CA1068271A - N-aryl-n-(1-l-4-piperidinyl)-arylacetamides - Google Patents

N-aryl-n-(1-l-4-piperidinyl)-arylacetamides

Info

Publication number
CA1068271A
CA1068271A CA261,551A CA261551A CA1068271A CA 1068271 A CA1068271 A CA 1068271A CA 261551 A CA261551 A CA 261551A CA 1068271 A CA1068271 A CA 1068271A
Authority
CA
Canada
Prior art keywords
parts
group
piperidinyl
formula
appropriate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA261,551A
Other languages
English (en)
French (fr)
Inventor
Stefan Sanczuk
Hubert K. Fr. Hermans
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Original Assignee
Janssen Pharmaceutica NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica NV filed Critical Janssen Pharmaceutica NV
Application granted granted Critical
Publication of CA1068271A publication Critical patent/CA1068271A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • C07D211/66—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having a hetero atom as the second substituent in position 4
CA261,551A 1975-09-23 1976-09-20 N-aryl-n-(1-l-4-piperidinyl)-arylacetamides Expired CA1068271A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61513175A 1975-09-23 1975-09-23
US71375676A 1976-08-12 1976-08-12

Publications (1)

Publication Number Publication Date
CA1068271A true CA1068271A (en) 1979-12-18

Family

ID=27087421

Family Applications (1)

Application Number Title Priority Date Filing Date
CA261,551A Expired CA1068271A (en) 1975-09-23 1976-09-20 N-aryl-n-(1-l-4-piperidinyl)-arylacetamides

Country Status (29)

Country Link
JP (1) JPS6016417B2 (xx)
AT (1) AT363935B (xx)
AU (1) AU510029B2 (xx)
BG (1) BG27543A3 (xx)
CA (1) CA1068271A (xx)
CH (1) CH628623A5 (xx)
CS (1) CS222663B2 (xx)
DE (1) DE2642856A1 (xx)
DK (1) DK150478C (xx)
ES (1) ES451768A1 (xx)
FI (1) FI61482C (xx)
FR (1) FR2325377A1 (xx)
GB (1) GB1539473A (xx)
GR (1) GR58469B (xx)
HU (1) HU172964B (xx)
IE (1) IE43802B1 (xx)
IL (1) IL50522A (xx)
IT (1) IT1073893B (xx)
LU (1) LU75837A1 (xx)
NL (1) NL187267C (xx)
NO (1) NO147672C (xx)
NZ (1) NZ181972A (xx)
PH (1) PH12497A (xx)
PL (2) PL192578A1 (xx)
PT (1) PT65631B (xx)
RO (1) RO70079A (xx)
SE (1) SE427839B (xx)
SU (1) SU747424A3 (xx)
YU (1) YU39973B (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA765684B (en) * 1975-09-23 1978-04-26 Janssen Pharmaceutica Nv Novel n-aryl-n-(1-l-4-piperidinyl)-arylacetamides
JPS62260786A (ja) * 1986-05-08 1987-11-13 株式会社ヘキトク 燻瓦の製造ラインにおける焼成工程後の表面仕上げ装置
JO2769B1 (en) 2005-10-26 2014-03-15 جانسين فارماسوتيكا ان. في Rapid decomposition of physiologically antagonistic agents of the 2-dopamine receptor
JO2642B1 (en) 2006-12-08 2012-06-17 جانسين فارماسوتيكا ان. في Dopamine 2 receptor antagonists are rapidly hydrolyzed
JO2849B1 (en) 2007-02-13 2015-03-15 جانسين فارماسوتيكا ان. في Dopamine 2 receptor antagonists are rapidly hydrolyzed
JP2010525013A (ja) * 2007-04-23 2010-07-22 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 高速解離性ドパミン２受容体アンタゴニストとしてのピリジン誘導体
JP5431305B2 (ja) 2007-04-23 2014-03-05 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 高速解離性ドパミン２受容体アンタゴニストとしての４−アルコキシピリダジン誘導体
AU2008240729B2 (en) 2007-04-23 2012-08-23 Janssen Pharmaceutica N.V. Thia(dia)zoles as fast dissociating dopamine 2 receptor antagonists
CA2729313C (en) 2008-07-03 2016-08-30 Janssen Pharmaceutica Nv Substituted 6-(1-piperazinyl)-pyridazines as 5-ht6 receptor antagonists
DK2307374T3 (en) 2008-07-31 2017-05-01 Janssen Pharmaceutica Nv PIPERAZIN-1-YLTRIFLUORMETHYL-SUBSTITUTED PYRIDINES AS QUICK DISSOCATING DOPAMIN-2 RECEPTOR ANTAGONISTS

Also Published As

Publication number Publication date
BG27543A3 (en) 1979-11-12
LU75837A1 (xx) 1977-05-04
NO147672C (no) 1983-05-25
YU233676A (en) 1983-01-21
NO763054L (no) 1977-03-24
FI61482C (fi) 1982-08-10
DE2642856C2 (xx) 1990-06-21
DK427876A (da) 1977-03-24
AU510029B2 (en) 1980-06-05
SE427839B (sv) 1983-05-09
SU747424A3 (ru) 1980-07-23
AU1787876A (en) 1978-03-23
YU39973B (en) 1985-06-30
FR2325377A1 (fr) 1977-04-22
DK150478B (da) 1987-03-09
NO147672B (no) 1983-02-14
JPS5239683A (en) 1977-03-28
RO70079A (ro) 1982-10-26
PT65631A (en) 1976-10-01
DE2642856A1 (de) 1977-03-24
IE43802B1 (en) 1981-06-03
PT65631B (en) 1978-07-05
SE7610501L (sv) 1977-03-24
NL7610513A (nl) 1977-03-25
AT363935B (de) 1981-09-10
NL187267B (nl) 1991-03-01
GB1539473A (en) 1979-01-31
DK150478C (da) 1987-10-05
CH628623A5 (en) 1982-03-15
ATA702976A (de) 1981-02-15
IE43802L (en) 1977-03-23
CS222663B2 (en) 1983-07-29
JPS6016417B2 (ja) 1985-04-25
PL192578A1 (pl) 1979-02-26
IT1073893B (it) 1985-04-17
FI762698A (xx) 1977-03-24
IL50522A (en) 1979-09-30
IL50522A0 (en) 1976-11-30
GR58469B (en) 1977-10-14
PH12497A (en) 1979-04-05
PL117323B1 (en) 1981-07-31
ES451768A1 (es) 1978-05-01
NL187267C (nl) 1991-08-01
NZ181972A (en) 1978-07-28
FR2325377B1 (xx) 1980-04-18
HU172964B (hu) 1979-01-28
FI61482B (fi) 1982-04-30

Similar Documents

Publication Publication Date Title
CA1080232A (en) N-(4-piperidinyl)-n-phenylamides and carbamates
US4126689A (en) N-aryl-n-(1-alkyl-4-piperidinyl)-arylacetamides
CA2033497C (en) 3-aminopiperidine derivatives and related nitrogen containing heterocycles
CA2029275A1 (en) Aromatic amine compounds, their method of preparation and pharmaceutical compositions in which they are present
CA1068271A (en) N-aryl-n-(1-l-4-piperidinyl)-arylacetamides
US4179569A (en) N-(4-piperidinyl)-N-phenylamides
CA2067834A1 (en) Dialkylenepiperidino compounds and their enantiomers, process for preparing them and pharmaceutical compositions containing them
US5039803A (en) Process for preparing aryl-substituted piperidines
CA1246564A (en) 1-(AMINOALKYL) -.alpha., .alpha.-DIARYL PYRROLIDINE-, PIPERIDINE- AND HOMOPIPERIDINE- ACETAMIDES AND ACETONITRILES
JPS5916875A (ja) 新規アリ−ルピペリジン誘導体の製造方法
US4369184A (en) 1-(Cyclohexyl)-4-aryl-4-piperidinecarboxylic acid derivatives
US5332817A (en) 3-aminopiperidine derivatives and related nitrogen containing heterocycles
US2727895A (en) Alpha-alkylated, 4-benzyl pyridines and certain substitution derivatives
DE60309251T2 (de) Verfahren zur Herstellung von Donepezil
US3850935A (en) Process for producing piperidine derivatives by degrading quaternary piperidinium salts
US4197304A (en) N-Aryl-N-(1-L-4-piperidinyl)-arylacetamides
CA2072520A1 (en) 2-(1-piperidyl) ethanol derivatives, their preparation and their therapeutic application
US4151286A (en) N-aryl-N-(1-L-4-piperidinyl)-arylacetamides
US3158609A (en) Diphenylmethyl-1-aminopiperidine hydrazones and congeners
US4686309A (en) 3-phenyl-2-propeneamine derivatives, their preparation and compositions containing them
CA1105464A (en) (4,5-dihydro-5-oxo-1h-tetrazol-1-yl)ethyl-4-¬(1-oxo- propyl)phenylamino|-4-piperidine carboxylate compounds
EP0360275A2 (en) Imidazole antiarrhythmics
US4197303A (en) N-Aryl-N-(1-L-4-piperidinyl)-arylacetamides
US4198411A (en) N-aryl-N-(1-L-4-piperidinyl)-arylaceytamides
US4208418A (en) N-Aryl-N-(1-alkyl-4-piperidinyl)arylacetamides