BRPI0517976A - métodos de tratamento - Google Patents
métodos de tratamentoInfo
- Publication number
- BRPI0517976A BRPI0517976A BRPI0517976-9A BRPI0517976A BRPI0517976A BR PI0517976 A BRPI0517976 A BR PI0517976A BR PI0517976 A BRPI0517976 A BR PI0517976A BR PI0517976 A BRPI0517976 A BR PI0517976A
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- treatment methods
- patient
- treatment
- temozolomide
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/91—Transferases (2.)
- G01N2333/91005—Transferases (2.) transferring one-carbon groups (2.1)
- G01N2333/91011—Methyltransferases (general) (2.1.1.)
- G01N2333/91017—Methyltransferases (general) (2.1.1.) with definite EC number (2.1.1.-)
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
MéTODOS DE TRATAMENTO. Trata-se de métodos para tratar câncer em um paciente necessitado de tal tratamento que compreende administrar temozolomida de acordo com um regime e/ou programas de dosagem aperfeiçoados baseados no nível de MGMT do paciente. Métodos aperfeiçoados adicionais para tratar os pacientes com temozolomida também são descritos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US62625804P | 2004-11-09 | 2004-11-09 | |
PCT/US2005/040449 WO2006052976A2 (en) | 2004-11-09 | 2005-11-07 | Improved dosing regimen of temozolomide for treating cancer based on the patient’s mgmt level |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0517976A true BRPI0517976A (pt) | 2008-10-21 |
Family
ID=36168622
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0517976-9A BRPI0517976A (pt) | 2004-11-09 | 2005-11-07 | métodos de tratamento |
Country Status (13)
Country | Link |
---|---|
US (2) | US20060100188A1 (pt) |
EP (1) | EP1830845A2 (pt) |
JP (2) | JP2008519584A (pt) |
CN (1) | CN101098696A (pt) |
AU (1) | AU2005304672B2 (pt) |
BR (1) | BRPI0517976A (pt) |
CA (1) | CA2585446A1 (pt) |
MX (1) | MX2007005581A (pt) |
NO (1) | NO20072931L (pt) |
NZ (1) | NZ554831A (pt) |
TW (1) | TW200630089A (pt) |
WO (1) | WO2006052976A2 (pt) |
ZA (1) | ZA200703716B (pt) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2476494C (en) * | 2002-02-22 | 2010-04-27 | Schering Corporation | Pharmaceutical formulations of antineoplastic agents, in particular temozolomide, processes of making and using the same |
US20060100188A1 (en) * | 2004-11-09 | 2006-05-11 | Chen Zong | Treatment methods |
US20070111979A1 (en) * | 2005-11-07 | 2007-05-17 | Walter Robert Bishop | Methods of treating cell proliferative disorders using a compressed temozolomide dosing schedule |
US20070265324A1 (en) * | 2006-01-17 | 2007-11-15 | Wolfgang Wernet | Combination Therapy with Parp Inhibitors |
PT2004646T (pt) | 2006-04-05 | 2016-07-14 | Opko Health Inc | Sais cloridrato de 8-[{1-(3,5-bis-(trifluorometil)fenil)- etoxi} -metil]-8-fenil-1,7-diazaespiro[4.5]decan-2-ona e processo para a sua preparação |
SG10201500028RA (en) | 2006-04-05 | 2015-02-27 | Opko Health Inc | Pharmaceutical formulations: salts of 8-[{1-(3,5-bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one and treatment methods using the same |
WO2007133496A2 (en) * | 2006-05-09 | 2007-11-22 | Schering Corporation | Development of a novel assay for mgmt (methyl guanine transferase) |
AR061618A1 (es) * | 2006-06-26 | 2008-09-10 | Schering Corp | Formas de dosificacion unitaria de temozolomida |
EP2409700A1 (en) * | 2007-05-08 | 2012-01-25 | Schering Corporation | Methods of treatment using intravenous formulations comprising temozolomide |
US20080319039A1 (en) * | 2007-06-25 | 2008-12-25 | Jacqueline Rose Bersch | Unit dosage forms of temozolomide |
US8435972B2 (en) * | 2010-09-02 | 2013-05-07 | Emory University | Method for the treatment of central nervous system cancers and compositions related thereto |
CA2908353C (en) * | 2013-04-17 | 2021-11-02 | Signal Pharmaceuticals, Llc | Treatment of cancer with dihydropyrazino-pyrazines |
CN110408694A (zh) * | 2018-04-26 | 2019-11-05 | 胤安国际(辽宁)基因科技股份有限公司 | 评估替莫唑胺在治疗脑胶质瘤患者的敏感性的新方法 |
MX2021011760A (es) * | 2019-03-28 | 2021-12-10 | Univ Jefferson | Metodos para el tratamiento de canceres usando antisentido. |
WO2023113538A1 (ko) * | 2021-12-17 | 2023-06-22 | 숙명여자대학교산학협력단 | 뇌종양 치료를 위한 글리세오플빈 병용요법 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5260291A (en) * | 1981-08-24 | 1993-11-09 | Cancer Research Campaign Technology Limited | Tetrazine derivatives |
US5876146A (en) * | 1995-10-27 | 1999-03-02 | General Electric Company | Apparatus and methods for repairing jet pump diffusers in a nuclear reactor |
US6017704A (en) * | 1996-06-03 | 2000-01-25 | The Johns Hopkins University School Of Medicine | Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids |
US5786146A (en) * | 1996-06-03 | 1998-07-28 | The Johns Hopkins University School Of Medicine | Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids |
US5939098A (en) * | 1996-09-19 | 1999-08-17 | Schering Corporation | Cancer treatment with temozolomide |
BR0009380A (pt) * | 1999-03-30 | 2001-12-26 | Schering Corp | Tratamento de câncer melhorado comtemozolomida |
US6346524B1 (en) * | 1999-03-30 | 2002-02-12 | Schering Corporation | Cancer treatment with temozolomide |
WO2001085221A2 (en) * | 2000-05-12 | 2001-11-15 | Duke University | Assessing levels of o6-alkylguanine-dna alkyltransferase in vivo |
JP2004509643A (ja) * | 2000-09-29 | 2004-04-02 | ザ ジョンズ ホプキンス ユニバーシティー スクール オブ メディシン | アルキル化剤を用いた化学療法による治療に対する臨床反応を予測する方法 |
WO2002103013A2 (en) * | 2000-10-30 | 2002-12-27 | Gene Logic, Inc. | Partially double-stranded nucleic acids, methods of making, and use thereof |
EP1344777B1 (en) * | 2000-11-20 | 2011-03-16 | Takeda Pharmaceutical Company Limited | Imidazole derivatives, process for their preparation and their use |
US20060183168A1 (en) * | 2002-10-28 | 2006-08-17 | Geroni Maria C | Method for optimizing therapeutic efficacy of nemorubicin |
WO2004086949A2 (en) * | 2003-03-25 | 2004-10-14 | John Wayne Cancer Institute | Dna markers for management of cancer |
US20060100188A1 (en) * | 2004-11-09 | 2006-05-11 | Chen Zong | Treatment methods |
US20070111979A1 (en) * | 2005-11-07 | 2007-05-17 | Walter Robert Bishop | Methods of treating cell proliferative disorders using a compressed temozolomide dosing schedule |
-
2005
- 2005-11-07 US US11/268,160 patent/US20060100188A1/en not_active Abandoned
- 2005-11-07 AU AU2005304672A patent/AU2005304672B2/en not_active Ceased
- 2005-11-07 NZ NZ554831A patent/NZ554831A/en not_active IP Right Cessation
- 2005-11-07 CA CA002585446A patent/CA2585446A1/en not_active Abandoned
- 2005-11-07 WO PCT/US2005/040449 patent/WO2006052976A2/en active Application Filing
- 2005-11-07 CN CNA2005800461914A patent/CN101098696A/zh active Pending
- 2005-11-07 MX MX2007005581A patent/MX2007005581A/es unknown
- 2005-11-07 BR BRPI0517976-9A patent/BRPI0517976A/pt not_active IP Right Cessation
- 2005-11-07 EP EP05851437A patent/EP1830845A2/en not_active Withdrawn
- 2005-11-07 JP JP2007540176A patent/JP2008519584A/ja active Pending
- 2005-11-08 TW TW094139158A patent/TW200630089A/zh unknown
-
2007
- 2007-05-08 ZA ZA200703716A patent/ZA200703716B/xx unknown
- 2007-06-08 NO NO20072931A patent/NO20072931L/no not_active Application Discontinuation
-
2009
- 2009-02-25 US US12/392,591 patent/US20090247598A1/en not_active Abandoned
-
2011
- 2011-01-11 JP JP2011003480A patent/JP2011121960A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
JP2011121960A (ja) | 2011-06-23 |
US20060100188A1 (en) | 2006-05-11 |
ZA200703716B (en) | 2008-09-25 |
EP1830845A2 (en) | 2007-09-12 |
MX2007005581A (es) | 2007-05-23 |
AU2005304672A1 (en) | 2006-05-18 |
AU2005304672B2 (en) | 2010-03-11 |
NO20072931L (no) | 2007-08-03 |
NZ554831A (en) | 2009-10-30 |
US20090247598A1 (en) | 2009-10-01 |
TW200630089A (en) | 2006-09-01 |
WO2006052976A2 (en) | 2006-05-18 |
CN101098696A (zh) | 2008-01-02 |
WO2006052976A3 (en) | 2006-08-17 |
CA2585446A1 (en) | 2006-05-18 |
JP2008519584A (ja) | 2008-06-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 8A ANUIDADE. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2260 DE 29/04/2014. |