BRPI0617219B8 - método automatizado para a preparação de uma composição radiofarmacêutica estéril marcada com 123i, e, cassete estéril - Google Patents

método automatizado para a preparação de uma composição radiofarmacêutica estéril marcada com 123i, e, cassete estéril

Info

Publication number
BRPI0617219B8
BRPI0617219B8 BRPI0617219A BRPI0617219A BRPI0617219B8 BR PI0617219 B8 BRPI0617219 B8 BR PI0617219B8 BR PI0617219 A BRPI0617219 A BR PI0617219A BR PI0617219 A BRPI0617219 A BR PI0617219A BR PI0617219 B8 BRPI0617219 B8 BR PI0617219B8
Authority
BR
Brazil
Prior art keywords
sterile
preparing
automated method
cassette
radiopharmaceutical composition
Prior art date
Application number
BRPI0617219A
Other languages
English (en)
Inventor
Higley Brian
Anthony Powell Nigel
Paul Pettitt Roger
Original Assignee
Ge Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare Ltd filed Critical Ge Healthcare Ltd
Publication of BRPI0617219A2 publication Critical patent/BRPI0617219A2/pt
Publication of BRPI0617219B1 publication Critical patent/BRPI0617219B1/pt
Publication of BRPI0617219B8 publication Critical patent/BRPI0617219B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0446—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K51/0448—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil tropane or nortropane groups, e.g. cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Optics & Photonics (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Input Circuits Of Receivers And Coupling Of Receivers And Audio Equipment (AREA)
  • Magnetic Heads (AREA)
  • Gyroscopes (AREA)
  • Radiation-Therapy Devices (AREA)

Abstract

método automatizado para a preparação de uma composição radiofarmacêutica estéril marcada com 123i cassete estéril, e, usos de aparelho de sintetizador automatizado, e do cassete. a presente invenção proporciona um método automatizado para a preparação de composições radiofarmacêuticas marcadas com ^ 123i, juntamente com cassetes descartáveis para uso no método. o uso de uma aparelhagem de sintetizador automatizado na preparação de radiofármacos marcados com 123i também é descrito. também é descrito o uso de cassetes da presente invenção na preparação de radiofármacos marcados com 123i.
BRPI0617219A 2005-10-10 2006-10-09 método automatizado para a preparação de uma composição radiofarmacêutica estéril marcada com 123i, e, cassete estéril BRPI0617219B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0520529.9A GB0520529D0 (en) 2005-10-10 2005-10-10 Automated radiolabelling method
GB0520529.9 2005-10-10
PCT/GB2006/003758 WO2007042791A2 (en) 2005-10-10 2006-10-09 Automated radiolabelling method

Publications (3)

Publication Number Publication Date
BRPI0617219A2 BRPI0617219A2 (pt) 2011-07-19
BRPI0617219B1 BRPI0617219B1 (pt) 2019-03-26
BRPI0617219B8 true BRPI0617219B8 (pt) 2021-07-27

Family

ID=35430073

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0617219A BRPI0617219B8 (pt) 2005-10-10 2006-10-09 método automatizado para a preparação de uma composição radiofarmacêutica estéril marcada com 123i, e, cassete estéril

Country Status (12)

Country Link
US (1) US9585976B2 (pt)
EP (1) EP1933885B1 (pt)
JP (1) JP2009511461A (pt)
CN (1) CN101282746B (pt)
AT (1) ATE439869T1 (pt)
BR (1) BRPI0617219B8 (pt)
CA (1) CA2624794C (pt)
DE (1) DE602006008639D1 (pt)
ES (1) ES2331856T3 (pt)
GB (1) GB0520529D0 (pt)
RU (1) RU2459632C2 (pt)
WO (1) WO2007042791A2 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2704104C (en) * 2007-10-31 2016-02-02 Alseres Pharmaceuticals, Inc. Labeled iodinated tropane formulation
GB0901483D0 (en) * 2009-01-29 2009-03-11 Ge Healthcare Ltd Radioiodination method
US8333952B2 (en) * 2009-09-23 2012-12-18 Abt Molecular Imaging, Inc. Dose synthesis module for biomarker generator system
US10109385B2 (en) 2009-09-23 2018-10-23 Abt Molecular Imaging, Inc. Dose synthesis card for use with automated biomarker production system
US9291606B2 (en) * 2010-08-20 2016-03-22 General Electric Company Quality control devices and methods for radiopharmaceuticals
US9101895B2 (en) 2011-04-15 2015-08-11 General Electric Company System for mixing and dispersing microbubble pharmaceuticals
GB201209082D0 (en) * 2012-05-24 2012-07-04 Ge Healthcare Ltd Purification method
KR101550399B1 (ko) 2013-10-10 2015-09-08 한국원자력의학원 방사면역접합체 또는 방사표지펩티드 제조용 링커 화합물 및 그 제조방법
US20160022846A1 (en) * 2014-07-22 2016-01-28 Ge Healthcare Limited Iodine radiolabelling method
CN107530455A (zh) * 2015-02-10 2018-01-02 Abt分子成像公司 与自动化生物标记物生产系统联用的剂量合成卡
US20180209921A1 (en) * 2017-01-20 2018-07-26 Mallinckrodt Nuclear Medicine Llc Systems and methods for assaying an eluate of a radionuclide generator

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2607861C2 (de) 1976-02-24 1985-04-25 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren und Reagenziensatz zur Herstellung von durch 123↓J↓, 131↓J↓ oder 132↓J↓ markierter ortho-Jodhippursäure
JPH07318695A (ja) * 1994-05-24 1995-12-08 Takeda Chem Ind Ltd 放射性核種を含む化合物の自動合成装置および自動合成方法
JPH07318694A (ja) * 1994-05-24 1995-12-08 Seitai Kinou Kenkyusho:Kk １１ｃ標識メチル化合物の注射製剤の自動合成装置および自動合成方法
JPH0826975A (ja) * 1994-07-08 1996-01-30 Seitai Kinou Kenkyusho:Kk ▲１１ｃ▼標識カルボキシル化合物の注射用製剤の自動合成装置および自動合成方法
US7521531B2 (en) 1996-08-28 2009-04-21 Immunomedics, Inc. Methods for the purification of stable radioiodine conjugates
WO1998018499A1 (en) 1996-10-29 1998-05-07 Guilford Pharmaceuticals Inc. Process for the preparation of radiopharmaceuticals
EP1216715A1 (fr) * 2000-12-22 2002-06-26 Ion Beam Applications S.A. Dispositif de synthèse de produits radiopharmaceutiques
KR100520291B1 (ko) * 2003-02-22 2005-10-13 한국원자력연구소 아이백이십삼 엠아이비지 자동 합성장치 및 그를 이용한아이백이십삼 엠아이비지의 합성방법
JP4264510B2 (ja) * 2003-09-30 2009-05-20 独立行政法人放射線医学総合研究所 自動合成装置
GB0410448D0 (en) * 2004-05-11 2004-06-16 Hammersmith Imanet Ltd Purification methods
US7229603B2 (en) * 2004-06-17 2007-06-12 Anazaohealth Corporation Stablilized and lyophilized radiopharmaceutical agents
DE102005028897A1 (de) * 2005-06-17 2006-12-28 Eckert & Ziegler Eurotope Gmbh Anordnung und Verfahren zur Verarbeitung von chemischen Stoffen, Computerprogramm zur Steuerung einer solchen Anordnung sowie ein entsprechendes computerlesbares Speichermedium
US7586102B2 (en) * 2006-08-14 2009-09-08 Board Of Regents The University Of Texas System Automated system for formulating radiopharmaceuticals

Also Published As

Publication number Publication date
ATE439869T1 (de) 2009-09-15
CN101282746B (zh) 2011-11-09
ES2331856T3 (es) 2010-01-18
BRPI0617219B1 (pt) 2019-03-26
GB0520529D0 (en) 2005-11-16
CA2624794C (en) 2014-04-08
RU2008112557A (ru) 2009-11-20
WO2007042791A3 (en) 2007-09-07
EP1933885B1 (en) 2009-08-19
BRPI0617219A2 (pt) 2011-07-19
EP1933885A2 (en) 2008-06-25
CA2624794A1 (en) 2007-04-19
RU2459632C2 (ru) 2012-08-27
DE602006008639D1 (de) 2009-10-01
JP2009511461A (ja) 2009-03-19
US20080226552A1 (en) 2008-09-18
CN101282746A (zh) 2008-10-08
WO2007042791A2 (en) 2007-04-19
US9585976B2 (en) 2017-03-07

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 26/03/2019, OBSERVADAS AS CONDICOES LEGAIS. (CO) 10 (DEZ) ANOS CONTADOS A PARTIR DE 26/03/2019, OBSERVADAS AS CONDICOES LEGAIS

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 09/10/2006, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO