwort
EP4365125A2 (fr) * 2017-11-06 2024-05-08 Crown Equipment Corporation Système de superposition de véhicules industriels

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2706490A1 (de) 1976-02-20 1977-08-25 Ciba Geigy Ag Neue carbonsaeureester

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6024964A (en) * 1985-06-24 2000-02-15 Hoechst Aktiengesellschaft Membrane anchor/active compound conjugate, its preparation and its uses
US6074650A (en) * 1985-06-24 2000-06-13 Hoechst Aktiengesellschaft Membrane anchor/active compound conjugate, its preparation and its uses
US5342977A (en) * 1991-12-19 1994-08-30 Ciba-Geigy Corp. Aminosulfonic acid derivatives and processes for their preparation

Also Published As

Publication number Publication date
DK275178A (da) 1978-12-21
FI781933A (fi) 1978-12-21
GR71681B (fr) 1983-06-21
DE2860893D1 (en) 1981-11-05
IE46957B1 (en) 1983-11-16
ZA783504B (en) 1979-06-27
IL54950A (en) 1983-10-31
PT68188A (de) 1978-07-01
IE781227L (en) 1978-12-20
NO148921C (no) 1984-01-11
AU525005B2 (en) 1982-10-14
NO148921B (no) 1983-10-03
JPS6360760B2 (fr) 1988-11-25
ES478718A1 (es) 1979-12-16
AT364095B (de) 1981-09-25
EP0000330B1 (fr) 1981-08-05
NO782138L (no) 1978-12-21
NZ187611A (en) 1981-07-13
PL216739A1 (fr) 1980-05-19
ATA445178A (de) 1981-02-15
ES470961A1 (es) 1980-03-01
JPS549224A (en) 1979-01-24
JPS641466B2 (fr) 1989-01-11
PL216740A1 (fr) 1980-05-19
AU3723078A (en) 1980-01-03
PL207766A1 (pl) 1979-11-19
EP0000330A1 (fr) 1979-01-24
IL54950A0 (en) 1978-08-31
DD139257A5 (de) 1979-12-19
ES478717A1 (es) 1979-12-16
JPS6372671A (ja) 1988-04-02

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Legal Events

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