MX2011009020A - Ensayo sin separacion con inhibidores de señal selectiva. - Google Patents

Ensayo sin separacion con inhibidores de señal selectiva.

Info

Publication number
MX2011009020A
MX2011009020A MX2011009020A MX2011009020A MX2011009020A MX 2011009020 A MX2011009020 A MX 2011009020A MX 2011009020 A MX2011009020 A MX 2011009020A MX 2011009020 A MX2011009020 A MX 2011009020A MX 2011009020 A MX2011009020 A MX 2011009020A
Authority
MX
Mexico
Prior art keywords
specific binding
binding member
labeled
sample
reaction mixture
Prior art date
Application number
MX2011009020A
Other languages
English (en)
Inventor
Hashem Akhavan-Tafti
Renuka De Silva
Terri Mclernon
James Mendoza
Michael Salvati
Nir Shapir
Wenhua Xie
Original Assignee
Beckman Coulter Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beckman Coulter Inc filed Critical Beckman Coulter Inc
Publication of MX2011009020A publication Critical patent/MX2011009020A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B15/00—Acridine dyes
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B21/00—Thiazine dyes
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B57/00—Other synthetic dyes of known constitution
    • C09B57/02—Coumarine dyes
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B67/00—Influencing the physical, e.g. the dyeing or printing properties of dyestuffs without chemical reactions, e.g. by treating with solvents grinding or grinding assistants, coating of pigments or dyes; Process features in the making of dyestuff preparations; Dyestuff preparations of a special physical nature, e.g. tablets, films
    • C09B67/0033—Blends of pigments; Mixtured crystals; Solid solutions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Se describen métodos, reactivos, equipos y sistemas para determinar un material para análisis en una muestra, en donde el método comprende formar una mezcla de reacción en una solución acuosa, agregando un miembro de enlace específico inmovilizado etiquetado-quimioluminiscente, un miembro de enlace específico etiquetado con activador, un agente de inhibición de señal selectivo, y una muestra, en donde el miembro de enlace específico inmovilizado etiquetado10 quimioluminiscente y el miembro de enlace específico etiquetado con activador enlazan al material para análisis presente en la muestra para formar un complejo de enlace, y agregar a la mezcla de reacción una solución de activación para liberar una señal quimioluminiscente detectable correlacionada con la cantidad del complejo de enlace enlazado con material para análisis presente en la mezcla de reacción.
MX2011009020A 2009-02-27 2010-02-26 Ensayo sin separacion con inhibidores de señal selectiva. MX2011009020A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15647109P 2009-02-27 2009-02-27
US30031410P 2010-02-01 2010-02-01
PCT/US2010/025645 WO2010099479A1 (en) 2009-02-27 2010-02-26 Non separation assays with selective signal inhibitors

Publications (1)

Publication Number Publication Date
MX2011009020A true MX2011009020A (es) 2011-09-29

Family

ID=42194711

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011009020A MX2011009020A (es) 2009-02-27 2010-02-26 Ensayo sin separacion con inhibidores de señal selectiva.

Country Status (9)

Country Link
US (1) US20100273189A1 (es)
EP (1) EP2401393A1 (es)
JP (1) JP2012519284A (es)
KR (1) KR20110137324A (es)
CN (1) CN102333885A (es)
AU (1) AU2010217839A1 (es)
CA (1) CA2753596A1 (es)
MX (1) MX2011009020A (es)
WO (1) WO2010099479A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20130091644A (ko) * 2010-05-14 2013-08-19 베크만 컬터, 인코포레이티드 감도가 증가된 균질 화학발광 검정 방법
US9636423B2 (en) * 2010-06-02 2017-05-02 The General Hospital Corporation Optical sensor conjugates for detecting reactive oxygen and/or reactive nitrogen species in vivo
KR101369392B1 (ko) * 2013-01-03 2014-03-06 한국과학기술연구원 결합형 나노입자의 결합효율 분석방법
CN104237520B (zh) * 2014-09-30 2016-09-28 博奥赛斯（天津）生物科技有限公司 一种丙型肝炎病毒抗原抗体联合检测试剂盒及其制备方法
WO2018133038A1 (zh) * 2017-01-20 2018-07-26 深圳市新产业生物医学工程股份有限公司 标记复合物及其制备方法、试剂盒、应用和检测系统
CN112400113B (zh) * 2018-07-13 2022-04-15 3M创新有限公司 特异性结合化学发光测定法
EP3821029A1 (en) * 2018-07-13 2021-05-19 3M Innovative Properties Company Assay
IT202000001327A1 (it) * 2020-01-23 2021-07-23 Cyanagen S R L Substrati chemiluminescenti per perossidasi con una lunga durata di conservazione
CN111717909B (zh) * 2020-05-28 2022-07-01 济南大学 一种富勒烯-四氧化三锡检测降钙素原的夹心型光电化学传感器的制备方法
CN116804630B (zh) * 2023-08-03 2024-03-05 中拓生物有限公司 一种血清同型半胱氨酸测定试剂盒

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KR960002875B1 (ko) 1989-04-28 1996-02-27 도오레 가부시기가이샤 옥사졸유도체 및 이것을 이용한 고감도 발광분석방법
US5324835A (en) 1990-03-30 1994-06-28 Biosensor Laboratories Co., Ltd. Pyridazinoquinoxalinones for use as chemiluminescent agents
DK0533764T3 (da) * 1990-06-12 1997-09-29 British Tech Group Antioxidantassay
CA2056142A1 (en) 1990-11-27 1992-05-28 Hirotomo Masuya Pyridopyridazine compounds and their use
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Also Published As

Publication number Publication date
KR20110137324A (ko) 2011-12-22
EP2401393A1 (en) 2012-01-04
CA2753596A1 (en) 2010-09-02
WO2010099479A1 (en) 2010-09-02
US20100273189A1 (en) 2010-10-28
CN102333885A (zh) 2012-01-25
AU2010217839A1 (en) 2011-09-15
JP2012519284A (ja) 2012-08-23

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