BRPI0718247B1 - Composto usado como inibidor do transportador de monoamina vesicular 2, composição farmacêutica compreendendo o dito composto e uso da dita composição farmacêutica no tratamento de transtornos hipercinéticos - Google Patents
Composto usado como inibidor do transportador de monoamina vesicular 2, composição farmacêutica compreendendo o dito composto e uso da dita composição farmacêutica no tratamento de transtornos hipercinéticos Download PDFInfo
- Publication number
- BRPI0718247B1 BRPI0718247B1 BRPI0718247-3A BRPI0718247A BRPI0718247B1 BR PI0718247 B1 BRPI0718247 B1 BR PI0718247B1 BR PI0718247 A BRPI0718247 A BR PI0718247A BR PI0718247 B1 BRPI0718247 B1 BR PI0718247B1
- Authority
- BR
- Brazil
- Prior art keywords
- compound
- compounds
- isobutyl
- dimethoxy
- isoquinolin
- Prior art date
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| ES2652289T3 (es) | 2008-09-18 | 2018-02-01 | Auspex Pharmaceuticals, Inc. | Derivados deuterados de benzoquinolina como inhibidores del transportador de monoamina vesicular 2 |
| CN104744456A (zh) * | 2010-06-01 | 2015-07-01 | 奥斯拜客斯制药有限公司 | Vmat2的苯并喹啉酮抑制剂 |
| WO2012000308A1 (zh) * | 2010-06-29 | 2012-01-05 | 中国药科大学 | 丁苯那嗪的拆分方法 |
| US8351329B2 (en) * | 2010-09-14 | 2013-01-08 | Cisco Technology, Inc. | Universal load-balancing tunnel encapsulation |
| CN102285984B (zh) * | 2010-11-25 | 2012-10-10 | 江苏威凯尔医药科技有限公司 | (2R,3R,11bR)-二氢丁苯那嗪及相关化合物的制备方法 |
| WO2012081031A1 (en) | 2010-12-15 | 2012-06-21 | Enaltec Labs Pvt. Ltd. | Process for preparing tetrabenazine |
| US9550780B2 (en) | 2012-09-18 | 2017-01-24 | Auspex Pharmaceuticals, Inc. | Formulations pharmacokinetics of deuterated benzoquinoline inhibitors of vesicular monoamine transporter 2 |
| CN116768882A (zh) | 2012-09-18 | 2023-09-19 | 奥斯拜客斯制药有限公司 | 化合物、及其药物组合物及治疗方法 |
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| JP2010509366A (ja) | 2010-03-25 |
| BRPI0718247A2 (pt) | 2014-01-07 |
| CN101553487B (zh) | 2012-06-13 |
| EA018378B1 (ru) | 2013-07-30 |
| PL2081929T3 (pl) | 2013-06-28 |
| CA2668689A1 (en) | 2008-05-15 |
| JP5290185B2 (ja) | 2013-09-18 |
| EP2081929B1 (en) | 2013-01-09 |
| EA200970461A1 (ru) | 2009-12-30 |
| EP2081929A1 (en) | 2009-07-29 |
| IL198250A0 (en) | 2009-12-24 |
| KR101500766B9 (ko) | 2024-09-25 |
| ES2402220T8 (es) | 2021-12-23 |
| KR20090079257A (ko) | 2009-07-21 |
| KR101500766B1 (ko) | 2015-03-16 |
| US8357697B2 (en) | 2013-01-22 |
| US20080167337A1 (en) | 2008-07-10 |
| US20120077839A1 (en) | 2012-03-29 |
| PT2081929E (pt) | 2013-04-15 |
| CA2668689C (en) | 2015-12-29 |
| MX2009004910A (es) | 2009-07-24 |
| US8039627B2 (en) | 2011-10-18 |
| AU2007317242B2 (en) | 2013-08-01 |
| DK2081929T3 (da) | 2013-04-15 |
| CN101553487A (zh) | 2009-10-07 |
| ES2402220T3 (es) | 2013-04-29 |
| AU2007317242A1 (en) | 2008-05-15 |
| WO2008058261A1 (en) | 2008-05-15 |
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