BRPI0512261A - antagonistas de receptor de hormÈnio liberador de gonadotropina - Google Patents
antagonistas de receptor de hormÈnio liberador de gonadotropinaInfo
- Publication number
- BRPI0512261A BRPI0512261A BRPI0512261-9A BRPI0512261A BRPI0512261A BR PI0512261 A BRPI0512261 A BR PI0512261A BR PI0512261 A BRPI0512261 A BR PI0512261A BR PI0512261 A BRPI0512261 A BR PI0512261A
- Authority
- BR
- Brazil
- Prior art keywords
- releasing hormone
- gonadotropin
- receptor antagonists
- hormone receptor
- antagonists
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/08—Radicals containing only hydrogen and carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Abstract
ANTAGONISTAS DE RECEPTOR DE HORMÈNIO LIBERADOR DE GONADOTROPINA. A presente invenção se refere aos antagonistas do receptor do Hormónio Liberador de Gonadotropina ("GnRH") (da mesma forma conhecido como Hormónio Liberador do Hormónio Leuteinizante).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US58064004P | 2004-06-17 | 2004-06-17 | |
PCT/US2005/021124 WO2006009734A1 (en) | 2004-06-17 | 2005-06-16 | Gonadotropin releasing hormone receptor antagonists |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0512261A true BRPI0512261A (pt) | 2008-02-26 |
Family
ID=35033296
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0512261-9A BRPI0512261A (pt) | 2004-06-17 | 2005-06-16 | antagonistas de receptor de hormÈnio liberador de gonadotropina |
Country Status (15)
Country | Link |
---|---|
US (1) | US7696210B2 (pt) |
EP (1) | EP1758895A1 (pt) |
JP (1) | JP2008503469A (pt) |
KR (1) | KR20070027584A (pt) |
CN (1) | CN101006078A (pt) |
AU (1) | AU2005264996A1 (pt) |
BR (1) | BRPI0512261A (pt) |
CA (1) | CA2570968A1 (pt) |
CR (1) | CR8799A (pt) |
EC (1) | ECSP067090A (pt) |
MX (1) | MXPA06014798A (pt) |
NO (1) | NO20070294L (pt) |
RU (1) | RU2007101544A (pt) |
WO (1) | WO2006009734A1 (pt) |
ZA (1) | ZA200610589B (pt) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
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US7696210B2 (en) | 2004-06-17 | 2010-04-13 | Wyeth | Gonadotropin releasing hormone receptor antagonists |
NZ552093A (en) * | 2004-06-17 | 2009-06-26 | Wyeth Corp | Processes for preparing gonadotropin releasing hormone receptor antagonists |
JP5209311B2 (ja) * | 2004-09-03 | 2013-06-12 | メルク セローノ ソシエテ アノニム | ピリジンメチレンアゾリジノン及びホスホイノシチド阻害剤としてのその使用 |
AU2005286648A1 (en) | 2004-09-20 | 2006-03-30 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors |
BRPI0515482A (pt) | 2004-09-20 | 2008-07-22 | Xenon Pharmaceuticals Inc | derivados heterocìclicos e seus usos como agentes terapêuticos |
JP2008520732A (ja) * | 2004-11-23 | 2008-06-19 | ワイス | ゴナドトロピン放出ホルモン受容体アンタゴニスト |
US7582634B2 (en) * | 2005-02-18 | 2009-09-01 | Wyeth | 7-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor |
US7534796B2 (en) * | 2005-02-18 | 2009-05-19 | Wyeth | Imidazo[4,5-b]pyridine antagonists of gonadotropin releasing hormone receptor |
US7538113B2 (en) * | 2005-02-18 | 2009-05-26 | Wyeth | 4-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor |
US20060189619A1 (en) * | 2005-02-24 | 2006-08-24 | Wyeth | 3-({4-[2-(4-Tert-butylphenyl)-1h-benzimidazol-4-yl]piperazin-1-yl}methyl)pyrido[2,3-b]]pyrazi ne compounds |
CN101133051A (zh) * | 2005-03-07 | 2008-02-27 | 惠氏公司 | 喹喔啉二氢卤酸盐二水合物及其合成方法 |
US7531542B2 (en) * | 2005-05-18 | 2009-05-12 | Wyeth | Benzooxazole and benzothiazole antagonists of gonadotropin releasing hormone receptor |
US7582636B2 (en) * | 2005-05-26 | 2009-09-01 | Wyeth | Piperazinylimidazopyridine and piperazinyltriazolopyridine antagonists of Gonadotropin Releasing Hormone receptor |
JP2009513563A (ja) | 2005-06-03 | 2009-04-02 | ゼノン・ファーマシューティカルズ・インコーポレイテッド | ヒトのステアロイル−CoAデサチュラーゼ阻害剤としてのアミノチアゾール誘導体 |
DE102006032589A1 (de) * | 2006-07-13 | 2008-01-17 | Bayer Healthcare Ag | Verfahren zur Herstellung von 5-Formylpyridin-2-carbonitril |
WO2008102501A1 (ja) * | 2007-02-20 | 2008-08-28 | E & F Co., Ltd. | ゴルフクラブヘッド及びそのゴルフクラブヘッドを製造する方法 |
JP5313883B2 (ja) | 2007-04-18 | 2013-10-09 | キッセイ薬品工業株式会社 | 含窒素縮合環誘導体、それを含有する医薬組成物及びその医薬用途 |
BRPI0811204A8 (pt) | 2007-05-10 | 2015-09-22 | Bristol Myers Squibb Co | Tetra-hidroibenzo-1,4-diazepinas substituídas por arila e heteroarila e uso das mesmas para bloquear a recaptação de norepinefrina, dopamina e serotonina |
MX2010001866A (es) * | 2007-08-23 | 2010-03-11 | Sanofi Aventis | Derivados de azoloarina, metodo para su produccion, productos farmaceuticos que contienen estos compuestos y su uso. |
DE102008030091B4 (de) * | 2008-06-25 | 2011-03-03 | Resprotect Gmbh | Uracilderivate und deren Verwendung |
DE102008039083A1 (de) | 2008-08-21 | 2010-02-25 | Bayer Schering Pharma Aktiengesellschaft | Substituierte 5-Aminopyrazole und ihre Verwendung |
KR101779137B1 (ko) | 2009-01-23 | 2017-09-18 | 다케다 야쿠힌 고교 가부시키가이샤 | 폴리(adp-리보스)폴리머라제(parp) 억제제 |
EP2414328B1 (en) * | 2009-04-02 | 2021-05-26 | Merck Serono S.A. | Dihydroorotate dehydrogenase inhibitors |
JP5715625B2 (ja) | 2009-07-30 | 2015-05-07 | 武田薬品工業株式会社 | ポリ(adp−リボース)ポリメラーゼ(parp)阻害剤 |
EP2516425B1 (en) | 2009-12-23 | 2015-09-02 | Jasco Pharmaceuticals LLC | Aminopyrimidine kinase inhibitors |
AR084706A1 (es) * | 2010-07-16 | 2013-06-05 | Piramal Life Sciences Ltd | Derivados sustituidos de imidazoquinolinas como inhibidores de quinasa y proceso para su preparacion |
WO2012145617A2 (en) | 2011-04-22 | 2012-10-26 | Jasco Pharmaceuticals, LLC | Aminopyrimidine kinase inhibitors |
CN104011046B (zh) | 2011-11-04 | 2017-05-03 | 嘉世高制药公司 | 氨基嘧啶激酶抑制剂 |
PL3023415T3 (pl) | 2012-10-02 | 2018-06-29 | Gilead Sciences, Inc. | Inhibitory demetylaz histonowych |
GB201321736D0 (en) * | 2013-12-09 | 2014-01-22 | Ucb Pharma Sa | Therapeutic agents |
CN104277042A (zh) * | 2014-10-15 | 2015-01-14 | 湖南华腾制药有限公司 | 一种咪唑并吡啶衍生物的制备方法 |
CN104628721A (zh) * | 2015-01-22 | 2015-05-20 | 湖南华腾制药有限公司 | 一种咪唑并[1,2-a]吡啶衍生物的制备方法 |
KR20240005756A (ko) * | 2021-04-23 | 2024-01-12 | 상하이 한서 바이오메디컬 컴퍼니 리미티드 | 헤테로사이클릭 유도체 억제제 및 이의 제조방법 및 이의 용도 |
CN113278019A (zh) * | 2021-05-31 | 2021-08-20 | 河南偶联生物科技有限公司 | 一种咪唑并[1,2-a]吡啶类化合物的合成方法 |
CN114478423A (zh) * | 2022-03-02 | 2022-05-13 | 八叶草健康产业研究院(厦门)有限公司 | 一种2,4-二甲基恶唑-5-甲酸的制备方法 |
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-
2005
- 2005-06-16 US US11/154,795 patent/US7696210B2/en not_active Expired - Fee Related
- 2005-06-16 KR KR1020067026441A patent/KR20070027584A/ko not_active Application Discontinuation
- 2005-06-16 JP JP2007516680A patent/JP2008503469A/ja active Pending
- 2005-06-16 CA CA002570968A patent/CA2570968A1/en not_active Abandoned
- 2005-06-16 RU RU2007101544/04A patent/RU2007101544A/ru unknown
- 2005-06-16 AU AU2005264996A patent/AU2005264996A1/en not_active Abandoned
- 2005-06-16 CN CNA200580027480XA patent/CN101006078A/zh active Pending
- 2005-06-16 BR BRPI0512261-9A patent/BRPI0512261A/pt not_active IP Right Cessation
- 2005-06-16 EP EP05762686A patent/EP1758895A1/en not_active Withdrawn
- 2005-06-16 MX MXPA06014798A patent/MXPA06014798A/es not_active Application Discontinuation
- 2005-06-16 WO PCT/US2005/021124 patent/WO2006009734A1/en active Application Filing
-
2006
- 2006-12-07 CR CR8799A patent/CR8799A/es not_active Application Discontinuation
- 2006-12-15 ZA ZA200610589A patent/ZA200610589B/en unknown
- 2006-12-18 EC EC2006007090A patent/ECSP067090A/es unknown
-
2007
- 2007-01-16 NO NO20070294A patent/NO20070294L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP1758895A1 (en) | 2007-03-07 |
CR8799A (es) | 2007-08-28 |
ZA200610589B (en) | 2008-07-30 |
AU2005264996A1 (en) | 2006-01-26 |
RU2007101544A (ru) | 2008-08-10 |
ECSP067090A (es) | 2007-01-26 |
KR20070027584A (ko) | 2007-03-09 |
NO20070294L (no) | 2007-02-28 |
CN101006078A (zh) | 2007-07-25 |
CA2570968A1 (en) | 2006-01-26 |
JP2008503469A (ja) | 2008-02-07 |
WO2006009734A8 (en) | 2007-01-11 |
US20060019965A1 (en) | 2006-01-26 |
WO2006009734A1 (en) | 2006-01-26 |
US7696210B2 (en) | 2010-04-13 |
MXPA06014798A (es) | 2007-06-22 |
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