BRPI0506868A - composições farmacêuticas compreendendo midazolam em uma concentração elevada - Google Patents

composições farmacêuticas compreendendo midazolam em uma concentração elevada

Info

Publication number
BRPI0506868A
BRPI0506868A BRPI0506868-1A BRPI0506868A BRPI0506868A BR PI0506868 A BRPI0506868 A BR PI0506868A BR PI0506868 A BRPI0506868 A BR PI0506868A BR PI0506868 A BRPI0506868 A BR PI0506868A
Authority
BR
Brazil
Prior art keywords
midazolam
pharmaceutical compositions
high concentration
compositions
benzodiazapine
Prior art date
Application number
BRPI0506868-1A
Other languages
English (en)
Inventor
Franciscus Wilhelmus He Merkus
Original Assignee
Franciscus Wilhelmus He Merkus
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Franciscus Wilhelmus He Merkus filed Critical Franciscus Wilhelmus He Merkus
Publication of BRPI0506868A publication Critical patent/BRPI0506868A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Otolaryngology (AREA)
  • Hematology (AREA)
  • Psychiatry (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

COMPOSIçõES FARMACêUTICAS COMPREENDENDO MIDAZOLAM EM UMA CONCENTRAçãO ELEVADA. A presente invenção refere-se à midazolam. Em particular, a invenção fornece novas composições de midazolam para a administração intranasal. Estas comosições contêm midazolam em uma concentração elevada de pelo menos 35 mg/ml.
BRPI0506868-1A 2004-01-14 2005-01-13 composições farmacêuticas compreendendo midazolam em uma concentração elevada BRPI0506868A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0400804.1A GB0400804D0 (en) 2004-01-14 2004-01-14 Pharmaceutical compositions
PCT/EP2005/050133 WO2005067893A2 (en) 2004-01-14 2005-01-13 Pharmaceutical compositions comprising midazolam in a high concentration

Publications (1)

Publication Number Publication Date
BRPI0506868A true BRPI0506868A (pt) 2007-05-29

Family

ID=31726180

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0506868-1A BRPI0506868A (pt) 2004-01-14 2005-01-13 composições farmacêuticas compreendendo midazolam em uma concentração elevada

Country Status (23)

Country Link
US (2) US7700588B2 (pt)
EP (1) EP1703896B1 (pt)
JP (1) JP5085138B2 (pt)
KR (1) KR20060130175A (pt)
CN (1) CN1929816B (pt)
AT (1) ATE417600T1 (pt)
AU (1) AU2005205072B2 (pt)
BR (1) BRPI0506868A (pt)
CA (1) CA2553890C (pt)
DE (1) DE602005011753D1 (pt)
DK (1) DK1703896T3 (pt)
EA (1) EA014096B1 (pt)
ES (1) ES2319667T3 (pt)
FI (2) FIC20230023I1 (pt)
GB (1) GB0400804D0 (pt)
IL (1) IL176774A0 (pt)
MX (1) MXPA06008086A (pt)
NO (3) NO336916B1 (pt)
NZ (1) NZ548454A (pt)
PL (1) PL1703896T3 (pt)
PT (1) PT1703896E (pt)
WO (1) WO2005067893A2 (pt)
ZA (1) ZA200606310B (pt)

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Also Published As

Publication number Publication date
DE602005011753D1 (de) 2009-01-29
ZA200606310B (en) 2007-12-27
IL176774A0 (en) 2006-10-31
AU2005205072A1 (en) 2005-07-28
EP1703896B1 (en) 2008-12-17
GB0400804D0 (en) 2004-02-18
PT1703896E (pt) 2009-02-25
CN1929816A (zh) 2007-03-14
NO2023014I1 (no) 2023-03-21
WO2005067893A3 (en) 2006-04-13
EA200601309A1 (ru) 2006-12-29
FIC20230023I1 (fi) 2023-07-11
ES2319667T3 (es) 2009-05-11
ATE417600T1 (de) 2009-01-15
DK1703896T3 (da) 2009-03-02
KR20060130175A (ko) 2006-12-18
JP5085138B2 (ja) 2012-11-28
FIC20230024I1 (fi) 2023-07-19
JP2007534660A (ja) 2007-11-29
EP1703896A2 (en) 2006-09-27
PL1703896T3 (pl) 2009-06-30
CN1929816B (zh) 2011-08-24
US20050153956A1 (en) 2005-07-14
AU2005205072B2 (en) 2011-03-03
NO336916B1 (no) 2015-11-23
CA2553890A1 (en) 2005-07-28
CA2553890C (en) 2012-10-02
NO2023011I1 (no) 2023-03-16
US20060009447A1 (en) 2006-01-12
WO2005067893A2 (en) 2005-07-28
US7700588B2 (en) 2010-04-20
EA014096B1 (ru) 2010-08-30
MXPA06008086A (es) 2006-12-19
NZ548454A (en) 2010-05-28
NO20063453L (no) 2006-09-26

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