CA1062717A - 1-aryloxy-2-hydroxy-3-alkinylaminopropanes and processes for production thereof - Google Patents

1-aryloxy-2-hydroxy-3-alkinylaminopropanes and processes for production thereof

Info

Publication number
CA1062717A
CA1062717A CA193,683A CA193683A CA1062717A CA 1062717 A CA1062717 A CA 1062717A CA 193683 A CA193683 A CA 193683A CA 1062717 A CA1062717 A CA 1062717A
Authority
CA
Canada
Prior art keywords
group
carbon atoms
formula
compounds
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA193,683A
Other languages
English (en)
French (fr)
Other versions
CA193683S (en
Inventor
Herbert Koppe
Werner Kummer
Helmut Stahle
Gojko Muacevic
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim GmbH
Original Assignee
Boehringer Ingelheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2309887A external-priority patent/DE2309887C2/de
Priority claimed from DE19742403809 external-priority patent/DE2403809C2/de
Application filed by Boehringer Ingelheim GmbH filed Critical Boehringer Ingelheim GmbH
Application granted granted Critical
Publication of CA1062717A publication Critical patent/CA1062717A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/32—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
    • C07C275/34—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms having nitrogen atoms of urea groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CA193,683A 1973-02-28 1974-02-27 1-aryloxy-2-hydroxy-3-alkinylaminopropanes and processes for production thereof Expired CA1062717A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2309887A DE2309887C2 (de) 1973-02-28 1973-02-28 1-Aryloxy-2-hydroxy-3-alkinylaminopropan-Derivate und deren physiologisch verträgliche Säureadditionssalze, pharmazeutische Präparate und Herstellungsverfahren für die Verbindungen
DE19742403809 DE2403809C2 (de) 1974-01-26 1974-01-26 1-Aryloxy-2-hydroxy-3-alkinylaminopropane und Verfahren zu ihrer Herstellung und pharmazeutische Präparate

Publications (1)

Publication Number Publication Date
CA1062717A true CA1062717A (en) 1979-09-18

Family

ID=25764753

Family Applications (1)

Application Number Title Priority Date Filing Date
CA193,683A Expired CA1062717A (en) 1973-02-28 1974-02-27 1-aryloxy-2-hydroxy-3-alkinylaminopropanes and processes for production thereof

Country Status (24)

Country Link
US (1) US3925446A (ja)
JP (1) JPS594417B2 (ja)
AT (1) AT330150B (ja)
BG (7) BG20335A3 (ja)
CA (1) CA1062717A (ja)
CH (7) CH605690A5 (ja)
CS (1) CS186263B2 (ja)
DD (1) DD110652A5 (ja)
DK (1) DK143128C (ja)
ES (7) ES423466A1 (ja)
FI (1) FI62054C (ja)
FR (1) FR2218900B1 (ja)
GB (1) GB1450287A (ja)
HU (1) HU168598B (ja)
IE (1) IE39482B1 (ja)
IL (1) IL44301A (ja)
MX (2) MX4592E (ja)
NL (1) NL169733C (ja)
NO (1) NO138062C (ja)
PH (1) PH9722A (ja)
PL (2) PL93591B1 (ja)
SE (1) SE411897B (ja)
SU (1) SU793381A3 (ja)
YU (2) YU50074A (ja)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4038313A (en) * 1970-01-08 1977-07-26 Ciba-Geigy Corporation Cycloalkylureido phenoxy propanolamines
US4078146A (en) * 1972-07-06 1978-03-07 Aktiebolaget Hassle Phenoxy propanolamines
US4035420A (en) * 1972-07-06 1977-07-12 Aktiebolaget Hassle Substituted ureido alkylene phenoxy propanolamines
GB1374366A (en) * 1972-07-21 1974-11-20 Science Union & Cie Propanol derivatives and a process for their preparation
AT334385B (de) * 1973-12-20 1976-01-10 Chemie Linz Ag Verfahren zur herstellung von neuen phenoxypropylaminderivaten und deren salzen
US4243681A (en) * 1977-10-11 1981-01-06 Mead Johnson & Company Alkylthiophenoxypropanolamines and pharmaceutical compositions and uses thereof
DE2805404A1 (de) * 1978-02-09 1979-08-16 Merck Patent Gmbh 1-aryloxy-3-nitratoalkylamino-2-propanole und verfahren zu ihrer herstellung
DE3009047A1 (de) * 1980-03-08 1981-09-24 C.H. Boehringer Sohn, 6507 Ingelheim Neue l-(acylamino-aryloxy-)2-hydroxy-3-alkinylaminopropane und verfahren zu ihrer herstellung
DE3009036A1 (de) * 1980-03-08 1981-09-24 C.H. Boehringer Sohn, 6507 Ingelheim Neue l-(acylamino-aryloxy-)2-hydroxy-3-alkinylaminopropane und verfahren zu ihrer herstellung
US4387103A (en) * 1980-11-28 1983-06-07 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
US4454154A (en) * 1981-06-23 1984-06-12 American Hospital Supply Corporation Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents
US4559359A (en) * 1981-06-23 1985-12-17 American Hospital Supply Corporation Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents
DE3248835A1 (de) * 1981-06-23 1983-06-30 American Hospital Supply Corp Zusammensetzungen fuer die behandlung von glaukom
US4455317A (en) * 1981-06-23 1984-06-19 American Hospital Supply Corporation Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents
US4578403A (en) * 1981-06-23 1986-03-25 American Hospital Supply Corporation Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents
DE3133719A1 (de) * 1981-08-26 1983-03-10 Boehringer Ingelheim KG, 6507 Ingelheim Neue 1-aryloxy-3-alkinylamino-2-propanole und verfahren zu ihrer herstellung
JPH02130007U (ja) * 1989-03-31 1990-10-26
BRPI0507670A (pt) * 2004-02-13 2007-07-17 Warner Lambert Co moduladores do receptor de androgênio
JP5838114B2 (ja) 2012-04-02 2015-12-24 株式会社リガク Ｘ線トポグラフィ装置

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3459782A (en) * 1963-08-26 1969-08-05 Boehringer Sohn Ingelheim 1-substituted phenoxy-2-hydroxy-3-isopropylamino-propanes
GB1199037A (en) * 1967-09-27 1970-07-15 Ici Ltd Alkanolamine Derivatives
US3541130A (en) * 1967-02-06 1970-11-17 Boehringer Sohn Ingelheim 1-(cyanophenoxy)-2-hydroxy-3-tert.-butylamine propanes

Also Published As

Publication number Publication date
JPS594417B2 (ja) 1984-01-30
PL91560B1 (ja) 1977-03-31
DK143128B (da) 1981-06-29
IE39482L (en) 1974-08-28
CH605639A5 (ja) 1978-10-13
BG20566A3 (ja) 1975-12-05
IE39482B1 (en) 1978-10-25
AU6606574A (en) 1975-08-28
YU109580A (en) 1982-06-30
BG21394A3 (ja) 1976-05-20
PL93591B1 (ja) 1977-06-30
CH605637A5 (ja) 1978-10-13
BG20564A3 (ja) 1975-12-05
BG20565A3 (ja) 1975-12-05
FI62054B (fi) 1982-07-30
NL169733C (nl) 1982-08-16
DK143128C (da) 1981-11-16
FI62054C (fi) 1982-11-10
ES436313A1 (es) 1977-01-01
US3925446A (en) 1975-12-09
PH9722A (en) 1976-02-27
NO740670L (no) 1974-08-29
CH605638A5 (ja) 1978-10-13
BG21208A3 (ja) 1976-03-20
ES436315A1 (es) 1977-01-01
CH605689A5 (ja) 1978-10-13
CH605690A5 (ja) 1978-10-13
FR2218900A1 (ja) 1974-09-20
AT330150B (de) 1976-06-10
GB1450287A (en) 1976-09-22
DD110652A5 (de) 1975-01-05
CH605636A5 (ja) 1978-10-13
NL7402704A (ja) 1974-08-30
FR2218900B1 (ja) 1978-01-06
CH605691A5 (ja) 1978-10-13
ATA104774A (de) 1975-09-15
ES436311A1 (es) 1977-01-01
MX4592E (es) 1982-06-25
ES436312A1 (es) 1977-01-01
NL169733B (nl) 1982-03-16
ES423466A1 (es) 1977-01-16
SE411897B (sv) 1980-02-11
ES436314A1 (es) 1977-01-01
BG20335A3 (ja) 1975-11-05
ES436316A1 (es) 1977-01-01
BG20334A3 (ja) 1975-11-05
NO138062B (no) 1978-03-13
HU168598B (ja) 1976-06-28
SU793381A3 (ru) 1980-12-30
MX4588E (es) 1982-06-25
YU50074A (en) 1982-06-30
CS186263B2 (en) 1978-11-30
NO138062C (no) 1978-06-21
IL44301A (en) 1977-03-31
JPS5024232A (ja) 1975-03-15
IL44301A0 (en) 1974-06-30

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