BRPI0709936A2 - bi-aril aminas - Google Patents
bi-aril aminas Download PDFInfo
- Publication number
- BRPI0709936A2 BRPI0709936A2 BRPI0709936-3A BRPI0709936A BRPI0709936A2 BR PI0709936 A2 BRPI0709936 A2 BR PI0709936A2 BR PI0709936 A BRPI0709936 A BR PI0709936A BR PI0709936 A2 BRPI0709936 A2 BR PI0709936A2
- Authority
- BR
- Brazil
- Prior art keywords
- chloro
- formula
- disorders
- pyridin
- phenyl
- Prior art date
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- 150000004982 aromatic amines Chemical class 0.000 title 1
- 238000000034 method Methods 0.000 claims abstract description 45
- 150000003839 salts Chemical class 0.000 claims abstract description 16
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 29
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- 125000000217 alkyl group Chemical group 0.000 claims description 23
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Classifications
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- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
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- C07—ORGANIC CHEMISTRY
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Landscapes
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0606774.8 | 2006-04-03 | ||
| GBGB0606774.8A GB0606774D0 (en) | 2006-04-03 | 2006-04-03 | Organic compounds |
| PCT/EP2007/053155 WO2007113276A1 (en) | 2006-04-03 | 2007-04-02 | Novel bi-aryl amines |
Publications (1)
| Publication Number | Publication Date |
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| BRPI0709936A2 true BRPI0709936A2 (pt) | 2011-08-02 |
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| Application Number | Title | Priority Date | Filing Date |
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| BRPI0709936-3A BRPI0709936A2 (pt) | 2006-04-03 | 2007-04-02 | bi-aril aminas |
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| Country | Link |
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| US (1) | US20090286827A1 (enExample) |
| EP (1) | EP2004624A1 (enExample) |
| JP (1) | JP2009532429A (enExample) |
| KR (1) | KR20090005354A (enExample) |
| CN (1) | CN101460478A (enExample) |
| AU (1) | AU2007233669A1 (enExample) |
| BR (1) | BRPI0709936A2 (enExample) |
| CA (1) | CA2646088A1 (enExample) |
| GB (1) | GB0606774D0 (enExample) |
| MX (1) | MX2008012818A (enExample) |
| RU (1) | RU2008143180A (enExample) |
| WO (1) | WO2007113276A1 (enExample) |
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| GB0420722D0 (en) | 2004-09-17 | 2004-10-20 | Addex Pharmaceuticals Sa | Novel allosteric modulators |
| WO2007013830A1 (en) | 2005-07-26 | 2007-02-01 | Portela & Ca. S.A. | Nitrocatechol derivatives as comt inhibitors |
| AR059898A1 (es) | 2006-03-15 | 2008-05-07 | Janssen Pharmaceutica Nv | Derivados de 3-ciano-piridona 1,4-disustituida y su uso como moduladores alostericos de los receptores mglur2 |
| EP1845097A1 (en) | 2006-04-10 | 2007-10-17 | Portela & Ca., S.A. | Oxadiazole derivatives as COMT inhibitors |
| DK2481410T3 (en) | 2007-01-31 | 2016-10-24 | Bial - Portela & Ca S A | Nitrocatecholderivater as COMT inhibitors administered in a specific dosage regimen |
| TW200845978A (en) | 2007-03-07 | 2008-12-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives |
| TW200900065A (en) | 2007-03-07 | 2009-01-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives |
| TW200922566A (en) | 2007-09-14 | 2009-06-01 | Ortho Mcneil Janssen Pharm | 1,3 disubstituted 4-(aryl-X-phenyl)-1H-pyridin-2-ones |
| BRPI0816970A2 (pt) | 2007-09-14 | 2015-03-24 | Ortho Mcneil Janssen Pharm | 1,3-dissubstituídas-4-fenil-1h-piridin-2-onas |
| EA017648B1 (ru) | 2007-09-14 | 2013-02-28 | Орто-Макнейл-Янссен Фармасьютикалз, Инк. | 1',3'-двузамещенные-4-фенил-3,4,5,6-тетрагидро-2н,1'н-[1,4']бипириди-нил-2'-оны |
| CA2704436C (en) | 2007-11-14 | 2016-01-05 | Ortho-Mcneil-Janssen Pharmaceuticals, Inc. | Imidazo[1,2-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors |
| BRPI0908731A2 (pt) | 2008-03-17 | 2017-05-16 | Bial - Portela & C A S A | formas cristalinas de 5-[3-(2,5-dicloro-4,6-dimetil-1-óxi-piridina-3-il)[1,2,4]oxadiazol-5-il]-3-nitrobenzeno-1,2-diol |
| JP5547194B2 (ja) | 2008-09-02 | 2014-07-09 | ジャンセン ファーマシューティカルズ， インコーポレイテッド． | 代謝型グルタミン酸受容体の調節因子としての３−アザビシクロ［３．１．０］ヘキシル誘導体 |
| MY154000A (en) | 2008-09-22 | 2015-04-30 | Cayman Chem Co | Multiheteroaryl compounds as inhibitors of h-pgds and their use for treating prostaglandin d2 mediated diseases |
| CA2739263A1 (en) * | 2008-10-03 | 2010-04-08 | Lexicon Pharmaceuticals, Inc. | Tryptophan hydroxylase inhibitors and methods of their use |
| WO2010043396A1 (en) | 2008-10-16 | 2010-04-22 | Ortho-Mcneil-Janssen Pharmaceuticals, Inc. | Indole and benzomorpholine derivatives as modulators of metabotropic glutamate receptors |
| JP5690277B2 (ja) | 2008-11-28 | 2015-03-25 | ジャンセン ファーマシューティカルズ， インコーポレイテッド． | 代謝型グルタミン酸受容体の調節因子としてのインドールおよびベンゾオキサジン誘導体 |
| PA8854101A1 (es) | 2008-12-18 | 2010-07-27 | Ortho Mcneil Janssen Pharm | Derivados de imidazol bicíclicos sustituidos como moduladores de gamma secretasa |
| CN102325765B (zh) | 2009-02-06 | 2014-12-24 | 杨森制药公司 | 作为γ-分泌酶调节剂的取代的双环杂环化合物 |
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| US10562897B2 (en) | 2014-01-16 | 2020-02-18 | Janssen Pharmaceutica Nv | Substituted 3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-diones as gamma secretase modulators |
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|---|---|---|---|---|
| EP0164204A1 (en) * | 1984-05-12 | 1985-12-11 | FISONS plc | Novel pharmaceutically useful pyrimidines |
| GB8412184D0 (en) * | 1984-05-12 | 1984-06-20 | Fisons Plc | Biologically active nitrogen heterocycles |
| AU2001278206A1 (en) * | 2000-08-08 | 2002-02-18 | Ortho-Mcneil Pharmaceutical, Inc. | Neuroprotective 2-pyridinamine compositions and related methods |
| BR0208010A (pt) * | 2001-03-12 | 2004-12-21 | Avanir Pharmaceuticals | Composto de benzimidazol para modulação de ige e inibição de proliferação celular |
| EP1658291B1 (en) * | 2003-08-25 | 2013-10-02 | Dogwood Pharmaceuticals, Inc. | Substituted 8-heteroaryl xanthines |
| EP1715867A4 (en) * | 2004-02-12 | 2009-04-15 | Merck & Co Inc | BIPYRIDYLAMIDE AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTOR-5 |
| WO2005113548A1 (en) * | 2004-05-20 | 2005-12-01 | Sugen, Inc. | Thiophene heteroaryl amines |
| WO2008128968A1 (en) * | 2007-04-19 | 2008-10-30 | Novartis Ag | Nicotinic acid derivatives as modulators of metabotropic glutamate receptor-5 |
-
2006
- 2006-04-03 GB GBGB0606774.8A patent/GB0606774D0/en not_active Ceased
-
2007
- 2007-04-02 JP JP2009503560A patent/JP2009532429A/ja active Pending
- 2007-04-02 KR KR1020087026788A patent/KR20090005354A/ko not_active Withdrawn
- 2007-04-02 US US12/296,034 patent/US20090286827A1/en not_active Abandoned
- 2007-04-02 RU RU2008143180/04A patent/RU2008143180A/ru not_active Application Discontinuation
- 2007-04-02 BR BRPI0709936-3A patent/BRPI0709936A2/pt not_active Application Discontinuation
- 2007-04-02 EP EP07727627A patent/EP2004624A1/en not_active Withdrawn
- 2007-04-02 WO PCT/EP2007/053155 patent/WO2007113276A1/en not_active Ceased
- 2007-04-02 MX MX2008012818A patent/MX2008012818A/es not_active Application Discontinuation
- 2007-04-02 AU AU2007233669A patent/AU2007233669A1/en not_active Abandoned
- 2007-04-02 CA CA002646088A patent/CA2646088A1/en not_active Abandoned
- 2007-04-02 CN CNA2007800204897A patent/CN101460478A/zh active Pending
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| CA2646088A1 (en) | 2007-10-11 |
| EP2004624A1 (en) | 2008-12-24 |
| AU2007233669A1 (en) | 2007-10-11 |
| RU2008143180A (ru) | 2010-05-10 |
| MX2008012818A (es) | 2008-10-15 |
| KR20090005354A (ko) | 2009-01-13 |
| CN101460478A (zh) | 2009-06-17 |
| JP2009532429A (ja) | 2009-09-10 |
| US20090286827A1 (en) | 2009-11-19 |
| WO2007113276A1 (en) | 2007-10-11 |
| GB0606774D0 (en) | 2006-05-10 |
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