SE7708686L - INTERMEDIATE PRODUCTS AND PROCEDURES FOR THE MANUFACTURE OF IT - Google Patents
INTERMEDIATE PRODUCTS AND PROCEDURES FOR THE MANUFACTURE OF ITInfo
- Publication number
- SE7708686L SE7708686L SE7708686A SE7708686A SE7708686L SE 7708686 L SE7708686 L SE 7708686L SE 7708686 A SE7708686 A SE 7708686A SE 7708686 A SE7708686 A SE 7708686A SE 7708686 L SE7708686 L SE 7708686L
- Authority
- SE
- Sweden
- Prior art keywords
- phenyl
- beta
- preparation
- acid addition
- glyoxal
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 239000013067 intermediate product Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- OJUGVDODNPJEEC-UHFFFAOYSA-N phenylglyoxal Chemical compound O=CC(=O)C1=CC=CC=C1 OJUGVDODNPJEEC-UHFFFAOYSA-N 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000001766 physiological effect Effects 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
.beta. This invention relates to a new process for the preparation of certain 4-amino-3,5-dihalogeno-phenyl ethanolamines and acid addition salts thereof having valuable physiological properties, in particular an activity on .beta.-receptors. The new process comprises the reduction of the corresponding phenyl-glyoxal or hydrate thereof in the presence of an appropiate amine and the optional subsequent conversion of the compound thus prepared into an acid addition salt thereof. The phenyl-glyoxal derivatives used as starting materials are new compounds and constitute a further feature of the invention. Processes for their preparation are given.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2354959A DE2354959C3 (en) | 1973-11-02 | 1973-11-02 | New process for the preparation of 4-amino-3,5 dihalo phenyl-athanolamines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7708686L true SE7708686L (en) | 1977-07-28 |
| SE430057B SE430057B (en) | 1983-10-17 |
Family
ID=5897109
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7413786A SE411546B (en) | 1973-11-02 | 1974-11-01 | PROCEDURE FOR PREPARING 4-AMINO-3,5-DIHALOGENPHENYLETANOLAMINES |
| SE7708686A SE430057B (en) | 1973-11-02 | 1977-07-28 | INTERMEDIATE FOR USE FOR PREPARATION OF 4-AMINO-3,5-DIHALOGENPHENYLETANOLAMINES |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7413786A SE411546B (en) | 1973-11-02 | 1974-11-01 | PROCEDURE FOR PREPARING 4-AMINO-3,5-DIHALOGENPHENYLETANOLAMINES |
Country Status (19)
| Country | Link |
|---|---|
| JP (1) | JPS5855133B2 (en) |
| AT (1) | AT340394B (en) |
| BG (1) | BG23746A3 (en) |
| CA (1) | CA1041545A (en) |
| CH (1) | CH609040A5 (en) |
| CS (1) | CS175487B2 (en) |
| DD (1) | DD116599A5 (en) |
| DE (1) | DE2354959C3 (en) |
| DK (1) | DK134484C (en) |
| ES (1) | ES430587A1 (en) |
| FI (2) | FI60858C (en) |
| HU (1) | HU168133B (en) |
| NL (1) | NL7414223A (en) |
| NO (1) | NO139479C (en) |
| PL (1) | PL96537B1 (en) |
| RO (1) | RO68703A (en) |
| SE (2) | SE411546B (en) |
| SU (1) | SU549079A3 (en) |
| YU (1) | YU36918B (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3714484A1 (en) * | 1987-04-30 | 1988-11-10 | Bayer Ag | NEW AMINOPHENYLETHYLAMINE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF AND THEIR USE AS A PERFORMANCE PROVIDER |
| US5552442A (en) * | 1987-09-15 | 1996-09-03 | The Rowett Research Institute | Therapeutic applications of clenbuterol |
| US5530029A (en) * | 1987-09-15 | 1996-06-25 | The Rowett Research Institute | Therapeutic applications of clenbuterol |
| GB9913083D0 (en) * | 1999-06-04 | 1999-08-04 | Novartis Ag | Organic compounds |
| EP3331848A4 (en) * | 2015-08-06 | 2019-07-17 | Vamsi Labs Ltd. | A process for preparing agonist |
| CN111393311A (en) * | 2020-03-30 | 2020-07-10 | 苏州弘森药业股份有限公司 | Environment-friendly and nontoxic synthesis method of clenbuterol hydrochloride |
-
1973
- 1973-11-02 DE DE2354959A patent/DE2354959C3/en not_active Expired
-
1974
- 1974-09-19 FI FI2736/74A patent/FI60858C/en active
- 1974-09-20 AT AT756374A patent/AT340394B/en not_active IP Right Cessation
- 1974-10-02 ES ES430587A patent/ES430587A1/en not_active Expired
- 1974-10-18 CS CS7165A patent/CS175487B2/cs unknown
- 1974-10-22 DK DK552274A patent/DK134484C/en active
- 1974-10-24 YU YU2850/74A patent/YU36918B/en unknown
- 1974-10-25 SU SU2069690A patent/SU549079A3/en active
- 1974-10-29 BG BG028068A patent/BG23746A3/en unknown
- 1974-10-30 DD DD182043A patent/DD116599A5/xx unknown
- 1974-10-30 CH CH1454274A patent/CH609040A5/en not_active IP Right Cessation
- 1974-10-31 NL NL7414223A patent/NL7414223A/en not_active Application Discontinuation
- 1974-10-31 RO RO7480380A patent/RO68703A/en unknown
- 1974-10-31 PL PL1974175272A patent/PL96537B1/en unknown
- 1974-11-01 NO NO743946A patent/NO139479C/en unknown
- 1974-11-01 JP JP49126469A patent/JPS5855133B2/en not_active Expired
- 1974-11-01 SE SE7413786A patent/SE411546B/en not_active IP Right Cessation
- 1974-11-01 HU HUTO987A patent/HU168133B/en unknown
- 1974-11-01 CA CA212,850A patent/CA1041545A/en not_active Expired
-
1977
- 1977-07-28 SE SE7708686A patent/SE430057B/en not_active IP Right Cessation
-
1980
- 1980-03-20 FI FI800860A patent/FI800860A7/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NO743946L (en) | 1975-05-26 |
| NL7414223A (en) | 1975-05-07 |
| ATA756374A (en) | 1977-04-15 |
| SE7413786L (en) | 1975-05-05 |
| CA1041545A (en) | 1978-10-31 |
| SU549079A3 (en) | 1977-02-28 |
| RO68703A (en) | 1981-09-24 |
| NO139479B (en) | 1978-12-11 |
| YU285074A (en) | 1982-06-18 |
| DD116599A5 (en) | 1975-12-05 |
| YU36918B (en) | 1984-08-31 |
| SE430057B (en) | 1983-10-17 |
| SE411546B (en) | 1980-01-14 |
| FI800860A7 (en) | 1981-01-01 |
| AT340394B (en) | 1977-12-12 |
| DK552274A (en) | 1975-06-23 |
| DE2354959B2 (en) | 1979-06-07 |
| BG23746A3 (en) | 1977-10-12 |
| FI60858B (en) | 1981-12-31 |
| CS175487B2 (en) | 1977-05-31 |
| DE2354959A1 (en) | 1975-05-15 |
| DE2354959C3 (en) | 1980-02-07 |
| HU168133B (en) | 1976-02-28 |
| NO139479C (en) | 1979-03-21 |
| FI273674A7 (en) | 1975-05-03 |
| PL96537B1 (en) | 1977-12-31 |
| DK134484B (en) | 1976-11-15 |
| JPS5855133B2 (en) | 1983-12-08 |
| JPS5071637A (en) | 1975-06-13 |
| DK134484C (en) | 1977-04-25 |
| CH609040A5 (en) | 1979-02-15 |
| ES430587A1 (en) | 1976-09-01 |
| FI60858C (en) | 1982-04-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NUG | Patent has lapsed |
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