BRPI1008760A2 - ensaios homogêneos de fase de solução - Google Patents
ensaios homogêneos de fase de soluçãoInfo
- Publication number
- BRPI1008760A2 BRPI1008760A2 BRPI1008760A BRPI1008760A BRPI1008760A2 BR PI1008760 A2 BRPI1008760 A2 BR PI1008760A2 BR PI1008760 A BRPI1008760 A BR PI1008760A BR PI1008760 A BRPI1008760 A BR PI1008760A BR PI1008760 A2 BRPI1008760 A2 BR PI1008760A2
- Authority
- BR
- Brazil
- Prior art keywords
- homogeneous solution
- solution phase
- phase tests
- tests
- homogeneous
- Prior art date
Links
- 239000012456 homogeneous solution Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B15/00—Acridine dyes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/76—Chemiluminescence; Bioluminescence
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
- C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/76—Chemiluminescence; Bioluminescence
- G01N21/763—Bioluminescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plasma & Fusion (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15647309P | 2009-02-27 | 2009-02-27 | |
| US30031810P | 2010-02-01 | 2010-02-01 | |
| PCT/US2010/025657 WO2010099486A1 (en) | 2009-02-27 | 2010-02-26 | Solution phase homogeneous assays |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BRPI1008760A2 true BRPI1008760A2 (pt) | 2017-05-30 |
| BRPI1008760B1 BRPI1008760B1 (pt) | 2019-12-10 |
Family
ID=42102357
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI1008760 BRPI1008760B1 (pt) | 2009-02-27 | 2010-02-26 | método de ensaio e kit para um analito em uma amostra e sistema para realizar o método de ensaio |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US9029092B2 (pt) |
| EP (1) | EP2401392B1 (pt) |
| JP (2) | JP5844643B2 (pt) |
| KR (1) | KR101851797B1 (pt) |
| CN (1) | CN102333886B (pt) |
| AU (1) | AU2010217756B2 (pt) |
| BR (1) | BRPI1008760B1 (pt) |
| CA (1) | CA2753598C (pt) |
| ES (1) | ES2622977T3 (pt) |
| HU (1) | HUE031737T2 (pt) |
| MX (1) | MX2011009019A (pt) |
| PL (1) | PL2401392T3 (pt) |
| WO (1) | WO2010099486A1 (pt) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010099486A1 (en) | 2009-02-27 | 2010-09-02 | Beckman Coulter, Inc. | Solution phase homogeneous assays |
| MX2011009020A (es) * | 2009-02-27 | 2011-09-29 | Beckman Coulter Inc | Ensayo sin separacion con inhibidores de señal selectiva. |
| JP2013532275A (ja) * | 2010-05-14 | 2013-08-15 | ベックマン コールター， インコーポレイテッド | 高感度のホモジニアス化学発光アッセイ方法 |
| KR101975178B1 (ko) | 2011-11-21 | 2019-05-07 | 아박시스, 인크. | 측방 유동 및 관련된 면역검정에서의 신호 증폭 |
| CN102590190A (zh) * | 2012-01-31 | 2012-07-18 | 桂林理工大学 | Fe2+-H2O2-亚甲基蓝化学发光体系测定绿原酸的方法 |
| FR3019473B1 (fr) * | 2014-04-04 | 2016-05-06 | Prestodiag | Methode d'analyse microbiologique d'un echantillon dans un conteneur unique |
| FR3019654B1 (fr) | 2014-04-04 | 2020-10-30 | Bio Rad Innovations | Controles pour la mise en oeuvre de procedes d'analyse multiplexe |
| FR3019899B1 (fr) | 2014-04-09 | 2017-12-22 | Bio-Rad Innovations | Utilisation d'un colorant pour ameliorer la detection du signal dans un procede d'analyse |
| WO2015183931A1 (en) * | 2014-05-28 | 2015-12-03 | Li-Cor, Inc. | Stabilized chemiluminescent system |
| TWI691716B (zh) | 2014-08-13 | 2020-04-21 | 美商艾巴希斯公司 | 電漿特異性結合搭配物檢定中之信號放大 |
| KR102665867B1 (ko) * | 2015-04-06 | 2024-05-10 | 메소 스케일 테크놀러지즈, 엘엘시 | 소모성 진탕 장치를 포함하는, 전기화학발광을 이용하여 검정법을 수행하기 위한 고처리율 시스템 |
| CN104991076B (zh) * | 2015-07-06 | 2017-01-25 | 同昕生物技术（北京）有限公司 | 一种侧向层析系统及其应用 |
| CN117434261A (zh) | 2015-08-04 | 2024-01-23 | 硕腾服务有限责任公司 | 基于溶液的等离子体特异性结合配偶体测定中的信号放大 |
| JP6651794B2 (ja) * | 2015-11-05 | 2020-02-19 | 富士レビオ株式会社 | 心筋トロポニンｉ測定試薬及び方法 |
| CN110892250A (zh) | 2017-01-30 | 2020-03-17 | 爱贝斯股份有限公司 | 基于溶液的等离子体振子特异性结合配偶体测定和金属纳米结构 |
| CN107817347A (zh) * | 2017-09-25 | 2018-03-20 | 南京航思生物科技有限公司 | 一种均相发光法检测动物降钙素原的试剂盒 |
| CN108508198A (zh) * | 2018-06-21 | 2018-09-07 | 上海彧成生物科技有限公司 | 一种稳定的辣根过氧化物酶底物的配方 |
| WO2020012391A1 (en) | 2018-07-13 | 2020-01-16 | 3M Innovative Properties Company | Assay |
| WO2020012390A1 (en) | 2018-07-13 | 2020-01-16 | 3M Innovative Properties Company | Specific binding chemiluminescent assay |
| JP7153493B2 (ja) * | 2018-07-27 | 2022-10-14 | シスメックス株式会社 | 生体粒子の測定方法、非特異シグナルの検出方法、生体粒子測定方法及び生体粒子を検出するための試薬キット |
| WO2020028619A1 (en) | 2018-08-01 | 2020-02-06 | Beckman Coulter, Inc. | Sparc based microorganism detection method |
| CN109085338B (zh) * | 2018-09-13 | 2021-07-13 | 武汉伊莱瑞特生物科技股份有限公司 | Ecl底物液及其制备方法和应用 |
| CN109725162A (zh) * | 2018-12-21 | 2019-05-07 | 广州市进德生物科技有限公司 | 一种完全均相测定胰岛素的检测试剂盒及其方法 |
| CN109655626A (zh) * | 2018-12-21 | 2019-04-19 | 广州市进德生物科技有限公司 | 一种完全均相测定胰高血糖素的检测试剂盒及其方法 |
| CN109613232A (zh) * | 2018-12-21 | 2019-04-12 | 广州市进德生物科技有限公司 | 一种完全均相测定脂联素的检测试剂盒及检测方法 |
| CN109655615A (zh) * | 2018-12-21 | 2019-04-19 | 广州市进德生物科技有限公司 | 一种完全均相测定脂蛋白相关磷脂酶a2的检测试剂盒及其方法 |
| CN109613243A (zh) * | 2018-12-21 | 2019-04-12 | 广州市进德生物科技有限公司 | 一种完全均相测定髓过氧化物酶的检测试剂盒及检测方法 |
| CN109613260A (zh) * | 2018-12-21 | 2019-04-12 | 广州市进德生物科技有限公司 | 一种完全均相测定尿微量白蛋白的检测试剂盒及其检测方法 |
| CN109613281A (zh) * | 2018-12-21 | 2019-04-12 | 广州市进德生物科技有限公司 | 一种完全均相测定氧化低密度脂蛋白的检测试剂盒及其方法 |
| CN110031635A (zh) * | 2019-05-16 | 2019-07-19 | 杭州普鲁米生物科技有限公司 | 闪光型均相化学发光技术检测心肌肌钙蛋白i/t的方法 |
| CN109975558A (zh) * | 2019-05-16 | 2019-07-05 | 杭州普鲁米生物科技有限公司 | 闪光型均相化学发光技术检测人绒毛膜促性腺激素β的方法 |
| CN116859057A (zh) * | 2019-12-31 | 2023-10-10 | 科美诊断技术(苏州)有限公司 | 一种肌红蛋白的均相检测试剂盒及其应用 |
| CN116449001A (zh) * | 2019-12-31 | 2023-07-18 | 科美博阳诊断技术(上海)有限公司 | 一种cTnI检测试剂盒及其应用 |
| IT202000001327A1 (it) * | 2020-01-23 | 2021-07-23 | Cyanagen S R L | Substrati chemiluminescenti per perossidasi con una lunga durata di conservazione |
| CN112684163B (zh) * | 2021-01-29 | 2022-08-09 | 安邦（厦门）生物科技有限公司 | 一种吖啶类化合物标记原料工作液及制备方法 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4837395A (en) | 1985-05-10 | 1989-06-06 | Syntex (U.S.A.) Inc. | Single step heterogeneous assay |
| DE3537877A1 (de) | 1985-10-24 | 1987-04-30 | Geiger Reinhard | Luciferin-derivate und immunoassays unter einsatz derartiger luciferin-derivate |
| US4943525A (en) | 1987-11-02 | 1990-07-24 | Bioventures, Inc. | Simultaneous immunoassay for the determination of antigens and antibodies |
| DE68928412T2 (de) | 1988-07-08 | 1998-05-20 | Jbl Scient Inc | Herstellung und verwendung von fluoreszierenden benzothiazolderivaten |
| DE68911633T2 (de) * | 1988-09-30 | 1994-04-07 | Fujirebio Kk | Verfahren zur Bestimmung von Peroxidase-Aktivität unter Verwendung von Chemilumineszenz. |
| DK0422252T3 (da) | 1989-04-28 | 1995-09-11 | Toray Industries | Metode til påvisning af et stof under anvendelse af kemiluminescens |
| US5324835A (en) | 1990-03-30 | 1994-06-28 | Biosensor Laboratories Co., Ltd. | Pyridazinoquinoxalinones for use as chemiluminescent agents |
| IE66038B1 (en) * | 1990-06-12 | 1995-12-13 | British Tech Group | Antioxidant assay |
| CA2056142A1 (en) | 1990-11-27 | 1992-05-28 | Hirotomo Masuya | Pyridopyridazine compounds and their use |
| US6251581B1 (en) * | 1991-05-22 | 2001-06-26 | Dade Behring Marburg Gmbh | Assay method utilizing induced luminescence |
| US5512451A (en) | 1993-04-01 | 1996-04-30 | British Technology Group Limited | Enhancement of chemiluminescent reactions |
| US5491072A (en) | 1993-05-17 | 1996-02-13 | Lumigen, Inc. | N-alkylacridan carboxyl derivatives useful for chemiluminescent detection |
| US5593845A (en) | 1993-05-17 | 1997-01-14 | Lumigen, Inc. | Aryl N-alkylacridancarboxylate derivatives useful for chemiluminescent detection |
| US5523212A (en) * | 1993-05-17 | 1996-06-04 | Lumigen, Inc. | Aryl N-alkylacridanthiocarboxylate derivatives useful for chemiluminescent detection |
| JPH07311197A (ja) | 1994-05-18 | 1995-11-28 | Tosoh Corp | 化学発光増強法 |
| EP0915851B1 (en) | 1996-07-16 | 2002-03-20 | De Staat Der Nederlanden Vertegenwoordigd Door De Minister Van Welzijn, Volksgezondheid En Cultuur | Dibenzodihydropyridinecarboxylic esters and their use in chemiluminescent assay methods |
| US6140051A (en) | 1997-07-21 | 2000-10-31 | Promega Biosciences, Inc. | Fluorescent dibenzazole derivatives and methods related thereto |
| DE69823845T2 (de) | 1997-09-12 | 2005-04-28 | Lumigen, Inc., Southfield | Neue verbindungen zur erzeugung von chemilumineszenz mit hilfe einer peroxidase |
| US5922558A (en) * | 1997-09-12 | 1999-07-13 | Lumigen, Inc. | Methods and compositions for generating chemiluminescence with a peroxidase |
| US6162610A (en) | 1998-09-11 | 2000-12-19 | Tropix, Inc. | Xanthan-ester and acridan substrates for horseradish peroxidase |
| US20020110842A1 (en) | 2001-02-15 | 2002-08-15 | Seymon Bystryak | Photochemical amplified immunoassay |
| US6764819B2 (en) * | 2002-07-16 | 2004-07-20 | Emp Biotech Gmbh | Method for chemiluminescent detection |
| US7682839B2 (en) * | 2005-03-14 | 2010-03-23 | Lumigen, Inc. | Methods using novel chemiluminescent labels |
| EP2778234B1 (en) | 2005-05-31 | 2017-09-27 | Promega Corporation | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions |
| WO2007058654A1 (en) | 2005-11-17 | 2007-05-24 | Siemens Healthcare Diagnostics Inc. | Reduction of non-specific binding in assays |
| US7732153B2 (en) | 2006-05-09 | 2010-06-08 | Beckman Coulter, Inc. | Nonseparation assay methods |
| US7799534B2 (en) * | 2006-05-09 | 2010-09-21 | Beckman Coulter, Inc. | Nonseparation assay methods |
| WO2010099486A1 (en) | 2009-02-27 | 2010-09-02 | Beckman Coulter, Inc. | Solution phase homogeneous assays |
| JP2013532275A (ja) * | 2010-05-14 | 2013-08-15 | ベックマン コールター， インコーポレイテッド | 高感度のホモジニアス化学発光アッセイ方法 |
-
2010
- 2010-02-26 WO PCT/US2010/025657 patent/WO2010099486A1/en active Application Filing
- 2010-02-26 BR BRPI1008760 patent/BRPI1008760B1/pt not_active IP Right Cessation
- 2010-02-26 JP JP2011552201A patent/JP5844643B2/ja active Active
- 2010-02-26 MX MX2011009019A patent/MX2011009019A/es active IP Right Grant
- 2010-02-26 KR KR1020117022505A patent/KR101851797B1/ko active IP Right Grant
- 2010-02-26 HU HUE10707170A patent/HUE031737T2/en unknown
- 2010-02-26 EP EP10707170.6A patent/EP2401392B1/en active Active
- 2010-02-26 AU AU2010217756A patent/AU2010217756B2/en not_active Ceased
- 2010-02-26 CN CN201080009871.XA patent/CN102333886B/zh active Active
- 2010-02-26 ES ES10707170.6T patent/ES2622977T3/es active Active
- 2010-02-26 CA CA2753598A patent/CA2753598C/en active Active
- 2010-02-26 PL PL10707170T patent/PL2401392T3/pl unknown
- 2010-02-26 US US12/714,346 patent/US9029092B2/en active Active
-
2015
- 2015-04-02 US US14/677,524 patent/US10036708B2/en not_active Ceased
- 2015-07-02 JP JP2015133808A patent/JP6037522B2/ja active Active
-
2020
- 2020-07-31 US US16/945,391 patent/USRE49466E1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US10036708B2 (en) | 2018-07-31 |
| US20100267071A1 (en) | 2010-10-21 |
| EP2401392A1 (en) | 2012-01-04 |
| KR20110134426A (ko) | 2011-12-14 |
| JP2012519285A (ja) | 2012-08-23 |
| JP6037522B2 (ja) | 2016-12-07 |
| CN102333886A (zh) | 2012-01-25 |
| CN102333886B (zh) | 2018-01-19 |
| CA2753598A1 (en) | 2010-09-02 |
| WO2010099486A1 (en) | 2010-09-02 |
| JP5844643B2 (ja) | 2016-01-20 |
| US9029092B2 (en) | 2015-05-12 |
| MX2011009019A (es) | 2011-09-29 |
| ES2622977T3 (es) | 2017-07-10 |
| AU2010217756A1 (en) | 2011-09-15 |
| EP2401392B1 (en) | 2017-01-25 |
| PL2401392T3 (pl) | 2017-08-31 |
| HUE031737T2 (en) | 2017-07-28 |
| JP2015172604A (ja) | 2015-10-01 |
| US20150212005A1 (en) | 2015-07-30 |
| CA2753598C (en) | 2018-07-10 |
| BRPI1008760B1 (pt) | 2019-12-10 |
| AU2010217756B2 (en) | 2016-07-14 |
| USRE49466E1 (en) | 2023-03-21 |
| KR101851797B1 (ko) | 2018-04-24 |
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| B15I | Others concerning applications: loss of priority | ||
| B12F | Other appeals [chapter 12.6 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
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| B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
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| B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
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