IE39482L - Propanolamines - Google Patents

Propanolamines

Info

Publication number
IE39482L
IE39482L IE740428A IE42874A IE39482L IE 39482 L IE39482 L IE 39482L IE 740428 A IE740428 A IE 740428A IE 42874 A IE42874 A IE 42874A IE 39482 L IE39482 L IE 39482L
Authority
IE
Ireland
Prior art keywords
properties
compounds
us3925446a
andrenolytic
3bond
Prior art date
Application number
IE740428A
Other versions
IE39482B1 (en
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2309887A external-priority patent/DE2309887C2/en
Priority claimed from DE19742403809 external-priority patent/DE2403809C2/en
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of IE39482L publication Critical patent/IE39482L/en
Publication of IE39482B1 publication Critical patent/IE39482B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/32—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
    • C07C275/34—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms having nitrogen atoms of urea groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Racemic and optically active compounds of the formula R4 O-CH2-CHOH-CH2-NH-C-C 3BOND CH R5 wherein R1, R2, R3, R4 and R5 are hydrogen or various substituents, and their physiologically compatible acid addition salts, as well as the process for producing the compounds, therapeutic compositions and methods. The 1-aryloxy-2-hydroxy-3-alkynylamino-propanes have andrenolytic properties and blood-pressure reducing properties. [US3925446A]
IE428/74A 1973-02-28 1974-02-28 Propanolamines IE39482B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2309887A DE2309887C2 (en) 1973-02-28 1973-02-28 1-aryloxy-2-hydroxy-3-alkynylaminopropane derivatives and their physiologically acceptable acid addition salts, pharmaceutical preparations and manufacturing processes for the compounds
DE19742403809 DE2403809C2 (en) 1974-01-26 1974-01-26 1-Aryloxy-2-hydroxy-3-alkynylaminopropanes and processes for their manufacture and pharmaceutical preparations

Publications (2)

Publication Number Publication Date
IE39482L true IE39482L (en) 1974-08-28
IE39482B1 IE39482B1 (en) 1978-10-25

Family

ID=25764753

Family Applications (1)

Application Number Title Priority Date Filing Date
IE428/74A IE39482B1 (en) 1973-02-28 1974-02-28 Propanolamines

Country Status (24)

Country Link
US (1) US3925446A (en)
JP (1) JPS594417B2 (en)
AT (1) AT330150B (en)
BG (7) BG21208A3 (en)
CA (1) CA1062717A (en)
CH (7) CH605638A5 (en)
CS (1) CS186263B2 (en)
DD (1) DD110652A5 (en)
DK (1) DK143128C (en)
ES (7) ES423466A1 (en)
FI (1) FI62054C (en)
FR (1) FR2218900B1 (en)
GB (1) GB1450287A (en)
HU (1) HU168598B (en)
IE (1) IE39482B1 (en)
IL (1) IL44301A (en)
MX (2) MX4592E (en)
NL (1) NL169733C (en)
NO (1) NO138062C (en)
PH (1) PH9722A (en)
PL (2) PL91560B1 (en)
SE (1) SE411897B (en)
SU (1) SU793381A3 (en)
YU (2) YU50074A (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4038313A (en) * 1970-01-08 1977-07-26 Ciba-Geigy Corporation Cycloalkylureido phenoxy propanolamines
US4035420A (en) * 1972-07-06 1977-07-12 Aktiebolaget Hassle Substituted ureido alkylene phenoxy propanolamines
US4078146A (en) * 1972-07-06 1978-03-07 Aktiebolaget Hassle Phenoxy propanolamines
GB1374366A (en) * 1972-07-21 1974-11-20 Science Union & Cie Propanol derivatives and a process for their preparation
AT334385B (en) * 1973-12-20 1976-01-10 Chemie Linz Ag PROCESS FOR THE PREPARATION OF NEW PHENOXYPROPYLAMINE DERIVATIVES AND THEIR SALTS
US4243681A (en) * 1977-10-11 1981-01-06 Mead Johnson & Company Alkylthiophenoxypropanolamines and pharmaceutical compositions and uses thereof
DE2805404A1 (en) * 1978-02-09 1979-08-16 Merck Patent Gmbh 1-ARYLOXY-3-NITRATOALKYLAMINO-2-PROPANOLS AND METHOD FOR THE PRODUCTION THEREOF
DE3009047A1 (en) * 1980-03-08 1981-09-24 C.H. Boehringer Sohn, 6507 Ingelheim NEW L- (ACYLAMINO-ARYLOXY-) 2-HYDROXY-3-ALKINYLAMINOPROPANES AND METHOD FOR THEIR PRODUCTION
DE3009036A1 (en) * 1980-03-08 1981-09-24 C.H. Boehringer Sohn, 6507 Ingelheim NEW L- (ACYLAMINO-ARYLOXY-) 2-HYDROXY-3-ALKINYLAMINOPROPANES AND METHOD FOR THEIR PRODUCTION
US4387103A (en) * 1980-11-28 1983-06-07 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
DE3248835A1 (en) * 1981-06-23 1983-06-30 American Hospital Supply Corp COMPOSITIONS FOR TREATING GLAUCOMA
US4455317A (en) * 1981-06-23 1984-06-19 American Hospital Supply Corporation Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents
US4578403A (en) * 1981-06-23 1986-03-25 American Hospital Supply Corporation Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents
US4559359A (en) * 1981-06-23 1985-12-17 American Hospital Supply Corporation Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents
US4454154A (en) * 1981-06-23 1984-06-12 American Hospital Supply Corporation Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents
DE3133719A1 (en) * 1981-08-26 1983-03-10 Boehringer Ingelheim KG, 6507 Ingelheim NEW 1-ARYLOXY-3-ALKINYLAMINO-2-PROPANOLS AND METHOD FOR THE PRODUCTION THEREOF
JPH02130007U (en) * 1989-03-31 1990-10-26
CA2554696C (en) * 2004-02-13 2009-06-30 Warner-Lambert Company Llc Androgen receptor modulators
JP5838114B2 (en) 2012-04-02 2015-12-24 株式会社リガク X-ray topography equipment

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3459782A (en) * 1963-08-26 1969-08-05 Boehringer Sohn Ingelheim 1-substituted phenoxy-2-hydroxy-3-isopropylamino-propanes
GB1199037A (en) * 1967-09-27 1970-07-15 Ici Ltd Alkanolamine Derivatives
US3541130A (en) * 1967-02-06 1970-11-17 Boehringer Sohn Ingelheim 1-(cyanophenoxy)-2-hydroxy-3-tert.-butylamine propanes

Also Published As

Publication number Publication date
CH605637A5 (en) 1978-10-13
PL93591B1 (en) 1977-06-30
US3925446A (en) 1975-12-09
HU168598B (en) 1976-06-28
NO138062C (en) 1978-06-21
ES436316A1 (en) 1977-01-01
AT330150B (en) 1976-06-10
IL44301A (en) 1977-03-31
DK143128B (en) 1981-06-29
SU793381A3 (en) 1980-12-30
NO740670L (en) 1974-08-29
MX4592E (en) 1982-06-25
SE411897B (en) 1980-02-11
NO138062B (en) 1978-03-13
BG20566A3 (en) 1975-12-05
CH605638A5 (en) 1978-10-13
DD110652A5 (en) 1975-01-05
ES423466A1 (en) 1977-01-16
NL7402704A (en) 1974-08-30
NL169733B (en) 1982-03-16
GB1450287A (en) 1976-09-22
FI62054C (en) 1982-11-10
JPS5024232A (en) 1975-03-15
FR2218900B1 (en) 1978-01-06
DK143128C (en) 1981-11-16
AU6606574A (en) 1975-08-28
YU109580A (en) 1982-06-30
BG20565A3 (en) 1975-12-05
FI62054B (en) 1982-07-30
ES436314A1 (en) 1977-01-01
BG20335A3 (en) 1975-11-05
CH605689A5 (en) 1978-10-13
BG20564A3 (en) 1975-12-05
IL44301A0 (en) 1974-06-30
PL91560B1 (en) 1977-03-31
ES436311A1 (en) 1977-01-01
ES436312A1 (en) 1977-01-01
CS186263B2 (en) 1978-11-30
FR2218900A1 (en) 1974-09-20
CA1062717A (en) 1979-09-18
CH605690A5 (en) 1978-10-13
ES436315A1 (en) 1977-01-01
CH605639A5 (en) 1978-10-13
CH605691A5 (en) 1978-10-13
ES436313A1 (en) 1977-01-01
PH9722A (en) 1976-02-27
BG20334A3 (en) 1975-11-05
JPS594417B2 (en) 1984-01-30
ATA104774A (en) 1975-09-15
MX4588E (en) 1982-06-25
YU50074A (en) 1982-06-30
CH605636A5 (en) 1978-10-13
BG21394A3 (en) 1976-05-20
IE39482B1 (en) 1978-10-25
BG21208A3 (en) 1976-03-20
NL169733C (en) 1982-08-16

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