CA1073911A - Antimicrobial bis-pyridinium compounds - Google Patents

Antimicrobial bis-pyridinium compounds

Info

Publication number
CA1073911A
CA1073911A CA272,596A CA272596A CA1073911A CA 1073911 A CA1073911 A CA 1073911A CA 272596 A CA272596 A CA 272596A CA 1073911 A CA1073911 A CA 1073911A
Authority
CA
Canada
Prior art keywords
bis
formula
pyridinium
mole
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA272,596A
Other languages
English (en)
French (fr)
Inventor
Denis M. Bailey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
STWB Inc
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/734,729 external-priority patent/US4107313A/en
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Application granted granted Critical
Publication of CA1073911A publication Critical patent/CA1073911A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/73Unsubstituted amino or imino radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/74Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/75Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
CA272,596A 1976-02-25 1977-02-24 Antimicrobial bis-pyridinium compounds Expired CA1073911A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US66112876A 1976-02-25 1976-02-25
US66110176A 1976-02-25 1976-02-25
US72131576A 1976-09-07 1976-09-07
US05/734,729 US4107313A (en) 1976-02-25 1976-10-22 α,α-Bis-[4-(R-amino)-1-pyridinium]xylenes and antibacterial and antifungal uses

Publications (1)

Publication Number Publication Date
CA1073911A true CA1073911A (en) 1980-03-18

Family

ID=27505307

Family Applications (1)

Application Number Title Priority Date Filing Date
CA272,596A Expired CA1073911A (en) 1976-02-25 1977-02-24 Antimicrobial bis-pyridinium compounds

Country Status (23)

Country Link
JP (1) JPS6033108B2 (ja)
AR (2) AR214876A1 (ja)
AT (1) AT355571B (ja)
AU (1) AU510149B2 (ja)
BE (1) BE851807A (ja)
CA (1) CA1073911A (ja)
CH (1) CH620907A5 (ja)
DE (1) DE2708331A1 (ja)
DK (1) DK147638C (ja)
ES (1) ES456252A1 (ja)
FI (1) FI66850C (ja)
FR (1) FR2342286A1 (ja)
GB (1) GB1533952A (ja)
HK (1) HK67484A (ja)
IE (1) IE45336B1 (ja)
IL (1) IL51520A (ja)
LU (1) LU76837A1 (ja)
MX (1) MX5132E (ja)
NL (1) NL186086C (ja)
NO (2) NO148779C (ja)
PH (2) PH22315A (ja)
PT (1) PT66224B (ja)
SE (1) SE432421B (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9770019B2 (en) 2013-11-20 2017-09-26 L'air Liquide, Societe Anonyme Pour L'etude Et L'exploitation Des Procedes Georges Claude Kit for producing foams containing bispyridinium alkane

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE32300E (en) * 1979-08-13 1986-12-02 Sterling Drug Inc. Basic amino or ammonium antimicrobial agent-polyethylene glycol ester surfactant-betaine and/or amine oxide surfactant compositions and method of use thereof
US4420484A (en) 1979-08-13 1983-12-13 Sterling Drug Inc. Basic amino or ammonium antimicrobial agent-polyethylene glycol ester surfactant-betaine and/or amine oxide surfactant compositions and method of use therof
DE19647413A1 (de) * 1996-11-15 1998-05-20 Hoechst Schering Agrevo Gmbh Substituierte Stickstoff-Heterocyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Schädlingsbekämpfungsmittel
DE19647317A1 (de) * 1996-11-15 1998-05-20 Hoechst Schering Agrevo Gmbh Substituierte Stickstoff-Heterocyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Schädlingsbekämpfungsmittel
DE19647402A1 (de) * 1996-11-15 1998-05-20 Hoechst Schering Agrevo Gmbh Substituierte Stickstoff-Heterocyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Schädlingsbekämpfungsmittel
DE10005853C1 (de) 2000-02-10 2002-02-07 Schuelke & Mayr Gmbh Verfahren zur Herstellung von Bis-(4-amino-1-pyridinium)-alkanen
DE10205883A1 (de) * 2002-02-13 2003-08-21 Schuelke & Mayr Gmbh Wässriges Antiseptikum auf Basis von Bispyridiniumalkanen
TWI278315B (en) * 2003-06-13 2007-04-11 Ind Tech Res Inst A compound having anti-virus activity
ES2237332B1 (es) * 2004-01-14 2006-11-01 Consejo Sup. Investig. Cientificas Derivados de piridinio y quinolinio.
DE102005002644A1 (de) * 2005-01-19 2006-07-20 Schülke & Mayr GmbH Zusammensetzungen für die hygienische Händedesinfektion und die desinfizierende Händewaschung
DE102005002643B4 (de) * 2005-01-19 2007-11-22 Schülke & Mayr GmbH Zusammensetzungen für die hygienische Händedesinfektion und die desinfizierende Händewaschung
DE102005002645A1 (de) * 2005-01-19 2006-07-20 Schülke & Mayr GmbH Alkoholische Zusammensetzungen für die Desinfektion
DE102005063375A1 (de) * 2005-09-15 2007-04-19 Schülke & Mayr GmbH Antimikrobielle Zubereitungen mit einem Gehalt an Octenidindihydrochlorid verkapselt in Liposomen
DE102005045145A1 (de) * 2005-09-15 2007-03-29 Schülke & Mayr GmbH Verwendung von Octenidindihydrochlorid in halbfesten Zubereitungen
DE102005048131A1 (de) * 2005-10-06 2007-04-12 Bayer Innovation Gmbh Antimikrobielle Kunststoffzusammensetzung mit niedriger Elutionsrate und langer Wirksamkeit
DE102005048132A1 (de) * 2005-10-06 2007-04-12 Bayer Innovation Gmbh Verfahren zur Herstellung antimikrobieller Kunststoffzusammensetzungen
DE102006012991A1 (de) 2006-03-22 2007-10-11 Bayer Innovation Gmbh Verfahren und Vorrichtung zum optischen Auslesen von Informationen
DE102006051891A1 (de) 2006-10-31 2008-05-08 Schülke & Mayr GmbH Antimikrobiell wirksame Zusammensetzung mit einem Gehalt an Bispyridiniumalkan
DE102008011691A1 (de) 2008-02-28 2009-09-10 Schülke & Mayr GmbH Stabilisierte, antimikrobiell wirksame Zusammensetzung mit einem Gehalt an Bispyridiniumalkan
DE102009049504A1 (de) 2009-10-15 2011-04-21 Schülke & Mayr GmbH Wund- und Schleimhautantiseptikum auf der Basis von Bispyridiniumalkanen
DE102010022367A1 (de) 2010-04-20 2011-10-20 Klosterfrau Berlin Gmbh Gel, insbesondere Gleitgel, und seine Verwendung
EP2384733B1 (de) * 2010-05-07 2016-07-27 Ivoclar Vivadent AG Antimikrobielle Dentalwerkstoffe
DE102010025932A1 (de) 2010-07-02 2012-01-05 Schülke & Mayr GmbH Antiseptikum auf der Basis von Bispyridiniumalkanen
DE102011077432A1 (de) * 2011-06-10 2012-12-13 Schülke & Mayr GmbH Verwendung von Bispyridiniumalkanen zur Abtötung von Sporen
DE102012215511A1 (de) 2012-08-31 2014-06-12 Schülke & Mayr GmbH Verfahren zur Herstellung einer Bispyridiniumalkan enthaltenden halbfesten Zubereitung
DE102014107413A1 (de) 2014-05-26 2015-11-26 Schülke & Mayr GmbH Kit für das Einfärben von desinfizierten Bereichen einer Oberfläche
DE102014107412A1 (de) 2014-05-26 2015-12-17 Schülke & Mayr GmbH Gefärbte desinfizierende Zubereitung auf Basis von Bispyridiniumalkan
DE102014115080A1 (de) 2014-10-16 2016-04-21 Schülke & Mayr GmbH Verwendung von Fettsäureester zur Verbesserung der antimikrobiellen Wirksamkeit eines alkoholischen Desinfektionsmittels
CN111051285A (zh) * 2017-08-21 2020-04-21 迪氏曼卡博金艾美斯有限公司 基于奥替尼啶的化合物
EP3771338A1 (en) 2019-07-29 2021-02-03 The Procter & Gamble Company Acidic antimicrobial composition
EP3771770A1 (en) 2019-07-29 2021-02-03 The Procter & Gamble Company Antimicrobial freshening compositions
EP3771741A1 (en) 2019-07-29 2021-02-03 The Procter & Gamble Company Fabric treatment
EP3771337A1 (en) 2019-07-29 2021-02-03 The Procter & Gamble Company Antimicrobial composition
EP3771339A1 (en) 2019-07-29 2021-02-03 The Procter & Gamble Company Disinfectant composition
EP3816272B1 (en) 2019-10-31 2023-11-01 The Procter & Gamble Company Fabric care composition
CN114989076A (zh) * 2022-06-07 2022-09-02 八叶草健康产业研究院(厦门)有限公司 一种奥替尼啶碱的制备方法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9770019B2 (en) 2013-11-20 2017-09-26 L'air Liquide, Societe Anonyme Pour L'etude Et L'exploitation Des Procedes Georges Claude Kit for producing foams containing bispyridinium alkane

Also Published As

Publication number Publication date
ATA129777A (de) 1979-08-15
NL7701965A (nl) 1977-08-29
DK81277A (da) 1977-08-26
PH25097A (en) 1991-02-19
AU2258277A (en) 1978-08-31
GB1533952A (en) 1978-11-29
CH620907A5 (en) 1980-12-31
NL186086C (nl) 1990-09-17
JPS6033108B2 (ja) 1985-08-01
JPS52105228A (en) 1977-09-03
HK67484A (en) 1984-09-07
PH22315A (en) 1988-07-29
ES456252A1 (es) 1978-02-01
NO148779C (no) 1983-12-14
PT66224A (en) 1977-03-01
DE2708331A1 (de) 1977-09-08
AR214876A1 (es) 1979-08-15
IE45336B1 (en) 1982-08-11
DE2708331C2 (ja) 1991-03-21
NO150758B (no) 1984-09-03
IL51520A0 (en) 1977-04-29
AR218052A1 (es) 1980-05-15
NL186086B (nl) 1990-04-17
AU510149B2 (en) 1980-06-12
FR2342286A1 (fr) 1977-09-23
FI66850B (fi) 1984-08-31
NO148779B (no) 1983-09-05
AT355571B (de) 1980-03-10
SE7702072L (sv) 1977-10-10
FI770593A (ja) 1977-08-26
DK147638B (da) 1984-10-29
PT66224B (en) 1978-07-14
IL51520A (en) 1980-12-31
NO150758C (no) 1984-12-12
FI66850C (fi) 1984-12-10
LU76837A1 (ja) 1977-09-12
FR2342286B1 (ja) 1979-03-09
NO823274L (no) 1977-08-26
MX5132E (es) 1983-03-28
BE851807A (fr) 1977-08-25
IE45336L (en) 1977-08-25
DK147638C (da) 1985-07-15
NO770631L (no) 1977-08-26
SE432421B (sv) 1984-04-02

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