WO2006116582A3 - Pharmaceutical compositions comprising a substituted benzimidazole, buffering agent and vitamin b12 - Google Patents

Pharmaceutical compositions comprising a substituted benzimidazole, buffering agent and vitamin b12 Download PDF

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Publication number
WO2006116582A3
WO2006116582A3 PCT/US2006/015982 US2006015982W WO2006116582A3 WO 2006116582 A3 WO2006116582 A3 WO 2006116582A3 US 2006015982 W US2006015982 W US 2006015982W WO 2006116582 A3 WO2006116582 A3 WO 2006116582A3
Authority
WO
WIPO (PCT)
Prior art keywords
vitamin
pharmaceutical compositions
buffering agent
substituted benzimidazole
compositions
Prior art date
Application number
PCT/US2006/015982
Other languages
French (fr)
Other versions
WO2006116582A2 (en
Inventor
Jeffrey Phillips
Original Assignee
Univ Missouri
Jeffrey Phillips
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Missouri, Jeffrey Phillips filed Critical Univ Missouri
Publication of WO2006116582A2 publication Critical patent/WO2006116582A2/en
Publication of WO2006116582A3 publication Critical patent/WO2006116582A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7135—Compounds containing heavy metals
    • A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12

Abstract

The present invention relates to, inter alia, pharmaceutical compositions comprising one or more of an acid labile proton pump inhibitor, a buffering agent, and vitamin B12; to methods for manufacture of such compositions, and to use of such compositions in treating and preventing diseases and/or disorders.
PCT/US2006/015982 2005-04-26 2006-04-25 Pharmaceutical compositions comprising a substituted benzimidazole, buffering agent and vitamin b12 WO2006116582A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67513305P 2005-04-26 2005-04-26
US60/675,133 2005-04-26

Publications (2)

Publication Number Publication Date
WO2006116582A2 WO2006116582A2 (en) 2006-11-02
WO2006116582A3 true WO2006116582A3 (en) 2007-07-26

Family

ID=37215496

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/015982 WO2006116582A2 (en) 2005-04-26 2006-04-25 Pharmaceutical compositions comprising a substituted benzimidazole, buffering agent and vitamin b12

Country Status (1)

Country Link
WO (1) WO2006116582A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8247440B2 (en) * 2008-02-20 2012-08-21 Curators Of The University Of Missouri Composition comprising omeprazole, lansoprazole and at least one buffering agent
EP3288556A4 (en) 2015-04-29 2018-09-19 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6489346B1 (en) * 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US6645988B2 (en) * 1996-01-04 2003-11-11 Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
WO2004028268A1 (en) * 2002-09-24 2004-04-08 Gumlink A/S Chewing gum comprising at least two different biodegradable polymers
US20050087198A1 (en) * 2002-02-12 2005-04-28 Bruno-Raimondi Alfredo E. Method for systemic drug delivery through the nail
US20050112193A1 (en) * 2003-07-23 2005-05-26 Phillips Jeffrey O. Immediate-release formulations of acid-labile pharmaceutical compositions

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6489346B1 (en) * 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US6645988B2 (en) * 1996-01-04 2003-11-11 Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US20050087198A1 (en) * 2002-02-12 2005-04-28 Bruno-Raimondi Alfredo E. Method for systemic drug delivery through the nail
WO2004028268A1 (en) * 2002-09-24 2004-04-08 Gumlink A/S Chewing gum comprising at least two different biodegradable polymers
US20050112193A1 (en) * 2003-07-23 2005-05-26 Phillips Jeffrey O. Immediate-release formulations of acid-labile pharmaceutical compositions

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
SCHENK B. ET AL.: "A trophic Gastritis During Long-term Omeprazole Therapy Affects Serum Vitamin B12 Levels", ALIMENT PHARMACOL. THER., vol. 13, 1999, pages 1343 - 1346, XP003015905 *
TERMANINI B.: "Effect of Long-Term Gastric Acid Suppressive Therapy on Serum Vitamin B12 Levels in Patients with Zollinger-Ellison Syndrome", THE AMERICAN JOURNAL OF MEDICINE, vol. 104, May 1998 (1998-05-01), pages 422 - 430, XP003015906 *

Also Published As

Publication number Publication date
WO2006116582A2 (en) 2006-11-02

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