NO20063453L - Farmasoytiske sammensetninger omfattende midazolam i en hoy konsentrasjon - Google Patents
Farmasoytiske sammensetninger omfattende midazolam i en hoy konsentrasjonInfo
- Publication number
- NO20063453L NO20063453L NO20063453A NO20063453A NO20063453L NO 20063453 L NO20063453 L NO 20063453L NO 20063453 A NO20063453 A NO 20063453A NO 20063453 A NO20063453 A NO 20063453A NO 20063453 L NO20063453 L NO 20063453L
- Authority
- NO
- Norway
- Prior art keywords
- midazolam
- pharmaceutical compositions
- high concentration
- compositions
- benzodiazapine
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
- A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Otolaryngology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Rheumatology (AREA)
- Anesthesiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Det beskrives administrering av midazolam, særlig beskrives nye midazolamblandinger for intranasal administrering. Disse blandingene inneholder midazolam i en høy konsentrasjon på minst 35 mg/mL.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0400804.1A GB0400804D0 (en) | 2004-01-14 | 2004-01-14 | Pharmaceutical compositions |
PCT/EP2005/050133 WO2005067893A2 (en) | 2004-01-14 | 2005-01-13 | Pharmaceutical compositions comprising midazolam in a high concentration |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20063453L true NO20063453L (no) | 2006-09-26 |
NO336916B1 NO336916B1 (no) | 2015-11-23 |
Family
ID=31726180
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20063453A NO336916B1 (no) | 2004-01-14 | 2006-07-26 | Farmasøytisk blanding for intranasal administrering og anvendelse derav, samt en innretning for intranasal levering |
NO2023011C NO2023011I1 (no) | 2004-01-14 | 2023-03-16 | Midazolam, optionally in the form of a pharmaceutically acceptable salt, in particular Midazolam HCl, formulated in combination with ethanol |
NO2023014C NO2023014I1 (no) | 2004-01-14 | 2023-03-21 | Midazolam HCl in ethanol/propylene glycol solubilized form |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO2023011C NO2023011I1 (no) | 2004-01-14 | 2023-03-16 | Midazolam, optionally in the form of a pharmaceutically acceptable salt, in particular Midazolam HCl, formulated in combination with ethanol |
NO2023014C NO2023014I1 (no) | 2004-01-14 | 2023-03-21 | Midazolam HCl in ethanol/propylene glycol solubilized form |
Country Status (23)
Country | Link |
---|---|
US (2) | US7700588B2 (no) |
EP (1) | EP1703896B1 (no) |
JP (1) | JP5085138B2 (no) |
KR (1) | KR20060130175A (no) |
CN (1) | CN1929816B (no) |
AT (1) | ATE417600T1 (no) |
AU (1) | AU2005205072B2 (no) |
BR (1) | BRPI0506868A (no) |
CA (1) | CA2553890C (no) |
DE (1) | DE602005011753D1 (no) |
DK (1) | DK1703896T3 (no) |
EA (1) | EA014096B1 (no) |
ES (1) | ES2319667T3 (no) |
FI (2) | FIC20230023I1 (no) |
GB (1) | GB0400804D0 (no) |
IL (1) | IL176774A0 (no) |
MX (1) | MXPA06008086A (no) |
NO (3) | NO336916B1 (no) |
NZ (1) | NZ548454A (no) |
PL (1) | PL1703896T3 (no) |
PT (1) | PT1703896E (no) |
WO (1) | WO2005067893A2 (no) |
ZA (1) | ZA200606310B (no) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040176359A1 (en) * | 2001-02-20 | 2004-09-09 | University Of Kentucky Research Foundation | Intranasal Benzodiazepine compositions |
PL2623113T3 (pl) | 2005-11-09 | 2018-05-30 | Onyx Therapeutics, Inc. | Związek do hamowania enzymu |
EP2484688B1 (en) | 2006-06-19 | 2016-06-08 | Onyx Therapeutics, Inc. | Peptide epoxyketones for proteasome inhibition |
ES2611995T3 (es) * | 2007-01-19 | 2017-05-11 | Hananja Ehf | Métodos y composiciones para el suministro de un agente terapéutico |
US20080275030A1 (en) | 2007-01-19 | 2008-11-06 | Sveinbjorn Gizurarson | Methods and Compositions for the Delivery of a Therapeutic Agent |
JP5539875B2 (ja) | 2007-08-31 | 2014-07-02 | アルキメデス・デベロップメント・リミテッド | 非水性医薬組成物 |
US8507468B2 (en) * | 2007-10-02 | 2013-08-13 | Robert Orr | Intranasal anti-convulsive compositions and methods |
US8367617B2 (en) | 2007-10-04 | 2013-02-05 | Onyx Therapeutics, Inc. | Crystalline peptide epoxy ketone protease inhibitors and the synthesis of amino acid keto-epoxides |
US20090258865A1 (en) | 2008-03-28 | 2009-10-15 | Hale Biopharma Ventures, Llc | Administration of benzodiazepine compositions |
EP3090737A1 (en) | 2008-10-21 | 2016-11-09 | Onyx Therapeutics, Inc. | Combination therapy with peptide epoxyketones |
AR075899A1 (es) | 2009-03-20 | 2011-05-04 | Onyx Therapeutics Inc | Tripeptidos epoxicetonas cristalinos inhibidores de proteasa |
US8853147B2 (en) | 2009-11-13 | 2014-10-07 | Onyx Therapeutics, Inc. | Use of peptide epoxyketones for metastasis suppression |
JP6042724B2 (ja) | 2010-03-01 | 2016-12-14 | オニキス セラピューティクス, インク.Onyx Therapeutics, Inc. | イムノプロテアソーム阻害のための化合物 |
EP2555621A4 (en) | 2010-04-07 | 2014-07-02 | Onyx Therapeutics Inc | CRYSTALLINE EPOXYCETONE PEPTIDE IMMUNOPROTEASOME INHIBITOR |
GB2481407B (en) * | 2010-06-22 | 2012-05-23 | Special Products Ltd | A rapid onset liquid midazolam composition for buccal administration |
CN102309438B (zh) * | 2010-07-02 | 2013-04-17 | 中国人民解放军军事医学科学院毒物药物研究所 | 一种咪达唑仑药物组合物及其用途 |
CN102335430B (zh) * | 2010-07-14 | 2013-07-31 | 中国人民解放军军事医学科学院毒物药物研究所 | 包含咪达唑仑与神经保护剂的复方药物组合物 |
CN102462685B (zh) * | 2010-11-10 | 2014-07-30 | 中国人民解放军军事医学科学院毒物药物研究所 | 一种咪达唑仑组合物、其制备方法及用途 |
CN107260672A (zh) | 2011-05-13 | 2017-10-20 | 欧洲凯尔特公司 | 包含纳洛酮的鼻内药物剂型 |
TW201414751A (zh) | 2012-07-09 | 2014-04-16 | 歐尼克斯治療公司 | 肽環氧酮蛋白酶抑制劑之前驅藥物 |
US9561177B2 (en) | 2014-03-14 | 2017-02-07 | Adapt Pharma Limited | Nasal drug products and methods of their use |
US10085937B2 (en) | 2014-03-14 | 2018-10-02 | Adapt Pharma Limited | Nasal drug products and methods of their use |
US20200297734A1 (en) * | 2015-06-19 | 2020-09-24 | Melt Pharmaceuticals, Inc. | Pharmaceutical compositions and methods for anesthesiological applications |
US11045462B2 (en) * | 2016-06-14 | 2021-06-29 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Methods for treating neurological conditions and exposure to nerve agents |
WO2019226753A1 (en) | 2018-05-25 | 2019-11-28 | Ucb Biopharma Sprl | Benzodiazepine formulations |
WO2020129085A1 (en) | 2018-12-18 | 2020-06-25 | Cipla Limited | Intranasal formulation |
US20210322343A1 (en) * | 2020-04-15 | 2021-10-21 | Farzana Shaheen | Nasally administered pharmaceutical composition for the treatment of epilepsy and related disorders |
CN113209013B (zh) * | 2021-06-24 | 2023-04-07 | 新疆特丰药业股份有限公司 | 一种咪达唑仑液体制剂及其制备方法和用途 |
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NL2031331B1 (en) | 2022-03-18 | 2023-09-29 | Plethora Therapeutics B V | Transmucosal delivery of a short-acting psychedelic compound |
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-
2004
- 2004-01-14 GB GBGB0400804.1A patent/GB0400804D0/en not_active Ceased
-
2005
- 2005-01-13 CN CN2005800078503A patent/CN1929816B/zh active Active
- 2005-01-13 BR BRPI0506868-1A patent/BRPI0506868A/pt not_active Application Discontinuation
- 2005-01-13 NZ NZ548454A patent/NZ548454A/en unknown
- 2005-01-13 JP JP2006548318A patent/JP5085138B2/ja active Active
- 2005-01-13 US US11/034,474 patent/US7700588B2/en active Active
- 2005-01-13 PT PT05701515T patent/PT1703896E/pt unknown
- 2005-01-13 PL PL05701515T patent/PL1703896T3/pl unknown
- 2005-01-13 WO PCT/EP2005/050133 patent/WO2005067893A2/en active Application Filing
- 2005-01-13 CA CA2553890A patent/CA2553890C/en active Active
- 2005-01-13 MX MXPA06008086A patent/MXPA06008086A/es unknown
- 2005-01-13 DE DE602005011753T patent/DE602005011753D1/de active Active
- 2005-01-13 EA EA200601309A patent/EA014096B1/ru not_active IP Right Cessation
- 2005-01-13 KR KR1020067016194A patent/KR20060130175A/ko not_active Application Discontinuation
- 2005-01-13 AT AT05701515T patent/ATE417600T1/de active
- 2005-01-13 AU AU2005205072A patent/AU2005205072B2/en active Active
- 2005-01-13 DK DK05701515T patent/DK1703896T3/da active
- 2005-01-13 ES ES05701515T patent/ES2319667T3/es active Active
- 2005-01-13 EP EP05701515A patent/EP1703896B1/en active Active
- 2005-09-08 US US11/221,663 patent/US20060009447A1/en not_active Abandoned
-
2006
- 2006-07-10 IL IL176774A patent/IL176774A0/en unknown
- 2006-07-26 NO NO20063453A patent/NO336916B1/no active Protection Beyond IP Right Term
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