MX346499B - Dispositivos, metodos y kits de inmunocromatografia. - Google Patents

Dispositivos, metodos y kits de inmunocromatografia.

Info

Publication number
MX346499B
MX346499B MX2013003161A MX2013003161A MX346499B MX 346499 B MX346499 B MX 346499B MX 2013003161 A MX2013003161 A MX 2013003161A MX 2013003161 A MX2013003161 A MX 2013003161A MX 346499 B MX346499 B MX 346499B
Authority
MX
Mexico
Prior art keywords
kits
methods
analyte
membrane
capture antibody
Prior art date
Application number
MX2013003161A
Other languages
English (en)
Other versions
MX2013003161A (es
Inventor
Marco Grebe
Original Assignee
Grifols Therapeutics Inc *
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Grifols Therapeutics Inc * filed Critical Grifols Therapeutics Inc *
Publication of MX2013003161A publication Critical patent/MX2013003161A/es
Publication of MX346499B publication Critical patent/MX346499B/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/38—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against protease inhibitors of peptide structure
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G01N33/54388—Immunochromatographic test strips based on lateral flow
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/81—Protease inhibitors
    • G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • G01N2333/811—Serine protease (E.C. 3.4.21) inhibitors
    • G01N2333/8121—Serpins
    • G01N2333/8125—Alpha-1-antitrypsin

Abstract

La presente invención se refiere a un dispositivo para inmunoensayo que comprende: una membrana que tiene una zona de captura de proteína Z-AAT definida por un anticuerpo de captura inmovilizado en la misma: una zona de aplicación de muestra y una trayectoria de flujo desde la zona de aplicación de muestra a la zona de captura de proteína Z-AAT; y una estructura conjugada situada en la trayectoria de flujo, cuya estructura conjugada comprende un reactivo de detección específico para la proteína Z-AAT, siendo el reactivo de detección móvil o movilizable, en el que el anticuerpo de captura es: el anticuerpo monoclonal LG96 producido por células de hibridoma depositadas con n° de Acceso DSM ACC3092; o el anticuerpo monoclonal MG97 producido por células de hibridoma depositadas con n° de Acceso DMS ACC3093; y en el que el reactivo de detección es un anticuerpo detector seleccionado entre: anticuerpo monoclonal LG96 producido por células de hibridoma depositadas con n| de Acceso DSM ACC3092; o bien anticuerpo monoclonal MG97 producido por células de hibridoma depositadas con n° de Acceso DSM ACC3093.
MX2013003161A 2010-09-24 2011-09-23 Dispositivos, metodos y kits de inmunocromatografia. MX346499B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US38621410P 2010-09-24 2010-09-24
US201161482867P 2011-05-05 2011-05-05
PCT/IB2011/002232 WO2012038820A2 (en) 2010-09-24 2011-09-23 Immunochromatography devices, methods and kits

Publications (2)

Publication Number Publication Date
MX2013003161A MX2013003161A (es) 2013-04-24
MX346499B true MX346499B (es) 2017-03-22

Family

ID=45874209

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013003161A MX346499B (es) 2010-09-24 2011-09-23 Dispositivos, metodos y kits de inmunocromatografia.

Country Status (22)

Country Link
US (2) US9121857B2 (es)
EP (1) EP2619581B1 (es)
JP (1) JP5852657B2 (es)
KR (1) KR101753447B1 (es)
CN (1) CN103140758B (es)
AU (1) AU2011306651B2 (es)
BR (1) BR112013008602B1 (es)
CA (1) CA2811706C (es)
CL (1) CL2013000813A1 (es)
ES (1) ES2552649T3 (es)
HK (1) HK1183514A1 (es)
HU (1) HUE025584T2 (es)
IL (1) IL225268A (es)
MX (1) MX346499B (es)
MY (1) MY172290A (es)
NZ (1) NZ609824A (es)
PL (1) PL2619581T3 (es)
PT (1) PT2619581E (es)
RU (1) RU2568875C2 (es)
SG (1) SG189060A1 (es)
WO (1) WO2012038820A2 (es)
ZA (1) ZA201302099B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014159312A2 (en) * 2013-03-14 2014-10-02 University Of Florida Research Foundation, Incorporated A novel single chain antibody reduced mutant alpha-1 antitrypsin aggregation and toxicity
WO2014176556A1 (en) * 2013-04-26 2014-10-30 Express Diagnostics International, Inc. Portable testing system for detecting selected drugs or compounds in non-controlled environments
US20180306785A1 (en) * 2015-10-26 2018-10-25 Wellbeing Technologies Corp. Lateral flow assay devices and methods
US10983119B2 (en) 2016-01-25 2021-04-20 General Electric Company Device for rapid diagnostic tests to detect antigens with improved sensitivity
US20170212112A1 (en) * 2016-01-25 2017-07-27 General Electric Company Integration of sample separation with rapid diagnostic tests for improved sensitivity
EP3411716A1 (en) * 2016-02-03 2018-12-12 Nordic Bioscience A/S Combined biomarker measurement of fibrosis
CN111684280A (zh) * 2017-12-05 2020-09-18 贝克顿·迪金森公司 用于检测高浓度分析物的侧向流动测定和方法
CN108931653A (zh) * 2018-08-31 2018-12-04 广州华澳生物科技有限公司 一种α1- 抗胰蛋白酶免疫层析检测试剂卡及其制备方法
US11884672B2 (en) 2019-05-14 2024-01-30 Vertex Pharmaceuticals Incorporated Modulators of alpha-1 antitrypsin
EP3816626A1 (en) * 2019-10-30 2021-05-05 Feral GmbH Lateral flow test arrangement suitable for detection of an analyte in saliva
WO2022104353A1 (en) 2020-11-12 2022-05-19 Vertex Pharmaceuticals Incorporated Methods of monitoring alpha-1 antitrypsin (aat) deficiency by measuring polymerised aat
FR3119023A1 (fr) * 2021-01-21 2022-07-22 Ng Biotech Système pour l’analyse rapide d’un échantillon de sang capillaire provenant d’un sujet, destiné à la détection de la présence d’au moins un analyte dans ledit échantillon de sang capillaire
CN113075396A (zh) * 2021-03-25 2021-07-06 江苏硕世生物科技股份有限公司 一种检测辅助装置
CN113791209B (zh) * 2021-08-12 2024-01-26 重庆工商大学 一种无钩状效应的免疫层析试纸条及制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8904007D0 (sv) * 1989-11-28 1989-11-28 Ferring Ab Monoklona antikroppar och diagnostiseringsmetod
JPH11201969A (ja) * 1998-01-14 1999-07-30 Wakamoto Pharmaceut Co Ltd 簡易遊離ヘモグロビン測定方法および測定用キット
GB9919226D0 (en) * 1999-08-13 1999-10-20 Medical Res Council Allele detection
US7605004B2 (en) * 2001-07-18 2009-10-20 Relia Diagnostic Systems Llc Test strip for a lateral flow assay for a sample containing whole cells
US20030092090A1 (en) * 2001-11-14 2003-05-15 Kiamars Hajizadeh Rapid prion-detection device, system, and test kit
US20060246513A1 (en) 2005-05-02 2006-11-02 Bohannon Robert C Method and device to detect the presence of analytes in a sample
CN201203618Y (zh) * 2008-05-29 2009-03-04 重庆工学院 一种新城疫病毒免疫胶体金测试卡
US9110058B2 (en) 2008-06-30 2015-08-18 Sekisui Medical Co., Ltd. Porous solid phase for binding assay, and binding assay method using the same
DE102009007616A1 (de) 2009-02-05 2010-08-12 Gaudlitz Gmbh Testvorrichtung für Flüssigkeiten des menschlichen oder tierischen Körpers

Also Published As

Publication number Publication date
CA2811706A1 (en) 2012-03-29
BR112013008602B1 (pt) 2020-11-17
WO2012038820A2 (en) 2012-03-29
RU2013118695A (ru) 2014-10-27
IL225268A (en) 2016-06-30
AU2011306651A1 (en) 2013-04-04
HK1183514A1 (en) 2013-12-27
MY172290A (en) 2019-11-20
AU2011306651B2 (en) 2015-06-11
MX2013003161A (es) 2013-04-24
CN103140758A (zh) 2013-06-05
KR101753447B1 (ko) 2017-07-03
US9921229B2 (en) 2018-03-20
RU2568875C2 (ru) 2015-11-20
WO2012038820A3 (en) 2012-08-02
EP2619581B1 (en) 2015-09-30
NZ609824A (en) 2014-10-31
ZA201302099B (en) 2017-08-30
ES2552649T3 (es) 2015-12-01
JP5852657B2 (ja) 2016-02-03
PL2619581T3 (pl) 2016-02-29
EP2619581A4 (en) 2014-04-09
SG189060A1 (en) 2013-05-31
CA2811706C (en) 2017-03-28
JP2013539029A (ja) 2013-10-17
US20150323526A1 (en) 2015-11-12
HUE025584T2 (en) 2016-04-28
BR112013008602A2 (pt) 2016-07-12
US20130183698A1 (en) 2013-07-18
CL2013000813A1 (es) 2014-04-04
IL225268A0 (en) 2013-06-27
US9121857B2 (en) 2015-09-01
CN103140758B (zh) 2015-03-11
KR20130115262A (ko) 2013-10-21
PT2619581E (pt) 2015-12-02
EP2619581A2 (en) 2013-07-31

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