BRPI0415308A - incorporação especìfica de local de aminoácidos redox ativos em proteìnas - Google Patents
incorporação especìfica de local de aminoácidos redox ativos em proteìnasInfo
- Publication number
- BRPI0415308A BRPI0415308A BRPI0415308-1A BRPI0415308A BRPI0415308A BR PI0415308 A BRPI0415308 A BR PI0415308A BR PI0415308 A BRPI0415308 A BR PI0415308A BR PI0415308 A BRPI0415308 A BR PI0415308A
- Authority
- BR
- Brazil
- Prior art keywords
- amino acids
- proteins
- active redox
- redox amino
- site
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 5
- 108090000623 proteins and genes Proteins 0.000 title abstract 5
- 150000001413 amino acids Chemical class 0.000 title abstract 4
- 238000010348 incorporation Methods 0.000 title 1
- 108020004566 Transfer RNA Proteins 0.000 abstract 2
- 102000052866 Amino Acyl-tRNA Synthetases Human genes 0.000 abstract 1
- 108700028939 Amino Acyl-tRNA Synthetases Proteins 0.000 abstract 1
- 102000003960 Ligases Human genes 0.000 abstract 1
- 108090000364 Ligases Proteins 0.000 abstract 1
- 125000000266 alpha-aminoacyl group Chemical group 0.000 abstract 1
- 230000001851 biosynthetic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51153203P | 2003-10-14 | 2003-10-14 | |
| PCT/US2004/034089 WO2005038002A2 (en) | 2003-10-14 | 2004-10-13 | Site-specific incorporation of redox active amino acids into proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0415308A true BRPI0415308A (pt) | 2006-12-05 |
Family
ID=34465242
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0415308-1A BRPI0415308A (pt) | 2003-10-14 | 2004-10-13 | incorporação especìfica de local de aminoácidos redox ativos em proteìnas |
Country Status (14)
| Country | Link |
|---|---|
| US (5) | US8008041B2 (enExample) |
| EP (1) | EP1687401B1 (enExample) |
| JP (1) | JP5657850B2 (enExample) |
| CN (2) | CN1942579B (enExample) |
| AU (1) | AU2004282577B2 (enExample) |
| BR (1) | BRPI0415308A (enExample) |
| CA (1) | CA2541166A1 (enExample) |
| DK (1) | DK1687401T3 (enExample) |
| ES (1) | ES2396712T3 (enExample) |
| IL (3) | IL174947A (enExample) |
| MX (1) | MXPA06004087A (enExample) |
| PL (1) | PL1687401T3 (enExample) |
| PT (1) | PT1687401E (enExample) |
| WO (1) | WO2005038002A2 (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA03009566A (es) * | 2001-04-19 | 2004-12-06 | Scripps Research Inst | Metodos y composicion para la produccion de pares trna-aminoaciltrna sintetasa ortogonales. |
| KR20050073559A (ko) * | 2002-10-16 | 2005-07-14 | 더 스크립스 리서치 인스티튜트 | 당단백질 합성 |
| KR101171397B1 (ko) * | 2003-04-17 | 2012-08-07 | 더 스크립스 리서치 인스티튜트 | 진핵 유전자 코드의 확장 |
| CA2527877A1 (en) | 2003-06-18 | 2005-01-13 | The Scripps Research Institute | Unnatural reactive amino acid genetic code additions |
| ATE386133T1 (de) * | 2003-07-07 | 2008-03-15 | Scripps Research Inst | Zusammensetzungen der orthogonalen lysyl-trna und aminoacyl-trna synthetase paaren und ihre verwendungen |
| US7399619B2 (en) * | 2004-05-25 | 2008-07-15 | The Scripps Research Institute | Site specific incorporation of heavy atom-containing unnatural amino acids into proteins for structure determination |
| DE102004031258A1 (de) * | 2004-06-29 | 2006-02-09 | Jennissen, Herbert P., Prof. Dr. | Proteinhybride mit polyhydroxyaromatischen Aminosäure-Epitopen |
| US20060110784A1 (en) * | 2004-09-22 | 2006-05-25 | The Scripps Research Institute | Site-specific labeling of proteins for NMR studies |
| WO2006110182A2 (en) | 2004-10-27 | 2006-10-19 | The Scripps Research Institute | Orthogonal translation components for the in vivo incorporation of unnatural amino acids |
| BRPI0617191A2 (pt) * | 2005-10-12 | 2011-07-19 | Scripps Research Inst | modificação pós-traducional de polipeptìdeos expressos em fagos |
| US7776535B2 (en) | 2006-02-06 | 2010-08-17 | Franklin And Marshall College | Site-specific incorporation of fluorinated amino acids into proteins |
| EP1991680B1 (en) | 2006-03-09 | 2013-08-21 | The Scripps Research Institute | System for the expression of orthogonal translation components in eubacterial host cells |
| US7790847B2 (en) * | 2006-03-16 | 2010-09-07 | The Scripps Research Institute | Genetically programmed expression of proteins containing the unnatural amino acid phenylselenocysteine |
| CA2652894A1 (en) * | 2006-05-23 | 2007-12-06 | The Scripps Research Institute | Genetically encoded fluorescent coumarin amino acids |
| WO2008036392A2 (en) | 2006-09-21 | 2008-03-27 | The Scripps Research Institute | Genetically programmed expression of selectively sulfated proteins in eubacteria |
| RU2009112104A (ru) | 2006-10-18 | 2010-11-27 | Зе Скрипс Ресеч Инститьют (Us) | Генетическое встраивание не встречающихся в природе аминокислот в белки клеток млекопитающих |
| WO2008137452A1 (en) * | 2007-05-04 | 2008-11-13 | Kenergy Royalty Company, Llc | Implantable high efficiency digital stimulation device |
| MX2010004464A (es) | 2007-10-25 | 2010-06-07 | Scripps Research Inst | Incorporacion genetica de 3-aminotirosina a reductasas. |
| US20090148887A1 (en) * | 2007-11-02 | 2009-06-11 | The Scripps Research Institute | Genetically encoded boronate amino acid |
| US9249408B2 (en) * | 2007-11-02 | 2016-02-02 | The Scripps Research Institute | Directed evolution using proteins comprising unnatural amino acids |
| BRPI0819929A2 (pt) | 2007-12-11 | 2014-10-14 | Scripps Research Inst | Expressão de amino ácido não natural em vivo na levedura pichia pastoris metilotrófica |
| US8318172B2 (en) * | 2008-02-08 | 2012-11-27 | The Scripps Research Institute | Breaking immunological tolerance with a genetically encoded unnatural amino acid |
| AU2009333554A1 (en) * | 2008-12-09 | 2011-06-30 | Cook Medical Technologies Llc | Apparatus and methods for controlled release of tacking devices |
| US20090197339A1 (en) * | 2008-12-10 | 2009-08-06 | The Scripps Research Institute | In vivo unnatural amino acid expression in the methylotrophic yeast pichia pastoris |
| US8609383B2 (en) | 2008-12-10 | 2013-12-17 | The Scripps Research Institute | Production of carrier-peptide conjugates using chemically reactive unnatural amino acids |
| WO2010089741A1 (en) * | 2009-02-04 | 2010-08-12 | Ben-Gurion University Of The Negev Research And Development Authority | Systems and methods for bio-electricity production |
| JP6574754B2 (ja) | 2013-03-19 | 2019-09-11 | ベイジン シェノゲン ファーマ グループ リミテッド | エストロゲン受容体関連疾患を処置するための抗体及び方法 |
| US20150331624A1 (en) * | 2014-05-19 | 2015-11-19 | Kabushiki Kaisha Toshiba | Host-controlled flash translation layer snapshot |
| KR101956042B1 (ko) * | 2017-07-13 | 2019-03-08 | 서강대학교산학협력단 | 표적 단백질 내 l-디하이드록시페닐알라닌의 도입 방법 |
| EP3983501B1 (en) | 2019-06-17 | 2025-02-26 | Merck Patent GmbH | Liquid crystal-based light valve |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5879905A (en) * | 1996-08-29 | 1999-03-09 | Massachusetts Institute Of Technology | In vivo method of initiating protein synthesis with an amino acid other than methionine |
| MXPA03009566A (es) * | 2001-04-19 | 2004-12-06 | Scripps Research Inst | Metodos y composicion para la produccion de pares trna-aminoaciltrna sintetasa ortogonales. |
| ATE526414T1 (de) | 2002-10-16 | 2011-10-15 | Scripps Research Inst | Ortsspezifische einbindung von ketoaminosäuren in proteine |
| KR20050073559A (ko) | 2002-10-16 | 2005-07-14 | 더 스크립스 리서치 인스티튜트 | 당단백질 합성 |
| US7642085B2 (en) | 2002-12-22 | 2010-01-05 | The Scripps Research Institute | Protein arrays |
| KR101171397B1 (ko) | 2003-04-17 | 2012-08-07 | 더 스크립스 리서치 인스티튜트 | 진핵 유전자 코드의 확장 |
| CA2527877A1 (en) | 2003-06-18 | 2005-01-13 | The Scripps Research Institute | Unnatural reactive amino acid genetic code additions |
| ATE386133T1 (de) | 2003-07-07 | 2008-03-15 | Scripps Research Inst | Zusammensetzungen der orthogonalen lysyl-trna und aminoacyl-trna synthetase paaren und ihre verwendungen |
| WO2005007870A2 (en) | 2003-07-07 | 2005-01-27 | The Scripps Research Institute | COMPOSITIONS OF ORTHOGONAL LEUCYL-tRNA AND AMINOACYL-tRNA SYNTHETASE PAIRS AND USES THEREOF |
| US7527943B2 (en) | 2003-07-07 | 2009-05-05 | The Scripps Research Institute | Compositions of orthogonal glutamyl-tRNA and aminoacyl-tRNA synthetase pairs and uses thereof |
-
2004
- 2004-10-13 BR BRPI0415308-1A patent/BRPI0415308A/pt not_active IP Right Cessation
- 2004-10-13 WO PCT/US2004/034089 patent/WO2005038002A2/en not_active Ceased
- 2004-10-13 PL PL04795276T patent/PL1687401T3/pl unknown
- 2004-10-13 MX MXPA06004087A patent/MXPA06004087A/es active IP Right Grant
- 2004-10-13 AU AU2004282577A patent/AU2004282577B2/en not_active Ceased
- 2004-10-13 CA CA002541166A patent/CA2541166A1/en not_active Abandoned
- 2004-10-13 CN CN2004800301376A patent/CN1942579B/zh not_active Expired - Fee Related
- 2004-10-13 CN CN200910004743A patent/CN101532046A/zh active Pending
- 2004-10-13 DK DK04795276.7T patent/DK1687401T3/da active
- 2004-10-13 EP EP04795276A patent/EP1687401B1/en not_active Expired - Lifetime
- 2004-10-13 PT PT47952767T patent/PT1687401E/pt unknown
- 2004-10-13 US US10/575,991 patent/US8008041B2/en not_active Expired - Lifetime
- 2004-10-13 ES ES04795276T patent/ES2396712T3/es not_active Expired - Lifetime
- 2004-10-13 US US10/965,218 patent/US7494796B2/en not_active Expired - Lifetime
- 2004-10-13 JP JP2006535350A patent/JP5657850B2/ja not_active Expired - Fee Related
-
2006
- 2006-04-11 IL IL174947A patent/IL174947A/en not_active IP Right Cessation
-
2008
- 2008-12-17 US US12/317,034 patent/US7811801B2/en not_active Expired - Lifetime
-
2009
- 2009-10-22 IL IL201705A patent/IL201705A0/en unknown
-
2010
- 2010-07-08 IL IL206889A patent/IL206889A0/en unknown
- 2010-08-20 US US12/806,751 patent/US8114654B2/en not_active Expired - Lifetime
-
2012
- 2012-01-05 US US13/344,436 patent/US9783798B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20050227318A1 (en) | 2005-10-13 |
| US20120100570A1 (en) | 2012-04-26 |
| US20090298124A1 (en) | 2009-12-03 |
| WO2005038002A2 (en) | 2005-04-28 |
| CN1942579B (zh) | 2013-06-26 |
| CN1942579A (zh) | 2007-04-04 |
| US8114654B2 (en) | 2012-02-14 |
| EP1687401A2 (en) | 2006-08-09 |
| IL201705A0 (en) | 2011-08-01 |
| JP2007508034A (ja) | 2007-04-05 |
| WO2005038002A3 (en) | 2006-11-23 |
| JP5657850B2 (ja) | 2015-01-21 |
| AU2004282577B2 (en) | 2009-10-29 |
| MXPA06004087A (es) | 2006-06-27 |
| US8008041B2 (en) | 2011-08-30 |
| US9783798B2 (en) | 2017-10-10 |
| IL174947A0 (en) | 2006-08-20 |
| IL206889A0 (en) | 2010-12-30 |
| US7811801B2 (en) | 2010-10-12 |
| PL1687401T3 (pl) | 2013-04-30 |
| US20110008782A1 (en) | 2011-01-13 |
| DK1687401T3 (da) | 2013-02-04 |
| CA2541166A1 (en) | 2005-04-28 |
| ES2396712T3 (es) | 2013-02-25 |
| EP1687401A4 (en) | 2007-08-01 |
| US20070009990A1 (en) | 2007-01-11 |
| US7494796B2 (en) | 2009-02-24 |
| AU2004282577A1 (en) | 2005-04-28 |
| IL174947A (en) | 2011-11-30 |
| PT1687401E (pt) | 2013-02-26 |
| EP1687401B1 (en) | 2012-11-21 |
| CN101532046A (zh) | 2009-09-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 9A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2260 DE 29/04/2014. |