BRPI0518198B8 - método ex vivo para tratar uma composição de células hemácias para inativar um patógeno, se presente, bem como composição e kit - Google Patents
método ex vivo para tratar uma composição de células hemácias para inativar um patógeno, se presente, bem como composição e kitInfo
- Publication number
- BRPI0518198B8 BRPI0518198B8 BRPI0518198A BRPI0518198A BRPI0518198B8 BR PI0518198 B8 BRPI0518198 B8 BR PI0518198B8 BR PI0518198 A BRPI0518198 A BR PI0518198A BR PI0518198 A BRPI0518198 A BR PI0518198A BR PI0518198 B8 BRPI0518198 B8 BR PI0518198B8
- Authority
- BR
- Brazil
- Prior art keywords
- composition
- pathogen
- red cell
- red
- cell
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
- A61L2/16—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using chemical substances
- A61L2/18—Liquid substances
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/124—Disinfecting agents, e.g. antimicrobials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2103/00—Materials or objects being the target of disinfection or sterilisation
- A61L2103/05—Living organisms or biological materials
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Environmental Sciences (AREA)
- Zoology (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Diabetes (AREA)
- Tropical Medicine & Parasitology (AREA)
- Hematology (AREA)
- Virology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62317704P | 2004-10-29 | 2004-10-29 | |
| US60/623,177 | 2004-10-29 | ||
| PCT/US2005/039392 WO2006050328A1 (en) | 2004-10-29 | 2005-10-31 | Improved quenching methods for red blood cell inactivation process |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI0518198A BRPI0518198A (pt) | 2008-11-04 |
| BRPI0518198B1 BRPI0518198B1 (pt) | 2018-11-21 |
| BRPI0518198B8 true BRPI0518198B8 (pt) | 2021-06-22 |
Family
ID=35789172
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0518198A BRPI0518198B8 (pt) | 2004-10-29 | 2005-10-31 | método ex vivo para tratar uma composição de células hemácias para inativar um patógeno, se presente, bem como composição e kit |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7655392B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1838355B1 (cg-RX-API-DMAC7.html) |
| JP (3) | JP5346468B2 (cg-RX-API-DMAC7.html) |
| CN (2) | CN101094692A (cg-RX-API-DMAC7.html) |
| AU (2) | AU2005302256B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0518198B8 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2585621C (cg-RX-API-DMAC7.html) |
| DK (1) | DK1838355T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2429088T3 (cg-RX-API-DMAC7.html) |
| PL (1) | PL1838355T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT1838355E (cg-RX-API-DMAC7.html) |
| WO (1) | WO2006050328A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69826521T2 (de) * | 1998-01-06 | 2005-09-29 | Cerus Corp., Concord | Verfahren zum quenchen von pathogen-inaktivatoren in biologischen materialien |
| JP5346468B2 (ja) | 2004-10-29 | 2013-11-20 | シーラス コーポレイション | 赤血球不活性化プロセスのための改善されたクエンチング方法 |
| KR101896430B1 (ko) * | 2008-04-09 | 2018-09-10 | 세루스 코포레이션 | 적혈구 병원체 불활성화를 위한 개선된 퀀칭 방법 |
| US11284616B2 (en) | 2010-05-05 | 2022-03-29 | Hemanext Inc. | Irradiation of red blood cells and anaerobic storage |
| US9199016B2 (en) | 2009-10-12 | 2015-12-01 | New Health Sciences, Inc. | System for extended storage of red blood cells and methods of use |
| US12089589B2 (en) | 2009-10-12 | 2024-09-17 | Hemanext Inc. | Irradiation of red blood cells and anaerobic storage |
| US7989593B1 (en) | 2010-05-27 | 2011-08-02 | Bing Lou Wong | Method for the preparation of a high-temperature stable oxygen-carrier-containing pharmaceutical composition and the use thereof |
| US7932356B1 (en) | 2010-06-23 | 2011-04-26 | Bing Lou Wong | Method for the preparation of a heat stable oxygen carrier-containing pharmaceutical composition |
| US8048856B1 (en) | 2010-06-23 | 2011-11-01 | Billion King, Ltd. | Treatment methods using a heat stable oxygen carrier-containing pharmaceutical composition |
| US8084581B1 (en) | 2011-04-29 | 2011-12-27 | Bing Lou Wong | Method for removing unmodified hemoglobin from cross-linked hemoglobin solutions including polymeric hemoglobin with a high temperature short time heat treatment apparatus |
| US20130052232A1 (en) | 2011-08-31 | 2013-02-28 | Bing Lou Wong | Method for the preparation of a heat stable oxygen carrier-containing composition facilating beta-beta cross-linking |
| US20160081328A1 (en) * | 2013-05-10 | 2016-03-24 | President And Fellows Of Harvard College | Solutions for Red Blood Cells |
| EA201790265A1 (ru) | 2014-07-23 | 2017-07-31 | Сирус Корпорейшн | Способы получения тромбоцит-содержащих продуктов |
| KR20250033333A (ko) | 2015-03-10 | 2025-03-07 | 헤마넥스트 인코포레이티드 | 산소 감소 1회용 키트, 장치 및 이의 사용 방법 |
| BR122022005103B1 (pt) | 2015-04-23 | 2023-03-14 | Hemanext Inc | Dispositivo de armazenamento de sangue para armazenar sangue depletado de oxigênio e método para armazenar sangue depletado de oxigênio |
| PT3297641T (pt) | 2015-05-18 | 2025-10-09 | Hemanext Inc | Métodos de armazenamento de sangue total e respetivas composições |
| CN122182613A (zh) | 2015-06-26 | 2026-06-12 | 塞鲁斯公司 | 冷沉淀物组合物及其制备方法 |
| US10799533B2 (en) | 2015-10-23 | 2020-10-13 | Cerus Corporation | Plasma compositions and methods of use thereof |
| CN109195632A (zh) * | 2016-05-27 | 2019-01-11 | 新健康科学股份有限公司 | 厌氧血液储存和病原体失活方法 |
| AU2017382449B2 (en) * | 2016-12-23 | 2024-10-24 | Cerus Corporation | Systems and methods for testing and screening using compound bound substrates |
| US20190321407A1 (en) * | 2016-12-31 | 2019-10-24 | Cerus Corporation | Compositions and methods for preparation of red blood cells |
| EP4606379A3 (en) | 2017-03-03 | 2025-11-19 | Cerus Corporation | Kits and methods for preparing pathogen-inactivated platelet compositions |
| AU2018338097B2 (en) | 2017-09-20 | 2023-07-13 | Cerus Corporation | Compositions and methods for pathogen inactivation of platelets |
| JP7311518B2 (ja) | 2017-12-29 | 2023-07-19 | シーラス コーポレイション | 生物学的流体を処理するためのシステムおよび方法 |
| US20210227827A1 (en) * | 2018-07-27 | 2021-07-29 | Zata Pharmaceuticals, Inc. | Method for pathogens, microorganisms, and parasites inactivation |
| CA3113655A1 (en) * | 2018-09-20 | 2020-03-26 | Cerus Corporation | Methods and kits for preparing pathogen-inactivated whole blood |
| WO2020263745A1 (en) | 2019-06-22 | 2020-12-30 | Cerus Corporation | Systems and methods for implementing treatment of biological fluids |
| CN114173842B (zh) | 2019-06-22 | 2026-07-14 | 塞鲁斯公司 | 生物流体处理系统 |
| JP7645203B2 (ja) | 2019-06-28 | 2025-03-13 | シーラス コーポレイション | 生物学的流体処理デバイスを実装するためのシステム及び方法 |
| EP4240757A2 (en) | 2020-11-09 | 2023-09-13 | Takeda Pharmaceutical Company Limited | Purification of fviii from plasma using silicon oxide adsorption |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2402665A (en) | 1942-11-12 | 1946-06-25 | Du Pont | Chemical process |
| IT1093275B (it) | 1978-01-26 | 1985-07-19 | Snam Progetti | Composizione adatta alla purificazione del sangue e suoi impieghi |
| US4337269A (en) | 1979-07-23 | 1982-06-29 | Sutton Laboratories, Inc. | Preservative compositions |
| US4748120A (en) | 1983-05-02 | 1988-05-31 | Diamond Scientific Co. | Photochemical decontamination treatment of whole blood or blood components |
| US4727027A (en) | 1983-05-02 | 1988-02-23 | Diamond Scientific Co. | Photochemical decontamination treatment of whole blood or blood components |
| US5281579A (en) | 1984-03-23 | 1994-01-25 | Baxter International Inc. | Purified virus-free hemoglobin solutions and method for making same |
| US4971760A (en) | 1986-03-10 | 1990-11-20 | University Of Southern California | Novel method for disinfecting red blood cells, blood platelets, blood plasma, and optical corneas and sclerae |
| US4944920A (en) | 1986-08-01 | 1990-07-31 | University Of Southern California | Novel method to treat blood |
| US4920143A (en) | 1987-04-23 | 1990-04-24 | University Of British Columbia | Hydro-monobenzoporphyrin wavelength-specific cytotoxic agents |
| US5094960A (en) | 1988-10-07 | 1992-03-10 | New York Blood Center, Inc. | Removal of process chemicals from labile biological mixtures by hydrophobic interaction chromatography |
| US5055485A (en) | 1988-12-02 | 1991-10-08 | New York Blood Center, Inc. | Inactivation of viruses in cell- and protein-containing compositions using aryl diol epoxides |
| US5587490A (en) | 1990-04-16 | 1996-12-24 | Credit Managers Association Of California | Method of inactivation of viral and bacterial blood contaminants |
| US5418130A (en) | 1990-04-16 | 1995-05-23 | Cryopharm Corporation | Method of inactivation of viral and bacterial blood contaminants |
| US5658722A (en) | 1990-05-15 | 1997-08-19 | New York Blood Center, Inc. | Process for the sterilization of biological compositions using UVA1 irradiation |
| US5232844A (en) | 1990-05-15 | 1993-08-03 | New York Blood Center | Photodynamic inactivation of viruses in cell-containing compositions |
| US5120649A (en) | 1990-05-15 | 1992-06-09 | New York Blood Center, Inc. | Photodynamic inactivation of viruses in blood cell-containing compositions |
| US5753258A (en) | 1990-10-19 | 1998-05-19 | University Of Florida | Artificial viral envelopes |
| GB9218581D0 (en) | 1992-09-02 | 1992-10-14 | Pall Corp | Removal of unwanted fluids from processed blood products |
| CA2165065A1 (en) | 1993-06-23 | 1995-01-05 | Henrietta Margolis-Nunno | System for viral inactivation of blood |
| US5591350A (en) | 1994-04-15 | 1997-01-07 | Pall Corporation | Iodine disinfection method using a gaseous iodine treated porous medium |
| SE9402472L (sv) | 1994-07-13 | 1996-01-14 | Forskarpatent I Linkoeping Ab | Modifierade ytor |
| US5522385A (en) | 1994-09-27 | 1996-06-04 | Aradigm Corporation | Dynamic particle size control for aerosolized drug delivery |
| US5660731A (en) | 1994-11-08 | 1997-08-26 | Pall Corporation | Filter for separating photoactive agent |
| US5691132A (en) | 1994-11-14 | 1997-11-25 | Cerus Corporation | Method for inactivating pathogens in red cell compositions using quinacrine mustard |
| US5637451A (en) | 1995-03-29 | 1997-06-10 | New York Blood Center, Inc. | Photodynamic treatment of red blood cells with phthalocyanines and red light at higher light fluence rates is protective of red blood cells |
| US6177441B1 (en) | 1995-06-05 | 2001-01-23 | Cerus Corporation | Treating red blood cell solutions with anti-viral agents |
| EP0840781B1 (en) | 1995-06-07 | 2009-12-09 | Cerus Corporation | Methods and devices for the removal of psoralens from blood products |
| US6544727B1 (en) | 1995-06-07 | 2003-04-08 | Cerus Corporation | Methods and devices for the removal of psoralens from blood products |
| AU703108B2 (en) | 1995-06-07 | 1999-03-18 | Baxter International Inc. | Method of inactivation of viral and bacterial blood contaminants |
| US20020192632A1 (en) | 1995-06-07 | 2002-12-19 | Hei Derek J. | Method and devices for the removal of psoralens from blood products |
| EP0773716A4 (en) | 1995-06-07 | 1999-08-04 | Cerus Corp | TREATMENT OF RED BLOOD CELL SOLUTIONS WITH ANTIVRAL ACTIVE SUBSTANCES |
| AU7717396A (en) | 1995-06-29 | 1997-02-05 | Hemasure, Inc. | Inactivation of pathogens using hydroxymethylamines |
| US6136586A (en) | 1995-08-29 | 2000-10-24 | Vi Technologies, Inc. | Methods for the selective modification of viral nucleic acids |
| US6114108A (en) | 1995-08-29 | 2000-09-05 | V.I. Technologies, Inc. | Methods and compositions for the selective modification of viral nucleic acids |
| CA2236873A1 (en) | 1995-11-06 | 1997-05-15 | New York Blood Center, Inc. | Viral inactivation treatment of red blood cells using phthalocyanines and red light |
| WO1997018844A1 (en) | 1995-11-21 | 1997-05-29 | Pall Corporation | Inactivation method and system in biological fluids |
| US6514987B1 (en) | 1997-01-06 | 2003-02-04 | Cerus Corporation | Frangible compounds for pathogen inactivation |
| ATE243198T1 (de) | 1997-01-06 | 2003-07-15 | Cerus Corp | Verbindungen mit leicht spaltbaren bindungen zur inaktivierung von pathogenen |
| US6093725A (en) | 1997-01-06 | 2000-07-25 | Cerus Corporation | Frangible compounds for pathogen inactivation |
| US20010018179A1 (en) | 1998-01-06 | 2001-08-30 | Derek J. Hei | Batch devices for the reduction of compounds from biological compositions containing cells and methods of use |
| US20010009756A1 (en) | 1998-01-06 | 2001-07-26 | Derek Hei | Flow devices for the reduction of compounds from biological compositions and methods of use |
| US6093564A (en) | 1997-10-03 | 2000-07-25 | V.I. Technologies, Inc. | Methods and compositions for the selective modification of nucleic acids |
| DE69826521T2 (de) * | 1998-01-06 | 2005-09-29 | Cerus Corp., Concord | Verfahren zum quenchen von pathogen-inaktivatoren in biologischen materialien |
| US6277337B1 (en) * | 1998-07-21 | 2001-08-21 | Gambro, Inc. | Method and apparatus for inactivation of biological contaminants using photosensitizers |
| US6150109A (en) | 1999-01-25 | 2000-11-21 | V. I. TECHNOLOGIES, Inc. | Lipophilic quenching of viral inactivating agents |
| CN1436083A (zh) * | 2000-05-31 | 2003-08-13 | 塞鲁斯公司 | 制备病原体灭活的低免疫原性红细胞溶液 |
| CN100417325C (zh) * | 2000-11-04 | 2008-09-10 | 王祥文 | 卫生灭菌消毒剂 |
| US20030113704A1 (en) * | 2000-12-21 | 2003-06-19 | Cerus Corporation | Methods for inactivation of pathogens in biological materials |
| CN1186099C (zh) * | 2001-12-13 | 2005-01-26 | 孙岩军 | 麻醉机呼吸回路清洗消毒的方法及其操作步骤 |
| JP5346468B2 (ja) | 2004-10-29 | 2013-11-20 | シーラス コーポレイション | 赤血球不活性化プロセスのための改善されたクエンチング方法 |
-
2005
- 2005-10-31 JP JP2007539281A patent/JP5346468B2/ja not_active Expired - Lifetime
- 2005-10-31 CN CNA2005800453138A patent/CN101094692A/zh active Pending
- 2005-10-31 BR BRPI0518198A patent/BRPI0518198B8/pt not_active IP Right Cessation
- 2005-10-31 AU AU2005302256A patent/AU2005302256B2/en not_active Ceased
- 2005-10-31 CA CA2585621A patent/CA2585621C/en not_active Expired - Lifetime
- 2005-10-31 PL PL05821102T patent/PL1838355T3/pl unknown
- 2005-10-31 PT PT58211020T patent/PT1838355E/pt unknown
- 2005-10-31 ES ES05821102T patent/ES2429088T3/es not_active Expired - Lifetime
- 2005-10-31 US US11/264,195 patent/US7655392B2/en active Active
- 2005-10-31 WO PCT/US2005/039392 patent/WO2006050328A1/en not_active Ceased
- 2005-10-31 DK DK05821102.0T patent/DK1838355T3/da active
- 2005-10-31 EP EP05821102.0A patent/EP1838355B1/en not_active Expired - Lifetime
- 2005-10-31 CN CN201410112134.2A patent/CN103961731B/zh not_active Expired - Lifetime
-
2011
- 2011-04-06 AU AU2011201554A patent/AU2011201554B2/en not_active Ceased
-
2012
- 2012-03-07 JP JP2012050837A patent/JP5718840B2/ja not_active Expired - Lifetime
-
2013
- 2013-09-27 JP JP2013200906A patent/JP2013256537A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| HK1109594A1 (en) | 2008-06-13 |
| DK1838355T3 (da) | 2013-10-28 |
| CA2585621C (en) | 2015-12-15 |
| US20060115466A1 (en) | 2006-06-01 |
| AU2005302256A1 (en) | 2006-05-11 |
| EP1838355A1 (en) | 2007-10-03 |
| CN101094692A (zh) | 2007-12-26 |
| AU2011201554B2 (en) | 2012-04-26 |
| JP2013256537A (ja) | 2013-12-26 |
| AU2005302256B2 (en) | 2011-01-20 |
| JP5718840B2 (ja) | 2015-05-13 |
| CA2585621A1 (en) | 2006-05-11 |
| JP2012107068A (ja) | 2012-06-07 |
| CN103961731B (zh) | 2017-01-18 |
| JP2008518952A (ja) | 2008-06-05 |
| WO2006050328A1 (en) | 2006-05-11 |
| US7655392B2 (en) | 2010-02-02 |
| CN103961731A (zh) | 2014-08-06 |
| PT1838355E (pt) | 2013-11-07 |
| ES2429088T3 (es) | 2013-11-13 |
| BRPI0518198A (pt) | 2008-11-04 |
| BRPI0518198B1 (pt) | 2018-11-21 |
| JP5346468B2 (ja) | 2013-11-20 |
| EP1838355B1 (en) | 2013-08-14 |
| PL1838355T3 (pl) | 2014-01-31 |
| AU2011201554A1 (en) | 2011-04-28 |
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