DE602005002751D1 - Substituierte tricyclische benzimidazole - Google Patents

Substituierte tricyclische benzimidazole

Info

Publication number
DE602005002751D1
DE602005002751D1 DE602005002751T DE602005002751T DE602005002751D1 DE 602005002751 D1 DE602005002751 D1 DE 602005002751D1 DE 602005002751 T DE602005002751 T DE 602005002751T DE 602005002751 T DE602005002751 T DE 602005002751T DE 602005002751 D1 DE602005002751 D1 DE 602005002751D1
Authority
DE
Germany
Prior art keywords
substituted tricyclic
tricyclic benzimidazole
benzimidazole
substituted
tricyclic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE602005002751T
Other languages
English (en)
Other versions
DE602005002751T2 (de
Inventor
Christof Brehm
Peter Jan Zimmermann
Wilm Buhr
M Vittoria Chiesa
Andreas Palmer
Stefan Postius
Wolfgang Kromer
Wolfgang-Alexander Simon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Nycomed GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed GmbH filed Critical Nycomed GmbH
Publication of DE602005002751D1 publication Critical patent/DE602005002751D1/de
Application granted granted Critical
Publication of DE602005002751T2 publication Critical patent/DE602005002751T2/de
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE602005002751T 2004-06-09 2005-06-07 Substituierte tricyclische benzimidazole Expired - Fee Related DE602005002751T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP04102628 2004-06-09
EP04102628 2004-06-09
PCT/EP2005/052590 WO2005121139A1 (en) 2004-06-09 2005-06-07 Substituted tricyclic benzimidazoles

Publications (2)

Publication Number Publication Date
DE602005002751D1 true DE602005002751D1 (de) 2007-11-15
DE602005002751T2 DE602005002751T2 (de) 2008-07-17

Family

ID=34929186

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005002751T Expired - Fee Related DE602005002751T2 (de) 2004-06-09 2005-06-07 Substituierte tricyclische benzimidazole

Country Status (10)

Country Link
US (1) US20070244154A1 (de)
EP (1) EP1758900B1 (de)
JP (1) JP2008501766A (de)
AR (1) AR049350A1 (de)
AT (1) ATE374774T1 (de)
AU (1) AU2005251943A1 (de)
CA (1) CA2568856A1 (de)
DE (1) DE602005002751T2 (de)
TW (1) TW200611903A (de)
WO (1) WO2005121139A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI1013288A2 (pt) 2009-07-09 2016-03-29 Raqualia Pharma Inc uso de um composto, método de composição farmacêutica para o tratamento de doenças em que a motilidade gastrointestinal anormal está envolvida, kit e embalagem comercial que compreende uma composição farmacêutica contendo o composto
US10183934B2 (en) 2015-02-02 2019-01-22 Forma Therapeutics, Inc. Bicyclic [4,6,0] hydroxamic acids as HDAC inhibitors
CA2990165C (en) 2015-02-02 2023-12-12 Forma Therapeutics, Inc. 3-aryl-4-amido-bicyclic [4,5,0]hydroxamic acids as hdac inhibitors
EP3472131B1 (de) 2016-06-17 2020-02-19 Forma Therapeutics, Inc. 2-spiro-5- und 6-hydroxamsäureindane als hdac-inhibitoren

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8604566D0 (sv) * 1986-10-27 1986-10-27 Haessle Ab Novel compunds
SE9602286D0 (sv) * 1996-06-10 1996-06-10 Astra Ab New compounds
CA2349476A1 (en) * 1998-11-03 2000-05-11 Byk Gulden Lomberg Chemische Fabrik Gmbh Imidazonaphthyridines
MXPA04001277A (es) * 2001-08-10 2004-05-27 Altana Pharma Ag Imidazopiridinas triciclicas.
US7307084B2 (en) * 2003-04-04 2007-12-11 Altana Pharma Ag Cyclic benzimidazoles

Also Published As

Publication number Publication date
DE602005002751T2 (de) 2008-07-17
TW200611903A (en) 2006-04-16
EP1758900A1 (de) 2007-03-07
ATE374774T1 (de) 2007-10-15
AU2005251943A1 (en) 2005-12-22
WO2005121139A8 (en) 2006-11-23
EP1758900B1 (de) 2007-10-03
US20070244154A1 (en) 2007-10-18
WO2005121139A1 (en) 2005-12-22
CA2568856A1 (en) 2005-12-22
AR049350A1 (es) 2006-07-19
JP2008501766A (ja) 2008-01-24

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee