CA1068271A - Les n-aryl-n-(1-l-4-piperidinyl)-arylacetamides - Google Patents

Les n-aryl-n-(1-l-4-piperidinyl)-arylacetamides

Info

Publication number
CA1068271A
CA1068271A CA261,551A CA261551A CA1068271A CA 1068271 A CA1068271 A CA 1068271A CA 261551 A CA261551 A CA 261551A CA 1068271 A CA1068271 A CA 1068271A
Authority
CA
Canada
Prior art keywords
parts
group
piperidinyl
formula
appropriate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA261,551A
Other languages
English (en)
Inventor
Stefan Sanczuk
Hubert K. Fr. Hermans
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Original Assignee
Janssen Pharmaceutica NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica NV filed Critical Janssen Pharmaceutica NV
Application granted granted Critical
Publication of CA1068271A publication Critical patent/CA1068271A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • C07D211/66—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having a hetero atom as the second substituent in position 4

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA261,551A 1975-09-23 1976-09-20 Les n-aryl-n-(1-l-4-piperidinyl)-arylacetamides Expired CA1068271A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61513175A 1975-09-23 1975-09-23
US71375676A 1976-08-12 1976-08-12

Publications (1)

Publication Number Publication Date
CA1068271A true CA1068271A (fr) 1979-12-18

Family

ID=27087421

Family Applications (1)

Application Number Title Priority Date Filing Date
CA261,551A Expired CA1068271A (fr) 1975-09-23 1976-09-20 Les n-aryl-n-(1-l-4-piperidinyl)-arylacetamides

Country Status (29)

Country Link
JP (1) JPS6016417B2 (fr)
AT (1) AT363935B (fr)
AU (1) AU510029B2 (fr)
BG (1) BG27543A3 (fr)
CA (1) CA1068271A (fr)
CH (1) CH628623A5 (fr)
CS (1) CS222663B2 (fr)
DE (1) DE2642856A1 (fr)
DK (1) DK150478C (fr)
ES (1) ES451768A1 (fr)
FI (1) FI61482C (fr)
FR (1) FR2325377A1 (fr)
GB (1) GB1539473A (fr)
GR (1) GR58469B (fr)
HU (1) HU172964B (fr)
IE (1) IE43802B1 (fr)
IL (1) IL50522A (fr)
IT (1) IT1073893B (fr)
LU (1) LU75837A1 (fr)
NL (1) NL187267C (fr)
NO (1) NO147672C (fr)
NZ (1) NZ181972A (fr)
PH (1) PH12497A (fr)
PL (2) PL192578A1 (fr)
PT (1) PT65631B (fr)
RO (1) RO70079A (fr)
SE (1) SE427839B (fr)
SU (1) SU747424A3 (fr)
YU (1) YU39973B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA765684B (en) * 1975-09-23 1978-04-26 Janssen Pharmaceutica Nv Novel n-aryl-n-(1-l-4-piperidinyl)-arylacetamides
JPS62260786A (ja) * 1986-05-08 1987-11-13 株式会社ヘキトク 燻瓦の製造ラインにおける焼成工程後の表面仕上げ装置
JO2769B1 (en) 2005-10-26 2014-03-15 جانسين فارماسوتيكا ان. في Rapid decomposition of physiologically antagonistic agents of the 2-dopamine receptor
JO2642B1 (en) 2006-12-08 2012-06-17 جانسين فارماسوتيكا ان. في Dopamine 2 receptor antagonists are rapidly hydrolyzed
JO2849B1 (en) 2007-02-13 2015-03-15 جانسين فارماسوتيكا ان. في Dopamine 2 receptor antagonists are rapidly hydrolyzed
EP2148872A1 (fr) * 2007-04-23 2010-02-03 Janssen Pharmaceutica, N.V. Dérivés de pyridine comme antagonistes des récepteurs d2 de la dopamine à dissociation rapide
EP2148873B1 (fr) 2007-04-23 2012-08-29 Janssen Pharmaceutica, N.V. Dérivés de 4-alkoxypyridazine en tant qu'antagonistes du récepteur 2 de la dopamine à dissociation rapide
CN101663299A (zh) 2007-04-23 2010-03-03 詹森药业有限公司 作为快速解离性多巴胺2受体拮抗剂的噻(二)唑类化合物
WO2010000456A1 (fr) 2008-07-03 2010-01-07 Janssen Pharmaceutica Nv 6-(1-pipérazinyl)-pyridazines substituées comme antagonistes du récepteur 5-ht<sb>6</sb>
JP5457450B2 (ja) 2008-07-31 2014-04-02 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 迅速解離性ドーパミン２受容体拮抗薬としてのピペラジン−１−イル−トリフルオロメチル−置換−ピリジン

Also Published As

Publication number Publication date
DK150478C (da) 1987-10-05
IE43802B1 (en) 1981-06-03
NL187267B (nl) 1991-03-01
AU1787876A (en) 1978-03-23
SE7610501L (sv) 1977-03-24
IL50522A0 (en) 1976-11-30
SE427839B (sv) 1983-05-09
ES451768A1 (es) 1978-05-01
AT363935B (de) 1981-09-10
NL187267C (nl) 1991-08-01
HU172964B (hu) 1979-01-28
NZ181972A (en) 1978-07-28
IT1073893B (it) 1985-04-17
FI762698A (fr) 1977-03-24
LU75837A1 (fr) 1977-05-04
PL117323B1 (en) 1981-07-31
JPS6016417B2 (ja) 1985-04-25
DE2642856A1 (de) 1977-03-24
JPS5239683A (en) 1977-03-28
GB1539473A (en) 1979-01-31
CS222663B2 (en) 1983-07-29
NO763054L (no) 1977-03-24
DE2642856C2 (fr) 1990-06-21
IE43802L (en) 1977-03-23
PL192578A1 (pl) 1979-02-26
ATA702976A (de) 1981-02-15
YU39973B (en) 1985-06-30
DK427876A (da) 1977-03-24
PT65631B (en) 1978-07-05
GR58469B (en) 1977-10-14
YU233676A (en) 1983-01-21
FR2325377A1 (fr) 1977-04-22
FI61482C (fi) 1982-08-10
FI61482B (fi) 1982-04-30
IL50522A (en) 1979-09-30
BG27543A3 (en) 1979-11-12
PT65631A (en) 1976-10-01
AU510029B2 (en) 1980-06-05
FR2325377B1 (fr) 1980-04-18
NL7610513A (nl) 1977-03-25
CH628623A5 (en) 1982-03-15
DK150478B (da) 1987-03-09
PH12497A (en) 1979-04-05
SU747424A3 (ru) 1980-07-23
NO147672C (no) 1983-05-25
RO70079A (fr) 1982-10-26
NO147672B (no) 1983-02-14

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