IE37655L - Derivatives of 1-phenoxy-3-aminopropane-2-ol. - Google Patents
Derivatives of 1-phenoxy-3-aminopropane-2-ol.Info
- Publication number
- IE37655L IE37655L IE730805A IE80573A IE37655L IE 37655 L IE37655 L IE 37655L IE 730805 A IE730805 A IE 730805A IE 80573 A IE80573 A IE 80573A IE 37655 L IE37655 L IE 37655L
- Authority
- IE
- Ireland
- Prior art keywords
- phenoxy
- alkyl
- new derivatives
- propane
- amino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/24—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/50—Ketonic radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The present invention relates to pharmacologically valuable new derivatives of 1-phenoxy-3-amino-propane-2-ol and process for their production. The new derivatives of 1-phenoxy-3-amino-propane-2-ol are suitable for the treatment and prophylaxis of diseases of the heart. Some possess pronounced beta -adrenalytic or anti-arythmic properties. These new derivatives have the structural formula WHEREIN X signifies AND THE PHENYL NUCLEUS I may be mono-, di- or trisubstituted by alkyl, alkenyl, alkinyl, cycloalkyl, cycloalkenyl, alkoxy, alkenyloxy, phenyl, halogen or the radical -NR1R2, in which R1 stands for alkyl or acyl and R2 for hydrogen or alkyl, together with their aldehyde condensation products and their acid addition salts.
[US3940406A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| LU65414 | 1972-05-24 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE37655L true IE37655L (en) | 1973-11-24 |
| IE37655B1 IE37655B1 (en) | 1977-09-14 |
Family
ID=19727058
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE805/73A IE37655B1 (en) | 1972-05-24 | 1973-05-21 | Derivatives of 1-phenoxy-3-amino-propane-2-ol and process for their production |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US3940406A (en) |
| JP (4) | JPS4941380A (en) |
| AR (4) | AR199905A1 (en) |
| AT (4) | AT326659B (en) |
| BE (1) | BE800005A (en) |
| BG (3) | BG20782A3 (en) |
| CA (1) | CA1015357A (en) |
| CH (4) | CH581621A5 (en) |
| CS (4) | CS183702B2 (en) |
| DD (1) | DD106835A5 (en) |
| DE (1) | DE2323354A1 (en) |
| ES (4) | ES415046A1 (en) |
| FR (1) | FR2185411B1 (en) |
| GB (1) | GB1409959A (en) |
| HU (1) | HU165663B (en) |
| IE (1) | IE37655B1 (en) |
| IL (1) | IL42333A (en) |
| LU (1) | LU65414A1 (en) |
| NL (1) | NL7306691A (en) |
| PH (3) | PH9827A (en) |
| PL (1) | PL91588B1 (en) |
| RO (2) | RO64607A (en) |
| SE (1) | SE399425B (en) |
| SU (4) | SU489309A3 (en) |
| ZA (1) | ZA733513B (en) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4088764A (en) * | 1973-12-27 | 1978-05-09 | Cassella Farbwerke Mainkur Aktiengesellschaft | Pharmaceutically active derivatives of 1-phenoxy-3-amino-propan-2-ol |
| US4066768A (en) * | 1973-12-27 | 1978-01-03 | Cassella Farbwerke Mainkur Aktiengesellschaft | Derivatives of 1-phenoxy-3-amino-propan-2-ol |
| US4139623A (en) * | 1974-05-14 | 1979-02-13 | C-G Corp. | Cyclic-substituted derivatives of 1-amino-2-propanol |
| CH591448A5 (en) * | 1974-05-14 | 1977-09-15 | Ciba Geigy Ag | |
| JPS528043A (en) * | 1975-07-10 | 1977-01-21 | Toagosei Chem Ind Co Ltd | Adhesive |
| US4097490A (en) * | 1975-09-25 | 1978-06-27 | Merck & Co., Inc. | Pyroglutamic acid salts of t-butylamino-2,3-dihydroxypropane |
| US4060601A (en) * | 1976-06-15 | 1977-11-29 | Merck & Co., Inc. | Certain lower-alkyl amino-2'-hydroxy-propoxy pyridines |
| JPH0774714B2 (en) * | 1986-11-18 | 1995-08-09 | 中野冷機株式会社 | Open showcase temperature controller |
| JP2858389B2 (en) * | 1994-02-21 | 1999-02-17 | カシオ計算機株式会社 | Liquid crystal display device and manufacturing method thereof |
| US5585388A (en) * | 1995-04-07 | 1996-12-17 | Sibia Neurosciences, Inc. | Substituted pyridines useful as modulators of acetylcholine receptors |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1047927A (en) * | 1964-03-09 | 1966-11-09 | Ici Ltd | Alkanolamine derivatives |
| US3261829A (en) * | 1964-08-12 | 1966-07-19 | Searle & Co | Spiro(steroidal-6,3'-1-pyrazolines) and process |
| US3679693A (en) * | 1970-09-15 | 1972-07-25 | Smith Kline French Lab | N-pyridylalkyl-{62 -alkoxy-{62 -trifluoromethyl-phenalkylamines |
| CH578532A5 (en) * | 1971-08-03 | 1976-08-13 | Cassella Farbwerke Mainkur Ag | |
| BE787057A (en) * | 1971-08-03 | 1973-02-01 | Cassella Farbwerke Mainkur Ag | DERIVATIVES OF PHENOXY-1 AMINO-3 PROPANOL-2 AND MEDICINES CONTAINING IT |
-
1972
- 1972-05-24 LU LU65414A patent/LU65414A1/xx unknown
-
1973
- 1973-05-09 DE DE2323354A patent/DE2323354A1/en active Pending
- 1973-05-14 NL NL7306691A patent/NL7306691A/xx not_active Application Discontinuation
- 1973-05-16 HU HUCA346A patent/HU165663B/hu unknown
- 1973-05-21 IE IE805/73A patent/IE37655B1/en unknown
- 1973-05-21 US US05/362,567 patent/US3940406A/en not_active Expired - Lifetime
- 1973-05-21 SU SU1923622A patent/SU489309A3/en active
- 1973-05-21 SU SU7301923620A patent/SU582755A3/en active
- 1973-05-21 SU SU1923621A patent/SU563120A3/en active
- 1973-05-22 BG BG23691A patent/BG20782A3/xx unknown
- 1973-05-22 JP JP48056386A patent/JPS4941380A/ja active Pending
- 1973-05-22 JP JP48056387A patent/JPS4948675A/ja active Pending
- 1973-05-22 DD DD170987A patent/DD106835A5/xx unknown
- 1973-05-22 BG BG24934A patent/BG22072A3/xx unknown
- 1973-05-22 BG BG24936A patent/BG21851A3/xx unknown
- 1973-05-22 IL IL42333A patent/IL42333A/en unknown
- 1973-05-23 ES ES415046A patent/ES415046A1/en not_active Expired
- 1973-05-23 AT AT450273A patent/AT326659B/en not_active IP Right Cessation
- 1973-05-23 AT AT450373A patent/AT326660B/en not_active IP Right Cessation
- 1973-05-23 ZA ZA733513A patent/ZA733513B/en unknown
- 1973-05-23 ES ES415045A patent/ES415045A1/en not_active Expired
- 1973-05-23 AR AR248190A patent/AR199905A1/en active
- 1973-05-23 AR AR248187A patent/AR199903A1/en active
- 1973-05-23 CH CH737673A patent/CH581621A5/xx not_active IP Right Cessation
- 1973-05-23 AR AR248189A patent/AR199904A1/en active
- 1973-05-23 CH CH737573A patent/CH581620A5/xx not_active IP Right Cessation
- 1973-05-23 JP JP48056904A patent/JPS4948678A/ja active Pending
- 1973-05-23 PL PL1973162780A patent/PL91588B1/pl unknown
- 1973-05-23 CS CS7300003715A patent/CS183702B2/en unknown
- 1973-05-23 CH CH737773A patent/CH581622A5/xx not_active IP Right Cessation
- 1973-05-23 SE SE7307242A patent/SE399425B/en unknown
- 1973-05-23 ES ES415047A patent/ES415047A1/en not_active Expired
- 1973-05-23 CS CS7300003713A patent/CS183701B2/en unknown
- 1973-05-23 RO RO7374886A patent/RO64607A/en unknown
- 1973-05-23 AT AT450073A patent/AT326657B/en not_active IP Right Cessation
- 1973-05-23 AT AT450173A patent/AT326658B/en not_active IP Right Cessation
- 1973-05-23 PH PH14648A patent/PH9827A/en unknown
- 1973-05-23 GB GB2458273A patent/GB1409959A/en not_active Expired
- 1973-05-23 CH CH737873A patent/CH596180A5/xx not_active IP Right Cessation
- 1973-05-23 CA CA172,038A patent/CA1015357A/en not_active Expired
- 1973-05-23 JP JP48056903A patent/JPS4948677A/ja active Pending
- 1973-05-23 SU SU1922038A patent/SU493958A3/en active
- 1973-05-23 CS CS7300003712A patent/CS183692B2/en unknown
- 1973-05-23 CS CS7300003714A patent/CS181241B2/en unknown
- 1973-05-23 RO RO7300077378A patent/RO66268A/en unknown
- 1973-05-23 ES ES415044A patent/ES415044A1/en not_active Expired
- 1973-05-24 BE BE131502A patent/BE800005A/en unknown
- 1973-05-24 FR FR7318866A patent/FR2185411B1/fr not_active Expired
-
1974
- 1974-03-08 PH PH15602*UA patent/PH9369A/en unknown
- 1974-03-08 PH PH15601*A patent/PH9508A/en unknown
- 1974-05-23 AR AR248188A patent/AR200869A1/en active
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