BRPI0415308A - incorporação especìfica de local de aminoácidos redox ativos em proteìnas - Google Patents
incorporação especìfica de local de aminoácidos redox ativos em proteìnasInfo
- Publication number
- BRPI0415308A BRPI0415308A BRPI0415308-1A BRPI0415308A BRPI0415308A BR PI0415308 A BRPI0415308 A BR PI0415308A BR PI0415308 A BRPI0415308 A BR PI0415308A BR PI0415308 A BRPI0415308 A BR PI0415308A
- Authority
- BR
- Brazil
- Prior art keywords
- amino acids
- proteins
- active redox
- redox amino
- site
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 5
- 108090000623 proteins and genes Proteins 0.000 title abstract 5
- 150000001413 amino acids Chemical class 0.000 title abstract 4
- 238000010348 incorporation Methods 0.000 title 1
- 108020004566 Transfer RNA Proteins 0.000 abstract 2
- 102000052866 Amino Acyl-tRNA Synthetases Human genes 0.000 abstract 1
- 108700028939 Amino Acyl-tRNA Synthetases Proteins 0.000 abstract 1
- 102000003960 Ligases Human genes 0.000 abstract 1
- 108090000364 Ligases Proteins 0.000 abstract 1
- 125000000266 alpha-aminoacyl group Chemical group 0.000 abstract 1
- 230000001851 biosynthetic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51153203P | 2003-10-14 | 2003-10-14 | |
| PCT/US2004/034089 WO2005038002A2 (en) | 2003-10-14 | 2004-10-13 | Site-specific incorporation of redox active amino acids into proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0415308A true BRPI0415308A (pt) | 2006-12-05 |
Family
ID=34465242
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0415308-1A BRPI0415308A (pt) | 2003-10-14 | 2004-10-13 | incorporação especìfica de local de aminoácidos redox ativos em proteìnas |
Country Status (14)
| Country | Link |
|---|---|
| US (5) | US7494796B2 (enExample) |
| EP (1) | EP1687401B1 (enExample) |
| JP (1) | JP5657850B2 (enExample) |
| CN (2) | CN101532046A (enExample) |
| AU (1) | AU2004282577B2 (enExample) |
| BR (1) | BRPI0415308A (enExample) |
| CA (1) | CA2541166A1 (enExample) |
| DK (1) | DK1687401T3 (enExample) |
| ES (1) | ES2396712T3 (enExample) |
| IL (3) | IL174947A (enExample) |
| MX (1) | MXPA06004087A (enExample) |
| PL (1) | PL1687401T3 (enExample) |
| PT (1) | PT1687401E (enExample) |
| WO (1) | WO2005038002A2 (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2322631T3 (en) * | 2001-04-19 | 2015-01-12 | Scripps Research Inst | Methods and compositions for the production of orthogonal tRNA-aminoacyl-tRNA syntetasepar |
| ES2333422T3 (es) * | 2002-10-16 | 2010-02-22 | The Scripps Research Institute | Sintesis de glicoproteinas. |
| EP1613735B1 (en) | 2003-04-17 | 2012-01-25 | The Scripps Research Institute | Expanding the eukaryotic genetic code |
| CN102618605B (zh) | 2003-06-18 | 2015-09-02 | 斯克利普斯研究院 | 非天然活性氨基酸遗传密码增加 |
| ATE471385T1 (de) | 2003-07-07 | 2010-07-15 | Scripps Research Inst | Zusammensetzungen aus orthogonalen lysyl-trna- und aminoacyl-trna-synthetasepaaren und deren verwendung |
| JP2008500050A (ja) * | 2004-05-25 | 2008-01-10 | ザ スクリップス リサーチ インスティテュート | 結晶構造決定のための重原子含有非天然アミノ酸の部位特異的蛋白質組込み |
| DE102004031258A1 (de) * | 2004-06-29 | 2006-02-09 | Jennissen, Herbert P., Prof. Dr. | Proteinhybride mit polyhydroxyaromatischen Aminosäure-Epitopen |
| JP2008513806A (ja) * | 2004-09-22 | 2008-05-01 | ザ スクリップス リサーチ インスティテュート | Ｎｍｒ試験のための蛋白質の部位特異的標識 |
| EP1807515A4 (en) | 2004-10-27 | 2008-06-18 | Scripps Research Inst | Orthogonal translation components for the in vivo incorporation of unnatural amino acids |
| US8367588B2 (en) * | 2005-10-12 | 2013-02-05 | The Scripps Research Institute | Selective posttranslational modification of phage-displayed polypeptides |
| US7776535B2 (en) * | 2006-02-06 | 2010-08-17 | Franklin And Marshall College | Site-specific incorporation of fluorinated amino acids into proteins |
| US7960141B2 (en) * | 2006-03-09 | 2011-06-14 | The Scripps Research Institute | Systems for the expression of orthogonal translation components in eubacterial host cells |
| AU2007227592B2 (en) | 2006-03-16 | 2011-11-24 | The Scripps Research Institute | Genetically programmed expression of proteins containing the unnatural amino acid phenylselenocysteine |
| CA2652894A1 (en) * | 2006-05-23 | 2007-12-06 | The Scripps Research Institute | Genetically encoded fluorescent coumarin amino acids |
| PT2052083E (pt) * | 2006-09-21 | 2014-04-10 | Scripps Research Inst | Expressão geneticamente programada de proteínas seletivamente sulfatadas em eubactérias |
| US9624485B2 (en) | 2006-10-18 | 2017-04-18 | The Scripps Research Institute | Genetic incorporation of unnatural amino acids into proteins in mammalian cells |
| WO2008137452A1 (en) * | 2007-05-04 | 2008-11-13 | Kenergy Royalty Company, Llc | Implantable high efficiency digital stimulation device |
| MX2010004464A (es) | 2007-10-25 | 2010-06-07 | Scripps Research Inst | Incorporacion genetica de 3-aminotirosina a reductasas. |
| EP2220218A4 (en) * | 2007-11-02 | 2010-12-08 | Scripps Research Inst | GENETICALLY ENCODED BORONATE AMINO ACID |
| US9249408B2 (en) * | 2007-11-02 | 2016-02-02 | The Scripps Research Institute | Directed evolution using proteins comprising unnatural amino acids |
| KR20100105846A (ko) * | 2007-12-11 | 2010-09-30 | 더 스크립스 리서치 인스티튜트 | 메틸영양요구성 효모 피키아 파스토리스에서의 생체 내 비천연 아미노산 발현 |
| KR20100125290A (ko) * | 2008-02-08 | 2010-11-30 | 더 스크립스 리서치 인스티튜트 | 유전적으로 코딩된 비천연 아미노산에 의한 면역 내성의 파괴 |
| WO2010077608A1 (en) * | 2008-12-09 | 2010-07-08 | Wilson-Cook Medical Inc. | Apparatus and methods for controlled release of tacking devices |
| JP5959201B2 (ja) | 2008-12-10 | 2016-08-02 | ザ スクリプス リサーチ インスティテュート | 化学的に反応性の非天然アミノ酸を使用するキャリア−ペプチド接合体の製造 |
| US20090197339A1 (en) * | 2008-12-10 | 2009-08-06 | The Scripps Research Institute | In vivo unnatural amino acid expression in the methylotrophic yeast pichia pastoris |
| EP2394323B1 (en) * | 2009-02-04 | 2017-05-24 | Ben-gurion University Of The Negev Research And Development Authority | Systems and methods for bio-electricity production |
| WO2014146575A1 (en) | 2013-03-19 | 2014-09-25 | Beijing Shenogen Pharma Group Ltd. | Antibodies and methods for treating estrogen receptor-associated diseases |
| US20150331624A1 (en) * | 2014-05-19 | 2015-11-19 | Kabushiki Kaisha Toshiba | Host-controlled flash translation layer snapshot |
| KR101956042B1 (ko) * | 2017-07-13 | 2019-03-08 | 서강대학교산학협력단 | 표적 단백질 내 l-디하이드록시페닐알라닌의 도입 방법 |
| CN114008176A (zh) | 2019-06-17 | 2022-02-01 | 默克专利股份有限公司 | 基于液晶的光阀 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5879905A (en) * | 1996-08-29 | 1999-03-09 | Massachusetts Institute Of Technology | In vivo method of initiating protein synthesis with an amino acid other than methionine |
| DK2322631T3 (en) * | 2001-04-19 | 2015-01-12 | Scripps Research Inst | Methods and compositions for the production of orthogonal tRNA-aminoacyl-tRNA syntetasepar |
| DK1578949T3 (da) | 2002-10-16 | 2009-07-27 | Scripps Research Inst | Stedspecifik optagelse af keto-aminnosyrer hos proteiner |
| ES2333422T3 (es) | 2002-10-16 | 2010-02-22 | The Scripps Research Institute | Sintesis de glicoproteinas. |
| MXPA05006836A (es) | 2002-12-22 | 2005-08-16 | Scripps Research Inst | Colecciones ordenadas de proteinas. |
| EP1613735B1 (en) | 2003-04-17 | 2012-01-25 | The Scripps Research Institute | Expanding the eukaryotic genetic code |
| CN102618605B (zh) | 2003-06-18 | 2015-09-02 | 斯克利普斯研究院 | 非天然活性氨基酸遗传密码增加 |
| US20060160175A1 (en) | 2003-07-07 | 2006-07-20 | The Scripps Research Institute | Compositions of orthogonal leucyl-trna and aminoacyl-trna synthetase pairs and uses thereof |
| ATE471385T1 (de) | 2003-07-07 | 2010-07-15 | Scripps Research Inst | Zusammensetzungen aus orthogonalen lysyl-trna- und aminoacyl-trna-synthetasepaaren und deren verwendung |
| WO2005007624A2 (en) | 2003-07-07 | 2005-01-27 | The Scripps Research Institute | Compositions of orthogonal glutamyl-trna and aminoacyl trna synthetase pairs and uses thereof |
-
2004
- 2004-10-13 CA CA002541166A patent/CA2541166A1/en not_active Abandoned
- 2004-10-13 MX MXPA06004087A patent/MXPA06004087A/es active IP Right Grant
- 2004-10-13 EP EP04795276A patent/EP1687401B1/en not_active Expired - Lifetime
- 2004-10-13 US US10/965,218 patent/US7494796B2/en not_active Expired - Lifetime
- 2004-10-13 AU AU2004282577A patent/AU2004282577B2/en not_active Ceased
- 2004-10-13 ES ES04795276T patent/ES2396712T3/es not_active Expired - Lifetime
- 2004-10-13 PL PL04795276T patent/PL1687401T3/pl unknown
- 2004-10-13 BR BRPI0415308-1A patent/BRPI0415308A/pt not_active IP Right Cessation
- 2004-10-13 WO PCT/US2004/034089 patent/WO2005038002A2/en not_active Ceased
- 2004-10-13 DK DK04795276.7T patent/DK1687401T3/da active
- 2004-10-13 CN CN200910004743A patent/CN101532046A/zh active Pending
- 2004-10-13 JP JP2006535350A patent/JP5657850B2/ja not_active Expired - Fee Related
- 2004-10-13 US US10/575,991 patent/US8008041B2/en not_active Expired - Lifetime
- 2004-10-13 CN CN2004800301376A patent/CN1942579B/zh not_active Expired - Fee Related
- 2004-10-13 PT PT47952767T patent/PT1687401E/pt unknown
-
2006
- 2006-04-11 IL IL174947A patent/IL174947A/en not_active IP Right Cessation
-
2008
- 2008-12-17 US US12/317,034 patent/US7811801B2/en not_active Expired - Lifetime
-
2009
- 2009-10-22 IL IL201705A patent/IL201705A0/en unknown
-
2010
- 2010-07-08 IL IL206889A patent/IL206889A0/en unknown
- 2010-08-20 US US12/806,751 patent/US8114654B2/en not_active Expired - Lifetime
-
2012
- 2012-01-05 US US13/344,436 patent/US9783798B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2541166A1 (en) | 2005-04-28 |
| IL201705A0 (en) | 2011-08-01 |
| JP2007508034A (ja) | 2007-04-05 |
| PT1687401E (pt) | 2013-02-26 |
| US20120100570A1 (en) | 2012-04-26 |
| EP1687401A4 (en) | 2007-08-01 |
| IL174947A0 (en) | 2006-08-20 |
| EP1687401A2 (en) | 2006-08-09 |
| AU2004282577B2 (en) | 2009-10-29 |
| CN1942579A (zh) | 2007-04-04 |
| US9783798B2 (en) | 2017-10-10 |
| WO2005038002A2 (en) | 2005-04-28 |
| US20110008782A1 (en) | 2011-01-13 |
| DK1687401T3 (da) | 2013-02-04 |
| CN101532046A (zh) | 2009-09-16 |
| ES2396712T3 (es) | 2013-02-25 |
| MXPA06004087A (es) | 2006-06-27 |
| WO2005038002A3 (en) | 2006-11-23 |
| PL1687401T3 (pl) | 2013-04-30 |
| CN1942579B (zh) | 2013-06-26 |
| US7811801B2 (en) | 2010-10-12 |
| JP5657850B2 (ja) | 2015-01-21 |
| US20070009990A1 (en) | 2007-01-11 |
| US20050227318A1 (en) | 2005-10-13 |
| IL206889A0 (en) | 2010-12-30 |
| US7494796B2 (en) | 2009-02-24 |
| IL174947A (en) | 2011-11-30 |
| US8008041B2 (en) | 2011-08-30 |
| EP1687401B1 (en) | 2012-11-21 |
| US20090298124A1 (en) | 2009-12-03 |
| AU2004282577A1 (en) | 2005-04-28 |
| US8114654B2 (en) | 2012-02-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 9A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2260 DE 29/04/2014. |