IL54950A - N,o,o,triacyl-s-(2,3-dihydroxypropyl)-cysteine,n,o,o,o,-tetraacyl-s-(2,3,4-trihydroxy-butyl)-cysteine,peptide derivatives thereof,their production and pharmaceutical compositions containing them - Google Patents

N,o,o,triacyl-s-(2,3-dihydroxypropyl)-cysteine,n,o,o,o,-tetraacyl-s-(2,3,4-trihydroxy-butyl)-cysteine,peptide derivatives thereof,their production and pharmaceutical compositions containing them

Info

Publication number
IL54950A
IL54950A IL54950A IL5495078A IL54950A IL 54950 A IL54950 A IL 54950A IL 54950 A IL54950 A IL 54950A IL 5495078 A IL5495078 A IL 5495078A IL 54950 A IL54950 A IL 54950A
Authority
IL
Israel
Prior art keywords
cysteine
tetraacyl
triacyl
dihydroxypropyl
trihydroxy
Prior art date
Application number
IL54950A
Other languages
English (en)
Other versions
IL54950A0 (en
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of IL54950A0 publication Critical patent/IL54950A0/xx
Publication of IL54950A publication Critical patent/IL54950A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245Escherichia (G)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/0606Dipeptides with the first amino acid being neutral and aliphatic the side chain containing heteroatoms not provided for by C07K5/06086 - C07K5/06139, e.g. Ser, Met, Cys, Thr
    • C07K5/06069Ser-amino acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0804Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/081Tripeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0812Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1002Tetrapeptides with the first amino acid being neutral
    • C07K5/1005Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1013Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IL54950A 1977-06-20 1978-06-19 N,o,o,triacyl-s-(2,3-dihydroxypropyl)-cysteine,n,o,o,o,-tetraacyl-s-(2,3,4-trihydroxy-butyl)-cysteine,peptide derivatives thereof,their production and pharmaceutical compositions containing them IL54950A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU77584 1977-06-20

Publications (2)

Publication Number Publication Date
IL54950A0 IL54950A0 (en) 1978-08-31
IL54950A true IL54950A (en) 1983-10-31

Family

ID=19728618

Family Applications (1)

Application Number Title Priority Date Filing Date
IL54950A IL54950A (en) 1977-06-20 1978-06-19 N,o,o,triacyl-s-(2,3-dihydroxypropyl)-cysteine,n,o,o,o,-tetraacyl-s-(2,3,4-trihydroxy-butyl)-cysteine,peptide derivatives thereof,their production and pharmaceutical compositions containing them

Country Status (18)

Country Link
EP (1) EP0000330B1 (xx)
JP (2) JPS549224A (xx)
AT (1) AT364095B (xx)
AU (1) AU525005B2 (xx)
CA (1) CA1139305A (xx)
DD (1) DD139257A5 (xx)
DE (1) DE2860893D1 (xx)
DK (1) DK275178A (xx)
ES (3) ES470961A1 (xx)
FI (1) FI781933A (xx)
GR (1) GR71681B (xx)
IE (1) IE46957B1 (xx)
IL (1) IL54950A (xx)
NO (1) NO148921C (xx)
NZ (1) NZ187611A (xx)
PL (3) PL216740A1 (xx)
PT (1) PT68188A (xx)
ZA (1) ZA783504B (xx)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0014815A3 (de) * 1978-12-20 1980-10-29 Ciba-Geigy Ag Peptidderivate, Verfahren zu deren Herstellung und Zwischenprodukte sowie pharmazeutische Präparate mit einer dieser Verbindungen
DE3485094D1 (de) * 1983-01-25 1991-10-31 Ciba Geigy Ag Neue peptidderivate.
FR2546164B1 (fr) * 1983-05-16 1987-07-17 Centre Nat Rech Scient Nouveaux derives de peptides, leur preparation et leur application comme inhibiteurs de l'elastase
DE3546150A1 (de) * 1985-06-24 1987-01-22 Hoechst Ag Membrananker-wirkstoffkonjugat, seine herstellung sowie seine verwendung
US6074650A (en) * 1985-06-24 2000-06-13 Hoechst Aktiengesellschaft Membrane anchor/active compound conjugate, its preparation and its uses
US6024964A (en) * 1985-06-24 2000-02-15 Hoechst Aktiengesellschaft Membrane anchor/active compound conjugate, its preparation and its uses
DE3522638A1 (de) * 1985-06-25 1987-01-08 Diamalt Ag Neue somatostatin-derivate
FR2611205B1 (fr) * 1987-02-20 1990-03-02 Serbio Dipeptides, procede de preparation et utilisation dans le dosage de proteases
AU626797B2 (en) * 1987-09-08 1992-08-13 Albany Medical College Immunogenic composites capable of selectively inducing antibody production, pharmaceutical compositions employing the same and method of selectively inducing antibody production
DE4119856A1 (de) * 1991-06-17 1992-12-24 Hoechst Ag N-acyl-s-(2-hydroxyalkyl)-cysteine, deren herstellung sowie deren verwendung als zwischenprodukte zur herstellung von synthetischen immunadjuvantien und synthetischen impfstoffen
SG47406A1 (en) * 1991-12-19 1998-04-17 Ciba Geigy Ag Aminosulfonic acid derivatives and processes for their preparation
EP0604945A1 (en) * 1992-12-28 1994-07-06 Takeda Chemical Industries, Ltd. TAN-1511, its derivatives, production and use thereof
AU666789B2 (en) * 1992-12-28 1996-02-22 Takeda Chemical Industries Ltd. 2-amino-6,7-dihydroxy-4-thiaheptanoic acid derivatives, production and use thereof
EP0641776A3 (en) * 1993-09-08 1997-05-02 Takeda Chemical Industries Ltd Thioglycerol derivatives.
GB9930591D0 (en) * 1999-12-23 2000-02-16 Univ London Component for vaccine
DE10048840A1 (de) * 2000-10-02 2002-04-11 Biotechnolog Forschung Gmbh Verwendung von Lipopeptiden oder Lipoproteinen zur Behandlung von Lungeninfektionen und -tumoren
FR2816060A1 (fr) * 2000-10-27 2002-05-03 Pf Medicament Procede d'identification de nouvelles molecules se liant au recepteur lox et utilisation de ces molecules
NZ565063A (en) 2005-06-13 2011-04-29 Cleveland Biolabs Inc Methods of protecting against apoptosis using lipopeptides
MX2008001183A (es) * 2005-07-25 2008-04-11 Therimunex Llc Peptidil diacilgliceridos.
DE102016005550B4 (de) 2016-05-09 2024-09-26 Hans-Georg Rammensee Adjuvans zur lnduzierung einer zellulären lmmunantwort
EP4365125A3 (en) * 2017-11-06 2024-08-21 Crown Equipment Corporation Industrial vehicle layover system

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2706490A1 (de) 1976-02-20 1977-08-25 Ciba Geigy Ag Neue carbonsaeureester

Also Published As

Publication number Publication date
ES478718A1 (es) 1979-12-16
DK275178A (da) 1978-12-21
AT364095B (de) 1981-09-25
DD139257A5 (de) 1979-12-19
NO148921B (no) 1983-10-03
AU525005B2 (en) 1982-10-14
PL207766A1 (pl) 1979-11-19
NO148921C (no) 1984-01-11
JPS641466B2 (xx) 1989-01-11
EP0000330A1 (de) 1979-01-24
ZA783504B (en) 1979-06-27
FI781933A (fi) 1978-12-21
EP0000330B1 (de) 1981-08-05
ES478717A1 (es) 1979-12-16
NO782138L (no) 1978-12-21
CA1139305A (en) 1983-01-11
NZ187611A (en) 1981-07-13
ATA445178A (de) 1981-02-15
GR71681B (xx) 1983-06-21
JPS549224A (en) 1979-01-24
IE46957B1 (en) 1983-11-16
DE2860893D1 (en) 1981-11-05
IL54950A0 (en) 1978-08-31
ES470961A1 (es) 1980-03-01
PT68188A (de) 1978-07-01
JPS6360760B2 (xx) 1988-11-25
PL216739A1 (xx) 1980-05-19
JPS6372671A (ja) 1988-04-02
PL216740A1 (xx) 1980-05-19
IE781227L (en) 1978-12-20
AU3723078A (en) 1980-01-03

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