CA1102332A - Intermediate product for the production of 6,7- dimethoxy-4-amino-2-¬4-(2-furoyl)-1- piperazinyl|quinazoline having an antihypertensive effect - Google Patents

Intermediate product for the production of 6,7- dimethoxy-4-amino-2-¬4-(2-furoyl)-1- piperazinyl|quinazoline having an antihypertensive effect

Info

Publication number
CA1102332A
CA1102332A CA293,066A CA293066A CA1102332A CA 1102332 A CA1102332 A CA 1102332A CA 293066 A CA293066 A CA 293066A CA 1102332 A CA1102332 A CA 1102332A
Authority
CA
Canada
Prior art keywords
furoyl
dimethoxy
formula
benzonitrile
reacting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA293,066A
Other languages
English (en)
French (fr)
Inventor
Erkki J. Honkanen
Aino K. Pippuri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Orion Oyj
Original Assignee
Orion Yhtyma Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Yhtyma Oy filed Critical Orion Yhtyma Oy
Application granted granted Critical
Publication of CA1102332A publication Critical patent/CA1102332A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA293,066A 1976-12-15 1977-12-14 Intermediate product for the production of 6,7- dimethoxy-4-amino-2-¬4-(2-furoyl)-1- piperazinyl|quinazoline having an antihypertensive effect Expired CA1102332A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI763614A FI58124C (fi) 1976-12-15 1976-12-15 Ny mellanprodukt 3,4-dimetoxi-6-(4-(2-furoyl)-1-piperazinyltiokarbamido)-bensonitril foer framstaellning av 6,7-dimetoxi-4-amino-2-(4-(2-furoyl)-1-piperazinyl)kinazolin med blodtryckssaenkande verkan
FI763614 1976-12-15

Publications (1)

Publication Number Publication Date
CA1102332A true CA1102332A (en) 1981-06-02

Family

ID=8510504

Family Applications (1)

Application Number Title Priority Date Filing Date
CA293,066A Expired CA1102332A (en) 1976-12-15 1977-12-14 Intermediate product for the production of 6,7- dimethoxy-4-amino-2-¬4-(2-furoyl)-1- piperazinyl|quinazoline having an antihypertensive effect

Country Status (17)

Country Link
JP (1) JPS5387375A (xx)
AT (1) AT358047B (xx)
BE (1) BE861822A (xx)
CA (1) CA1102332A (xx)
CH (1) CH630624A5 (xx)
CS (1) CS197312B2 (xx)
DD (1) DD134226A1 (xx)
DE (1) DE2755638A1 (xx)
DK (1) DK145822C (xx)
FI (1) FI58124C (xx)
HU (1) HU174048B (xx)
NL (1) NL7713703A (xx)
NO (1) NO146239C (xx)
PL (1) PL106201B1 (xx)
SE (1) SE424993B (xx)
SU (1) SU923370A3 (xx)
ZA (1) ZA777222B (xx)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI67699C (fi) * 1979-01-31 1985-05-10 Orion Yhtymae Oy Foerfarande foer framstaellning av 6,7-dimetoxi-4-amino-2-(4-(2-furoyl)-1-piperazinyl)kinazolinhydroklorid med blodtryckssaenkande verkan

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3935213A (en) * 1973-12-05 1976-01-27 Pfizer Inc. Process for hypotensive 4-amino-2-(piperazin-1-yl) quinazoline derivatives

Also Published As

Publication number Publication date
BE861822A (fr) 1978-03-31
NO774263L (no) 1978-06-16
NO146239B (no) 1982-05-18
FI58124C (fi) 1980-12-10
AT358047B (de) 1980-08-11
DD134226A1 (de) 1979-02-14
ZA777222B (en) 1978-09-27
ATA867177A (de) 1980-01-15
DK558377A (da) 1978-06-16
CS197312B2 (en) 1980-04-30
DE2755638A1 (de) 1978-06-22
SE7713377L (sv) 1978-06-16
PL202898A1 (pl) 1978-08-28
NO146239C (no) 1982-08-25
CH630624A5 (en) 1982-06-30
DK145822C (da) 1983-08-29
PL106201B1 (pl) 1979-12-31
FI763614A (fi) 1978-06-16
JPS6225145B2 (xx) 1987-06-01
SE424993B (sv) 1982-08-23
DK145822B (da) 1983-03-14
SU923370A3 (ru) 1982-04-23
HU174048B (hu) 1979-10-28
FI58124B (fi) 1980-08-29
NL7713703A (nl) 1978-06-19
JPS5387375A (en) 1978-08-01

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