EA200901145A1 - Применение рибофлавина в лечении гипертензии - Google Patents
Применение рибофлавина в лечении гипертензииInfo
- Publication number
- EA200901145A1 EA200901145A1 EA200901145A EA200901145A EA200901145A1 EA 200901145 A1 EA200901145 A1 EA 200901145A1 EA 200901145 A EA200901145 A EA 200901145A EA 200901145 A EA200901145 A EA 200901145A EA 200901145 A1 EA200901145 A1 EA 200901145A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- riboflavin
- treatment
- provides
- patient
- hypertension
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Изобретение предлагает применение рибофлавина в производстве лекарственного средства для лечения или профилактики повышенного артериального давления у пациента, гомозиготного или гетерозиготного на MTHFR C677T полиморфизм. Изобретение также предлагает фармацевтический продукт для лечения или профилактики повышенного артериального давления у пациента, гомозиготного или гетерозиготного на MTHFR C677T полиморфизм, включающий фармацевтически эффективное количество антигипертензивного агента и рибофлавина, и изобретение дополнительно предлагает способ лечения такого пациента, включающий введение рибофлавина.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0703514.0A GB0703514D0 (en) | 2007-02-23 | 2007-02-23 | Use of riboflavin |
PCT/EP2008/001437 WO2008101724A1 (en) | 2007-02-23 | 2008-02-22 | Use of riboflavin in the treatment of hypertension |
Publications (2)
Publication Number | Publication Date |
---|---|
EA200901145A1 true EA200901145A1 (ru) | 2010-02-26 |
EA019281B1 EA019281B1 (ru) | 2014-02-28 |
Family
ID=37945596
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA200901145A EA019281B1 (ru) | 2007-02-23 | 2008-02-22 | Применение рибофлавина в лечении гипертензии |
Country Status (10)
Country | Link |
---|---|
US (1) | US20100324019A1 (ru) |
EP (1) | EP2139488B1 (ru) |
JP (1) | JP5577100B2 (ru) |
CN (1) | CN101678030B (ru) |
CA (1) | CA2679217C (ru) |
EA (1) | EA019281B1 (ru) |
ES (1) | ES2393144T3 (ru) |
GB (1) | GB0703514D0 (ru) |
MX (1) | MX2009009020A (ru) |
WO (1) | WO2008101724A1 (ru) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2656897T3 (es) * | 2012-08-16 | 2018-02-28 | Critical Care Diagnostics, Inc. | Procedimientos de predicción del riesgo de desarrollar hipertensión |
CN103721259A (zh) * | 2014-01-07 | 2014-04-16 | 深圳奥萨医药有限公司 | 血管紧张素ⅱ受体阻断剂/噻嗪类利尿剂/5-甲基四氢叶酸药物组合物 |
CN109295216A (zh) * | 2018-11-06 | 2019-02-01 | 宁波艾捷康宁生物科技有限公司 | 预测高血压个体化药物药效的snp位点和检测试剂盒 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4264601A (en) * | 1979-06-12 | 1981-04-28 | The Board Of Regents Of The University Of Oklahoma | Antihypertensive agents and their use in treatment of hypertension |
DE3682208D1 (de) * | 1986-12-18 | 1991-11-28 | Kurt Heinz Bauer | Gegenueber lichteinfluss stabilisiertes nifedipin-konzentrat und verfahren zu seiner herstellung. |
US6485959B1 (en) * | 1998-10-07 | 2002-11-26 | Cedars Sinai Medical Center | Cell preconditioning and cryopresevation medium |
CN1136895C (zh) * | 2001-05-24 | 2004-02-04 | 魏振鸣 | 一种治疗冠心病的药物 |
WO2006085128A1 (en) * | 2005-02-09 | 2006-08-17 | Wockhardt Limited | Cardiovascular therapeutic combinations |
US7838526B2 (en) * | 2005-08-05 | 2010-11-23 | Esther Baldinger | Method of treating neurological disorders |
-
2007
- 2007-02-23 GB GBGB0703514.0A patent/GB0703514D0/en not_active Ceased
-
2008
- 2008-02-22 MX MX2009009020A patent/MX2009009020A/es active IP Right Grant
- 2008-02-22 EA EA200901145A patent/EA019281B1/ru not_active IP Right Cessation
- 2008-02-22 EP EP08715988A patent/EP2139488B1/en not_active Not-in-force
- 2008-02-22 WO PCT/EP2008/001437 patent/WO2008101724A1/en active Application Filing
- 2008-02-22 CA CA2679217A patent/CA2679217C/en active Active
- 2008-02-22 US US12/528,105 patent/US20100324019A1/en not_active Abandoned
- 2008-02-22 CN CN2008800135209A patent/CN101678030B/zh not_active Expired - Fee Related
- 2008-02-22 JP JP2009550246A patent/JP5577100B2/ja not_active Expired - Fee Related
- 2008-02-22 ES ES08715988T patent/ES2393144T3/es active Active
Also Published As
Publication number | Publication date |
---|---|
CA2679217C (en) | 2016-05-17 |
EA019281B1 (ru) | 2014-02-28 |
MX2009009020A (es) | 2010-02-17 |
EP2139488B1 (en) | 2012-08-15 |
GB0703514D0 (en) | 2007-04-04 |
EP2139488A1 (en) | 2010-01-06 |
CN101678030A (zh) | 2010-03-24 |
WO2008101724A1 (en) | 2008-08-28 |
JP5577100B2 (ja) | 2014-08-20 |
US20100324019A1 (en) | 2010-12-23 |
JP2010519235A (ja) | 2010-06-03 |
CA2679217A1 (en) | 2008-08-28 |
WO2008101724A8 (en) | 2009-10-08 |
CN101678030B (zh) | 2013-06-05 |
ES2393144T3 (es) | 2012-12-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ BY KZ KG MD TJ TM RU |