IL54950A - N,o,o,triacyl-s-(2,3-dihydroxypropyl)-cysteine,n,o,o,o,-tetraacyl-s-(2,3,4-trihydroxy-butyl)-cysteine,peptide derivatives thereof,their production and pharmaceutical compositions containing them - Google Patents

N,o,o,triacyl-s-(2,3-dihydroxypropyl)-cysteine,n,o,o,o,-tetraacyl-s-(2,3,4-trihydroxy-butyl)-cysteine,peptide derivatives thereof,their production and pharmaceutical compositions containing them

Info

Publication number
IL54950A
IL54950A IL54950A IL5495078A IL54950A IL 54950 A IL54950 A IL 54950A IL 54950 A IL54950 A IL 54950A IL 5495078 A IL5495078 A IL 5495078A IL 54950 A IL54950 A IL 54950A
Authority
IL
Israel
Prior art keywords
cysteine
tetraacyl
triacyl
dihydroxypropyl
trihydroxy
Prior art date
Application number
IL54950A
Other languages
English (en)
Other versions
IL54950A0 (en
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of IL54950A0 publication Critical patent/IL54950A0/xx
Publication of IL54950A publication Critical patent/IL54950A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/0606—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing heteroatoms not provided for by C07K5/06086 - C07K5/06139, e.g. Ser, Met, Cys, Thr
    • C07K5/06069—Ser-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/081—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1013—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IL54950A 1977-06-20 1978-06-19 N,o,o,triacyl-s-(2,3-dihydroxypropyl)-cysteine,n,o,o,o,-tetraacyl-s-(2,3,4-trihydroxy-butyl)-cysteine,peptide derivatives thereof,their production and pharmaceutical compositions containing them IL54950A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU77584 1977-06-20

Publications (2)

Publication Number Publication Date
IL54950A0 IL54950A0 (en) 1978-08-31
IL54950A true IL54950A (en) 1983-10-31

Family

ID=19728618

Family Applications (1)

Application Number Title Priority Date Filing Date
IL54950A IL54950A (en) 1977-06-20 1978-06-19 N,o,o,triacyl-s-(2,3-dihydroxypropyl)-cysteine,n,o,o,o,-tetraacyl-s-(2,3,4-trihydroxy-butyl)-cysteine,peptide derivatives thereof,their production and pharmaceutical compositions containing them

Country Status (18)

Country Link
EP (1) EP0000330B1 (fr)
JP (2) JPS549224A (fr)
AT (1) AT364095B (fr)
AU (1) AU525005B2 (fr)
CA (1) CA1139305A (fr)
DD (1) DD139257A5 (fr)
DE (1) DE2860893D1 (fr)
DK (1) DK275178A (fr)
ES (3) ES470961A1 (fr)
FI (1) FI781933A (fr)
GR (1) GR71681B (fr)
IE (1) IE46957B1 (fr)
IL (1) IL54950A (fr)
NO (1) NO148921C (fr)
NZ (1) NZ187611A (fr)
PL (3) PL216740A1 (fr)
PT (1) PT68188A (fr)
ZA (1) ZA783504B (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0014815A3 (fr) * 1978-12-20 1980-10-29 Ciba-Geigy Ag Dérivés peptidiques, procédé pour leur préparation et intermédiaires, et compositions pharmaceutiques contenant un de ces composés
EP0114787B1 (fr) * 1983-01-25 1991-09-25 Ciba-Geigy Ag Dérivés peptidiques
FR2546164B1 (fr) * 1983-05-16 1987-07-17 Centre Nat Rech Scient Nouveaux derives de peptides, leur preparation et leur application comme inhibiteurs de l'elastase
DE3546150A1 (de) * 1985-06-24 1987-01-22 Hoechst Ag Membrananker-wirkstoffkonjugat, seine herstellung sowie seine verwendung
US6024964A (en) * 1985-06-24 2000-02-15 Hoechst Aktiengesellschaft Membrane anchor/active compound conjugate, its preparation and its uses
US6074650A (en) * 1985-06-24 2000-06-13 Hoechst Aktiengesellschaft Membrane anchor/active compound conjugate, its preparation and its uses
DE3522638A1 (de) * 1985-06-25 1987-01-08 Diamalt Ag Neue somatostatin-derivate
FR2611205B1 (fr) * 1987-02-20 1990-03-02 Serbio Dipeptides, procede de preparation et utilisation dans le dosage de proteases
AU626797B2 (en) * 1987-09-08 1992-08-13 Albany Medical College Immunogenic composites capable of selectively inducing antibody production, pharmaceutical compositions employing the same and method of selectively inducing antibody production
DE4119856A1 (de) * 1991-06-17 1992-12-24 Hoechst Ag N-acyl-s-(2-hydroxyalkyl)-cysteine, deren herstellung sowie deren verwendung als zwischenprodukte zur herstellung von synthetischen immunadjuvantien und synthetischen impfstoffen
ATE147404T1 (de) * 1991-12-19 1997-01-15 Ciba Geigy Ag Aminosulfonsäurederivate und verfahren zu ihrer herstellung
AU666789B2 (en) * 1992-12-28 1996-02-22 Takeda Chemical Industries Ltd. 2-amino-6,7-dihydroxy-4-thiaheptanoic acid derivatives, production and use thereof
EP0604945A1 (fr) 1992-12-28 1994-07-06 Takeda Chemical Industries, Ltd. TAN-1511, dérivés, préparation et utilisation
EP0641776A3 (fr) * 1993-09-08 1997-05-02 Takeda Chemical Industries Ltd Dérivés de thioglycérol.
GB9930591D0 (en) * 1999-12-23 2000-02-16 Univ London Component for vaccine
DE10048840A1 (de) * 2000-10-02 2002-04-11 Biotechnolog Forschung Gmbh Verwendung von Lipopeptiden oder Lipoproteinen zur Behandlung von Lungeninfektionen und -tumoren
FR2816060A1 (fr) * 2000-10-27 2002-05-03 Pf Medicament Procede d'identification de nouvelles molecules se liant au recepteur lox et utilisation de ces molecules
CN101242852B (zh) 2005-06-13 2012-10-10 克里夫兰生物实验室公司 利用脂肽抵抗细胞凋亡的保护方法
JP2009506986A (ja) * 2005-07-25 2009-02-19 サーミュネックス、エルエルシー ペプチジルジアシルグリセリド
DE102016005550A1 (de) 2016-05-09 2017-11-09 Emc Microcollections Gmbh Adjuvans zur lnduzierung einer zellulären lmmunantwort
KR20200078552A (ko) * 2017-11-06 2020-07-01 크라운 이큅먼트 코포레이션 산업용 차량 레이오버 시스템

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2706490A1 (de) 1976-02-20 1977-08-25 Ciba Geigy Ag Neue carbonsaeureester

Also Published As

Publication number Publication date
FI781933A (fi) 1978-12-21
DD139257A5 (de) 1979-12-19
CA1139305A (fr) 1983-01-11
ZA783504B (en) 1979-06-27
IL54950A0 (en) 1978-08-31
AU3723078A (en) 1980-01-03
AU525005B2 (en) 1982-10-14
IE46957B1 (en) 1983-11-16
IE781227L (en) 1978-12-20
NO148921B (no) 1983-10-03
EP0000330B1 (fr) 1981-08-05
NO782138L (no) 1978-12-21
NO148921C (no) 1984-01-11
PL207766A1 (pl) 1979-11-19
JPS6372671A (ja) 1988-04-02
AT364095B (de) 1981-09-25
ATA445178A (de) 1981-02-15
JPS6360760B2 (fr) 1988-11-25
ES470961A1 (es) 1980-03-01
JPS641466B2 (fr) 1989-01-11
ES478717A1 (es) 1979-12-16
JPS549224A (en) 1979-01-24
DE2860893D1 (en) 1981-11-05
EP0000330A1 (fr) 1979-01-24
NZ187611A (en) 1981-07-13
ES478718A1 (es) 1979-12-16
PL216740A1 (fr) 1980-05-19
DK275178A (da) 1978-12-21
PT68188A (de) 1978-07-01
PL216739A1 (fr) 1980-05-19
GR71681B (fr) 1983-06-21

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