GB1450287A - Propanolamines - Google Patents
PropanolaminesInfo
- Publication number
- GB1450287A GB1450287A GB894974A GB894974A GB1450287A GB 1450287 A GB1450287 A GB 1450287A GB 894974 A GB894974 A GB 894974A GB 894974 A GB894974 A GB 894974A GB 1450287 A GB1450287 A GB 1450287A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- alkoxy
- halogen
- acyl
- acyloxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/32—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
- C07C275/34—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms having nitrogen atoms of urea groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
1450287 Pharmaceutical compositions BOBHRINGER INGELHElM GmbH 27 Feb 1974 [28 Feb 1973 26 Jan 1974] 8949/74 Heading A5B [Also in Division C2] Pharmaceutical compositions comprise a compound of the general formula R 1 = H, halogen, NO 2 , C 1-5 alkyl, C 1-4 alkoxy, C 2-5 alkenyl or alkynyl, C 1-6 alkylamino, di(C 1-6 alkyl)amino, C 1-6 alkoxy-(C 1-6 alkyl), C 1-6 alkyl- or di(C 1-6 alkyl)-amino- (C 1-6 alkyl), (CH 2 ) 0-3 -(CN, NH 2 or OH), COOH C 2-5 alkoxycarbonyl, C 3-6 alkenyloxy or alkylnyloxy, optionally substituted aliphatic or araliphatic acyl, acyloxy or acrylamino wherein each aliphatic moiety contains 1-6 carbon atoms, aromatic acyl, acyloxy or acylamino, C 3-7 cycloalkyl, QCONR 7 R 8 : Q = single bond, O, NH, CH 2 , CH 2 NH: R 7 , # =H, C 1-6 alkyl, aryl or aryloxy optionally bearing one or more substituents selected from halogen, alkyl, alkoxy, NO 2 ,CN, COOH, or NR 7 R 8 = heterocyclic group; R 2 = H, halogen, CN, NH 2 , NO 2 , C 1-4 alkyl or alkoxy, C 2-4 acyl or alkenyl, or R 1+2 = 3. 4-methylenedioxy: R 3 = H, halogen, C 1-4 alkyl or alkoxy. or R 2 +3 (bonded to adjacent carbon atoms) = (CH 2 ) 3-5 or -CH=CH-CH=CH-: R 4 = H, C 1-3 alkyl; R = C 1-3 alkyl, or R 4+5 = (CH 2 ) 4-6 or acid addition salt thereof, with or without a further active ingredient, e.g. coronary detectors, sympathicomimetics, cardiac glycosides, tranquilisers), in association with a carrier. The primary active ingredients are adrelytics and hypotensive agents.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2309887A DE2309887C2 (en) | 1973-02-28 | 1973-02-28 | 1-aryloxy-2-hydroxy-3-alkynylaminopropane derivatives and their physiologically acceptable acid addition salts, pharmaceutical preparations and manufacturing processes for the compounds |
| DE19742403809 DE2403809C2 (en) | 1974-01-26 | 1974-01-26 | 1-Aryloxy-2-hydroxy-3-alkynylaminopropanes and processes for their manufacture and pharmaceutical preparations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1450287A true GB1450287A (en) | 1976-09-22 |
Family
ID=25764753
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB894974A Expired GB1450287A (en) | 1973-02-28 | 1974-02-27 | Propanolamines |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US3925446A (en) |
| JP (1) | JPS594417B2 (en) |
| AT (1) | AT330150B (en) |
| BG (7) | BG20564A3 (en) |
| CA (1) | CA1062717A (en) |
| CH (7) | CH605690A5 (en) |
| CS (1) | CS186263B2 (en) |
| DD (1) | DD110652A5 (en) |
| DK (1) | DK143128C (en) |
| ES (7) | ES423466A1 (en) |
| FI (1) | FI62054C (en) |
| FR (1) | FR2218900B1 (en) |
| GB (1) | GB1450287A (en) |
| HU (1) | HU168598B (en) |
| IE (1) | IE39482B1 (en) |
| IL (1) | IL44301A (en) |
| MX (2) | MX4592E (en) |
| NL (1) | NL169733C (en) |
| NO (1) | NO138062C (en) |
| PH (1) | PH9722A (en) |
| PL (2) | PL91560B1 (en) |
| SE (1) | SE411897B (en) |
| SU (1) | SU793381A3 (en) |
| YU (2) | YU50074A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1982001869A1 (en) * | 1980-11-28 | 1982-06-10 | Hospital Supply Corp American | Method for treatment or prophylaxis of cardiac disorders |
| DE3248835A1 (en) * | 1981-06-23 | 1983-06-30 | American Hospital Supply Corp | COMPOSITIONS FOR TREATING GLAUCOMA |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4038313A (en) * | 1970-01-08 | 1977-07-26 | Ciba-Geigy Corporation | Cycloalkylureido phenoxy propanolamines |
| US4035420A (en) * | 1972-07-06 | 1977-07-12 | Aktiebolaget Hassle | Substituted ureido alkylene phenoxy propanolamines |
| US4078146A (en) * | 1972-07-06 | 1978-03-07 | Aktiebolaget Hassle | Phenoxy propanolamines |
| GB1374366A (en) * | 1972-07-21 | 1974-11-20 | Science Union & Cie | Propanol derivatives and a process for their preparation |
| AT334385B (en) * | 1973-12-20 | 1976-01-10 | Chemie Linz Ag | PROCESS FOR THE PREPARATION OF NEW PHENOXYPROPYLAMINE DERIVATIVES AND THEIR SALTS |
| US4243681A (en) * | 1977-10-11 | 1981-01-06 | Mead Johnson & Company | Alkylthiophenoxypropanolamines and pharmaceutical compositions and uses thereof |
| DE2805404A1 (en) * | 1978-02-09 | 1979-08-16 | Merck Patent Gmbh | 1-ARYLOXY-3-NITRATOALKYLAMINO-2-PROPANOLS AND METHOD FOR THE PRODUCTION THEREOF |
| DE3009036A1 (en) * | 1980-03-08 | 1981-09-24 | C.H. Boehringer Sohn, 6507 Ingelheim | NEW L- (ACYLAMINO-ARYLOXY-) 2-HYDROXY-3-ALKINYLAMINOPROPANES AND METHOD FOR THEIR PRODUCTION |
| DE3009047A1 (en) * | 1980-03-08 | 1981-09-24 | C.H. Boehringer Sohn, 6507 Ingelheim | NEW L- (ACYLAMINO-ARYLOXY-) 2-HYDROXY-3-ALKINYLAMINOPROPANES AND METHOD FOR THEIR PRODUCTION |
| US4455317A (en) * | 1981-06-23 | 1984-06-19 | American Hospital Supply Corporation | Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents |
| US4578403A (en) * | 1981-06-23 | 1986-03-25 | American Hospital Supply Corporation | Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents |
| US4454154A (en) * | 1981-06-23 | 1984-06-12 | American Hospital Supply Corporation | Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents |
| US4559359A (en) * | 1981-06-23 | 1985-12-17 | American Hospital Supply Corporation | Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents |
| DE3133719A1 (en) * | 1981-08-26 | 1983-03-10 | Boehringer Ingelheim KG, 6507 Ingelheim | NEW 1-ARYLOXY-3-ALKINYLAMINO-2-PROPANOLS AND METHOD FOR THE PRODUCTION THEREOF |
| JPH02130007U (en) * | 1989-03-31 | 1990-10-26 | ||
| AP2006003700A0 (en) * | 2004-02-13 | 2006-08-31 | Warner Lambert Co | Androgen receptor modulators |
| JP5838114B2 (en) | 2012-04-02 | 2015-12-24 | 株式会社リガク | X-ray topography equipment |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3459782A (en) * | 1963-08-26 | 1969-08-05 | Boehringer Sohn Ingelheim | 1-substituted phenoxy-2-hydroxy-3-isopropylamino-propanes |
| GB1199037A (en) * | 1967-09-27 | 1970-07-15 | Ici Ltd | Alkanolamine Derivatives |
| US3541130A (en) * | 1967-02-06 | 1970-11-17 | Boehringer Sohn Ingelheim | 1-(cyanophenoxy)-2-hydroxy-3-tert.-butylamine propanes |
-
1974
- 1974-02-11 AT AT104774A patent/AT330150B/en not_active IP Right Cessation
- 1974-02-21 ES ES423466A patent/ES423466A1/en not_active Expired
- 1974-02-22 US US444713A patent/US3925446A/en not_active Expired - Lifetime
- 1974-02-25 FI FI544/74A patent/FI62054C/en active
- 1974-02-25 CS CS7400001369A patent/CS186263B2/en unknown
- 1974-02-26 BG BG025901A patent/BG20564A3/en unknown
- 1974-02-26 BG BG026939A patent/BG21208A3/en unknown
- 1974-02-26 BG BG026938A patent/BG20334A3/en unknown
- 1974-02-26 BG BG026942A patent/BG20565A3/en unknown
- 1974-02-26 BG BG026941A patent/BG20335A3/en unknown
- 1974-02-26 DD DD176809A patent/DD110652A5/en unknown
- 1974-02-26 HU HUBO1487A patent/HU168598B/hu unknown
- 1974-02-26 BG BG026943A patent/BG20566A3/en unknown
- 1974-02-26 BG BG026940A patent/BG21394A3/en unknown
- 1974-02-27 CH CH1485977A patent/CH605690A5/xx not_active IP Right Cessation
- 1974-02-27 CH CH278074A patent/CH605636A5/xx not_active IP Right Cessation
- 1974-02-27 CH CH1485477A patent/CH605637A5/xx not_active IP Right Cessation
- 1974-02-27 MX MX745493U patent/MX4592E/en unknown
- 1974-02-27 MX MX745489U patent/MX4588E/en unknown
- 1974-02-27 NO NO740670A patent/NO138062C/en unknown
- 1974-02-27 DK DK105174A patent/DK143128C/en not_active IP Right Cessation
- 1974-02-27 SE SE7402622A patent/SE411897B/en not_active IP Right Cessation
- 1974-02-27 PL PL1974169115A patent/PL91560B1/pl unknown
- 1974-02-27 YU YU00500/74A patent/YU50074A/en unknown
- 1974-02-27 CH CH1485677A patent/CH605689A5/xx not_active IP Right Cessation
- 1974-02-27 CH CH1486077A patent/CH605691A5/xx not_active IP Right Cessation
- 1974-02-27 PL PL1974183356A patent/PL93591B1/pl unknown
- 1974-02-27 CA CA193,683A patent/CA1062717A/en not_active Expired
- 1974-02-27 CH CH1485577A patent/CH605638A5/xx not_active IP Right Cessation
- 1974-02-27 IL IL44301A patent/IL44301A/en unknown
- 1974-02-27 PH PH15555*UA patent/PH9722A/en unknown
- 1974-02-27 JP JP49023221A patent/JPS594417B2/en not_active Expired
- 1974-02-27 GB GB894974A patent/GB1450287A/en not_active Expired
- 1974-02-28 FR FR7406835A patent/FR2218900B1/fr not_active Expired
- 1974-02-28 IE IE428/74A patent/IE39482B1/en unknown
- 1974-02-28 NL NLAANVRAGE7402704,A patent/NL169733C/en not_active IP Right Cessation
- 1974-08-27 CH CH1485877A patent/CH605639A5/xx not_active IP Right Cessation
-
1975
- 1975-01-29 SU SU752100046A patent/SU793381A3/en active
- 1975-04-04 ES ES436313A patent/ES436313A1/en not_active Expired
- 1975-04-04 ES ES436315A patent/ES436315A1/en not_active Expired
- 1975-04-04 ES ES436314A patent/ES436314A1/en not_active Expired
- 1975-04-04 ES ES436316A patent/ES436316A1/en not_active Expired
- 1975-04-04 ES ES436312A patent/ES436312A1/en not_active Expired
- 1975-04-04 ES ES436311A patent/ES436311A1/en not_active Expired
-
1980
- 1980-04-22 YU YU01095/80A patent/YU109580A/en unknown
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1982001869A1 (en) * | 1980-11-28 | 1982-06-10 | Hospital Supply Corp American | Method for treatment or prophylaxis of cardiac disorders |
| DE3248835A1 (en) * | 1981-06-23 | 1983-06-30 | American Hospital Supply Corp | COMPOSITIONS FOR TREATING GLAUCOMA |
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |