DE2860893D1 - Lipopeptides, process for their preparation and pharmaceutical compositions containing them - Google Patents

Lipopeptides, process for their preparation and pharmaceutical compositions containing them

Info

Publication number
DE2860893D1
DE2860893D1 DE7878100149T DE2860893T DE2860893D1 DE 2860893 D1 DE2860893 D1 DE 2860893D1 DE 7878100149 T DE7878100149 T DE 7878100149T DE 2860893 T DE2860893 T DE 2860893T DE 2860893 D1 DE2860893 D1 DE 2860893D1
Authority
DE
Germany
Prior art keywords
lipopeptides
preparation
pharmaceutical compositions
compositions containing
pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE7878100149T
Other languages
English (en)
Inventor
Lajos Zoltan Dr Tarcsay
Bruno Dr Kamber
Jaroslav Dr Stanek
Gerhard Dr Baschang
Albert Dr Hartmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Application granted granted Critical
Publication of DE2860893D1 publication Critical patent/DE2860893D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/0606—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing heteroatoms not provided for by C07K5/06086 - C07K5/06139, e.g. Ser, Met, Cys, Thr
    • C07K5/06069—Ser-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/081—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1013—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
DE7878100149T 1977-06-20 1978-06-14 Lipopeptides, process for their preparation and pharmaceutical compositions containing them Expired DE2860893D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU77584 1977-06-20

Publications (1)

Publication Number Publication Date
DE2860893D1 true DE2860893D1 (en) 1981-11-05

Family

ID=19728618

Family Applications (1)

Application Number Title Priority Date Filing Date
DE7878100149T Expired DE2860893D1 (en) 1977-06-20 1978-06-14 Lipopeptides, process for their preparation and pharmaceutical compositions containing them

Country Status (18)

Country Link
EP (1) EP0000330B1 (de)
JP (2) JPS549224A (de)
AT (1) AT364095B (de)
AU (1) AU525005B2 (de)
CA (1) CA1139305A (de)
DD (1) DD139257A5 (de)
DE (1) DE2860893D1 (de)
DK (1) DK275178A (de)
ES (3) ES470961A1 (de)
FI (1) FI781933A (de)
GR (1) GR71681B (de)
IE (1) IE46957B1 (de)
IL (1) IL54950A (de)
NO (1) NO148921C (de)
NZ (1) NZ187611A (de)
PL (3) PL207766A1 (de)
PT (1) PT68188A (de)
ZA (1) ZA783504B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0014815A3 (de) * 1978-12-20 1980-10-29 Ciba-Geigy Ag Peptidderivate, Verfahren zu deren Herstellung und Zwischenprodukte sowie pharmazeutische Präparate mit einer dieser Verbindungen
DE3485094D1 (de) * 1983-01-25 1991-10-31 Ciba Geigy Ag Neue peptidderivate.
FR2546164B1 (fr) * 1983-05-16 1987-07-17 Centre Nat Rech Scient Nouveaux derives de peptides, leur preparation et leur application comme inhibiteurs de l'elastase
US6074650A (en) * 1985-06-24 2000-06-13 Hoechst Aktiengesellschaft Membrane anchor/active compound conjugate, its preparation and its uses
DE3546150A1 (de) * 1985-06-24 1987-01-22 Hoechst Ag Membrananker-wirkstoffkonjugat, seine herstellung sowie seine verwendung
US6024964A (en) * 1985-06-24 2000-02-15 Hoechst Aktiengesellschaft Membrane anchor/active compound conjugate, its preparation and its uses
DE3522638A1 (de) * 1985-06-25 1987-01-08 Diamalt Ag Neue somatostatin-derivate
FR2611205B1 (fr) * 1987-02-20 1990-03-02 Serbio Dipeptides, procede de preparation et utilisation dans le dosage de proteases
EP0306912A3 (de) * 1987-09-08 1989-07-05 Albany Medical College Zur selektiven Anregung der Antikörperbildung befähigte immunogene Produkte und ihre Verwendung in pharmazeutischen Zusammensetzungen.
DE4119856A1 (de) * 1991-06-17 1992-12-24 Hoechst Ag N-acyl-s-(2-hydroxyalkyl)-cysteine, deren herstellung sowie deren verwendung als zwischenprodukte zur herstellung von synthetischen immunadjuvantien und synthetischen impfstoffen
ATE147404T1 (de) * 1991-12-19 1997-01-15 Ciba Geigy Ag Aminosulfonsäurederivate und verfahren zu ihrer herstellung
AU666789B2 (en) * 1992-12-28 1996-02-22 Takeda Chemical Industries Ltd. 2-amino-6,7-dihydroxy-4-thiaheptanoic acid derivatives, production and use thereof
EP0604945A1 (de) * 1992-12-28 1994-07-06 Takeda Chemical Industries, Ltd. TAN-1511, Derivate, Herstellung und Verwendung
EP0641776A3 (de) * 1993-09-08 1997-05-02 Takeda Chemical Industries Ltd Thioglycerinderivate.
GB9930591D0 (en) * 1999-12-23 2000-02-16 Univ London Component for vaccine
DE10048840A1 (de) * 2000-10-02 2002-04-11 Biotechnolog Forschung Gmbh Verwendung von Lipopeptiden oder Lipoproteinen zur Behandlung von Lungeninfektionen und -tumoren
FR2816060A1 (fr) * 2000-10-27 2002-05-03 Pf Medicament Procede d'identification de nouvelles molecules se liant au recepteur lox et utilisation de ces molecules
ES2539490T3 (es) 2005-06-13 2015-07-01 Cleveland Biolabs, Inc. Métodos para proteger frente a apoptosis usando lipopéptidos
AU2006272647A1 (en) * 2005-07-25 2007-02-01 Therimunex Pharmaceuticals, Inc. Peptidyl diacylglycerides
DE102016005550A1 (de) 2016-05-09 2017-11-09 Emc Microcollections Gmbh Adjuvans zur lnduzierung einer zellulären lmmunantwort
CA3076675A1 (en) * 2017-11-06 2019-05-09 Crown Equipment Corporation Industrial vehicle layover system

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2706490A1 (de) 1976-02-20 1977-08-25 Ciba Geigy Ag Neue carbonsaeureester

Also Published As

Publication number Publication date
IL54950A (en) 1983-10-31
JPS549224A (en) 1979-01-24
AT364095B (de) 1981-09-25
AU525005B2 (en) 1982-10-14
PL216739A1 (de) 1980-05-19
JPS6372671A (ja) 1988-04-02
NO782138L (no) 1978-12-21
ES478718A1 (es) 1979-12-16
PT68188A (de) 1978-07-01
EP0000330A1 (de) 1979-01-24
EP0000330B1 (de) 1981-08-05
ZA783504B (en) 1979-06-27
NZ187611A (en) 1981-07-13
ES478717A1 (es) 1979-12-16
PL216740A1 (de) 1980-05-19
IE781227L (en) 1978-12-20
ES470961A1 (es) 1980-03-01
GR71681B (de) 1983-06-21
JPS641466B2 (de) 1989-01-11
JPS6360760B2 (de) 1988-11-25
CA1139305A (en) 1983-01-11
IL54950A0 (en) 1978-08-31
PL207766A1 (pl) 1979-11-19
DD139257A5 (de) 1979-12-19
NO148921C (no) 1984-01-11
IE46957B1 (en) 1983-11-16
NO148921B (no) 1983-10-03
AU3723078A (en) 1980-01-03
ATA445178A (de) 1981-02-15
DK275178A (da) 1978-12-21
FI781933A (fi) 1978-12-21

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: NOVARTIS AG, BASEL, CH